Molecular mechanism of endotoxin tolerance

Hepatology

Volumn 50, Issue 4, 2009, Pages 1322-

  Fujita, Tetsuji ^a  

^a JIKEI UNIVERSITY SCHOOL OF MEDICINE   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

ENDOTOXIN; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; LIPOPOLYSACCHARIDE; MYELOID DIFFERENTIATION FACTOR 88; PROTEIN MD 2; REGULATOR PROTEIN; SUPPRESSOR OF CYTOKINE SIGNALING 1; TOLL LIKE RECEPTOR 4; TOLL LIKE RECEPTOR ADAPTOR MOLECULE 1; INTERLEUKIN 1 RECEPTOR; MEMBRANE PROTEIN; MYD88 PROTEIN, MOUSE; MYELOID DIFFERENTIATION PROTEIN 2, MOUSE; MYELOID DIFFERENTIATION PROTEIN-2, MOUSE; SIGNAL TRANSDUCING ADAPTOR PROTEIN; SOCS1 PROTEIN, MOUSE; SUPPRESSOR OF CYTOKINE SIGNALING; TIRAP PROTEIN, MOUSE; TLR4 PROTEIN, MOUSE;

CELL ISOLATION; CYTOKINE PRODUCTION; DESENSITIZATION; DNA BINDING; DOWN REGULATION; FLUORESCENCE MICROSCOPY; IMMUNOCOMPETENT CELL; KUPFFER CELL; LETTER; LIVER CELL; LIVER DISEASE; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; SIGNAL TRANSDUCTION; UPREGULATION; ANIMAL; DISEASE MODEL; DRUG EFFECT; LIVER; METABOLISM; NOTE; PATHOLOGY; PHYSIOLOGY;

ADAPTOR PROTEINS, SIGNAL TRANSDUCING; ANIMALS; DISEASE MODELS, ANIMAL; ENDOTOXINS; HEPATOCYTES; LIPOPOLYSACCHARIDES; LIVER; LIVER DISEASES; MEMBRANE GLYCOPROTEINS; MICE; MYELOID DIFFERENTIATION FACTOR 88; NF-KAPPA B; RECEPTORS, INTERLEUKIN-1; SIGNAL TRANSDUCTION; SUPPRESSOR OF CYTOKINE SIGNALING PROTEINS; TOLL-LIKE RECEPTOR 4;

EID: 70350075407     PISSN: 02709139     EISSN: None     Source Type: Journal    
DOI: 10.1002/hep.23105     Document Type: Letter

References (3)

1. Scott MJ, Liu S, Shapiro RA, Vodovotz Y, Billiar TR. Endotoxin uptake in mouse liver is blocked by endotoxin pretreatment through a suppressor of cytokine signaling 1-dependent mechanism. HEPATOLOGY 2009;49:1695-1708.
2. Plere CM, Woodward EA, Bisley J, Keith-Magee A, Nicholson SE, Hart PH. SOCS1 regulates the IFN but not NFkB pathway in TLR-stimulated human monocytes and macrophages. J Immunol 2008;181:8018-8026.
3. Jerke S, Srinivasan A, McSorley SJ. Expression of toll/IL-1R domain-containing adaptor protein (TIRAP) is detrimental to primary clearance of Salmonella and is not required for the generation of protective immunity. Immunol Lett 2008;15:64-71.