The plant hormone abscisic acid stimulates the proliferation of human hemopoietic progenitors through the second messenger cyclic ADP-ribose

Stem Cells

Volumn 27, Issue 10, 2009, Pages 2469-2477

  Scarfì, Sonia ^a,b   Fresia, Chiara ^a,b   Ferraris, Chiara ^a,b   Bruzzone, Santina ^b   Fruscione, Floriana ^a   Usai, Cesare ^c   Benvenuto, Federica ^b   Magnone, Mirko ^b   Podestà, Marina ^d   Sturla, Laura ^b   Guida, Lucrezia ^b   Albanesi, Ennio ^e   Damonte, Gianluca ^b   Salis, Annalisa ^b   De Flora, Antonio ^b   Zocchi, Elena ^a,b  

^a ADVANCED BIOTECHNOLOGY CENTER   (Italy)

^b UNIVERSITY OF GENOA   (Italy)

^c CNR   (Italy)

^d UNIVERSITY OF GENOA   (Italy)

^e G GASLINI INSTITUTE   (Italy)

Author keywords

Abscisic acid; Cyclic ADP ribose; Hemopoietic progenitors; Intracellular calcium; Mesenchymal stem cells

Indexed keywords

ABSCISIC ACID; ADENOSINE DIPHOSPHATE RIBOSYL CYCLASE; CALCIUM; CALCIUM ION; CD34 ANTIGEN; CHEMOKINE RECEPTOR CXCR4; COLONY STIMULATING FACTOR 1; CYCLIC ADENOSINE DIPHOSPHATE RIBOSE; CYTOKINE; FAS LIGAND; FLT3 LIGAND; HEMOPOIETIC GROWTH FACTOR; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERLEUKIN 16; INTERLEUKIN 1BETA; INTERLEUKIN 6; INTERLEUKIN 8; INTERLEUKIN 9; MACROPHAGE INFLAMMATORY PROTEIN 1ALPHA; MACROPHAGE INFLAMMATORY PROTEIN 1BETA; MELANOMA GROWTH STIMULATORY ACTIVITY FACTOR; MONOCLONAL ANTIBODY; PHYTOHORMONE; RANTES; SOMATOMEDIN C; STRESS HORMONE; THROMBOCYTE FACTOR 4; TRANSFORMING GROWTH FACTOR BETA1; VASCULOTROPIN;

ARTICLE; CALCIUM CELL LEVEL; CELL PROLIFERATION; COCULTURE; COLONY FORMATION; CONTROLLED STUDY; CYTOKINE RELEASE; GENETIC TRANSCRIPTION; HEMATOPOIETIC STEM CELL; HUMAN; HUMAN CELL; IN VITRO STUDY; LYMPHOCYTE CULTURE; PROTEIN SECRETION; SECOND MESSENGER; SIGNAL TRANSDUCTION;

ABSCISIC ACID; ANTIGENS, CD34; CALCIUM; CALCIUM SIGNALING; CELL PROLIFERATION; CELLS, CULTURED; CULTURE MEDIA, CONDITIONED; CYCLIC ADP-RIBOSE; CYTOKINES; HEMATOPOIETIC STEM CELLS; HUMANS; MESENCHYMAL STEM CELLS; NEOVASCULARIZATION, PHYSIOLOGIC; NF-KAPPA B; PLANT GROWTH REGULATORS; SECOND MESSENGER SYSTEMS; SIGNAL TRANSDUCTION; TRANSCRIPTIONAL ACTIVATION;

EMBRYOPHYTA;

EID: 70350246121     PISSN: 10665099     EISSN: None     Source Type: Journal    
DOI: 10.1002/stem.173     Document Type: Article

References (41)

