-
1
-
-
69149097198
-
-
Available at: Last accessed: 2009 June 8
-
National Multiple Sclerosis Society. About MS. Available at: http://www.nationalmssociety.org/about-multiple-sclerosis/index.aspx [Last accessed: 2009 June 8]
-
About MS
-
-
-
2
-
-
0027418515
-
Interferon beta-1b is effective in relapsing-remitting multiple sclerosis. I. Clinical results of a multicenter, randomized, double-blind, placebo-controlled trial
-
The IFNB Multiple Sclerosis Study Group.
-
The IFNB Multiple Sclerosis Study Group. Interferon beta-1b is effective in relapsing-remitting multiple sclerosis. I. Clinical results of a multicenter, randomized, double-blind, placebo-controlled trial. Neurology 1993;43:655-661
-
(1993)
Neurology
, vol.43
, pp. 655-661
-
-
-
3
-
-
0345601517
-
Randomised double-blind placebo-controlled study of interferon beta-1a in relapsing/remitting multiple sclerosis
-
The PRISMS Study Group. PRISMS (Prevention of Relapses and Disability by Interferon beta-1a Subcutaneously in Multiple Sclerosis) Study Group
-
The PRISMS Study Group. Randomised double-blind placebo-controlled study of interferon beta-1a in relapsing/remitting multiple sclerosis. PRISMS (Prevention of Relapses and Disability by Interferon beta-1a Subcutaneously in Multiple Sclerosis) Study Group. Lancet 1998;352:1498-1504
-
(1998)
Lancet
, vol.352
, pp. 1498-1504
-
-
-
4
-
-
0008678962
-
Intramuscular interferon beta-1a for disease progression in relapsing multiple sclerosis
-
DOI 10.1002/ana.410390304
-
Jacobs LD, Cookfair DL, Rudick RA, et al. Intramuscular interferon beta-1a for disease progression in relapsing multiple sclerosis. The Multiple Sclerosis Collaborative Research Group (MSCRG). Ann Neurol 1996;39:285-294 (Pubitemid 26100751)
-
(1996)
Annals of Neurology
, vol.39
, Issue.3
, pp. 285-294
-
-
Jacobs, L.D.1
Cookfair, D.L.2
Rudick, R.A.3
Herndon, R.M.4
Richert, J.R.5
Salazar, A.M.6
Fischer, J.S.7
Goodkin, D.E.8
Granger, C.V.9
Simon, J.H.10
Alam, J.J.11
Bartoszak, D.M.12
Bourdette, D.N.13
Braiman, J.14
Brownscheidle, C.M.15
Coats, M.E.16
Cohan, S.L.17
Dougherty, D.S.18
Kinkel, R.P.19
Mass, M.K.20
Munschauer III, F.E.21
Priore, R.L.22
Pullicino, P.M.23
Scherokman, B.J.24
Weinstock-Guttman, B.25
Whitham, R.H.26
more..
-
5
-
-
0029082566
-
Copolymer 1 reduces relapse rate and improves disability in relapsing-remitting multiple sclerosis: Results of a phase III multicenter, double-blind placebo-controlled trial
-
The Copolymer 1 Multiple Sclerosis Study Group
-
Johnson KP, Brooks BR, Cohen JA, et al. Copolymer 1 reduces relapse rate and improves disability in relapsing-remitting multiple sclerosis: results of a phase III multicenter, double-blind placebo-controlled trial. The Copolymer 1 Multiple Sclerosis Study Group. Neurology 1995;45:1268-1276
-
(1995)
Neurology
, vol.45
, pp. 1268-1276
-
-
Johnson, K.P.1
Brooks, B.R.2
Cohen, J.A.3
-
6
-
-
33644584352
-
A randomized, placebo-controlled trial of natalizumab for relapsing multiple sclerosis
-
DOI 10.1056/NEJMoa044397
-
Polman CH, O'Connor PW, Havrdova E, et al. A randomized, placebo-controlled trial of natalizumab for relapsing multiple sclerosis. N Engl J Med 2006;354:899-910 (Pubitemid 43313657)
-
(2006)
New England Journal of Medicine
, vol.354
, Issue.9
, pp. 899-910
-
-
Polman, C.H.1
O'Connor, P.W.2
Havrdova, E.3
Hutchinson, M.4
Kappos, L.5
Miller, D.H.6
Phillips, J.T.7
Lublin, F.D.8
Giovannoni, G.9
Wajgt, A.10
Toal, M.11
Lynn, F.12
Panzara, M.A.13
Sandrock, A.W.14
-
7
-
-
0037153729
-
Mitoxantrone in progressive multiple sclerosis: A placebo-controlled, double-blind, randomised, multicentre trial
-
DOI 10.1016/S0140-6736(02)12023-X
-
Hartung HP, Gonsette R, Konig N, et al. Mitoxantrone in progressive multiple sclerosis: a placebo-controlled, double-blind, randomised, multicentre trial. Lancet 2002;360:2018-2025 (Pubitemid 36026580)
-
(2002)
Lancet
, vol.360
, Issue.9350
, pp. 2018-2025
-
-
Hartung, H.-P.1
Gonsette, R.2
Konig, N.3
Kwiecinski, H.4
Guseo, A.5
Morrissey, S.P.6
Krapf, H.7
Zwingers, T.8
Albrecht, H.9
Basedow-Rajwich, B.10
Hofmeister, R.11
Pollmann, W.12
Starck, M.13
Beer, K.14
Hopf, H.C.15
Kohler, J.16
Lensch, E.17
Besinger, U.18
Vom Dahl, M.19
Hendrich, A.20
Loser, M.21
Braun, M.22
Greiling, H.W.23
Greve, H.24
Kohl, D.25
Merkel, M.26
Conrad, B.27
Konstanzer, A.28
Kornhuber, M.29
Dierkes, W.30
Munz, T.31
Zenker, O.32
Flachenecker, P.M.33
Weilbach, F.X.34
Haas, J.35
Hauser, U.36
Kompf, D.37
Moser, A.38
Scholz, J.39
Weigle, L.-J.40
Branas, C.41
Sadzot, B.42
Cras, P.43
Dams, L.44
Vande Gaer, L.45
Demonty, L.46
Lissoir, F.47
Guillaume, D.48
Seeldrayers, P.49
Peeters, B.50
Hosszu, Z.51
Jofeju, E.52
Janiec, K.53
Lubos, L.54
Waigt, A.55
Kaminska, A.M.56
Zakrzewska-Pniewska, B.57
more..
