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Volumn 5, Issue 10, 2009, Pages 529-530

Inflammation: Canakinumab for the cryopyrin-associated periodic syndromes

Author keywords

[No Author keywords available]

Indexed keywords

CANAKINUMAB; CRYOPYRIN; ILARIS; INTERLEUKIN 1; INTERLEUKIN 1BETA; MONOCLONAL ANTIBODY; PLACEBO; RECOMBINANT INTERLEUKIN 1 RECEPTOR BLOCKING AGENT; RILONACEPT; UNCLASSIFIED DRUG;

EID: 70349966204     PISSN: 17594790     EISSN: 17594804     Source Type: Journal    
DOI: 10.1038/nrrheum.2009.195     Document Type: Article
Times cited : (14)

References (7)
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    • NALP3 forms an Il-1β-processing inflammasome with increased activity in Muckle-Wells autoinflammatory disorder
    • Agostini, L. et al. NALP3 forms an Il-1β-processing inflammasome with increased activity in Muckle-Wells autoinflammatory disorder. Immunity 30, 319-325 (2004).
    • (2004) Immunity , vol.30 , pp. 319-325
    • Agostini, L.1
  • 3
    • 33746876396 scopus 로고    scopus 로고
    • Neonatal-onset multisystem inflammatory disease responsive to interleukin-1β inhibition
    • Mansky-Goldbach, R. et al. Neonatal-onset multisystem inflammatory disease responsive to interleukin-1β inhibition. N. Engl. J. Med. 355, 581-592 (2006).
    • (2006) N. Engl. J. Med , vol.355 , pp. 581-592
    • Mansky-Goldbach, R.1
  • 4
    • 66649102432 scopus 로고    scopus 로고
    • Use of canakinumab in the cryopyrin-associated periodic syndrome
    • Lachmann, H. J. et al. Use of canakinumab in the cryopyrin-associated periodic syndrome. N. Engl. J. Med. 360, 2416-2425 (2009).
    • (2009) N. Engl. J. Med , vol.360 , pp. 2416-2425
    • Lachmann, H.J.1
  • 5
    • 66049094734 scopus 로고    scopus 로고
    • In vivo regulation of interleukin 1β in patients with cryopyrin-associated periodic syndromes
    • Lachmann, H. J. et al. In vivo regulation of interleukin 1β in patients with cryopyrin-associated periodic syndromes. J. Exp. Med. 206, 1029-1036 (2009).
    • (2009) J. Exp. Med , vol.206 , pp. 1029-1036
    • Lachmann, H.J.1
  • 6
    • 49449094179 scopus 로고    scopus 로고
    • Efficacy and safety of rilonacept (interleukin-1 Trap) in patients with cryopyrin-associated periodic syndromes: Results from two sequential placebo-controlled studies
    • Hoffman, H. M. et al. Efficacy and safety of rilonacept (interleukin-1 Trap) in patients with cryopyrin-associated periodic syndromes: results from two sequential placebo-controlled studies. Arthritis Rheum. 58, 2443-2452 (2008).
    • (2008) Arthritis Rheum , vol.58 , pp. 2443-2452
    • Hoffman, H.M.1
  • 7
    • 70349919091 scopus 로고    scopus 로고
    • A phase II trial with canakinumab (ACZ885), A new IL-1β blocking monoclonal antibody to evaluate the safety and preliminary efficacy in children with systemic juvenile idiopathic arthritis [abstract OP-0298]
    • Ruperto, N. et al. A phase II trial with canakinumab (ACZ885), A new IL-1β blocking monoclonal antibody to evaluate the safety and preliminary efficacy in children with systemic juvenile idiopathic arthritis [abstract OP-0298]. Arthritis Rheum. 68 (Suppl. 3), 170-171 (2009).
    • (2009) Arthritis Rheum , vol.68 , Issue.SUPPL. 3 , pp. 170-171
    • Ruperto, N.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.