Interaction between four herb compounds and a western drug by CYP3A4 enzyme metabolism in vitro

Zhongguo Zhongyao Zazhi

Volumn 34, Issue 13, 2009, Pages 1705-1711

  Shen, Guolin ^a   Liang, Aihua ^a   Zhao, Yong ^a   Cao, Chunyu ^a   Liu, Ting ^a   Li, Chunying ^a   Nilsen, Odd Georg ^b  

^a INSTITUTE OF CHINESE MATERIA MEDICA   (China)

^b NORWEGIAN UNIVERSITY OF SCIENCE AND TECHNOLOGY   (Norway)

Author keywords

CYP3A4; Drug interaction; Liver microsomes; Metabolism; Testotesrone

Indexed keywords

6BETA HYDROXYTESTOSTERONE; CHINESE DRUG; CYTOCHROME P450 3A4; NEFERINE; PANAX NOTOGINSENG EXTRACT; SAPONIN DERIVATIVE; TESTOSTERONE; TESTOSTERONE DERIVATIVE; TETRAHYDROPALMATINE; UNCLASSIFIED DRUG;

ANIMAL TISSUE; ARTICLE; CHINESE HERB; DILUTION; ENZYME METABOLISM; HERB DRUG INTERACTION; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; IC 50; IN VITRO STUDY; LIVER METABOLISM; LIVER MICROSOME; METABOLITE; NONHUMAN; PH; RAT; TESTOSTERONE METABOLISM;

ANIMALS; CYTOCHROME P-450 ENZYME SYSTEM; DRUG INTERACTIONS; DRUGS, CHINESE HERBAL; MALE; MICROSOMES, LIVER; RATS; RATS, WISTAR; TESTOSTERONE;

EID: 70350075087     PISSN: 10015302     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (16)

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