-
8
-
-
10744230723
-
Glatiramer acetate (Copaxone): Comparison of continuous versus delayed therapy in a six-year organized multiple sclerosis trial
-
Johnson KP, Brooks BR, Ford CC, et al. Glatiramer acetate (Copaxone): comparison of continuous versus delayed therapy in a six-year organized multiple sclerosis trial. Mult Scler 2003;9:585-591
-
(2003)
Mult Scler
, vol.9
, pp. 585-591
-
-
Johnson, K.P.1
Brooks, B.R.2
Ford, C.C.3
-
9
-
-
0036189052
-
Use of interferon beta in multiple sclerosis: Rationale for early treatment and evidence for dose- And frequency-dependent effects on clinical response
-
Coyle PK, Hartung HP. Use of interferon beta in multiple sclerosis: rationale for early treatment and evidence for dose- and frequency-dependent effects on clinical response. Mult Scler 2002;8:2-9
-
(2002)
Mult Scler
, vol.8
, pp. 2-9
-
-
Coyle, P.K.1
Hartung, H.P.2
-
10
-
-
34547497820
-
Effect of early versus delayed interferon beta-1b treatment on disability after a first clinical event suggestive of multiple sclerosis: A 3-year follow-up analysis of the BENEFIT study
-
DOI 10.1016/S0140-6736(07)61194-5, PII S0140673607611945
-
Kappos L, Freedman MS, Polman CH, et al. Effect of early versus delayed interferon beta-1b treatment on disability after a first clinical event suggestive of multiple sclerosis: a 3-year follow-up analysis of the BENEFIT study. Lancet 2007;370:389-397 (Pubitemid 47189673)
-
(2007)
Lancet
, vol.370
, Issue.9585
, pp. 389-397
-
-
Kappos, L.1
Freedman, M.S.2
Polman, C.H.3
Edan, G.4
Hartung, H.-P.5
Miller, D.H.6
Montalban, X.7
Barkhof, F.8
Radu, E.-W.9
Bauer, L.10
Dahms, S.11
Lanius, V.12
Pohl, C.13
Sandbrink, R.14
-
11
-
-
0035912520
-
Effect of early interferon treatment on conversion to definite multiple sclerosis: A randomised study
-
DOI 10.1016/S0140-6736(00)04725-5
-
Comi G, Filippi M, Barkhof F, et al. Effect of early interferon treatment on conversion to definite multiple sclerosis: a randomised study. Lancet 2001;357:1576-1582 (Pubitemid 32488815)
-
(2001)
Lancet
, vol.357
, Issue.9268
, pp. 1576-1582
-
-
Comi, G.1
Filippi, M.2
Barkhof, F.3
Durelli, L.4
Edan, G.5
Fernandez, O.6
Hartung, H.-P.7
Seeldrayers, P.8
Sorensen, P.S.9
Rovaris, M.10
Martinelli, V.11
Hommes, O.R.12
-
12
-
-
0034727059
-
Intramuscular interferon beta-1a therapy initiated during a first demyelinating event in multiple sclerosis
-
Jacobs LD, Beck RW, Simon JH, et al. Intramuscular interferon beta-1a therapy initiated during a first demyelinating event in multiple sclerosis. N Engl J Med 2000;343:898-904
-
(2000)
N Engl J Med
, vol.343
, pp. 898-904
-
-
Jacobs, L.D.1
Beck, R.W.2
Simon, J.H.3
-
13
-
-
53649096539
-
Induction vs. escalation of therapy for relapsing multiple sclerosis: The evidence
-
Freedman MS. Induction vs. escalation of therapy for relapsing multiple sclerosis: the evidence. Neurol Sci 2008;29(Suppl 2):S250-2
-
(2008)
Neurol Sci
, vol.29
, Issue.SUPPL. 2
-
-
Freedman, M.S.1
-
14
-
-
34248359578
-
Natural history of multiple sclerosis: Risk factors and prognostic indicators
-
DOI 10.1097/WCO.0b013e32812583ad, PII 0001905220070600000005
-
Vukusic S, Confavreux C. Natural history of multiple sclerosis: risk factors and prognostic indicators. Curr Opin Neurol 2007;20:269-274 (Pubitemid 46743107)
-
(2007)
Current Opinion in Neurology
, vol.20
, Issue.3
, pp. 269-274
-
-
Vukusic, S.1
Confavreux, C.2
-
15
-
-
0037105986
-
Optimizing immunomodulatory therapy for MS patients: An integrated management model
-
DOI 10.1016/S0022-510X(02)00195-8, PII S0022510X02001958
-
Bashir K, Buchwald L, Coyle P, et al. MS patient management: optimizing immunomodulatory therapy for MS patients. Int J MS Care 2002;(Jun Suppl):1-7 (Pubitemid 34876911)
-
(2002)
Journal of the Neurological Sciences
, vol.201
, Issue.1-2
, pp. 89-90
-
-
Jeffery, D.1
Bashir, K.2
Buchwald, L.3
Coyle, P.4
Freedman, M.5
Markowitz, C.6
Rammohan, K.7
Reder, T.8
Sharief, M.9
Wolinsky, J.10
-
16
-
-
19944415573
-
Identifying and treating patients with suboptimal responses
-
Cohen BA, Khan O, Jeffery DR, et al. Identifying and treating patients with suboptimal responses. Neurology 2004;63:S33-40 (Pubitemid 40019277)
-
(2004)
Neurology
, vol.63
, Issue.12 SUPPL. 6
-
-
Cohen, B.A.1
Khan, O.2
Jeffery, D.R.3
Bashir, K.4
Rizvi, S.A.5
Fox, E.J.6
Agius, M.7
Bashir, R.8
Collins, T.E.9
Herndon, R.10
Kinkel, P.11
Mikol, D.D.12
Picone, M.A.13
Rivera, V.14
Tornatore, C.15
Zwibel, H.16
-
18
-
-
0842330009
-
Treatment optimization in multiple sclerosis: Report of an international consensus meeting
