Overexpression of degenerative spermatocyte homolog 1 up-regulates the expression of cyclin D1 and enhances metastatic efficiency in esophageal carcinoma Eca109 cells

Molecular Carcinogenesis

Volumn 48, Issue 10, 2009, Pages 886-894

  Zhou, Wu ^a   Ye, Xiao Lei ^b   Sun, Zhi Jian ^c   Ji, Xiao Dan ^c   Chen, Hai Xiang ^a   Xie, Dong ^c  

^a ZHEJIANG UNIVERSITY   (China)

^b CHINA PHARMACEUTICAL UNIVERSITY   (China)

^c Shanghai Jiao Tong University Affiliated Sixth People s Hospital   (China)

Author keywords

Cell cycle arrest; Cyclin D1; DEGS1; Tumor metastasis

Indexed keywords

ACYL COENZYME A DESATURASE; CYCLIN D1; DEGENERATIVE SPERMATOCYTE HOMOLOG 1; SMALL INTERFERING RNA; UNCLASSIFIED DRUG; UVOMORULIN; CADHERIN; DEGS1 PROTEIN, HUMAN; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; LUCIFERASE; MESSENGER RNA;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CANCER CELL CULTURE; CELL CYCLE REGULATION; CONTROLLED STUDY; ESOPHAGUS CARCINOMA; GENE OVEREXPRESSION; HUMAN; HUMAN CELL; METASTASIS POTENTIAL; MOUSE; NONHUMAN; NUDE MOUSE; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN INDUCTION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; RNA INTERFERENCE; TUMOR XENOGRAFT; ANIMAL; CELL CYCLE; CELL MOTION; CELL PROLIFERATION; DRUG EFFECT; ESOPHAGUS TUMOR; FLUORESCENT ANTIBODY TECHNIQUE; GENE EXPRESSION REGULATION; GENE SILENCING; GENETIC TRANSFECTION; GENETICS; METABOLISM; METASTASIS; PATHOLOGY; PHYSIOLOGY; TUMOR CELL CULTURE; UPREGULATION; WESTERN BLOTTING;

MUS MUSCULUS;

ANIMALS; BLOTTING, WESTERN; CADHERINS; CELL CYCLE; CELL MOVEMENT; CELL PROLIFERATION; CYCLIN D1; ESOPHAGEAL NEOPLASMS; FATTY ACID DESATURASES; FLUORESCENT ANTIBODY TECHNIQUE; GENE EXPRESSION REGULATION, NEOPLASTIC; GENE SILENCING; HUMANS; LUCIFERASES; MICE; MICE, NUDE; NEOPLASM METASTASIS; NF-KAPPA B; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER; RNA, SMALL INTERFERING; TRANSFECTION; TUMOR CELLS, CULTURED; UP-REGULATION;

EID: 70349949072     PISSN: 08991987     EISSN: 10982744     Source Type: Journal    
DOI: 10.1002/mc.20533     Document Type: Article

References (32)

