Designing bioresorbable polyester matrices for controlled doxorubicin release in glioma therapy

International Journal of Pharmaceutics

Volumn 382, Issue 1-2, 2009, Pages 124-129

  Kasperczyk, J ^a,b   Stoklosa, K ^a   Dobrzynski, P ^b   Stepien, K ^a   Kaczmarczyk, B ^b   Dzierzega Lecznar, A ^a  

^a MEDICAL UNIVERSITY OF SILESIA   (Poland)

^b CENTRE OF POLYMER AND CARBON MATERIALS   (Poland)

Author keywords

Chain microstructure; Controlled release; Degradation; Drug delivery systems; NMR

Indexed keywords

COPOLYMER; DOXORUBICIN; POLY(GLYCOLIDE CO EPSILON CAPROLACTONE); POLYGLACTIN; UNCLASSIFIED DRUG;

ARTICLE; CANCER CHEMOTHERAPY; CHEMICAL INTERACTION; CONTROLLED DRUG RELEASE; CONTROLLED STUDY; DEGRADATION KINETICS; DRUG DELIVERY SYSTEM; DRUG DESIGN; DRUG STABILITY; GLIOMA; INFRARED SPECTROSCOPY; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; PRIORITY JOURNAL;

ANIMALS; ANTIBIOTICS, ANTINEOPLASTIC; BRAIN NEOPLASMS; CEREBROSPINAL FLUID; CHEMISTRY, PHARMACEUTICAL; DELAYED-ACTION PREPARATIONS; DOXORUBICIN; DRUG CARRIERS; DRUG COMPOUNDING; GLIOMA; HUMANS; HYDROLYSIS; KINETICS; LACTIC ACID; MAGNETIC RESONANCE SPECTROSCOPY; MOLECULAR CONFORMATION; POLYESTERS; POLYGLYCOLIC ACID; SOLUBILITY; SPECTROSCOPY, FOURIER TRANSFORM INFRARED; TECHNOLOGY, PHARMACEUTICAL;

EID: 70350211852     PISSN: 03785173     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ijpharm.2009.08.022     Document Type: Article

References (29)

