Identification of functional marker proteins in the mammalian growth cone

Proceedings of the National Academy of Sciences of the United States of America

Volumn 106, Issue 40, 2009, Pages 17211-17216

  Nozumi, Motohiro ^a,b   Togano, Tetsuya ^a   Takahashi Niki, Kazuko ^a   Lu, Jia ^a   Honda, Atsuko ^a,b   Taoka, Masato ^c,d   Shinkawa, Takashi ^c,d   Koga, Hisashi ^e   Takeuchi, Kosei ^a,b   Isobe, Toshiaki ^c,d   Igarashi, Michihiro ^a,b  

^a NIIGATA UNIVERSITY GRADUATE SCHOOL OF MEDICAL AND DENTAL SCIENCES   (Japan)

^b NIIGATA UNIVERSITY   (Japan)

^c TOKYO METROPOLITAN UNIVERSITY   (Japan)

^d JAPAN SCIENCE AND TECHNOLOGY AGENCY   (Japan)

^e KAZUSA DNA RESEARCH INSTITUTE   (Japan)

Author keywords

Axon guidance; GAP 43; Neuronal growth associated proteins; Proteomics; RNAi

Indexed keywords

ACTIN BINDING PROTEIN; CATENIN; COLLAPSIN RESPONSE MEDIATOR PROTEIN; DYNEIN ADENOSINE TRIPHOSPHATASE; MEMBRANE PROTEIN; MICROTUBULE ASSOCIATED PROTEIN; MYOSIN HEAVY CHAIN; NEUROMODULIN; TUBULIN;

ANIMAL CELL; ANIMAL CELL CULTURE; ARTICLE; BRAIN DEVELOPMENT; BRAIN GROWTH; EMBRYO; FOREBRAIN; GROWTH CONE; HEAVY CHAIN; IMMUNOHISTOCHEMISTRY; MAMMAL; NERVE FIBER GROWTH; NONHUMAN; NUCLEOTIDE SEQUENCE; PERINATAL PERIOD; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEOMICS; QUANTITATIVE ANALYSIS; RAT; RNA INTERFERENCE; SYNAPTOSOME;

ADAPTOR PROTEINS, SIGNAL TRANSDUCING; ANIMALS; ANIMALS, NEWBORN; BIOLOGICAL MARKERS; CATENINS; CELLS, CULTURED; CHROMATOGRAPHY, LIQUID; GREEN FLUORESCENT PROTEINS; GROWTH CONES; IMMUNOBLOTTING; IMMUNOHISTOCHEMISTRY; MASS SPECTROMETRY; MICROSCOPY, FLUORESCENCE; MICROTUBULE-ASSOCIATED PROTEINS; NERVE GROWTH FACTORS; NERVE TISSUE PROTEINS; NEURONS; PROSENCEPHALON; PROTEOME; PROTEOMICS; RATS; RATS, TRANSGENIC; RNA INTERFERENCE; TIME FACTORS;

MAMMALIA; RATTUS;

EID: 70350125098     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.0904092106     Document Type: Article

References (47)

