Naloxone, but Not Flupenthixol, Disrupts the Development of Conditioned Ejaculatory Preference in the Male Rat

Behavioral Neuroscience

Volumn 123, Issue 5, 2009, Pages 992-999

  Ismail, Nafissa ^a   Girard Bériault, Fabienne ^a   Nakanishi, Satoru ^a   Pfaus, James G ^a  

^a and Applied Physiology   (Canada)

Author keywords

dopamine; flupenthixol; naloxone; opioids; partner preference

Indexed keywords

DOPAMINE; FLUPENTIXOL; NALOXONE; OPIATE; SODIUM CHLORIDE;

ANIMAL EXPERIMENT; ARTICLE; CONDITIONING; CONTROLLED STUDY; DOPAMINERGIC SYSTEM; DOPAMINERGIC TRANSMISSION; EJACULATION; FEMALE; MALE; MATE CHOICE; NONHUMAN; ODOR; OPEN FIELD TEST; RAT; SEXUAL BEHAVIOR; SEXUAL INTERCOURSE;

ANALYSIS OF VARIANCE; ANIMALS; ASSOCIATION LEARNING; CHOICE BEHAVIOR; COPULATION; DOPAMINE; DOPAMINE ANTAGONISTS; EJACULATION; FEMALE; FLUPENTHIXOL; INJECTIONS, SUBCUTANEOUS; MALE; MATING PREFERENCE, ANIMAL; NALOXONE; NARCOTIC ANTAGONISTS; ODORS; OPIOID PEPTIDES; RATS; RATS, LONG-EVANS; RECEPTORS, DOPAMINE; RECEPTORS, OPIOID; RECOGNITION (PSYCHOLOGY); SMELL;

EID: 70350109379     PISSN: 07357044     EISSN: None     Source Type: Journal    
DOI: 10.1037/a0017096     Document Type: Article

References (57)

