Liver disease: Early signs you may be missing

Journal of Family Practice

Volumn 58, Issue 10, 2009, Pages 514-521

  Ignazio, Grattagliano ^a   Ubaldi, Enzo ^a   Portincasa, Piero ^b   Palasciano, Giuseppe ^b  

^a Italian College of General Practitioners   (Italy)

^b UNIVERSITY OF BARI MEDICAL SCHOOL   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

ADEFOVIR; ALANINE AMINOTRANSFERASE; ALPHA TOCOPHEROL; ALPHA2B INTERFERON; AMIODARONE; ASPARTATE AMINOTRANSFERASE; AZATHIOPRINE; CHELATING AGENT; ENTECAVIR; FUROSEMIDE; GLITAZONE DERIVATIVE; INSULIN; INSULIN SENSITIZING AGENT; INTERFERON; KAVA EXTRACT; LAMIVUDINE; METFORMIN; NORFLOXACIN; PENICILLAMINE; PREDNISONE; REPAGLINIDE; RIBAVIRIN; SILYMARIN; SPIRONOLACTONE; SULFONYLUREA DERIVATIVE; TELBIVUDINE; TENOFOVIR; URSODEOXYCHOLIC ACID; VALPROIC ACID; ZINC;

ABDOMINAL SWELLING; ALANINE AMINOTRANSFERASE BLOOD LEVEL; ALCOHOL ABUSE; ALCOHOL CONSUMPTION; ASCITES; ASPARTATE AMINOTRANSFERASE BLOOD LEVEL; AUTOIMMUNE HEPATITIS; BACTERIAL PERITONITIS; DELTA AGENT HEPATITIS; DIABETES MELLITUS; ECHOGRAPHY; ELASTOGRAPHY; ESOPHAGUS VARICES; FATIGUE; FATTY LIVER; FEVER; FRAGILITY FRACTURE; HEMOCHROMATOSIS; HEPATIC ENCEPHALOPATHY; HEPATITIS; HEPATITIS B; HEPATITIS C; HOME CARE; HOSPITAL CARE; HUMAN; HYPERGLYCEMIA; LABORATORY TEST; LIVER BIOPSY; LIVER CIRRHOSIS; LIVER FAILURE; LIVER FIBROSIS; LIVER FUNCTION; LONG TERM CARE; MALNUTRITION; NON INSULIN DEPENDENT DIABETES MELLITUS; NONALCOHOLIC FATTY LIVER; OBESITY; OSTEOPOROSIS; PORTAL HYPERTENSION; PRIMARY BILIARY CIRRHOSIS; REVIEW; RISK FACTOR; SEPSIS; STEATOSIS; VIRUS HEPATITIS; WILSON DISEASE;

AGED; ALANINE TRANSAMINASE; ALGORITHMS; BIOPSY; DIAGNOSIS, DIFFERENTIAL; FEMALE; HUMANS; LABORATORY TECHNIQUES AND PROCEDURES; LIVER; LIVER CIRRHOSIS; MALE; MIDDLE AGED; ULTRASONOGRAPHY;

EID: 70350151381     PISSN: 00943509     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Review

References (38)

