Editorial: Nephropharmacology: Drugs and the kidney

Clinical Pharmacology and Therapeutics

Volumn 86, Issue 5, 2009, Pages 453-456

  Atkinson, A J ^a   Huang, S M ^b  

^a NORTHWESTERN UNIVERSITY   (United States)

^b CENTER FOR DRUG EVALUATION AND RESEARCH   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BROMIDE; CREATININE; IMMUNOSUPPRESSIVE AGENT; WARFARIN; DRUG;

CONTINUOUS RENAL REPLACEMENT THERAPY; CREATININE BLOOD LEVEL; CREATININE CLEARANCE; DOSE CALCULATION; DOSE RESPONSE; DRUG DOSE; DRUG MONITORING; EDITORIAL; GLOMERULUS FILTRATION RATE; HUMAN; KIDNEY; KIDNEY FAILURE; KIDNEY GRAFT REJECTION; NEPHROTOXICITY; PHARMACOGENETICS; PRIORITY JOURNAL; KIDNEY DISEASE; METABOLISM; PATHOPHYSIOLOGY; PHARMACOKINETICS;

DOSE-RESPONSE RELATIONSHIP, DRUG; HUMANS; KIDNEY DISEASES; PHARMACEUTICAL PREPARATIONS; PHARMACOGENETICS; PHARMACOKINETICS;

EID: 70350214951     PISSN: 00099236     EISSN: 15326535     Source Type: Journal    
DOI: 10.1038/clpt.2009.191     Document Type: Editorial

References (20)

1. Huang, S-M. & Temple, R. Is this the drug or dose for you?: impact and consideration of ethnic factors in global drug development, regulatory review, and clinical practice. Clin. Pharmacol. Ther. 84, 287-294 (2008).
2. Lesko, L.J. The critical path of warfarin dosing: finding an optimal dosing strategy using pharmacogenetics. Clin. Pharmacol. Ther. 84, 301-305 (2008).
3. Wuth, O. Rational bromide treatment: new methods for its control. JAMA 88, 2013-2017 (1927).
4. Dettli, L. Individualization of drug dosage in patients with renal disease. Med. Clin. North Am. 58, 977-985 (1974).
5. Brenner, B.M. Nephron adaptation to renal injury or ablation. Am. J. Physiol. 249, F324-F337 (1985).
6. Nolin, T.D., Naud, J., Leblond, F.A. & Pichette V. Emerging evidence of the impact of kidney disease on drug metabolism and transport. Clin. Pharmacol. Ther. 83, 898-903 (2008).
7. Dreisbach, A.W. The influence of chronic renal failure on drug metabolism and transport. Clin. Pharmacol. Ther. 86, 553-556 (2009).
8. Huang, S.-M., Temple, R., Xiao, S., Zhang, L. & Lesko, L.J. When to conduct a renal impairment study during drug development: US Food and Drug Administration perspective. Clin. Pharmacol. Ther. 86, 475-479 (2009).
9. Atkinson, A.J. Jr. & Umans, J.G. Pharmacokinetic studies in hemodialysis patients. Clin. Pharmacol. Ther. 86, 548-552 (2009).
10. Susla, G.M. The impact of continuous renal replacement therapy on drug therapy. Clin. Pharmacol. Ther. 86, 562-565 (2009).
11. Mueller, B.A. & Smoyer, W.E. Challenges in developing evidence-based drug dosing guidelines for adults and children receiving renal replacement therapy. Clin. Pharmacol. Ther. 86, 479-482 (2009).
12. Lalonde, R.L. & Wagner, J.A. Drug development perspective on pharmacokinetic studies of new drugs in patients with renal impairment. Clin. Pharmacol. Ther. 86, 557-561 (2009).
13. Brater, D.C. Drug dosing in patients with impaired renal function. Clin. Pharmacol. Ther. 86, 483-489 (2009).
14. Stevens, L.A. & Levey, A.S. Use of the MDRD Study equation to estimate kidney function for drug dosing. Clin. Pharmacol. Ther. 86, 465-467 (2009).
15. Spruill, W.J., Wade, W.E. & Cobb, H.H. III. Continuing the use of the Cockcroft-Gault equation for drug dosing in patients with impaired renal function. Clin. Pharmacol. Ther. 86, 468-470 (2009).
16. Weiner, D.E. Public health consequences of chronic kidney disease. Clin. Pharmacol. Ther. 86, 566-569 (2009).
17. Himmelfarb, J. Dialysis at a crossroads: reverse engineering renal replacement therapy. Clin. J. Am. Soc. Nephrol. 1, 896-902 (2006).
18. Goodsaid, F.M. et al. Novel biomarkers of acute kidney toxicity. Clin. Pharmacol. Ther. 86, 490-496 (2009).
19. Throckmorton, D.C. How a US regulator can encourage new science. Clin. Pharmacol. Ther. 86, 471-472 (2009).
20. Atkinson, A.J. Jr. & Reidenberg, M.M. Effects of renal disease on pharmacokinetics. In Principles of Clinical Pharmacology 2nd edn. (eds. Atkinson, A.J. Jr., Abernethy, D.R., Daniels, C.E., Dedrick, R.L. & Markey, S.P.) 51-58 (Academic Press/Elsevier, San Diego, CA, 2007).