-
International Working Group for Treatment Optimization in MS
-
International Working Group for Treatment Optimization in MS. Treatment optimization in multiple sclerosis: report of an international consensus meeting. Eur J Neurol 2004;11:43-47
-
(2004)
Eur J Neurol
, vol.11
, pp. 43-47
-
-
-
19
-
-
59249084508
-
Canadian treatment optimization recommendations (TOR) as a predictor of disease breakthrough in patients with multiple sclerosis treated with interferon {beta}-1a: Analysis of the PRISMS study
-
Freedman MS, Forrestal FG. Canadian treatment optimization recommendations (TOR) as a predictor of disease breakthrough in patients with multiple sclerosis treated with interferon {beta}-1a: analysis of the PRISMS study. Mult Scler 2008;14:1234-1241
-
(2008)
Mult Scler
, vol.14
, pp. 1234-1241
-
-
Freedman, M.S.1
Forrestal, F.G.2
-
20
-
-
42249090564
-
Optimization of treatment with interferon beta in multiple sclerosis. Usefulness of automatic system application criteria
-
Ruiz-Pena JL, Duque P, Izquierdo G. Optimization of treatment with interferon beta in multiple sclerosis. Usefulness of automatic system application criteria. BMC Neurol 2008;8:3
-
(2008)
BMC Neurol
, vol.8
, pp. 3
-
-
Ruiz-Pena, J.L.1
Duque, P.2
Izquierdo, G.3
-
21
-
-
33645238738
-
A recommended treatment algorithm in relapsing multiple sclerosis: Report of an international consensus meeting
-
Karussis D, Biermann LD, Bohlega S, et al. A recommended treatment algorithm in relapsing multiple sclerosis: report of an international consensus meeting. Eur J Neurol 2006;13:61-71
-
(2006)
Eur J Neurol
, vol.13
, pp. 61-71
-
-
Karussis, D.1
Biermann, L.D.2
Bohlega, S.3
-
22
-
-
4344640131
-
Clinical management of multiple sclerosis: The treatment paradigm and issues of patient management
-
Stuart WH. Clinical management of multiple sclerosis: the treatment paradigm and issues of patient management. J Manag Care Pharm 2004;10(3 Suppl S-b):S19-25
-
(2004)
J Manag Care Pharm
, vol.10
, Issue.3 SUPPL. S-B
-
-
Stuart, W.H.1
-
23
-
-
4344593040
-
Stepped-care approach to treating MS: A managed care treatment algorithm
-
Rich SR, Coleman IC, Cook R, et al. Stepped-care approach to treating MS: a managed care treatment algorithm. J Manag Care Pharm 2004;10(3 Suppl S-b):S26-32
-
(2004)
J Manag Care Pharm
, vol.10
, Issue.3 SUPPL. S-B
-
-
Rich, S.R.1
Coleman, I.C.2
Cook, R.3
-
24
-
-
12744261338
-
Escalating immunotherapy of multiple sclerosis - New aspects and practical application
-
Rieckmann P, Toyka KV, Bassetti C, et al. Escalating immunotherapy of multiple sclerosis - new aspects and practical application. J Neurol 2004;251:1329-1339
-
(2004)
J Neurol
, vol.251
, pp. 1329-1339
-
-
Rieckmann, P.1
Toyka, K.V.2
Bassetti, C.3
-
25
-
-
0038115303
-
Longitudinal MRI study: The effects of azathioprine in MS patients refractory to interferon beta-1b
-
Markovic-Plese S, Bielekova B, Kadom N, et al. Longitudinal MRI study: the effects of azathioprine in MS patients refractory to interferon beta-1b. Neurology 2003;60:1849-1851 (Pubitemid 36737092)
-
(2003)
Neurology
, vol.60
, Issue.11
, pp. 1849-1851
-
-
Markovic-Plese, S.1
Bielekova, B.2
Kadom, N.3
Leist, T.P.4
Martin, R.5
Frank, J.A.6
McFarland, H.F.7
-
26
-
-
34547418139
-
Combination therapy with interferon-beta and glatiramer acetate in multiple sclerosis
-
DOI 10.1111/j.1600-0404.2007.00801.x
-
Ytterberg C, Johansson S, Andersson M, et al. Combination therapy with interferon-beta and glatiramer acetate in multiple sclerosis. Acta Neurol Scand 2007;116:96-99 (Pubitemid 47174182)
-
(2007)
Acta Neurologica Scandinavica
, vol.116
, Issue.2
, pp. 96-99
-
-
Ytterberg, C.1
Johansson, S.2
Andersson, M.3
Olsson, D.4
Link, H.5
Holmqvist, L.W.6
Von Koch, L.7
-
27
-
-
33749627690
-
High-dose cyclophosphamide for moderate to severe refractory multiple sclerosis
-
DOI 10.1001/archneur.63.10.noc60076
-
Gladstone DE, Zamkoff KW, Krupp L, et al. High-dose cyclophosphamide for moderate to severe refractory multiple sclerosis. Arch Neurol 2006;63:1388-1393 (Pubitemid 44547549)
-
(2006)
Archives of Neurology
, vol.63
, Issue.10
, pp. 1388-1393
-
-
Gladstone, D.E.1
Zamkoff, K.W.2
Krupp, L.3
Peyster, R.4
Sibony, P.5
Christodoulou, C.6
Locher, E.7
Coyle, P.K.8
-
28
-
-
33744758685
-
Clinical course after change of immunomodulating therapy in relapsing - Remitting multiple sclerosis
-
DOI 10.1111/j.1468-1331.2006.01273.x
-
Caon C, Din M, Ching W, et al. Clinical course after change of immunomodulating therapy in relapsing-remitting multiple sclerosis. Eur J Neurol 2006;13:471-474 (Pubitemid 43823361)