1. Azizi S.A., and Miyamoto C. Principles of treatment of malignant gliomas in adults: an overview. J. Neurovirol. 4 (1998) 204-216
2. Buntner B., Nowak M., Kasperczyk J., Ryba M., Grieb P., Walski W., Dobrzynski P., and Bero M. The application of microspheres from the copolymers of lactide and ε-caprolactone to the controlled release of steroids. J. Control. Release 56 (1998) 159-167
3. Ciccarelli E., Miola C., Grottoli S., Avataneo T., Lancranjan I., and Cammanni F. Long term therapy of patients with macroprolactinoma using repeatable injectable bromocriptine. J. Clin. Endocrinol. Metab. 76 (1993) 484-488
4. 4. Macromolecules 34 (2001) 5090-5098
5. Dobrzynski P., Li S., Kasperczyk J., Bero M., Gasc F., and Vert M. Structure-property relationships of copolymers obtained by ring-opening polymerization of glycolide and ε-caprolactone. Part 1. Synthesis and characterization. Biomacromolecules 6 (2005) 483-488
6. Dobrzynski P., Kasperczyk J., Ryba M., Walski M., Jelonek K., and Bero M. Application of the lithium and magnesium initiators for the synthesis of glycolide, lactide and ε-caprolactone copolymers biocompatible with brain tissue. J. Biomed. Mater. Res. Part A 79 (2006) 865-873
7. Harish B., Ravivarapu H.B., Moyer K.L., and Dunn R.L. Sustained activity and release of leuprolide acetate from an in situ forming polymeric implant. AAPS PharmSciTech. 1 (2000)
8. Hu Y., He Y., Wei J., Fan Z., Dobrzyński P., Kasperczyk J., Bero M., and Li S. Hydrolytic degradation of glycolide/l-lactide/ε-caprolactone terpolymers initiated by zirconium (IV) acetylacetonate. J. Appl. Polym. Sci. 103 (2007) 2451-2456
9. Huynh G.H., Deen D.F., and Szoka Jr. F.C. Barriers to carrier mediated drug and gene delivery to brain tumors. J. Control. Release 110 (2006) 236-259
10. Jaworska J., Kasperczyk J., and Dobrzynski P. Degradation process of bioresorbable copolyesters. Microstructure investigation by NMR and ESI-MS. Macromol. Symp. 253 (2007) 40-46
11. Jonat W., Kaufmann M., Sauerbrei W., Blamey R., Cuzick J., Namer M., Fogelman I., Haes J.C., Matteis A., Stewart A., Eiermann W., Szakolczai I., Palmer M., Schumacher M., Geberth M., and Lisboa B. Goserelin versus cyclophosphamide, methotrexate, and fluorouracil as adjuvant therapy in premenopausal patients with node-positive breast cancer: the 'Zoladex' Early Breast Cancer Research Association study. J. Clin. Oncol. 20 (2002) 4628-4635
12. 13C] NMR spectroscopy. Polymer 37 (1996) 201-203
13. 13C NMR spectroscopy. Macromol. Chem. Phys. 200 (1999) 903-910
14. Kasperczyk J., Hu Y., Jaworska J., Dobrzynski P., Wei J., and Li S. Comparative study of the hydrolytic degradation of glycolide/l-lactide/e-caprolactone: terpolymers initiated by zirconium (IV) acetylacetonate or stannous octoate. J. Appl. Polym. Sci. 107 (2008) 3258-3266
15. Kasperczyk J., Jelonek K., Dobrzynski P., and Jarza{ogonek}bek B. The influence of copolymer chain microstructure on cyclosporine a (CyA) and Sirolimus prolonged and sustained release from PLA/TMC and PLA/PCL matrices. J. Control. Release 116 (2006) e5-e6
16. Kasperczyk J., Li S., Jaworska J., Dobrzynski P., and Vert M. Degradation of copolymers obtained by ring-opening polymerization of glycolide and e-caprolactone: a high resolution NMR and ESI-MS study. Polym. Degrad. Stab. 93 (2008) 990-999
17. Kryczka T., Bero M., Kasperczyk J., Dobrzynski P., Marciniec B., Popelarz-Brzezińska M., and Grieb P. In vitro release of cytotoxic nucleoside analogs from lactide-caprolactone and lactide-glycolide copolymers. Acta Biochim. Pol. 49 (2002) 205-210
18. Lesniak M.S., Upadhyay U., Goodwin R., Tyler B., and Brem H. Local delivery of doxorubicin for the treatment of malignant brain tumors in rats. Anticancer Res. 25 (2005) 3825-3831
19. Li S., Dobrzynski P., Kasperczyk J., Bero M., Braud Ch., and Vert M. Structure-property relationships of copolymers obtained by ring-opening polymerization of glycolide and ε-caprolactone. Part 2. Influence of composition and chain microstructure on the hydrolytic degradation. Biomacromolecules 6 (2005) 489-497
20. Li S. Hydrolytic degradation characteristics of aliphatic polyesters derived from lactic and glycolic acids. J. Biomed. Mater. Res.: Appl. Biomat. 48 (1999) 342-353
21. Lin R., Ng L.S., and Wang Ch.-H. In vitro study of anticancer drug doxorubicin in PLGA-based microparticles. Biomaterials 26 (2005) 4476-4485
22. Maciejowska J., Kasperczyk J., Dobrzynski P., and Bero M. The influence of chain microstructure on hydrolytic degradation of glycolide/lactide copolymers used in drug delivery systems. J. Control. Release 116 (2006) e6-e8
23. Manome Y., Kobayashi T., Mori M., Suzuki R., Funamizu N., Akiyama N., Inoue S., Tabata Y., and Watanabe M. Local delivery of doxorubicin for malignant glioma by a biodegradable PLGA polymer sheet. Anticancer Res. 26 (2006) 3317-3326
24. Muldoon L.L., and Neuwelt E.A. BR96-DOX immunoconjugate targeting of chemotherapy in brain tumor models. J. Neurooncol. 65 (2003) 49-62
25. Plosker G.L., and Brodgen R.N. Leuprorelin. A review of pharmacology and therapeutic use in prostate cancer, endometriosis and other sex hormone-related disorders. Drugs 48 (1994) 930-967
26. 2+) on acetylcholine-induced currents in greater pond snail neurons. Neurosci. Behav. Physiol. 30 (2000) 63-67
27. Schwach G., Coudane J., Engel R., and Vert M. More about the polymerization of lactides in the presence of stannous octoate. J. Polym. Sci. Part A: Polym. Chem. 35 (1997) 3431-3440
28. Wagner S., Peters O., Fels Ch., Janssen G., Liebeskind A.K., Sauerbrey A., Suttorp M., Hau P., and Wolff J.E. Pegylated-liposomal doxorubicin and oral topotecan in eight children with relapsed high-grade malignant brain tumors. J. Neurooncol. 86 (2008) 175-181
29. Zhou R., Mazurchuk R., and Straubinger R.M. Antivasculature effects of doxorubicin-containing liposomes in an intracranial rat brain tumor model. Cancer Res. 62 (2002) 2561-2566