Isoform specificity of cardiac glycosides binding to human Na+,K+-ATPase α1β1, α2β1 and α3β1

European Journal of Pharmacology

Volumn 622, Issue 1-3, 2009, Pages 7-14

  Hauck, Christian ^a   Potter, Tatjana ^a   Bartz, Michaela ^b   Wittwer, Thorsten ^a   Wahlers, Thorsten ^a   Mehlhorn, Uwe ^e   Scheiner Bobis, Georgios ^b   McDonough, Alicia A ^d   Bloch, Wilhelm ^c   Schwinger, Robert H G ^f   Müller Ehmsen, Jochen ^a  

^a UNIVERSITY OF COLOGNE   (Germany)

^b JUSTUS LIEBIG UNIVERSITY   (Germany)

^c GERMAN SPORT UNIVERSITY COLOGNE   (Germany)

^d UNIVERSITY OF SOUTHERN CALIFORNIA   (United States)

^e JOHANNES GUTENBERG UNIVERSITY   (Germany)

^f Klinikum Weiden   (Germany)

Author keywords

Acetyldigoxin; Digitoxin; Digoxin; Heart failure; Methyldigoxin

Indexed keywords

ACETYLDIGOXIN; ADENOSINE TRIPHOSPHATASE (POTASSIUM SODIUM); ADENOSINE TRIPHOSPHATASE (POTASSIUM SODIUM) ALPHA1BETA1; ADENOSINE TRIPHOSPHATASE (POTASSIUM SODIUM) ALPHA2BETA1; ADENOSINE TRIPHOSPHATASE (POTASSIUM SODIUM) ALPHA3BETA1; CARDIAC GLYCOSIDE; DIGITOXIN; DIGOXIN; METILDIGOXIN; OUABAIN; POTASSIUM ION; TRITIUM; UNCLASSIFIED DRUG;

ARTICLE; BINDING AFFINITY; CELL MEMBRANE; CONTROLLED STUDY; DRUG PROTEIN BINDING; DRUG STRUCTURE; ENZYME LOCALIZATION; ENZYME SPECIFICITY; HEART FAILURE; HEART MUSCLE; HEART MUSCLE CELL; HUMAN; HUMAN CELL; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; ISOTOPE LABELING; PRIORITY JOURNAL; PROTEIN EXPRESSION; WESTERN BLOTTING;

ANIMALS; CARDIAC GLYCOSIDES; CELL MEMBRANE; H(+)-K(+)-EXCHANGING ATPASE; HEART FAILURE; HUMANS; IMMUNOHISTOCHEMISTRY; INTRACELLULAR SPACE; ISOENZYMES; MYOCYTES, CARDIAC; OUABAIN; PROTEIN BINDING; SACCHAROMYCES CEREVISIAE; SODIUM-POTASSIUM-EXCHANGING ATPASE; SUBSTRATE SPECIFICITY;

EID: 70349989868     PISSN: 00142999     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ejphar.2009.08.039     Document Type: Article

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