Two-year inhalation study of carcinogenicity and chronic toxicity of 1,4-dioxane in male rats 2-yr inhalation study of 1,4-dioxane in rats Tatsuya Kasai et al.

Inhalation Toxicology

Volumn 21, Issue 11, 2009, Pages 889-897

  Kasai, Tatsuya ^a   Kano, Hirokazu ^a   Umeda, Yumi ^a   Sasaki, Toshiaki ^a   Ikawa, Naoki ^a   Nishizawa, Tomoshi ^a   Nagano, Kasuke ^a   Arito, Heihachiro ^a   Nagashima, Hiroshi ^b   Fukushima, Shoji ^a  

^a JAPAN INDUSTRIAL SAFETY AND HEALTH ASSOCIATION   (Japan)

^b MEIJI UNIVERSITY   (Japan)

Author keywords

1,4 dioxane; Inhalation exposure; Liver; Nasal cavity; Rat; Tumors

Indexed keywords

ALANINE AMINOTRANSFERASE; ALKALINE PHOSPHATASE; ASPARTATE AMINOTRANSFERASE; DIOXANE; GAMMA GLUTAMYLTRANSFERASE;

ADENOMA; ALANINE AMINOTRANSFERASE BLOOD LEVEL; ALKALINE PHOSPHATASE BLOOD LEVEL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; ASPARTATE AMINOTRANSFERASE BLOOD LEVEL; ATROPHY; BODY WEIGHT; CARCINOGENESIS; CARCINOGENICITY; CHRONIC TOXICITY; CONTROL GROUP; CONTROLLED STUDY; ENVIRONMENTAL EXPOSURE; FIBROADENOMA; GAMMA GLUTAMYL TRANSFERASE BLOOD LEVEL; GENOTOXICITY; IN VIVO STUDY; INCIDENCE; KIDNEY CARCINOMA; LIVER CELL CARCINOMA; LIVER WEIGHT; MALE; MALIGNANT NEOPLASTIC DISEASE; MAMMARY GLAND; METAPLASIA; NONHUMAN; NOSE CARCINOMA; NOSE CAVITY; PERITONEUM MESOTHELIOMA; PRIORITY JOURNAL; RAT; SQUAMOUS CELL CARCINOMA; SURVIVAL RATE;

ANIMALS; BODY WEIGHT; CARCINOGENS; CHRONIC DISEASE; DIOXANES; DOSE-RESPONSE RELATIONSHIP, DRUG; GROWTH; INHALATION EXPOSURE; MALE; NEOPLASMS; NO-OBSERVED-ADVERSE-EFFECT LEVEL; ORGAN SIZE; PRECANCEROUS CONDITIONS; RATS; RATS, INBRED F344; SURVIVAL;

RATTUS;

EID: 70350159483     PISSN: 08958378     EISSN: 10917691     Source Type: Journal    
DOI: 10.1080/08958370802629610     Document Type: Article

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