1. Dazzi F, Ramasamy R, Glennie S et al. The role of mesenchymal stem cells in haemopoiesis. Blood Rev 2006;20:161-171.
2. +-mobilizing activity. J Biol Chem 1989;264(3):1608-1615.
3. Podestà M, Zocchi E, Pitto A et al. Extracellular cyclic ADP-ribose increases intracellular free calcium concentration and stimulates proliferation of human hemopoietic progenitors. FASEB J 2000;14:680-690. (Pubitemid 30198567)
4. Zocchi E, Podestà M, Pitto A et al. Paracrinally stimulated expansion of early human hemopoietic progenitors by stroma-generated cyclic ADP-ribose. FASEB J 2001;15(9):1610-1612.
5. Podestà M, Pitto A, Figari O et al. Cyclic ADP-ribose generation by CD38 improves human hemopoietic stem cell engraftment into NOD/SCID mice. FASEB J 2003;17:310-312.
6. + stroma stimulates proliferation of human hematopoietic progenitors. J Biol Chem 2005;280:5343-5349.
7. Netting AG. pH, abscisic acid and the integration of metabolism in plants under stressed and non-stressed conditions. II. Modifications in modes of metabolism induced by variation in the tension on the water column and by stress. J Exp Bot 2002;53(367):151-173.
8. Himmelbach A, Yang Y, Grill E. Relay and control of abscisic acid signaling. Curr Opin Plant Biol 2003;6:470-479. (Pubitemid 37195749)
9. Zocchi E, Carpaneto A, Cerrano C et al. The temperature-signaling cascade in sponges involves a heat-gated cation channel, abscisic acid, and cyclic ADP-ribose. Proc Natl Acad Sci U S A 2001;98(26):14859-14864. (Pubitemid 34013935)
10. Zocchi E, Basile G, Cerrano C et al. ABA- and cADPR-mediated effects on respiration and filtration downstream of the temperature-signaling cascade in sponges. J Cell Sci 2003;116:629-636. (Pubitemid 36231301)
11. Puce S, Basile G, Bavestrello G et al. Abscisic acid signaling through cyclic ADP-ribose in hydroid regeneration. J Biol Chem 2004;279: 39783-39788. (Pubitemid 39258248)
12. Bruzzone S, Moreschi I, Usai C et al. Abscisic acid is an endogenous cytokine in human granulocytes with cyclic ADP-ribose as second messenger. Proc Natl Acad Sci U S A 2007;104:5759-5764. (Pubitemid 47175607)
13. Bruzzone S, Bodrato N, Usai C et al. Abscisic acid is an endogenous stimulator of insulin release from human pancreatic islets with cyclic ADP ribose as second messenger. J Biol Chem 2008;283(47):32188-32197.
14. Scarfì S, Ferraris C, Fruscione F et al. Cyclic ADP-ribose-mediated expansion and stimulation of human mesenchymal stem cells by the plant hormone abscisic acid. Stem Cells 2008;26(11):2855-2864.
15. Graeff R, Lee HC. A novel cycling assay for cellular cADP-ribose with nanomolar sensitivity. Biochem J 2002;361(Pt 2):379-384. (Pubitemid 34174505)
16. Bradford MM. A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding. Anal Biochem 1976;72:248-252.
17. Wagemaker G, Neelis KJ, Wognum AW. Surface markers and growth factor receptors of immature hemopoietic stem cell subsets. Stem Cells 1995;13:165-171.
18. Sutherland HJ, Eaves CJ, Eaves AC et al. Characterization and partial purification of human marrow cells capable of initiating long term haemopoiesis in vitro. Blood 1989;74:1563-1570.
19. Sutherland HJ, Eaves CJ, Landsdorp PM et al. Differential regulation of primitive human hematopoietic cells in long-term cultures maintained on genetically engineered murine stromal cells. Blood 1991;78: 666-672.
20. 2+ release. Biochim Biophys Acta 1993; 1178:235-242.
21. Pyatt DW, Stillman WS, Yang Y et al. An essential role for NF-kappaB in human CD34(+) bone marrow cell survival. Blood 1999; 93(10):3302-3308. (Pubitemid 29220897)
