Early Helicobacter pylori Eradication Decreases Risk of Gastric Cancer in Patients With Peptic Ulcer Disease

Gastroenterology

Volumn 137, Issue 5, 2009, Pages

  Wu, Chun Ying ^a,b,c   Kuo, Ken N ^d   Wu, Ming Shiang ^e   Chen, Yi Ju ^a,c   Wang, Chang Bi ^a   Lin, Jaw Town ^e,f  

^a TAICHUNG VETERANS GENERAL HOSPITAL   (Taiwan)

^b CHINA MEDICAL UNIVERSITY   (Taiwan)

^c NATIONAL YANG MING UNIVERSITY   (Taiwan)

^d NATIONAL HEALTH RESEARCH INSTITUTES   (Taiwan)

^e NATIONAL TAIWAN UNIVERSITY HOSPITAL   (Taiwan)

^f I SHOU UNIVERSITY   (Taiwan)

Author keywords

[No Author keywords available]

Indexed keywords

ACETYLSALICYLIC ACID; AMOXICILLIN; BISMUTH; CLARITHROMYCIN; CYCLOOXYGENASE 2 INHIBITOR; HISTAMINE H2 RECEPTOR ANTAGONIST; METRONIDAZOLE; NONSTEROID ANTIINFLAMMATORY AGENT; PROTON PUMP INHIBITOR; TETRACYCLINE;

ADULT; AGED; ARTICLE; CANCER INCIDENCE; CANCER RISK; CONTROLLED STUDY; DRUG MEGADOSE; DUODENUM ULCER; ERADICATION THERAPY; FEMALE; HAZARD RATIO; HELICOBACTER INFECTION; HELICOBACTER PYLORI; HOSPITALIZATION; HUMAN; LOW DRUG DOSE; MAJOR CLINICAL STUDY; MALE; PEPTIC ULCER; PRIORITY JOURNAL; STANDARDIZED INCIDENCE RATIO; STOMACH CANCER; STOMACH ULCER;

ADULT; AGED; AGED, 80 AND OVER; ANTI-BACTERIAL AGENTS; ANTI-ULCER AGENTS; COHORT STUDIES; DATABASES, FACTUAL; DRUG ADMINISTRATION SCHEDULE; DRUG THERAPY, COMBINATION; FEMALE; HELICOBACTER INFECTIONS; HELICOBACTER PYLORI; HUMANS; INCIDENCE; MALE; MIDDLE AGED; PEPTIC ULCER; RETROSPECTIVE STUDIES; STOMACH NEOPLASMS; TAIWAN; YOUNG ADULT;

EID: 70350102177     PISSN: 00165085     EISSN: None     Source Type: Journal    
DOI: 10.1053/j.gastro.2009.07.060     Document Type: Article

References (26)