-
(2006)
European Journal of Neurology
, vol.13
, Issue.5
, pp. 471-474
-
-
Caon, C.1
Din, M.2
Ching, W.3
Tselis, A.4
Lisak, R.5
Khan, O.6
-
29
-
-
41049110806
-
Therapeutic outcome 3 years after switching of immunomodulatory therapies in patients with relapsing- Remitting multiple sclerosis in Argentina
-
Carrá A, Onaha P, Luetic G, et al. Therapeutic outcome 3 years after switching of immunomodulatory therapies in patients with relapsing- remitting multiple sclerosis in Argentina. Eur J Neurol 2008;15:386-393
-
(2008)
Eur J Neurol
, vol.15
, pp. 386-393
-
-
Carrá, A.1
Onaha, P.2
Luetic, G.3
-
30
-
-
15544375688
-
Optimization of the safety and efficacy of interferon beta 1b and azathioprine combination therapy in multiple sclerosis
-
DOI 10.1191/1352458505ms1141oa
-
Pulicken M, Bash CN, Costello K, et al. Optimization of the safety and efficacy of interferon beta-1b and azathioprine combination therapy in multiple sclerosis. Mult Scler 2005;11:169-174 (Pubitemid 40403255)
-
(2005)
Multiple Sclerosis
, vol.11
, Issue.2
, pp. 169-174
-
-
Pulicken, M.1
Bash, C.N.2
Costello, K.3
Said, A.4
Cuffari, C.5
Wilterdink, J.L.6
Rogg, J.M.7
Mills, P.8
Calabresi, P.A.9
-
31
-
-
70350099155
-
Mitoxantrone in MS patients, non-responders to interferon
-
Téllez N, Río J, Tintoré M, et al. Mitoxantrone in MS patients, non-responders to interferon. 21st Congress of the European Committee for the Treatment and Research in Multiple Sclerosis 2005 September 28-October 1, Madrid, Spain
-
21st Congress of the European Committee for the Treatment and Research in Multiple Sclerosis 2005 September 28-October 1, Madrid, Spain
-
-
Téllez, N.1
Río, J.2
Tintoré, M.3
-
32
-
-
0348047252
-
1a in relapsing-remitting multiple sclerosis patients: Increasing efficacy of combined treatment
-
DOI 10.1159/000074912
-
Lus G, Romano F, Scuotto A, et al. Azathioprine and interferon beta(1a) in relapsing-remitting multiple sclerosis patients: increasing efficacy of combined treatment. Eur Neurol 2004;51:15-20 (Pubitemid 38041613)
-
(2004)
European Neurology
, vol.51
, Issue.1
, pp. 15-20
-
-
Lus, G.1
Romano, F.2
Scuotto, A.3
Accardo, C.4
Cotrufo, R.5
-
33
-
-
26644463420
-
The combination of cyclophosphamide plus interferon beta as rescue therapy could be used to treat relapsing-remitting multiple sclerosis patients: Twenty-four months follow-up
-
DOI 10.1007/s00415-005-0857-1
-
Reggio E, Nicoletti A, Fiorilla T, et al. The combination of cyclophosphamide plus interferon beta as rescue therapy could be used to treat relapsing-remitting multiple sclerosis patients - twenty-four months follow-up. J Neurol 2005;252:1255-1261 (Pubitemid 41443628)
-
(2005)
Journal of Neurology
, vol.252
, Issue.10
, pp. 1255-1261
-
-
Reggio, E.1
Nicoletti, A.2
Fiorilla, T.3
Politi, G.4
Reggio, A.5
Patti, F.6
-
34
-
-
17044391471
-
Mitoxantrone as rescue therapy in worsening relapsing-remitting MS patients receiving IFN-beta
-
DOI 10.1016/j.jneuroim.2005.02.003
-
Correale J, Rush C, Amengual A, et al. Mitoxantrone as rescue therapy in worsening relapsing-remitting MS patients receiving IFN-beta. J Neuroimmunol 2005;162:173-183 (Pubitemid 40503112)
-
(2005)
Journal of Neuroimmunology
, vol.162
, Issue.1-2
, pp. 173-183
-
-
Correale, J.1
Rush, C.2
Amengual, A.3
Goicochea, M.T.4
-
35
-
-
2942537826
-
Humanized anti-CD25 (daclizumab) inhibits disease activity in multiple sclerosis patients failing to respond to interferon beta
-
DOI 10.1073/pnas.0402653101
-
Bielekova B, Richert N, Howard T, et al. Humanized anti-CD25 (daclizumab) inhibits disease activity in multiple sclerosis patients failing to respond to interferon beta. Proc Natl Acad Sci U S A 2004;101:8705-8708 (Pubitemid 38745835)
-
(2004)
Proceedings of the National Academy of Sciences of the United States of America
, vol.101
, Issue.23
, pp. 8705-8708
-
-
Bielekova, B.1
Richert, N.2
Howard, T.3
Blevins, G.4
Markovic-Plese, S.5
McCartin, J.6
Wurfel, J.7
Ohayon, J.8
Waldmann, T.A.9
McFarland, H.F.10
Martin, R.11
-
36
-
-
0037154138
-
An open-label trial of combination therapy with interferon beta-1a and oral methotrexate in MS
-
Calabresi PA, Wilterdink JL, Rogg JM, et al. An open-label trial of combination therapy with interferon beta-1a and oral methotrexate in MS. Neurology 2002;58:314-317
-
(2002)
Neurology
, vol.58
, pp. 314-317
-
-
Calabresi, P.A.1
Wilterdink, J.L.2
Rogg, J.M.3
-
37
-
-
39049136067
-
Combination therapy with interferon beta-1a and doxycycline in multiple sclerosis: An open-label trial