22. Aggarwal S, Pittenger MF. Human mesenchymal stem cells modulate allogeneic immune cell responses. Blood 2005;105:1815-1822. (Pubitemid 40223708)
23. + cells, myeloblasts, erythroblasts and megakaryoblasts and regulate normal hematopoiesis in an autocrine/paracrine manner. Blood 2001;97(10):3075-3085.
24. Minehata K, Takeuchi M, Hirabayashi Y et al. Oncostatin m maintains the hematopoietic microenvironment and retains hematopoietic progenitors in the bone marrow. Int J Hematol 2006;84(4):319-327. (Pubitemid 46606573)
25. Vandervelde S, van Luyn MJ, Tio RA et al. Signaling factors in stem cell-mediated repair of infarcted myocardium. J Mol Cell Cardiol 2005;39(2):363-376. (Pubitemid 40995026)
26. Bobrovnikova-Marjon EV,Marjon PL, Barbash O et al. Expression of angiogenic factors vascular endothelial growth factor and interleukin-8/CXCL8 is highly responsive to ambient glutamine availability: role of nuclear factor-kappaB and activating protein-1. Cancer Res 2004;64(14):4858-4869. (Pubitemid 38924530)
27. Altinoz MA, Korkmaz R. NF-kappaB, macrophage migration inhibitory factor and cyclooxygenase-inhibitions as likely mechanisms behind the acetaminophen- and NSAID-prevention of the ovarian cancer. Neoplasma 2004;51(4):239-247. (Pubitemid 38915539)
28. Stassen M, Müller C, Arnold M et al. IL-9 and IL-13 production by activated mast cells is strongly enhanced in the presence of lipopolysaccharide: NF-kappaB is decisively involved in the expression of IL-9. J Immunol 2001;166(7):4391-4398. (Pubitemid 32233721)
29. Kim HR, Hwang KA, Park SH et al. Crit Rev Immunol 2008;28(4):325-339.
30. Grumont RJ, Rourke IJ, Gerondakis S. Rel-dependent induction of A1 transcription is required to protect B cells from antigen receptor ligation- induced apoptosis. Genes Dev 1999;13(4):400-411. (Pubitemid 29108756)
31. Cazals V, Nabeyrat E, Corroyer S et al. Role for NF-kappa B in mediating the effects of hyperoxia on IGF-binding protein 2 promoter activity in lung alveolar epithelial cells. Biochim Biophys Acta 1999; 1448(3):349-362. (Pubitemid 29070859)
32. Crisostomo PR, Wang Y, Markel TA et al. Human mesenchymal stem cells stimulated by TNF-alpha, LPS or hypoxia produce growth factors by an NF kappa B- but not JNK-dependent mechanism. Am J Physiol Cell Physiol 2008;294(3):C675- 682.
33. 2+ influx is an essential component of the positive-feedback loop that maintains leading-edge structure and activity in macrophages. Proc Natl Acad Sci U S A 2007;104(41):16176-16181.
34. Okuno Y, Iwasaki H, Huettner CS et al. Differential regulation of the human and murine CD34 genes in hematopoietic stem cells. Proc Natl Acad Sci U S A 2002;99(9):6246-6251. (Pubitemid 34493297)
35. Takihara Y, Hara J. Polycomb-group genes and hematopoiesis. Int J Hematol 2000;72(2):165-172.
36. Guzman ML, Neering SJ, Upchurch D et al. Nuclear factor-kappaB is constitutively activated in primitive human acute myelogenous leukemia cells. Blood 2001;98(8):2301-2307.
37. Braun T, Carvalho G, Coquelle A et al. NF-kappaB constitutes a potential therapeutic target in high-risk myelodysplastic syndrome. Blood 2006;107(3):1156-1165. (Pubitemid 43156318)
38. Soderling TR. The Ca-calmodulin-dependent protein kinase cascade. Trends Biochem Sci 1999;24(6):232-236.
39. Popovic R, Zeleznik-Le NJ. MLL: How complex does it get? J Cell Biochem 2005;95(2):234-242.
40. Schraets D, Lehmann T, Dingermann T et al. MLL-mediated transcriptional gene regulation investigated by gene expression profiling. Oncogene 2003;22(23):3655-3668. (Pubitemid 36765325)
41. Emerson SG. Ex vivo expansion of hematopoietic precursors, progenitors, and stem cells: the next generation of cellular therapeutics. Blood 1996;87:3082-3088.