Loss of heterozygosity combined with promoter hypermethylation, the main mechanism of human MutL Homolog (hMLH1) gene inactivation in non-small cell lung cancer in a Chinese population

Tumori

Volumn 95, Issue 4, 2009, Pages 488-494

  Xin, Geng ^a   Fei, Wang ^a   Liang, Zhang ^b   Wei, Ming Zhang ^a  

^a TIANJIN MEDICAL UNIVERSITY   (China)

^b TIANJIN FIFTH CENTRAL HOSPITAL   (China)

Author keywords

hMLH1; Loss of heterozygosity; Lung cancer; Methylation; NSCLC

Indexed keywords

MESSENGER RNA; PROTEIN MLH1;

ADULT; ARTICLE; CHINESE; CONTROLLED STUDY; DNA HYPERMETHYLATION; DNA METHYLATION; EPIGENETICS; FEMALE; GENE EXPRESSION; GENE FREQUENCY; GENE INACTIVATION; GENE MUTATION; HETEROZYGOSITY LOSS; HUMAN; HUMAN TISSUE; LUNG CARCINOGENESIS; LUNG NON SMALL CELL CANCER; LUNG SQUAMOUS CELL CARCINOMA; MAJOR CLINICAL STUDY; MALE; PRIMARY TUMOR; PROMOTER REGION; PROTEIN EXPRESSION;

EID: 70350061166     PISSN: 03008916     EISSN: None     Source Type: Journal    
DOI: 10.1177/030089160909500414     Document Type: Article

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