1. Ågmo A. Lack of opioid or dopaminergic effects on unconditioned sexual incentive motivation in male rats. Behavioral Neuroscience 117 (2003) 55-68
2. Ågmo A., and Berenfeld R. Reinforcing properties of ejaculation in the male rat: Role of opioids and dopamine. Behavioral Neuroscience 104 (1990) 177-182
3. Arletti R., Bazzani C., Castelli M., and Bertolini A. Oxytocin improves male copulatory performance in rats. Hormones and Behavior 19 (1985) 14-20
4. Baskerville T.A., and Douglas A.J. Interactions between dopamine and oxytocin in the control of male sexual behaviour. Progress in Brain Research 170 (2008) 277-290
5. Blackburn J.R., Pfaus J.G., and Phillips A.G. Dopamine functions in appetitive and defensive behaviours. Progress in Neurobiology 39 (1992) 247-279
6. Cabilio, S. (1996). Behavioral observation program [Unpublished computer software]. Concordia University, Montreal.
7. Cantor J.M., Binik Y.M., and Pfaus J.G. Chronic fluoxetine inhibits sexual behavior in the male rat: Reversal with oxytocin. Psychopharmacology (Berl) 144 (1999) 355-362
8. Clarke S., Zimmer A., Zimmer A.M., Hill R.G., and Kitchen I. Region selective up-regulation of mu-, delta- and kappa-opioid receptors but not opioid receptor-like 1 receptors in the brains of enkephalin and dynorphin knockout mice. Neuroscience 122 (2003) 479-489
9. Coolen L.M., Fitzgerald M.E., Yu L., and Lehman M.N. Activation of mu opioid receptors in the medial preoptic area following copulation in male rats. Neuroscience 124 (2004) 11-21
10. Coria-Avila G.A., Gavrila A.M., Boulard B., Charron N., Stanley G., and Pfaus J.G. Neurochemical basis of conditioned partner preference in the female rat: II. Disruption by flupenthixol. Behavioral Neuroscience 122 (2008) 396-406
11. Coria-Avila G.A., Ouimet A.J., Pacheco P., Manzo J., and Pfaus J.G. Olfactory conditioned partner preference in the female rats. Behavioral Neuroscience 119 (2005) 716-725
12. Coria-Avila G.A., Solomon C.E., Vargas E.B., Lemme I., Ryan R., Ménard S., and Pfaus J.G. Neurochemical basis of conditioned partner preference in the female rat: I. Disruption by naloxone. Behavioral Neuroscience 122 (2008) 385-395
13. Damsma G., Pfaus J.G., Wenkstern D., Phillips A.G., and Fibiger H.C. Sexual behavior increases dopamine transmission in the nucleus accumbens and striatum of male rats: Comparison with novelty and locomotion. Behavioral Neuroscience 106 (1992) 181-191
14. de Jong T.R., Veening J.G., Olivier B., and Waldinger M.D. Oxytocin involvement in SSRI-induced delayed ejaculation: A review of the animal studies. Journal of Sexual Medicine 4 (2007) 14-28
15. Erskine M.S., Kornberg E., and Cherry J.A. Paced copulation in rats: Effects of intromission frequency and duration on luteal activation and estrus length. Physiology & Behavior 45 (1989) 33-39
16. Fiorino D.F., Coury A., and Phillips A.G. Dynamic changes in nucleus accumbens dopamine efflux during the Coolidge effect in male rats. Journal of Neuroscience 17 (1997) 4849-4855
17. Fiorino D.F., and Phillips A.G. Facilitation of sexual behavior and enhanced dopamine efflux in the nucleus accumbens of male rats after d-amphetamine-induced behavioral sensitization. Psychopharmacology 19 (1999) 456-463
18. García-Horsman S.P., Ågmo A., and Paredes R.G. Infusions of naloxone into the medial preoptic area, ventromedial nucleus of the hypothalamus, and amygdala block conditioned place preference induced by paced mating behavior. Hormones and Behavior 54 (2008) 709-716
19. Garcia Horsman P., and Paredes R.G. Dopamine antagonists do not block conditioned place preference induced by paced mating behavior in female rats. Behavioral Neuroscience 118 (2004) 356-364
20. Gelez, H., Coria-Avila, G. A., Rajabi, H., & Pfaus, J. G. A neutral odor previously paired with copulation enhances dopamine release in the nucleus accumbens of male rats. Manuscript in preparation.
21. Gelez H., Coria-Avila G.A., Woehrling D., Rajabi H., and Pfaus J.G. A neutral odor previously paired with copulation enhances dopamine release in the nucleus accumbens of male rats. Ninth Annual Meeting of the Society for Behavioral Neuroendocrinology (June, 2005) Austin, TX
22. González-Mariscal G., Gómora P., and Bayer C. Participation of opiatergic, GABAergic, and serotonergic systems in the expression of copulatory analgesia in male rats. Pharmacology Biochemistry and Behavior 49 (1994) 303-307
23. Hardy D.F., and DeBold J.F. Effects of coital stimulation upon behavior of the female rat. Journal of Comparative Physiology and Psychology 78 (1972) 400-408
24. Ismail N., Gelez H., Lachapelle I., and Pfaus J.G. Pacing conditions contribute to the conditioned ejaculatory preference for a familiar female in the male rat. Physiology & Behavior 96 (2008) 201-208
25. Jenkins W.J., and Becker J.B. Dynamic increases in dopamine during paced copulation in the female rat. European Journal of Neuroscience 18 (2003) 1997-2001
26. Kippin T.E., and Pfaus J.G. The development of olfactory conditioned ejaculatory preferences in the male rat: I. Nature of the unconditioned stimulus. Physiology & Behavior 73 (2001) 457-469
27. Kippin T.E., Samaha A.N., Sotinopoulos V., and Pfaus J.G. The development of olfactory conditioned ejaculatory preferences in the male rat: II. Parametric manipulation of conditioning session number and duration. Physiology & Behavior 73 (2001) 471-485
