Evaluation of human recession defects treated with coronally advanced flaps and either purified recombinant human platelet-derived growth factor-BB with beta tricalcium phosphate or connective tissue: A histologic and microcomputed tomographic examination

International Journal of Periodontics and Restorative Dentistry

Volumn 29, Issue 1, 2009, Pages 7-21

  McGuire, Michael K ^a   Scheyer, Todd ^a   Nevins, Myron ^a   Schupbach, Peter ^a  

^a University of Pennsylvania ^*  (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANGIOGENIC FACTOR; BETA-TRICALCIUM PHOSPHATE; CALCIUM PHOSPHATE; COLLAGEN; DRUG CARRIER; PLATELET DERIVED GROWTH FACTOR; PLATELET DERIVED GROWTH FACTOR BB; PLATELET-DERIVED GROWTH FACTOR BB; RECOMBINANT PROTEIN;

ARTICLE; BONE REGENERATION; CEMENTUM; CLINICAL TRIAL; CONNECTIVE TISSUE; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DRUG EFFECT; FOLLOW UP; GINGIVA DISEASE; HUMAN; JAW; MICRO-COMPUTED TOMOGRAPHY; PERIODONTAL LIGAMENT; PHYSIOLOGY; RADIOGRAPHY; RANDOMIZED CONTROLLED TRIAL; REGENERATION; TRANSPLANTATION; TREATMENT OUTCOME;

ALVEOLAR PROCESS; ANGIOGENESIS INDUCING AGENTS; BONE REGENERATION; CALCIUM PHOSPHATES; COLLAGEN; CONNECTIVE TISSUE; DENTAL CEMENTUM; DRUG CARRIERS; FOLLOW-UP STUDIES; GINGIVAL RECESSION; HUMANS; PERIODONTAL LIGAMENT; PLATELET-DERIVED GROWTH FACTOR; RECOMBINANT PROTEINS; REGENERATION; TREATMENT OUTCOME; X-RAY MICROTOMOGRAPHY;

EID: 70350153391     PISSN: 01987569     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (29)

