Use of antibiotic cement-impregnated intramedullary nail in treatment of infected non-union of long bone

Indian Journal of Orthopaedics

Volumn 43, Issue 4, 2009, Pages 396-402

  Shyam, Ashok K ^a   Sancheti, Parag K ^a   Patel, Salim K ^a   Rocha, Steve ^a   Pradhan, Chetan ^a   Patil, Atul ^a  

^a Sancheti Institute for Orthopaedics and Rehabilitation   (India)

Author keywords

Antibiotic cement impregnated intramedullary nail; Bone defect; Infected non union

Indexed keywords

EID: 70349929526     PISSN: 00195413     EISSN: 19983727     Source Type: Journal    
DOI: 10.4103/0019-5413.55468     Document Type: Article

References (39)

1. Toh CL, Jupiter JB. The infected nonunion of the tibia. Clin Orthop Relat Res 1995;315:176-191
2. Court-Brown CM. Fractures of the tibia and fibula. In: Bucholz RW, Heckman JD, Court-Brown CM, editors. Rockwood and Green's fractures in adults. 6th ed. Lippincott Williams and Wilkins; 2006. p. 2080-2146
3. Patzakis MJ, Zalavras CG. Chronic posttraumatic osteomyelitis and infected nonunion of the tibia: Current management concepts. J Am Acad Orthop Surg 2005;13:417-427
4. Beals RK, Bryant RE. The treatment of chronic open osteomyelitis of the tibia in adults. Clin Orthop Relat Res 2005;433:212-217
5. Ueng SW, Chuang DC, Cheng SL, Shih CH. Management of large infected tibial defects with radical debridement and staged double-rib composite free transfer. J Trauma 1996;40:345-349
6. Chen CE, Ko JY, Wang JW, Wang CJ. Infection after intramedullary nailing of the femur. J Trauma 2002;55:338-344
7. Wu CC, Shih CH. Distal tibial nonunion treated by intramedullary reaming with external immobilization. J Orthop Trauma 1996;10:45-49
8. McKee MD, Yoo DJ, Zdero R, Dupere M, Wild L, Schemitsch EH, et al. Combined single-stage osseous and soft tissue reconstruction of the tibia with the Ilizarov method and tissue transfer. J Orthop Trauma 2008;22:183-189
9. Maini L, Chadha M, Vishwanath J, Kapoor S, Mehtani A, Dhaon BK. The Ilizarov method in infected nonunion of fractures. Injury 2000;31:509-517
10. Song HR, Cho SH, Koo KH, Jeong ST, Park YJ, Ko JH. Tibial bone defects treated by internal bone transport using the Ilizarov method. Int Orthop 1998;22:293-297
11. Dendrinos GK, Kontos S, Lyritsis E. Use of the Ilizarov technique for treatment of non-union of the tibia associated with infection. J Bone Joint Surg Am 1995;77:835-846
12. Cattaneo R, Catagni M, Johnson EE. The treatment of infected nonunions and segmental defects of the tibia by the methods of Ilizarov. Clin Orthop Rel Res 1992;280:143-152
13. Paley D, Herzenberg JE. Intramedullary infections treated with antibiotic cement rods: Preliminary results in nine cases. J Orthop Trauma 2002;16:723-729
14. Qiang Z, Jun PZ, Jie XJ, Hang L, Bing LJ, Cai LF. Use of antibiotic cement rod to treat intramedullary infection after nailing: Preliminary study in 19 patients. Arch Orthop Trauma Surg 2007;127:945-951
15. Madanagopal SG, Seligson D, Roberts CS. The antibiotic cement nail for infection after tibial nailing. Orthopedics 2004;27:709-712
16. Thonse R, Conway J. Antibiotic cement-coated interlocking nail for the treatment of infected nonunions and segmental bone defects. J Orthop Trauma 2007;21:258-268
17. Gustilo RB, Anderson JT. Prevention of infection in the treatment of one thousand and twenty-five open fractures of long bones: Retrospective and prospective analyses. J Bone Joint Surg Am 2002;84:682.