28. Kippin T.E., Talianakis S., Schattmann L., Bartholomew S., and Pfaus J.G. Olfactory conditioning of sexual behavior in the male rat (Rattus norvegicus). Journal of Comparative Psychology 112 (1998) 389-399
29. Liu Y., and Wang Z.X. Nucleus accumbens oxytocin and dopamine interact to regulate pair bond formation in female prairie voles. Neuroscience 121 (2003) 537-544
30. López H.H., and Ettenberg A. Haloperidol challenge during copulation prevents subsequent increase in male sexual motivation. Pharmacology Biochemistry and Behavior 67 (2000) 387-393
31. Lorrain D.S., Riolo J.V., Matuszewich L., and Hull E.M. Lateral hypothalamic serotonin inhibits nucleus accumbens dopamine: Implications for sexual satiety. Journal of Neuroscience 19 (1999) 7648-7652
32. Mas M., Gonzalez-Mora J.L., Louilot A., Sole C., and Guadalupe T. Increased dopamine release in the nucleus accumbens of copulating male rats as evidenced by in vivo voltammetry. Neuroscience Letters 110 (1990) 303-308
33. Mehrara B.J., and Baum M.J. Naloxone disrupts the expression but not the acquisition by male rats of a conditioned place preference response for an oestrous female. Psychopharmacology 110 (1990) 118-125
34. Miller R.L., and Baum M.J. Naloxone inhibits mating and conditioned place preference for an estrous female in male rats soon after castration. Pharmacology Biochemistry and Behavior 26 (1987) 781-789
35. Mirenowicz J., and Schultz W. Importance of unpredictability for reward responses in primate dopamine. Journal of Neurophysiology 72 (1994) 1024-1027
36. Mitchell J.B., and Gratton A. Opioid modulation and sensitization of dopamine release elicited by sexually relevant stimuli: A high speed chronoamperometric study in freely behaving rats. Brain Research 551 (1991) 20-27
37. Paredes R.G., and Ågmo A. Has dopamine a physiological role in the control of sexual behavior? A critical review of the evidence. Progress in Neurobiology 73 (2004) 179-226
38. Paredes R.G., and Vasquez B. What do female rats like about sex? Paced mating. Behavioural Brain Research 105 (1999) 117-127
39. Paterson S., Robson L., and Kosterlitz H. Classification of opioid receptors. British Medical Bulletin 39 (1983) 31-36
40. Pehek E.A., Warner R.K., Bazzett T.J., Bitran D., Band L.C., Eaton R.C., and Hull E.M. Microinjection of cis-flupenthixol, a dopamine antagonist, into the medial preoptic impairs sexual behavior of male rats. Brain Research 443 (1988) 70-76
41. Pfaus J.G., Damsma G., Nomikos G.G., Wenkstern D.G., Blaha C.D., Phillips A.G., and Fibiger H.C. Sexual behavior enhances central dopamine transmission in the male rat. Brain Research 530 (1990) 345-348
42. Pfaus J.G., and Gorzalka B.B. Selective activation of opioid receptors differentiation affects lordosis behavior in female rats. Peptides 8 (1987) 309-317
43. Pfaus J.G., and Phillips A.G. Role of dopamine in anticipatory and consummatory aspects of sexual behavior in the male rat. Behavioral Neuroscience 105 (1991) 727-743
44. Pfaus J.G., and Wilkins M.F. A novel environment disrupts copulation in sexually naïve but not experienced male rats: Reversal with naloxone. Physiology & Behavior 57 (1995) 1045-1049
45. Rampin O., Jerome N., and Suaudeau C. Proerectile effects of apomorphine in mice. Life Sciences 72 (2003) 2329-2336
46. Reinoso-Barbero F., and de Andres I. Effects of opioid microinjections in the nucleus of the solitary tract on the sleep-wakefulness cycle states in cats. Anesthesiology 82 (1995) 144-152
47. Richardson N.R., and Gratton A. Changes in nucleus accumbens dopamine transmission associated with fixed- and variable-time schedule-induced feeding. European Journal of Neuroscience 27 (2008) 2714-2723
48. Sachs B.D., and Barfield R.J. Temporal patterning of sexual behavior in the male rat. Journal of Comparative Physiological Psychology 73 (1970) 359-364
49. Sachs B.D., and Meisel R.L. The physiology of male sexual behavior. In: Knobil E., and Neill J. (Eds). The physiology of reproduction (1988), Raven Press, New York 1393-1485
50. Schultz W. Predictive reward signal of dopamine neurons. Journal of Neurophysiology 80 (1998) 1-27
51. Schultz W., and Dickinson A. Neuronal coding of prediction errors. Annual Review of Neuroscience 23 (2000) 473-500
52. Szechtman H., Hershkowitz M., and Simantov R. Sexual behavior decreases pain sensitivity and stimulated endogenous opioids in male rats. European Journal Pharmacology 70 (1981) 279-285
53. Warner R.K., Thompson J.T., Markowski V.P., Loucks J.A., Bazzett T.J., Eaton R.C., and Hull E.M. Microinjection of the dopamine antagonist cis-flupenthixol into the mPOA impairs copulation, penile reflexes and sexual motivation in male rats. Brain Research 540 (1991) 177-182
54. Whipple B., and Komisaruk B.R. Elevation of pain threshold by vaginal stimulation in women. Pain 21 (1985) 357-367
55. Wigger A., and Neumann I.D. Endogenous opioid regulation of stress-induced oxytocin release within the hypothalamic paraventricular nucleus is reversed in late pregnancy: A microdialysis study. Neuroscience 112 (2002) 121-129
56. Young L.J., Lim M.M., Gingrich B., and Insel T.R. Cellular mechanisms of social attachment. Hormones and Behavior 40 (2001) 133-138
57. Young L.J., and Wang Z. The neurobiology of pair bonding. Nature Neuroscience 7 (2004) 1048-1054