Does palliative sedation always relieve symptoms?

Journal of Palliative Medicine

Volumn 12, Issue 10, 2009, Pages 875-877

  Davis, Mellar P ^a,b  

^a CLEVELAND CLINIC LERNER COLLEGE OF MEDICINE   (United States)

^b TAUSSIG CANCER INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BENZODIAZEPINE; FENTANYL; MIDAZOLAM; PHENOTHIAZINE; PROPOFOL; HYPNOTIC SEDATIVE AGENT;

ANESTHESIST; ARTICLE; AWARENESS; CENTRAL NERVOUS SYSTEM; ELECTROENCEPHALOGRAM; FEAR; HELPLESSNESS; HEMODYNAMICS; HUMAN; PALLIATIVE THERAPY; SEDATION; SIGNAL TRANSDUCTION; ANESTHESIA; CONSCIOUS SEDATION; PAIN; PROCEDURES;

ANESTHESIA; CONSCIOUS SEDATION; HUMANS; HYPNOTICS AND SEDATIVES; PAIN; PALLIATIVE CARE;

EID: 70350124032     PISSN: 10966218     EISSN: None     Source Type: Journal    
DOI: 10.1089/jpm.2009.0148     Document Type: Article

References (27)

1. Kohara H, Ueoka H, Takeyama H, Murakami T, Morita T: Sedation for terminally ill patients with cancer with uncontrollable physical distress. J Palliat Med 2005;8:20-25. (Pubitemid 40144248)
2. Rietjens J, van Delden J, Onwuteaka-Philipsen B, Buiting H, van der Maas P, van der Heide A: Continuous deep sedation for patients nearing death in the Netherlands: Descriptive study. BMJ 2008;336:810-813.
3. Elsayem A, Boohene J, Munsell MF, Munsell MF, Calderon B, Hung F, Bruera E: Use of palliative sedation for intractable symptoms in the palliative care unit of a comprehensive cancer center. Support Care Cancer 2008;17:53-59
4. de Graeff A, Dean M: Palliative sedation therapy in the last weeks of life: A literature review and recommendations for standards. J Palliat Med 2007;10:67-85.
5. Ghoneim MM: Incidence of and risk factors for awareness during anaesthesia. Best Pract Res Clin Anaesthesiol 2007;21: 327-343.
6. Ranta SO, Laurila R, Saario J, Ali-Melkkila T, Hynynen M: Awareness with recall during general anesthesia: incidence and risk factors. Anesth Analg 1998;86:1084-1089. (Pubitemid 28198885)
7. Samuelsson P, Brudin L, Sandin RH: Late psychological symptoms after awareness among consecutively included surgical patients. Anesthesiology 2007;106:26-32.
8. Schwender D, Kunze-Kronawitter H, Dietrich P, Klasing S, Forst H, Madler C: Conscious awareness during general anaesthesia: Patients' perceptions, emotions, cognition and reactions. Br J Anaesth 1998;80:133-139.
9. Moerman N, Bonke B, Oosting J: Awareness and recall during general anesthesia. Facts and feelings, Anesthesiology 1993;79:454-464.
10. Sebel PS, Bowdle TA, Ghoneim MM, Rampil IJ, Padilla RE, Gan TJ, Domino KB: The incidence of awareness during anesthesia: A multicenter United States study. Anesth Analg 2004;99:833-839.
11. Sigalovsky N: Awareness under general anesthesia. AANA J 2003;71:373-379.
12. Ghoneim MM, Block RI, Haffarnan M, Mathews MJ: Awareness during anesthesia: Risk factors, causes and sequelae. A review of reported cases in the literature. Anesth Analg 2009;108:527-535.
13. Hasen KV, Samartzis D, Casas LA, Mustoe TA: An outcome study comparing intravenous sedation with midazolam= fentanyl (conscious sedation) versus propofol infusion (deep sedation) for aesthetic surgery. Plast Reconstr Surg 2003;112: 1683-1689; discussion 1690-1691.
14. Moscona RA, Ramon I, Ben-David B, Isserles S: A comparison of sedation techniques for outpatient rhinoplasty: Midazolam versus midazolam plus ketamine. Plast Reconstr Surg 1995;96:1066-1074.
15. Guignard B: Monitoring analgesia. Best Pract Res Clin Anaesthesiol 2006;20:161-180.
16. Halliburton JR. Awareness during general anesthesia: new technology for an old problem. CRNA 1998;9:39-43.
17. Sandler NA, Hodges J, Sabino M: Assessment of recovery in patients undergoing intravenous conscious sedation using Bispectral analysis. J Oral Maxillofac Surg 2001;59:603-611; discussion 11-12.
18. Adam N, Sebel PS: BIS monitoring: Awareness and catastrophic events. Semin Cardiothorac Vasc Anesth 2004;8:9-12.
19. Singh H: Bispectral index (BIS) monitoring during propofolinduced sedation and anaesthesia. Eur J Anaesthesiol 1999; 16:31-36.
20. Pomfrett CJ: Heart rate variability, BIS and 'depth of anaesthesia'. Br J Anaesth 1999;82:659-662.
21. Mourisse J, Lerou J, Struys M, Zwarts M, Booij L: Multi-level approach to anaesthetic effects produced by sevoflurane or propofol in humans: 1. BIS and blink reflex. Br J Anaesth 2007;98:737-745.
22. Bruhn J, Myles PS, Sneyd R, Struys MM: Depth of anaesthesia monitoring: What's available, what's validated and what's next? Br J Anaesth 2006;97:85-94.
23. Myles PS, Leslie K, McNeil J, Forbes A, Chan MT: Bispectral index monitoring to prevent awareness during anaesthesia: The B-Aware randomised controlled trial. Lancet 2004;363: 1757-1763.
24. Doi M, Morita K, Mantzaridis H, Sato S, Kenny GN: Prediction of responses to various stimuli during sedation: A comparison of three EEG variables. Intensive Care Med 2005;31:41-47.
25. Morita T, Chinone Y, Ikenaga M, Miyoshi M, Nakaho T, Nishitateno K, Sakonji M, Shima Y, Suenaga K, Takigawa C, Kohara H, Tani K, Kawamura Y, Matsubara T, Watanabe A, Yagi Y, Sasaki T, Higuchi A, Kimura H, Abo H, Ozawa T, Kizawa Y, Uchitomi Y; Japan Pain, Palliative Medicine, Rehabilitation, and Psycho-Oncology Study Group: Efficacy and safety of palliative sedation therapy: A multicenter, prospective, observational study conducted on specialized palliative care units in Japan. J Pain Symptom Manage 2005;30:320-328. (Pubitemid 41527118)
26. Ramsay MA, Savege TM, Simpson BR, Goodwin R: Controlled sedation with alphaxalone-alphadolone. Br Med J 1974;2:656-659.
27. Riker RR, Picard JT, Fraser GL: Prospective evaluation of the Sedation-Agitation Scale for adult critically ill patients. Crit Care Med 1999;27:1325-1329.