1. Matsushime H, Roussel MF, Ashmun RA, Sherr CJ. Colonystimulating factor 1 regulates novel cyclins during the G1 phase of the cell cycle. cell 1991;65:701-713.
2. Pestell RG, Albanese C, Reutens AT, Segall JE, Lee RJ, Arnold A. The cyclins and cyclin-dependent kinase inhibitors in hormonal regulation of proliferation and differentiation. Endocr Rev 1999;20:501-534. (Pubitemid 30647078)
3. Sherr CJ, Roberts JM. CDK inhibitors: Positive and negative regulators of G1-phase progression. Genes Dev 1999;13: 1501-1512.
4. Resnitzky D, Reed SI. Different roles for cyclins D1 and E in regulation of the G1-to-S transition. Mol Cell Biol 1995;15: 3463-3469.
5. Zhao J, Pestell RG, Guan J-L. Transcriptional activation of cyclin D1 promoter by Fak contributes to cell cycle progression. Mol Biol Cell 2001;12:4066-4077. (Pubitemid 34001092)
6. D'Amico M, Hulit J, Amanatullah DF, et al. The integrinlinked kinase regulates the cyclin D1 gene through glycogen synthase kinase 3 and CREB dependent pathways. J Biol Chem 2000;275:32649-32657.
7. Bohmer RM, Scharf E, Assoian RK. Cytoskeletal integrity is required throughout the mitogen stimulation phase of the cell cycle and mediates the anchorage dependent expression of cyclin D1. Mol Biol Cell 1996;7:101-111. (Pubitemid 26033653)
8. Jares P, Fernandez PL, Campo E, et al. PRAD-1/cyclin D1 gene amplification correlates with messenger RNA overexpression and tumor progression in human laryngeal carcinomas. Cancer Res 1994;79:4813-4817.
9. Drobnjak M, Osman I, Scher HI, Fazzari M, Cordon-Cardo C. Overexpression of cyclin D1 is associated with metastatic prostate cancer to bone. Clin Cancer Res 2000;6:1891-1895. (Pubitemid 30305086)
10. Cadena DL, Kurten RC, Gill GN. The product of the MLDgene is a member of the membrane fatty acid desaturase family: Overexpression of MLD inhibits EGFR biosynthesis. Biochemistry 1997;10:6960-6967.
11. Kraveka JM, Li L, Szulc ZM, et al. Involvement of the dihydroceramide desaturase in cell cycle progression in human neuroblastoma cells. J Biol Chem 2007;282: 16718-16728. (Pubitemid 47093220)
12. Qin XF, An DS, Chen IS, Baltimore D. Inhibiting HIV-1 infection in human T cells by lentiviral-mediated delivery of small interfering RNA against CCR5. Proc Natl Acad Sci USA 2003;100:183-188.
13. Tong Q, Zheng L, Lin L, et al. VEGF is upregulated by hypoxiainduced mitogenic factor via the PI-3K/Akt-NF-κB signaling pathway. Respir Res 2006;7:37.
14. Holnthoner W, Pillinger M, Groger M, et al. Fibroblast growth factor-2 induces Lef/Tcf-dependent transcriptioninhuman endothelial cells. J Biol Chem 2002;277:45847-45853. (Pubitemid 35417563)
15. Beier F, Lee R, Taylor AC, Pestell RG, LuValle P. Identification of the cyclin D1 gene as a target of ATF-2 in chondrocytes. Proc Natl Acad Sci USA 1999;96:1433-1438.
16. Brown JR, Nigh E, Lee RJ, et al. Fos family members induce cell cycle entry by activating cyclinD1. Mol Cell Biol 1998;18:5609-5619. (Pubitemid 28388143)
17. Baldin V, Lukas J, Marcote MJ, Pagano M, Draetta G. Cyclin D1 is a nuclear protein required for cell cycle progression in G1. Genes Dev 1993;7:812-821. (Pubitemid 23163585)
18. Weinstein IB. Relevance of cyclin D1 and other molecular markers to cancer chemoprevention. J Cell Biochem Suppl 1996;25:23-28.
19. Motokura T, Bloom T, Kim HG, et al. novel cyclin encoded by a bcl1-linked candidate oncogene. Nature 1991;350:512-515. (Pubitemid 21912266)
20. Mallya SM, Arnold A. Cyclin D1 in parathyroid disease. Front Biosci 2000;5:D367-D371.
21. Arnold A, Motokura T, Bloom T, et al. The putative oncogene PRAD1 encodes a novel cyclin. Cold Spring Harb Symp Quant Biol 1991;56:93-97.
22. Hemmer S, Wasenius VM, Haglund C, et al. Deletion of 11q23 and cyclin D1 overexpression are frequent aberrations in parathyroid adenomas. Am J Pathol 2001;158:1355-1362. (Pubitemid 32281299)
23. Vasef MA, Brynes RK, Sturm M, Bromley C, Robinson RA. Expression of cyclin D1 in parathyroid carcinomas, adenomas, and hyperplasias: A paraffin immunohistochemical study. Mod Pathol 1999;12:412-416. (Pubitemid 29203331)
24. Tominaga Y, Tsuzuki T, Uchida K, et al. Expression of PRAD1/cyclin D1, retinoblastoma gene products, and Ki67 in parathyroid hyperplasia caused by chronic renal failure versus primary adenoma. Kidney Int 1999;55: 1375-1383. (Pubitemid 29157136)
25. Hsi ED, Zukerberg LR, Yang W, Arnold A. Cyclin D1/PRAD1 expression in parathyroid adenomas: An immunohistochemical study. J Clin Endocrinol Metab 1996;81:1736-1739. (Pubitemid 26152455)
26. Omae F, Miyazaki M, Enomoto A, Suzuki M, Suzuki Y, Suzuki A. DES2 protein is responsible for phytoceramide biosynthesis in the mouse small intestine. Biochem J 2004;379:687-695. (Pubitemid 38703653)
27. Halib NA, Wood CB, Apostolob K, et al. Reduction in the stearic to oleic acid ratio in humanmalignant liver neoplasms. Eur J Surg Oncol 1985;11:347-348.
28. Habib NA, Wood CB, Apostolov K, et al. Stearic acid and carcinogenesis. Br J Cancer 1987;56:455-458.
29. Dunbar LM, Bailey MJ. Enzyme deletion and essential fatty acid metabolism in cultured cells. J Biol Chem 1975;250:1152.
30. Colquhoun A, Curi R. Effects of saturated and polyunsaturated fatty acids on human tumor-cell proliferation. Gen Pharmacol 1998;30:191-194. (Pubitemid 28026720)
31. Dbaibo GS, Pushkareva MY, Jayadev S, et al. Retinoblastoma gene product as a downstream target for a ceramidedependent pathway of growth arrest. Proc Natl Acad Sci USA 1995;92:1347-1351.
32. Jayadev S, Liu B, Bielawska AE, et al. Role for ceramide in cell cycle arrest. J Biol Chem 1995;270:2047-2052.