18. Cierny G, Classification and treatment of adult osteomyelitis. In: Evarts CM, editor. Surgery of the Musculoskeletal System. vol 5. New York: Churchill Livingstone; 1990. p. 4363.
19. Jain AK, Sinha S. Infected nonunion of the long bones. Clin Orthop Relat Res 2005;431:57-65.
20. Motsitsi NS. Management of infected nonunion of long bones: The last decade (1996-2006). Injury 2008;39:155-160
21. Struijs PA, Poolman RW, Bhandari M. Infected nonunion of the long bones. J Orthop Trauma 2007;21:507-511
22. Shahcheraghi GH, Bayatpoor A. Infected tibial nonunion. Can J Surg 1994;37:209-213
23. Eshima I, Feibel RJ, Louie KW, Lowenberg DW. Combined muscle flap and Ilizarov reconstruction for bone and soft tissue defects. Clin Orthop Relat Res 1996;332:37-51.
24. Donati D, Biscaglia R. The use of antibiotic-impregnated cement in infected reconstructions after resection for bone tumours. J Bone Joint Surg Br 1998;80:1045-1050
25. Zuluaga AF, Galvis W, Jaimes F, Vesga O. Lack of microbiological concordance between bone and non-bone specimens in chronic osteomyelitis: An observational study. BMC Infect Dis 2002;16:2-8.
26. Akinyoola AL, Adegbehingbe OO, Aboderin AO. Therapeutic decision in chronic osteomyelitis: Sinus track culture versus intraoperative bone culture. Arch Orthop Trauma Surg 2009;129:449-453
27. Petrisor B, Anderson S, Court-Brown CM. Infection after reamed intramedullary nailing of the tibia: A case series review. J Orthop Trauma 2005;19:437-441
28. Coles CP, Gross M. Closed tibial shaft fractures: Management and treatment complications: A review of the prospective literature. Can J Surg 2000;43:256-262
29. Joshi D, Ahmed A, Krishna L, Lal Y. Unreamed interlocking nailing in open fractures of tibia. J Orthop Surg (Hong Kong) 2004;12:216-221
30. May JW Jr, Jupiter JB, Weiland AJ, Byrd HS. Clinical classification of post-traumatic tibial osteomyelitis. J Bone Joint Surg Am 1989;71:1422-1428
31. Wininger DA, Fass RJ. Antibiotic-impregnated cement and beads for orthopedic infections. Antimicrob Agents Chemother 1996;40:2675-2679
32. Buchholz HW, Elson RA, Heinert K. Antibiotic-loaded acrylic cement: Current concepts. Clin Orthop Relat Res 1984;190:96-108.
33. Zalavras CG, Patzakis MJ, Holtom P. Local antibiotic therapy in the treatment of open fractures and osteomyelitis. Clin Orthop Relat Res 2004;427:86-93.
34. Springer BD, Lee GC, Osmon D, Haidukewych GJ, Hanssen AD, Jacofsky DJ. Systemic safety of high-dose antibiotic-loaded cement spacers after resection of an infected total knee arthroplasty. Clin Orthop Relat Res 2004;427:47-51.
35. Koo KH, Yang JW, Cho SH, Song HR, Park HB, Ha YC, et al. Impregnation of vancomycin, gentamicin, and cefotaxime in a cement spacer for two-stage cementless reconstruction in infected total hip arthroplasty. J Arthroplasty 2001;16:882-892
36. Gallo J, Kolár M, Florschütz AV, NovotnÝ R, Pantùcek R, Kesselová M. In vitro testing of gentamicin-vancomycin loaded bone cement to prevent prosthetic joint infection. Biomed Pap Med Fac Univ Palacky Olomouc Czech Repub 2005;149:153-158
37. Klemm KW. Antibiotic bead chains. Clin Orthop Relat Res 1993;295:63-76.
38. Patzakis MJ, Wilkins J, Wiss DA. Infection following intramedullary nailing of long bones: diagnosis and management. Clin Orthop Relat Res 1986;212:182-191
39. Babhulkar S, Pande K, Babhulkar S. Nonunion of the diaphysis of long bones. Clin Orthop Relat Res 2005;431:50-56