1. Heron M, Hoyert DL, Murphy SL, et al. Deaths: final data for 2006. National Vital Stat Rep. 2009;57:(14):1-135. Available at: www.cdc.gov/nchs/ data/nvsr/nvsr57/nvsr57-14.pdf. Accessed September 16, 2009.
2. Bellentani S, Tiribelli C, Saccoccio G, et al. Prevalence of chronic liver disease in the general population of northern Italy: the Dionysos Study. Hepatology. 1994;20:1442-1449. (Pubitemid 24359054)
3. Heidelbaugh JJ, Bruderly M. Cirrhosis and chronic liver failure: part I. Diagnosis and evaluation. Am Fam Physician. 2006;74:756-762.
4. Schuppan D, Afdhal NH. Liver cirrhosis. Lancet. 2008;371:838-851.
5. Giboney PT. Mildly elevated liver transaminase levels in the asymptomatic patient. Am Fam Physician. 2005;71:1105-1110.
6. Sherwood P, Lyburn I, Brown S et al. How are abnormal results for liver function tests dealt with in primary care? Audit of yield and impact. BMJ. 2001;322:276-278 (Pubitemid 32178555)
7. US Food and Drug Administration. Food. Consumer advisory: Kava-containing dietary supplements may be associated with severe liver injury. March 25, 2002. Available at: http://www.fda.gov/Food/ResourcesForYou/Consumers/ucm085482.htm. Accessed September 11, 2009.
8. Grattagliano I, Portincasa P, Palmieri VO, et al. Managing non-alcoholic fatty liver disease: recommendations for family physicians. Can Fam Physician. 2007;53:857-863. (Pubitemid 47164278)
9. Green RM, Flamm S. AGA technical review on the evaluation of liver chemistry tests. Gastroenterology. 2002;123:1367-1384.
10. Sherman M, Klein A. AASLD single-topic research conference on hepatocellular carcinoma: conference proceedings. Hepatology. 2004;40:1465-1473. (Pubitemid 39657024)
11. Pinzani M, Vizzutti F, Arena U, et al. Technology Insight: noninvasive assessment of liver fibrosis by biochemical scores and elastography. Nat Clin Pract Gastroenterol Hepatol. 2008;5:95-106. (Pubitemid 351234279)
12. Castera L, Vergniol J, Foucher J, et al. Prospective comparison of transient elastography, Fibrotest, APRI, and liver biopsy for the assessment of fibrosis in chronic hepatitis C. Gastroenterology. 2005;128:343-350. (Pubitemid 40439195)
13. Bonny C, Rayssiguier R, Ughetto S et al. Medical practices and expectations of general practitioners in relation to hepatitis C virus infection in the Auvergne region [In French]. Gastroenterol Clin Biol. 2003;27:1021-1025. (Pubitemid 37516827)
14. Infante-Rivard C, Esnaola S, Villeneuve JP. Clinical and statistical validity of conventional prognostic factors in predicting short-term survival among cirrhotics. Hepatology. 1987;7:660-664. (Pubitemid 17118516)
15. Augustin S, Muntaner L, Altamirano JT, et al. Predicting early mortality after acute variceal hemorrhage based on classification and regression tree analysis. Clin Gastroenterol Hepatol. 2009;Aug. 20 [Epub ahead of print].
16. Wiesner R, Edwards E, Freeman R, et al. Model for end-stage liver disease (MELD) and allocation of donor livers. Gastroenterology. 2003;124:91-96. (Pubitemid 36055342)
17. United Network of Organ Sharing. Resources. Meld/Peld calculator. Available at: http://www.unos.org/resources/meldPeldCalculator.asp. Accessed September 11, 2009.
18. Bini EJ, Weinshel EH, Generoso R, et al. Impact of gastroenterology consultation on the outcomes of patients admitted to the hospital with decompensated cirrhosis. Hepatology. 2001;34:1089-1095. (Pubitemid 33096580)
19. Habib A, Bond WM, Heuman DM. Long-term management of cirrhosis. Appropriate supportive care is both critical and difficult. Postgrad Med. 2001;109:101-103.
20. Flora K, Hahn M, Rosen H, et al. Milk thistle (Silybum marianum) for the therapy of liver disease. Am J Gastroenterol. 1998;93:139-143. (Pubitemid 29063954)
21. Buyse S, Durand F, Joly F. Nutritional assessment in cirrhosis [In French]. Gastroenterol Clin Biol. 2008;32:265-273.
22. Plauth M, Merli M, Kondrup J, et al. ESPEN guidelines for nutrition in liver disease and transplantation. Clin Nutr. 1997;16:43-55. (Pubitemid 27249892)
23. Collier JD, Ninkovic M, Compston JE. Guidelines on the management of osteoporosis associated with chronic liver disease. Gut. 2002;50(suppl 1):i1-i9. (Pubitemid 41185465)
24. Nishida T, Tsuji S, Tsujii M, et al. Oral glucose tolerance test predicts prognosis of patients with liver cirrhosis. Am J Gastroenterol 2006;101:70-75. (Pubitemid 43381711)
25. Garcia-Compean D, et al. Liver cirrhosis and diabetes: risk factors, pathophysiology, clinical implications and management. World J Gastroenterol. 2009;15:280-288.
26. Karnofsky Performance Scale Index. Available at: http://www.medal.org/ visitor/www%5CActive%5Cch1%5Cch1.01%5Cch1.01.01.aspx. Accessed September 11, 2009.
27. Gentilini P, Bernardi M, Bolondi L, et al. The rational use of albumin in patients with cirrhosis and ascites. A Delphi study for the attainment of a consensus on prescribing standards. Dig Liver Dis. 2004;36:539-546.
28. Kashani A, Landaverde C, Medici V, et al. Fluid retention in cirrhosis: pathophysiology and management. QJM. 2008;101:71-85. (Pubitemid 351234707)
29. Runyon BA. Management of adult patients with ascites due to cirrhosis. Hepatology. 2004;39:841-856.
30. Gines P et al. Pathophysiology, complications, and treatment of ascites. Clin Liver Dis. 1997;1:129-155.
31. Sarin SK, Lamba GS, Kumar M, et al. Comparison of endoscopic ligation and propranolol for the primary prevention of variceal bleeding. N Engl J Med 1999;340:988-993. (Pubitemid 29157630)
32. Grace ND. Diagnosis and treatment of gastrointestinal bleeding secondary to portal hypertension. American College of Gastroenterology Practice Parameters Committee. Am J Gastroenterol. 1997;92:1081-1091.
33. McCormick PA, Greenslade L, Kibbler CC, et al. A prospective randomized trial of ceftazidime versus netilmicin plus mezlocillin in the empirical therapy of presumed sepsis in cirrhotic patients. Hepatology. 1997;25:833-836. (Pubitemid 27157122)
34. Czaja AJ, Freese DK. Diagnosis and treatment of autoimmune hepatitis. Hepatology. 2002;36:479-497.
35. European Association tor the Study of the Liver. EASL Clinical Practice Guidelines: management of chronic hepatitis B. J Hepatol 2009;50:227-242.
36. Ghany MG, Strader DB, Thomas DL, et al. Diagnosis, management, and treatment of hepatitis C: an update. Hepatology. 2009;49:1335-1374.
37. Portincasa P, Grattagliano I, Palmieri VO, et al. Current pharmacological treatment of nonalcoholic fatty liver. Curr Med Chem. 2006;13:2889-2900. (Pubitemid 44509714)
38. Reuben A. Alcohol and the liver. Curr Opin Gastroenterol. 2008;24:328-338.