1. Chilton JK (2006) Molecular mechanisms of axon guidance. Dev Biol 292:13-24.
2. Gomez TM, Zheng JQ (2006) Themolecular basis forcalcium- dependentaxonpathfinding. Nat Rev Neurosci 7:115-125.
3. Gogolla N, Galimbeti I, Caroni P (2007) Structural plasticity of axon terminals in the adult. Curr Opin Neurobiol 17:516-524.
4. Zhou F-Q, Snider WD (2006) Intracellular control of developmental and regenerative axon growth. Philos Trans R Soc London Ser B 361:1575-1592. (Pubitemid 44450212)
5. Bean AJ (2006) Protein Trafficking in Neurons (Academic, Burlington, MA).
6. Igarashi M, Ohko K (2009) Proteins involved in the presynaptic functions. Handbook of Neurochemistry and Molecular Neurobiology: Neural Signaling Mechanisms, ed Mikoshiba K (Springer, New York), pp 47-62.
7. Fishman MC (1996) GAP-43: Putting constraints on neuronal plasticity. Perspect Dev Neurobiol 4:193-198.
8. Liao L, McClatchy DB, Yates JR, 3rd (2009) Shotgun proteomics in neuroscience. Neuron 63:12-26.
9. Liao L, Park SK, Xu T, Vanderklish P, Yates JR, 3rd (2008) Quantitative proteomic analysis of primary neurons reveals diverse changes in synaptic protein content in fmr1 knockout mice. Proc Natl Acad Sci USA 105:15281-15286.
10. Emes RD, et al. (2008) Evolutionary expansion and anatomical specialization of synapse proteome complexity. Nat Neurosci 11:799-806.
11. Pertz OC, et al. (2008) Spatial mapping of the neurite and soma proteomes reveals a functional Cdc42/Rac regulatory network. Proc Natl Acad Sci USA 105:1931-1936.
12. Pfenninger KH, Ellis L, Johnson MP, Friedman LB, Somlo S (1983) Nerve growth cones isolated from fetal rat brain: I. Subcellular fractionation and characterization. Cell 35:573-584. (Pubitemid 14202935)
13. Ellis L, Wallis I, Abreu E, Pfenninger KH (1985) Nerve growth cones isolated from fetal rat brain. IV. Preparation of a membrane subfraction and identification of a membrane glycoprotein expressed on sprouting neurons. J Cell Biol 101:1977-1989. (Pubitemid 16192170)
14. Gordon-Weeks PR (1987) The cytoskeletons of isolated, neuronal growth cones. Neuroscience 21:977-989. (Pubitemid 17106400)
15. Mawuenyega KG, et al. (2003) Large-scale identification of Caenorhabditis elegans proteins by multidimensional liquid chromatography-tandem mass spectrometry. J Proteome Res 2:23-35.
16. Shinkawa T, et al. (2005) STEM: A software tool for large-scale proteomic data analyses. J Proteome Res 4:1826-1831. (Pubitemid 41472075)
17. Pal CW, Flunn KC, Bamburg JR (2008) Actin-binding proteins take the reins in growth cones. Nat Rev Neurosci 9:136-147.
18. Liu H, Sadygov RG, Yates JR, 3rd (2004) A model for random sampling and estimation of relative protein abundance in shotgun proteomics. Anal Chem 76:4193-4201.
19. Lin AC, Holt CE (2007) Local translation and directional steering in axons.EMBOJ 26:3729-3736.
20. Fukata Y, et al. (2002) CRMP-2 binds to tubulin heterodimers to promote microtubule assembly. Nat Cell Biol 4:583-591. (Pubitemid 34905597)
21. Vega IE, Hsu SC (2003) The septin protein Nedd5 associates with both the exocyst complex and microtubules and disruption of its GTPase activity promotes aberrant neurite sprouting in PC12 cells. NeuroReport 14:31-37.
22. Wills Z, et al. (2002)ADrosophilahomologof cyclase-associated proteins collaborates with the Abl tyrosine kinase to control midline axon pathfinding. Neuron 36:611-622. (Pubitemid 35346755)
23. Schenck A, et al. (2003) CYFIP/Sra-1 controls neuronal connectivity in Drosophila and links the Rac1 GTPase pathway to the fragile X protein. Neuron 38:887-898. (Pubitemid 36782381)
24. Osen-Sand A, et al. (1993) Inhibition of axonal growth by SNAP-25 antisense oligonucleotides in vitro and in vivo. Nature 364:445-448. (Pubitemid 23263215)
