Some lessons from the systematic production and structural analysis of soluble αβ T-cell receptors

Journal of Immunological Methods

Volumn 350, Issue 1-2, 2009, Pages 14-21

  van Boxel, Gijs I ^a   Stewart Jones, Guillaume ^a,c   Holmes, Samantha ^a,c   Sainsbury, Sarah ^b   Shepherd, Dawn ^c   Gillespie, G M A ^c   Harlos, Karl ^a,b   Stuart, David I ^b   Owens, Ray ^b   Jones, E Yvonne ^a,b  

^a IMPERIAL CANCER RESEARCH FUND   (United Kingdom)

^b Division of Structural Biology   (United Kingdom)

^c UNIVERSITY OF OXFORD   (United Kingdom)

Author keywords

Cellular immune response; Crystallization; High throughput; Protein expression; Refolding

Indexed keywords

T LYMPHOCYTE RECEPTOR ALPHA CHAIN; T LYMPHOCYTE RECEPTOR BETA CHAIN;

CONTROLLED STUDY; CRYSTALLIZATION; MAJOR HISTOCOMPATIBILITY COMPLEX; MOLECULAR CLONING; NONHUMAN; PRIORITY JOURNAL; PROTEIN DATABASE; PROTEIN EXPRESSION; PROTEIN FOLDING; PROTEIN PURIFICATION; PROTEIN STRUCTURE; PROTEIN SYNTHESIS; QUALITY CONTROL; REVIEW; ROBOTICS; X RAY CRYSTALLOGRAPHY;

ANIMALS; CRYSTALLOGRAPHY, X-RAY; HISTOCOMPATIBILITY ANTIGENS; HUMANS; PROTEIN STRUCTURE, QUATERNARY; RECEPTORS, ANTIGEN, T-CELL, ALPHA-BETA; SOLUBILITY;

EID: 70349973747     PISSN: 00221759     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jim.2009.08.008     Document Type: Review

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