1. Trombelli L Periodontal regeneration in gingival recession defects. Periodontol 2000 1999;19:138-150.
2. Roccuzzo M, Bunino M, Needleman I, Sanz M. Periodontal plastic surgery for treatment of localized gingival recessions: A systematic review. J Clin Periodontol 2002;29(Suppl 3):178-194.
3. Oates TW, Robinson M, Gunsolley JC. Surgical therapies for the treatment of gingival recession. A systematic review. Ann Periodontol 2003;8:303-320.
4. Cortellini P, Clauser C, Pini Prato G. Histologic assessment of new attachment following the treatment of a human buccal recession by means of a guided tissue regeneration procedure. J Periodontol 1993;64:387-391.
5. Parma-Benfenati S, Tinti C. Histologic evaluation of new attachment utilizing a titanium-reinforced barrier membrane in a mucogingival recession defect. A case report. J Periodontol 1998;69:834-839.
6. Vincenzi G, De Chiesa A, Trisi P. Guided tissue regeneration using a resorbable membrane in gingival recession-type defects: A histologic case report in humans. Int J Periodontics Restorative Dent 1998; 18: 24-33.
7. Harris RJ. Histologic evaluation of root coverage obtained with GTR in humans: A case report. Int J Periodontics Restorative Dent 2001;21:240-251.
8. Richardson CR, Maynard JG. Acellularder-mal graft: A human histologic case report. Int J Periodontics Restorative Dent 2002;22:21-29.
9. Cummings LC, Kaldahl WB, Allen EP. Histologic evaluation of autogenous connective tissue and acellular dermal matrix grafts in humans. J Periodontol 2005;76: 178-186.
10. Rasperini G, Silvestri M, Schenk RK, Nevins ML. Clinical and histologic evaluation of human gingival recession treated with a subepithelial connective tissue graft and enamel matrix derivative (Emdogain): A case report. Int J Periodontics Restorative Dent 2000;20:269-275.
11. McGuire MK, Cochran DL. Evaluation of human recession defects treated with coro-nally advanced flaps and either enamel matrix derivative or connective tissue. Part 2: Histological evaluation. J Periodontol 2003;74:1126-1135.
12. Heijl L. Periodontal regeneration with enamel matrix derivative in one human experimental defect. A case report. J Clin Periodontol 1997;24:693-696.
13. Goldstein M, Boyan BD, Cochran DL, Schwartz Z. Human histology of new attachment after root coverage using subepithelial connective tissue graft. J Clin Periodontol 2001;28:657-662.
14. Harris RJ. Successful root coverage: A human histologic evaluation of a case. Int J Periodontics Restorative Dent 1999;19: 439-447.
15. Bruno JF, Bowers GM. Histology of a human biopsy section following the placement of a subepithelial connective tissue graft. Int J Periodontics Restorative Dent 2000;20:225-231.
16. Harris RJ. Human histologic evaluation of root coverage obtained with a connective tissue with partial thickness double pedicle graft. A case report. J Periodontol 1999;70:813-821.
17. Majzoub A, Landi L, Grusovin MG, Cordioli G. Histology of connective tissue graft. A case report. J Periodontol 2001 ;72: 1607-1615.
18. Nevins M, Giannobile wv, McGuire MK, et al. Platelet-derived growth factor stimulates bone fill and rate of attachment level gain: Results of a large multicenter randomized controlled trial. J Periodontol 2005;76:2205-2215.
19. Lynch SE, Williams RC, Poison AM, et al. A combination of platelet-derived and insulin-like growth factors enhances periodontal regeneration. J Clin Periodontol 1989;16:545-558.
20. Matsuda N, Lin WL, Kumar Ml, Cho Ml, Genco RJ. Mitogenic, chemotactic, and synthetic responses of rat periodontal ligament fibroblastic cells to polypeptide growth factors in vitro. J Periodontol 1992;63:515-525.
21. Camelo M, Nevins ML, Schenk RK, Lynch SE, Nevins M. Periodontal regeneration in human Class II furcations using purified recombinant human platelet-derived growth factor-BB (rhPDGF-BB) with bone allograft. Int J Periodontics Restorative Dent 2003;23:213-225. (Pubitemid 37152372)
22. Nevins M, Camelo M, Nevins ML, Schenk RK, Lynch SE. Periodontal regeneration in humans using recombinant human platelet derived growth factor-BB (rhPDGF-BB) and allogenic bone. J Periodontol 2003;74: 1282-1292. (Pubitemid 37336738)
23. Ridgway HK, Mellonig JT, Cochran DL. Human histologic and clinical evaluation of recombinant human platelet-derived growth factor and beta-tricalcium phosphate for the treatment of periodontal intraosseous defects. Int J Periodontics Restorative Dent 2008;28:171-179.
24. McGuire MK, Scheyer ET. Comparison of recombinant human platelet-derived growth factor-BB plus beta tricalcium phosphate and a collagen membrane to subepithelial connective tissue grafting for the treatment of recession defects: A case series. Int J Periodontics Restorative Dent 2006;26:127-133.
25. Malizos KN, Papatheodorou LK. The healing potential of the periosteum molecular aspects. Injury 2005;36 Suppl 3:S13-19.
26. Emans PJ, Surtel DA, Frings EJ, Bulstra SK, Kuijer R. In vivo generation of cartilage from periosteum. Tissue Eng 2005;11: 369-377.
27. Stevens MM, Marini RP, Schaefer D, Aronson J, Langer R, Shastri VP. In vivo engineering of organs: The bone bioreac-tor. Proc Natl Acad Sci USA 2005; 102: 11450-11455.
28. Carnio J, Camargo PM, Kenney EB. Root resorption associated with a subepithelial connective tissue graft for root coverage: Clinical and histologic report of a case. Int J Periodontics Restorative Dent 2003 ;23:391-398.
29. Hokett SD, Peacock ME, Burns WT, Swiec GD, Cuenin MR External root resorption following partial-thickness connective tissue graft placement: A case report. J Periodontol 2002;73:334-339.