-
DOI 10.1001/archneurol.2007.41
-
Minagar A, Alexander JS, Schwendimann RN et al. Combination therapy with interferon beta-1a and doxycycline in multiple sclerosis: an open-label trial. Arch Neurol 2008;65:199-204 (Pubitemid 351240780)
-
(2008)
Archives of Neurology
, vol.65
, Issue.2
, pp. 199-204
-
-
Minagar, A.1
Alexander, J.S.2
Schwendimann, R.N.3
Kelley, R.E.4
Gonzalez-Toledo, E.5
Jimenez, J.J.6
Mauro, L.7
Jy, W.8
Smith, S.J.9
-
38
-
-
34548142973
-
Daclizumab phase II trial in relapsing and remitting multiple sclerosis: MRI and clinical results
-
DOI 10.1212/01.wnl.0000267662.41734.1f, PII 0000611420070821000012
-
Rose JW, Burns JB, Bjorklund J, et al. Daclizumab phase II trial in relapsing and remitting multiple sclerosis: MRI and clinical results. Neurology 2007;69:785-789 (Pubitemid 47300936)
-
(2007)
Neurology
, vol.69
, Issue.8
, pp. 785-789
-
-
Rose, J.W.1
Burns, J.B.2
Bjorklund, J.3
Klein, J.4
Watt, H.E.5
Carlson, N.G.6
-
39
-
-
25844530825
-
A randomized blinded trial of combination therapy with cyclophosphamide in patients with active multiple sclerosis on interferon beta
-
DOI 10.1191/1352458505ms1210oa
-
Smith DR, Weinstock-Guttman B, Cohen JA, et al. A randomized blinded trial of combination therapy with cyclophosphamide in patients-with active multiple sclerosis on interferon beta. Mult Scler 2005;11:573-582 (Pubitemid 41387703)
-
(2005)
Multiple Sclerosis
, vol.11
, Issue.5
, pp. 573-582
-
-
Smith, D.R.1
Weinstock-Guttman, B.2
Cohen, J.A.3
Wei, X.4
Gutmann, C.5
Bakshi, R.6
Olek, M.7
Stone, L.8
Greenberg, S.9
Stuart, D.10
Orav, J.11
Stuart, W.12
Weiner, H.13
-
40
-
-
43549110503
-
Avonex Combination Trial in relapsing-remitting MS: Rationale, design and baseline data
-
DOI 10.1177/1352458507083189
-
Cohen JA, Calabresi PA, Chakraborty S, et al. Avonex Combination Trial in relapsing-remitting MS: rationale, design and baseline data. Mult Scler 2008;14:370-382 (Pubitemid 351676432)
-
(2008)
Multiple Sclerosis
, vol.14
, Issue.3
, pp. 370-382
-
-
Cohen, J.A.1
Calabresi, P.A.2
Chakraborty, S.3
Edwards, K.R.4
Eickenhorst, T.5
Felton III, W.L.6
Fisher, E.7
Fox, R.J.8
Goodman, A.D.9
Hara-Cleaver, C.10
Hutton, G.J.11
Imrey, P.B.12
Ivancic, D.M.13
Mandell, B.F.14
Perryman, J.E.15
Scott, T.F.16
Skaramagas, T.T.17
Zhang, H.18
-
41
-
-
33644608613
-
Natalizumab plus interferon beta-1a for relapsing multiple sclerosis
-
DOI 10.1056/NEJMoa044396
-
Rudick RA, Stuart WH, Calabresi PA, et al. Natalizumab plus interferon beta- 1a for relapsing multiple sclerosis. N Engl J Med 2006;354:911-923 (Pubitemid 43313658)
-
(2006)
New England Journal of Medicine
, vol.354
, Issue.9
, pp. 911-923
-
-
Rudick, R.A.1
Stuart, W.H.2
Calabresi, P.A.3
Confavreux, C.4
Galetta, S.L.5
Radue, E.-W.6
Lublin, F.D.7
Weinstock-Guttman, B.8
Wynn, D.R.9
Lynn, F.10
Panzara, M.A.11
Sandrock, A.W.12
-
42
-
-
0037180479
-
Randomized, comparative study of interferon beta-1a treatment regimens in MS: The evidence trial
-
Panitch H, Goodin DS, Francis G, et al. Randomized, comparative study of interferon beta-1a treatment regimens in MS: the EVIDENCE Trial. Neurology 2002;59:1496-1506 (Pubitemid 35387053)
-
(2002)
Neurology
, vol.59
, Issue.10
, pp. 1496-1506
-
-
Panitch, H.1
Goodin, D.S.2
Francis, G.3
Chang, P.4
Coyle, P.K.5
O'Connor, P.6
Monaghan, E.7
Li, D.8
Weinshenker, B.9
-
43
-
-
0037181634
-
Every-other-day interferon beta-1b versus once-weekly interferon beta-1a for multiple sclerosis: Results of a 2-year prospective randomised multicentre study (INCOMIN)
-
DOI 10.1016/S0140-6736(02)08430-1
-
Durelli L, Verdun E, Barbero P, et al. Every-other-day interferon beta-1b versus once-weekly interferon beta-1a for multiple sclerosis: results of a 2-year prospective randomised multicentre study (INCOMIN). Lancet 2002;359:1453-1460 (Pubitemid 34457761)
-
(2002)
Lancet
, vol.359
, Issue.9316
, pp. 1453-1460
-
-
Durelli, L.1
Verdun, E.2
Barbero, P.3
Bergui, M.4
Versino, E.5
Ghezzi, A.6
Montanari, E.7
Zaffaroni, M.8
-
44
-
-
55149115659
-
The OPTimization of Interferon for MS Study: 375 mug interferon beta-1b in suboptimal responders
-
Durelli L, Barbero P, Bergui M, et al. The OPTimization of Interferon for MS Study: 375 mug interferon beta-1b in suboptimal responders. J Neurol 2008;255:1315-1323
-
(2008)
J Neurol
, vol.255
, pp. 1315-1323
-
-
Durelli, L.1
Barbero, P.2
Bergui, M.3
-
45
-
-
0035954361
-
PRISMS-4: Long-term efficacy of interferon-beta- 1a in relapsing MS
-
The PRISMS Study Group
-