1. Fox J.G., and Wang T.C. Inflammation, atrophy, and gastric cancer. J Clin Invest 117 (2007) 60-69
2. Wu M.S., Chen C.J., and Lin J.T. Host-environment interactions: their impact on progression from gastric inflammation to carcinogenesis and on development of new approaches to prevent and treat gastric cancer. Cancer Epidemiol Biomarkers Prev 14 (2005) 1878-1882
3. Fock K.M., Talley N., Moayyedi P., et al. Asia-Pacific consensus guidelines on gastric cancer prevention. J Gastroenterol Hepatol 23 (2008) 351-365
4. Talley N.J., Fock K.M., and Moayyedi P. Gastric Cancer Consensus conference recommends Helicobacter pylori screening and treatment in asymptomatic persons from high-risk populations to prevent gastric cancer. Am J Gastroenterol 103 (2008) 510-514
5. Hunt R.H. Will eradication of Helicobacter pylori infection influence the risk of gastric cancer?. Am J Med 117 (2004) S86-S91
6. Honda S., Fujioka T., Tokieda M., et al. Development of Helicobacter pylori-induced gastric carcinoma in Mongolian gerbils. Cancer Res 58 (1998) 4255-4259
7. Watanabe T., Tada M., Nagai H., et al. Helicobacter pylori infection induces gastric cancer in Mongolian gerbils. Gastroenterology 115 (1998) 642-648
8. Sugiyama A., Maruta F., Ikeno T., et al. Helicobacter pylori infection enhances N-methyl-N-nitrosourea-induced stomach carcinogenesis in the Mongolian gerbil. Cancer Res 58 (1998) 2067-2069
9. Nozaki K., Shimizu N., Ikehara Y., et al. Effect of early eradication on Helicobacter pylori-related gastric carcinogenesis in Mongolian gerbils. Cancer Sci 94 (2003) 235-239
10. Lee C.W., Rickman B., Rogers A.B., et al. Helicobacter pylori eradication prevents progression of gastric cancer in hypergastrinemic INS-GAS mice. Cancer Res 68 (2008) 3540-3548
11. Uemura N., Okamoto S., Yamamoto S., et al. Helicobacter pylori infection and the development of gastric cancer. N Engl J Med 345 (2001) 784-789
12. Wong B.C., Lam S.K., Wong W.M., et al. Helicobacter pylori eradication to prevent gastric cancer in a high-risk region of China: a randomized controlled trial. JAMA 291 (2004) 187-194
13. You W.C., Brown L.M., Zhang L., et al. Randomized double-blind factorial trial of three treatments to reduce the prevalence of precancerous gastric lesions. J Natl Cancer Inst 98 (2006) 974-983
14. Zhou L.Y., Lin S.R., Ding S.G., et al. The changing trends of the incidence of gastric cancer after Helicobacter pylori eradication in Shandong area. Chin J Dig Dis 6 (2005) 114-115
15. Leung W.K., Lin S.R., Ching J.Y., et al. Factors predicting progression of gastric intestinal metaplasia: results of a randomised trial on Helicobacter pylori eradication. Gut 53 (2004) 1244-1249
16. Mera R., Fontham E.T., Bravo L.E., et al. Long-term follow-up of patients treated for Helicobacter pylori infection. Gut 54 (2005) 1536-1540
17. Fuccio L., Zagari R.M., Minardi M.E., et al. Systematic review: Helicobacter pylori eradication for the prevention of gastric cancer. Aliment Pharmacol Ther 25 (2007) 133-141
18. Wang C., Yuan Y., and Hunt R.H. The association between Helicobacter pylori infection and early gastric cancer: a meta-analysis. Am J Gastroenterol 102 (2007) 1789-1798
19. Wu C., Wu C., Wu M., et al. Decreased hospitalization for peptic ulcer disease in Taiwan after proton pump inhibitor therapy and Helicobacter pylori eradication. Clin Gastroenterol Hepatol 7 (2009) 427-431
20. Hansson L.E., Nyren O., Hsing A.W., et al. The risk of stomach cancer in patients with gastric or duodenal ulcer disease. N Engl J Med 335 (1996) 242-249
21. Fukase K., Kato M., Kikuchi S., et al. Effect of eradication of Helicobacter pylori on incidence of metachronous gastric carcinoma after endoscopic resection of early gastric cancer: an open-label, randomised controlled trial. Lancet 372 (2008) 392-397
22. Take S., Mizuno M., Ishiki K., et al. The effect of eradicating Helicobacter pylori on the development of gastric cancer in patients with peptic ulcer disease. Am J Gastroenterol 100 (2005) 1037-1042
23. Gonzalez-Perez A., Garcia Rodriguez L.A., and Lopez-Ridaura R. Effects of non-steroidal anti-inflammatory drugs on cancer sites other than the colon and rectum: a meta-analysis. BMC Cancer 3 (2003) 28-39
24. Wang W.H., Huang J.Q., Zheng G.F., et al. Non-steroidal anti-inflammatory drug use and the risk of gastric cancer: a systematic review and meta-analysis. J Natl Cancer Inst 95 (2003) 1784-1791
25. Wu C.W., Hsieh M.C., Lo S.S., et al. Prognostic indicators for survival after curative resection for patients with carcinoma of the stomach. Dig Dis Sci 42 (1997) 1265-1269
26. Lee Y.C., Wu H.M., Chen, et al. A community-based study of Helicobacter pylori therapy using the strategy of test, treat, retest, and re-treat initial treatment failures. Helicobacter 11 (2006) 418-424