25. Igarashi M, Strittmatter SM, Vartanian T, Fishman MC (1993) Mediation by G proteins of signals that cause collapse of growth cones. Science 259:77-79. (Pubitemid 23036089)
26. Hasegawa Y, et al. (2004) Promotion of axon regeneration by myelin-associated glycoproteinandNogothrough divergent signalsdownstreamof Gi/G. J Neurosci 24:6826-6832. (Pubitemid 38993905)
27. Toyofuku T, et al. (2005) FARP2 triggers signals for Sema3A-mediated axonal repulsion. Nat Neurosci 8:1712-1719. (Pubitemid 41683199)
28. Igarashi M, et al. (1996) Growth cone collapse and inhibition of neurite growth by Botulinum neurotoxin C1:At-SNARE is involved in axonal growth. J Cell Biol 134:205-215. (Pubitemid 26231531)
29. Darios F, Davletov B (2006) Omega-3 and omega-6 fatty acids stimulate cell membrane expansion by acting on syntaxin 3. Nature 440:813-817.
30. Chen Z-L, Yu W-m, Strickland S (2007) Peripheral regeneration. Annu Rev Neurosci 30:209-233.
31. Grzywa EL, Lee AC, Lee GU, Suter DM (2006) High-resolution analysis of neuronal growth cone morphology by comparative atomic force and optical microscopy. J Neurobiol 6:1529-1543.
32. Datta PK, Chytil A,Gorska AE,Moses HL (1998) Identification ofSTRAP,anovelWDdomain protein in transforming growth factor-βsignaling. J Biol Chem 273:34671-34674. (Pubitemid 29028152)
33. Yoshiura K, et al. (1998) Characterization of a novel gene disrupted by a balanced chromosomal translocation t(2;19)(q11.2;q13.3) in a family with cleft lip and palate. Genomics 54:231-240. (Pubitemid 28553632)
34. Steiner P, et al. (2004) Reticulon 1-C/neuroendocrine-specific protein-C interacts with SNARE proteins. J Neurochem 89:569-580. (Pubitemid 38534143)
35. Charron F, Tessier-Lavigne M (2005) Novel brain wiring functions for classical morphogens: A role as graded positional cues in axon guidance. Development 132:2251-2262. (Pubitemid 40872796)
36. Deuel TA, et al. (2006) Genetic interactions between doublecortin and doublecortin-like kinase in neuronal migration and axon outgrowth. Neuron 49:41-53. (Pubitemid 43017184)
37. Ye B, et al. (2007) Growing dendrites and axons differ in their reliance on the secretory pathway. Cell 130:717-729. (Pubitemid 47268054)
38. David S, Lacroix S (2003) Molecular approaches to spinal cord repair. Annu Rev Neurosci 26:411-440. (Pubitemid 37064940)
39. Stefansson H, et al. (2008) Large recurrent microdeletions associated with schizophrenia. Nature 455:232-236.
40. Lewis DA, Sweet RA (2009) Schizophrenia from a neural circuitry perspective: Advancing toward rational pharmacological therapies. J Clin Invest 119:706-716.
41. Phelan P, Gordon-Weeks PR (1997) Isolation of synaptosomes, growth cones, and their subcellular components. Neurochemistry: A Practical Approach, eds Turner AJ, Bachelard HS (Oxford Univ Press, New York), 2nd Ed, pp 1-38.
42. Igarashi M, Tagaya M, Komiya Y (1997) The SNARE complex in growth cones: Molecular aspects of the axon terminal development. J Neurosci 17:1460-1470.
43. Natsume T, et al. (2002) A direct nanoflow liquid chromatography-tandem mass spectrometry system for interaction proteomics. Anal Chem 74:4725-4733. (Pubitemid 35051730)
44. Isobe T,Yamauchi Y,Taoka M,Takahashi N (2003) Automated two-dimensional LC-MS/MS for large-scale protein analysis. Proteins and Proteomics, ed Simpson RJ (Cold Spring Harbor Lab Press, Cold Spring Harbor, NY), pp 869-876.
45. Lu J, Nozumi M, Fuji H, Igarashi M (2008) A novel method for RNA interference in the neuron using enhanced green fluorescence protein (EGFP)-transgenic rat. Neurosci Res 61:219-224.
46. Petrie A (1987) Lecture Notes of Medical Statistics (Blackwell, Oxford, UK), 2nd Ed.
47. Taoka M, et al. (2004) Only a small subset of the horizontally transferred chromosomal genes in Escherichia coli are translated into proteins. Mol Cell Proteomics 3:780-787. (Pubitemid 39199579)