The PRISMS Study Group. PRISMS-4: long-term efficacy of interferon-beta- 1a in relapsing MS. Neurology 2001;56:1628-1636
-
(2001)
Neurology
, vol.56
, pp. 1628-1636
-
-
-
46
-
-
58149085571
-
Switching first-line disease-modifying therapy after failure: Impact on the course of relapsing-remitting multiple sclerosis
-
Gajofatto A, Bacchetti P, Grimes B, et al. Switching first-line disease-modifying therapy after failure: impact on the course of relapsing-remitting multiple sclerosis. Mult Scler 2009;15:50-58
-
(2009)
Mult Scler
, vol.15
, pp. 50-58
-
-
Gajofatto, A.1
Bacchetti, P.2
Grimes, B.3
-
48
-
-
70350090543
-
-
Available at: Last accessed: 2009 March 31
-
TYSABRI® (natalizumab) Information Center, 2009. Available at: http://www.biogenidec.com/site/tysabri-information-center.html [Last accessed: 2009 March 31]
-
(2009)
-
-
-
49
-
-
62149143732
-
Results of the Avonex Combination Trial (ACT) in relapsing-remitting MS
-
Cohen JA, Imrey PB, Calabresi PA, et al. Results of the Avonex Combination Trial (ACT) in relapsing-remitting MS. Neurology 2009;72:535-541
-
(2009)
Neurology
, vol.72
, pp. 535-541
-
-
Cohen, J.A.1
Imrey, P.B.2
Calabresi, P.A.3
-
50
-
-
0036789860
-
Assessment of different treatment failure criteria in a cohort of relapsing-remitting multiple sclerosis patients treated with interferon beta: Implications for clinical trials
-
Rio J, Nos C, Tintore M, et al. Assessment of different treatment failure criteria in a cohort of relapsing-remitting multiple sclerosis patients treated with interferon beta: implications for clinical trials. Ann Neurol 2002;52:400-406
-
(2002)
Ann Neurol
, vol.52
, pp. 400-406
-
-
Rio, J.1
Nos, C.2
Tintore, M.3
-
51
-
-
30644467628
-
Treatment optimisation in multiple sclerosis
-
Zaffaroni M. Treatment optimisation in multiple sclerosis. Neurol Sci 2005;26(Suppl 4):S187-92
-
(2005)
Neurol Sci
, vol.26
, Issue.SUPPL. 4
-
-
Zaffaroni, M.1
-
52
-
-
34248180598
-
Predicting beta-interferon failure in relapsing-remitting multiple sclerosis
-
DOI 10.1177/1352458506071309
-
O'Rourke K, Walsh C, Antonelli G, et al. Predicting beta-interferon failure in relapsing-remitting multiple sclerosis. Mult Scler 2007;13:336-342 (Pubitemid 46705994)
-
(2007)
Multiple Sclerosis
, vol.13
, Issue.3
, pp. 336-342
-
-
O'Rourke, K.1
Walsh, C.2
Antonelli, G.3
Hutchinson, M.4
-
53
-
-
32044463386
-
Defining the response to interferon-beta in relapsing-remitting multiple sclerosis patients
-
Rio J, Nos C, Tintore M, et al. Defining the response to interferon-beta in relapsing-remitting multiple sclerosis patients. Ann Neurol 2006;59:344-352
-
(2006)
Ann Neurol
, vol.59
, pp. 344-352
-
-
Rio, J.1
Nos, C.2
Tintore, M.3
-
54
-
-
0035174606
-
Sjögren's syndrome with central nervous system involvement presenting as multiple sclerosis with failure response to beta-interferon
-
DOI 10.1159/000052095
-
Tsai KY, Tsai CP, Liao N. Sjögren's syndrome with central nervous system involvement presenting as multiple sclerosis with failure response to beta-interferon. Eur Neurol 2001;45:59-60 (Pubitemid 32041393)
-
(2001)
European Neurology
, vol.45
, Issue.1
, pp. 59-60
-
-
Tsai, K.-Y.1
Tsai, C.-P.2
Liao, N.3
-
55
-
-
34250749606
-
Natural history of multiple sclerosis with childhood onset
-
DOI 10.1056/NEJMoa067597
-
Renoux C, Vukusic S, Mikaeloff Y, et al. Natural history of multiple sclerosis with childhood onset. N Engl J Med 2007;356:2603-2613 (Pubitemid 46961005)
-
(2007)
New England Journal of Medicine
, vol.356
, Issue.25
, pp. 2603-2613
-
-
Renoux, C.1
Vukusic, S.2
Mikaeloff, Y.3
Edan, G.4
Clanet, M.5
Dubois, B.6
Debouverie, M.7
Brochet, B.8
Lebrun-Frenay, C.9
Pelletier, J.10
Moreau, T.11
Lubetzki, C.12
Vermersch, P.13
Roullet, E.14
Magy, L.15
Tardieu, M.16
Suissa, S.17
Confavreux, C.18
-
56
-
-
33244466021
-
Natural history of multiple sclerosis: A unifying concept
-
DOI 10.1093/brain/awl007
-
Confavreux C, Vukusic S. Natural history of multiple sclerosis: a unifying concept. Brain 2006;129:606-616 (Pubitemid 43278223)
-
(2006)
Brain
, vol.129
, Issue.3
, pp. 606-616
-
-
Confavreux, C.1
Vukusic, S.2
-
57
-
-
33644964929
-
Predictors of long-term clinical response to interferon beta therapy in relapsing multiple sclerosis
-
Tomassini V, Paolillo A, Russo P, et al. Predictors of long-term clinical response to interferon beta therapy in relapsing multiple sclerosis. J Neurol 2006;253:287-293
-
(2006)
J Neurol
, vol.253
, pp. 287-293
-
-
Tomassini, V.1
Paolillo, A.2
Russo, P.3
-
58
-
-
33646685266
-
Does multiple sclerosis-associated disability differ between races?
-
Marrie RA, Cutter G, Tyry T, et al. Does multiple sclerosis-associated disability differ between races? Neurology 2006;66:1235-1240
-
(2006)
Neurology
, vol.66
, pp. 1235-1240
-
-
Marrie, R.A.1
Cutter, G.2
Tyry, T.3
-
59
-
-
33846335209
-
Phenotype and prognosis in African-Americans with multiple sclerosis: A retrospective chart review
-
DOI 10.1177/1352458506070923
-
Naismith RT, Trinkaus K, Cross AH. Phenotype and prognosis in African- Americans with multiple sclerosis: a retrospective chart review. Mult Scler 2006;12:775-781 (Pubitemid 46111770)
-
(2006)
Multiple Sclerosis
, vol.12
, Issue.6
, pp. 775-781
-
-
Naismith, R.T.1
Trinkaus, K.2
Cross, A.H.3
-
60
-
-
0038660098
-
Multiple sclerosis characteristics in African American patients in the New York State Multiple Sclerosis Consortium
-
DOI 10.1191/1352458503ms909oa
-
Weinstock-Guttman B, Jacobs LD, Brownscheidle CM, et al. Multiple sclerosis characteristics in African American patients in the New York State Multiple Sclerosis Consortium. Mult Scler 2003;9:293-298 (Pubitemid 36681897)
-
(2003)
Multiple Sclerosis
, vol.9
, Issue.3
, pp. 293-298
-
-
Weinstock-Guttman, B.1
Jacobs, L.D.2
Brownscheidle, C.M.3
Baier, M.4
Rea, D.F.5
Apatoff, B.R.6
Blitz, K.M.7
Coyle, P.K.8
Frontera, A.T.9
Goodman, A.D.10
Gottesman, M.H.11
Herbert, J.12
Holub, R.13
Lava, N.S.14
Lenihan, M.15
Lusins, J.16
Mihai, C.17
Miller, A.E.18
Perel, A.B.19
Snyder, D.H.20
Bakshi, R.21
Granger, C.V.22
Greenberg, S.J.23
Jubelt, B.24
Krupp, L.25
Munschauer, F.E.26
Rubin, D.27
Schwid, S.28
Smiroldo, J.29
Cillis, S.30
Walter, P.31
Morgante, L.32
Galey, T.33
Gallagher, E.M.34
Green, L.A.35
Hovey, K.M.36
Justinger, T.A.37
Miller, C.E.38
Nazareth, M.R.39
Patrick, K.40
Planter, M.41
Smith, D.42
Umhauer, M.A.43
Mammano, R.L.44
Galante, K.45
Friedman-Urevich, S.46
Orapelo, C.47
Capolino, L.48
Wozniak, L.49
Petrie, M.50
Pollock, M.L.51
Scheid, E.52
Katkin, I.53
Ingoglia, W.54
Carpenter, J.55
Waterman, L.56
Brownscheidle, C.M.57
more..
-
61
-
-
0041698406
-
Severity and progression rate in African Americans compared with whites
-
DOI 10.1097/00002060-200308000-00003
-
Kaufman MD, Johnson SK, Moyer D, et al. Multiple sclerosis: severity and progression rate in African Americans compared with whites. Am J Phys Med Rehabil 2003;82:582-590 (Pubitemid 36890406)
-
(2003)
American Journal of Physical Medicine and Rehabilitation
, vol.82
, Issue.8
, pp. 582-590
-
-
Kaufman, M.D.1
Johnson, S.K.2
Moyer, D.3
Bivens, J.4
Norton, H.J.5
-
62
-
-
27744582897
-
Response to interferon beta-1a treatment in African American multiple sclerosis patients
-
DOI 10.1001/archneur.62.11.1681
-
Cree BA, AL-Sabbagh A, Bennett R, et al. Response to interferon beta-1a treatment in African American multiple sclerosis patients. Arch Neurol 2005;62:1681-1683 (Pubitemid 41626662)
-
(2005)
Archives of Neurology
, vol.62
, Issue.11
, pp. 1681-1683
-
-
Cree, B.A.C.1
Al-Sabbagh, A.2
Bennett, R.3
Goodin, D.4
-
63
-
-
10444231359
-
Clinical characteristics of African Americans vs Caucasian Americans with multiple sclerosis
-
Cree BA, Khan O, Bourdette D, et al. Clinical characteristics of African Americans vs Caucasian Americans with multiple sclerosis. Neurology 2004;63:2039-2045 (Pubitemid 39636249)
-
(2004)
Neurology
, vol.63
, Issue.11
, pp. 2039-2045
-
-
Cree, B.A.C.1
Khan, O.2
Bourdette, D.3
Goodin, D.S.4
Cohen, J.A.5
Marrie, R.A.6
Glidden, D.7
Weinstock-Guttman, B.8
Reich, D.9
Patterson, N.10
Haines, J.L.11
Pericak-Vance, M.12
Dela, C.13
Oksenberg, J.R.14
Hauser, S.L.15
-
64
-
-
34250637535
-
Neutralizing antibodies in multiple sclerosis: A complex impact on interferon responses, magnetic resonance imaging findings and clinical outcomes
-
DOI 10.1177/1352458507076992
-
Reder A. Neutralizing antibodies in multiple sclerosis: a complex impact on interferon responses, magnetic resonance imaging findings and clinical outcomes. Mult Scler 2007;13(Suppl 1):S53-62 (Pubitemid 46939520)
-
(2007)
Multiple Sclerosis
, vol.13
, Issue.SUPPL. 1
-
-
Reder, A.T.1
-
65
-
-
34147161297
-
Neutralizing antibodies to interferon beta: Assessment of their clinical and radiographic impact: An evidence report: Report of the Therapeutics and Technology Assessment Subcommittee of the American Academy of Neurology
-
DOI 10.1212/01.wnl.0000258545.73854.cf, PII 0000611420070327000006
-
Goodin DS, Frohman EM, Hurwitz B, et al. Neutralizing antibodies to interferon beta: assessment of their clinical and radiographic impact: an evidence report: report of the Therapeutics and Technology Assessment Subcommittee of the American Academy of Neurology. Neurology 2007;68:977-984 (Pubitemid 46569129)
-
(2007)
Neurology
, vol.68
, Issue.13
, pp. 977-984
-
-
Goodin, D.S.1
Frohman, E.M.2
Hurwitz, B.3
O'Connor, P.W.4
Oger, J.J.5
Reder, A.T.6
Stevens, J.C.7
-
66
-
-
27744509228
-
Guidelines on use of anti-IFN-beta antibody measurements in multiple sclerosis: Report of an EFNS Task Force on IFN-beta antibodies in multiple sclerosis
-
DOI 10.1111/j.1468-1331.2005.01386.x
-
Sorensen PS, Deisenhammer F, Duda P, et al. Guidelines on use of anti- IFN-beta antibody measurements in multiple sclerosis: report of an EFNS Task Force on IFN-beta antibodies in multiple sclerosis. Eur J Neurol 2005;12:817-827 (Pubitemid 41597593)
-
(2005)
European Journal of Neurology
, vol.12
, Issue.11
, pp. 817-827
-
-
Sorensen, P.S.1
Deisenhammer, F.2
Duda, P.3
Hohlfeld, R.4
Myhr, K.-M.5
Palace, J.6
Polman, C.7
Pozzilli, C.8
Ross, C.9
-
67
-
-
0031674877
-
Neutralizing antibodies to interferon beta-1a and interferon beta-1b in MS patients are cross-reactive
-
Khan OA, Dhib-Jalbut SS. Neutralizing antibodies to interferon beta-1a and interferon beta-1b in MS patients are cross-reactive. Neurology 1998;51:1698-1702 (Pubitemid 28565255)
-
(1998)
Neurology
, vol.51
, Issue.6
, pp. 1698-1702
-
-
Khan, O.A.1
Dhib-Jalbut, S.S.2
-
68
-
-
62349108495
-
MRI as an outcome in multiple sclerosis clinical trials
-
Daumer M, Neuhaus A, Morrissey S, et al. MRI as an outcome in multiple sclerosis clinical trials. Neurology 2009;72:705-711
-
(2009)
Neurology
, vol.72
, pp. 705-711
-
-
Daumer, M.1
Neuhaus, A.2
Morrissey, S.3
-
69
-
-
39749200152
-
Disability and T2 MRI lesions: A 20-year follow-up of patients with relapse onset of multiple sclerosis
-
Fisniku LK, Brex PA, Altmann DR, et al. Disability and T2 MRI lesions: a 20-year follow-up of patients with relapse onset of multiple sclerosis. Brain 2008;131:808-817
-
(2008)
Brain
, vol.131
, pp. 808-817
-
-
Fisniku, L.K.1
Brex, P.A.2
Altmann, D.R.3
-
70
-
-
4844223606
-
Defining interferon beta response status in multiple sclerosis patients
-
DOI 10.1002/ana.20224
-
Rudick RA, Lee JC, Simon J, et al. Defining interferon beta response status in multiple sclerosis patients. Ann Neurol 2004;56:548-555 (Pubitemid 39319345)
-
(2004)
Annals of Neurology
, vol.56
, Issue.4
, pp. 548-555
-
-
Rudick, R.A.1
Lee, J.-C.2
Simon, J.3
Ransohoff, R.M.4
Fisher, E.5
-
71
-
-
33646197077
-
Diagnosis and management of multiple sclerosis: Case studies
-
Woo DA, Olek MJ, Frohman EM. Diagnosis and management of multiple sclerosis: case studies. Neurol Clin 2006;24:199-214
-
(2006)
Neurol Clin
, vol.24
, pp. 199-214
-
-
Woo, D.A.1
Olek, M.J.2
Frohman, E.M.3
-
73
-
-
34250667954
-
Clinical follow-up of 304 patients with multiple sclerosis three years after mitoxantrone treatment
-
DOI 10.1177/1352458506072543
-
Debouverie M, Taillandier L, Pittion-Vouyovitch S, et al. Clinical follow-up of 304 patients with multiple sclerosis three years after mitoxantrone treatment. Mult Scler 2007;13:626-631 (Pubitemid 46939529)
-
(2007)
Multiple Sclerosis
, vol.13
, Issue.5
, pp. 626-631
-
-
Debouverie, M.1
Taillandier, L.2
Pittion-Vouyovitch, S.3
Louis, S.4
Vespignani, H.5
-
74
-
-
33749432012
-
Sequential maintenance treatment with glatiramer acetate after mitoxantrone is safe and can limit exposure to immunosuppression in very active, relapsing remitting multiple sclerosis
-
DOI 10.1007/s00415-006-0178-z
-
Ramtahal J, Jacob A, Das K, et al. Sequential maintenance treatment with glatiramer acetate after mitoxantrone is safe and can limit exposure to immunosuppression in very active, relapsing remitting multiple sclerosis. J Neurol 2006;253:1160-1164 (Pubitemid 44511472)
-
(2006)
Journal of Neurology
, vol.253
, Issue.9
, pp. 1160-1164
-
-
Ramtahal, J.1
Jacob, A.2
Das, K.3
Boggild, M.4
-
75
-
-
70350117905
-
-
EMD Serono, Inc., and Pfizer Inc, Rockland, MA, and New York, NY
-
Rebif® (interferon beta-1a). Full Prescribing Information, EMD Serono, Inc., and Pfizer Inc, Rockland, MA, and New York, NY, 2008
-
(2008)
Rebif® (Interferon Beta-1a). Full Prescribing Information
-
-
-
78
-
-
4344628691
-
The use of magnetic resonance imaging in multiple sclerosis: Lessons learned from clinical trials
-
DOI 10.1191/1352458504ms1067rr
-
Martinelli Boneschi F, Rovaris M, Comi G, et al. The use of magnetic resonance imaging in multiple sclerosis: lessons learned from clinical trials. Mult Scler 2004;10:341-347 (Pubitemid 39117327)
-
(2004)
Multiple Sclerosis
, vol.10
, Issue.4
, pp. 341-347
-
-
Boneschi, F.M.1
Rovaris, M.2
Comi, G.3
Filippi, M.4
-
80
-
-
33749488304
-
Magnetization transfer MRI metrics predict the accumulation of disability 8 years later in patients with multiple sclerosis
-
DOI 10.1093/brain/awl208
-
Agosta F, Rovaris M, Pagani E, et al. Magnetization transfer MRI metrics predict the accumulation of disability 8 years later in patients with multiple sclerosis. Brain 2006;129:2620-2627 (Pubitemid 44522095)
-
(2006)
Brain
, vol.129
, Issue.10
, pp. 2620-2627
-
-
Agosta, F.1
Rovaris, M.2
Pagani, E.3
Sormani, M.P.4
Comi, G.5
Filippi, M.6
-
81
-
-
20144385804
-
A pilot trial of combination therapy with mitoxantrone and interferon beta-Ib using monthly gadolinium-enhanced magnetic resonance imaging
-
DOI 10.1191/1352458505ms1154oa
-
Jeffery DR, Chepuri N, Durden D, et al. A pilot trial of combination therapy with mitoxantrone and interferon beta-1b using monthly gadolinium-enhanced magnetic resonance imaging. Mult Scler 2005;11:296-301 (Pubitemid 40775185)
-
(2005)
Multiple Sclerosis
, vol.11
, Issue.3
, pp. 296-301
-
-
Jeffery, D.R.1
Chepuri, N.2
Durden, D.3
Burdette, J.4
|