A regulatory domain spanning the repeat sequence RE1 from herpes simplex virus type 1 has cell specific differential functions in trigeminal neurons and fibroblasts

FEBS Letters

Volumn 583, Issue 20, 2009, Pages 3335-3338

  Stevens, Hannah C ^a   Fiskerstrand, Carolyn ^b   Bubb, Vivien J ^a   Dalziel, Robert ^b   Quinn, John P ^a  

^a HACB   (United Kingdom)

^b UNIVERSITY OF EDINBURGH   (United Kingdom)

Author keywords

CCCTC binding protein; Cell specific enhancer; Herpes simplex virus type 1; Tandem repeat

Indexed keywords

CCCTC BINDING PROTEIN; TRANSCRIPTION FACTOR; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; CONTROLLED STUDY; FIBROBLAST; GENE EXPRESSION REGULATION; HERPES SIMPLEX VIRUS 1; HUMAN; HUMAN CELL; KIDNEY CELL; LATENT VIRUS INFECTION; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; TANDEM REPEAT; TRANSCRIPTION REGULATION; TRANSIENT EXPRESSION; TRIGEMINUS GANGLION; VIRUS GENOME; VIRUS REACTIVATION; VIRUS TRANSCRIPTION;

ANIMALS; BASE SEQUENCE; CELLS, CULTURED; CRICETINAE; CRICETULUS; FIBROBLASTS; GENES, REPORTER; GENOME, VIRAL; HERPESVIRUS 1, HUMAN; MOLECULAR SEQUENCE DATA; NEURONS; RATS; RATS, WISTAR; REGULATORY SEQUENCES, NUCLEIC ACID; REPETITIVE SEQUENCES, NUCLEIC ACID; REPRESSOR PROTEINS; TRIGEMINAL GANGLION; VIRUS ACTIVATION;

CRICETINAE; HUMAN HERPESVIRUS 1; RATTUS;

EID: 70349928632     PISSN: 00145793     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.febslet.2009.09.037     Document Type: Article

References (23)

1. Breen, G., Collier, D., Craig, I. and Quinn, J. (2008) Variable number tandem repeats as agents of functional regulation in the genome. IEEE Eng. Med. Biol. Mag. 27, 103-104, 108.
2. Haddley K., Vasiliou A.S., Ali F.R., Paredes U.M., Bubb V.J., and Quinn J.P. Molecular genetics of monoamine transporters: relevance to brain disorders. Neurochem. Res. 33 (2008) 652-667
3. Klenova E., et al. YB-1 and CTCF differentially regulate the 5-HTT polymorphic intron 2 enhancer which predisposes to a variety of neurological disorders. J. Neurosci. 24 (2004) 5966-5973
4. Roberts J., Scott A.C., Howard M.R., Breen G., Bubb V.J., Klenova E., and Quinn J.P. Differential regulation of the serotonin transporter gene by lithium is mediated by transcription factors, CCCTC binding protein and Y-box binding protein 1, through the polymorphic intron 2 variable number tandem repeat. J. Neurosci. 27 (2007) 2793-2801
5. Matsumoto K., Nagata K., Hanaoka F., and Ui M. Tissue-specific DNA binding of nuclear proteins that bind to the adenovirus inverted terminal repeat. J. Biochem. 105 (1989) 927-932
6. Fiskerstrand C.E., Lovejoy E., Gerrard L., and Quinn J.P. An intronic domain within the rat preprotachykinin-A gene containing a CCCT repetitive motif acts as an enhancer in differentiating embryonic stem cells. Neurosci. Lett. 263 (1999) 141-144
7. Cuello A.C., Priestley J.V., and Matthews M.R. Localization of substance P in neuronal pathways. Ciba Found. Symp. (1982) 55-83
8. Nesburn A.B., Dickinson R., and Radnoti M. The effect of trigeminal nerve and ganglion manipulation on recurrence of ocular herpes simplex in rabbits. Invest. Ophthalmol. 15 (1976) 726-731
9. Yamaguchi T., Yamashita Y., Kasamo K., Inoue M., Sakaoka H., and Fujinaga K. Genomic heterogeneity maps to tandem repeat sequences in the herpes simplex virus type 2 UL region. Virus Res. 55 (1998) 221-231
10. Gu W., Huang Q., and Hayward G.S. Multiple tandemly repeated binding sites for the YY1 repressor and transcription factors AP-1 and SP-1 are clustered within Intron-1 of the gene encoding the IE110 transactivator of herpes simplex virus type 1. J. Biomed. Sci 2 (1995) 203-226
11. Norberg P., Liljeqvist J.A., Bergstrom T., Sammons S., Schmid D.S., and Loparev V.N. Complete-genome phylogenetic approach to varicella-zoster virus evolution: genetic divergence and evidence for recombination. J. Virol. 80 (2006) 9569-9576
12. Perry L.J., and McGeoch D.J. The DNA sequences of the long repeat region and adjoining parts of the long unique region in the genome of herpes simplex virus type 1. J. Gen. Virol. 69 Pt 11 (1988) 2831-2846
13. Amelio A.L., McAnany P.K., and Bloom D.C. A chromatin insulator-like element in the herpes simplex virus type 1 latency-associated transcript region binds CCCTC-binding factor and displays enhancer-blocking and silencing activities. J. Virol. 80 (2006) 2358-2368
14. Lobanenkov V.V., Nicolas R.H., Adler V.V., Paterson H., Klenova E.M., Polotskaja A.V., and Goodwin G.H. A novel sequence-specific DNA binding protein which interacts with three regularly spaced direct repeats of the CCCTC-motif in the 5′-flanking sequence of the chicken c-myc gene. Oncogene 5 (1990) 1743-1753
15. Durham P.L., and Russo A.F. Stimulation of the calcitonin gene-related peptide enhancer by mitogen-activated protein kinases and repression by an antimigraine drug in trigeminal ganglia neurons. J. Neurosci. 23 (2003) 807-815
16. Li, T. and Lu, L. (2007) Functional role of CCCTC binding factor (CTCF) in stress-induced apoptosis. Exp. Cell Res.
17. Li T., Lu Z., and Lu L. Pax6 regulation in retinal cells by CCCTC binding factor. Invest. Ophthalmol. Vis. Sci. 47 (2006) 5218-5226
18. Klenova E.M., Nicolas R.H., U S., Carne A.F., Lee R.E., Lobanenkov V.V., and Goodwin G.H. Molecular weight abnormalities of the CTCF transcription factor: CTCF migrates aberrantly in SDS-PAGE and the size of the expressed protein is affected by the UTRs and sequences within the coding region of the CTCF gene. Nucl. Acids Res. 25 (1997) 466-474
19. Smith, S.T. et al. (2009) Genome wide ChIP-chip analyses reveal important roles for CTCF in Drosophila genome organization. Dev. Biol.
20. Amelio A.L., Giordani N.V., Kubat N.J., O'Neil J.E., and Bloom D.C. Deacetylation of the herpes simplex virus type 1 latency-associated transcript (LAT) enhancer and a decrease in LAT abundance precede an increase in ICP0 transcriptional permissiveness at early times postexplant. J. Virol. 80 (2006) 2063-2068
21. Chen Q., Lin L., Smith S., Huang J., Berger S.L., and Zhou J. CTCF-dependent chromatin boundary element between the latency-associated transcript and ICP0 promoters in the herpes simplex virus type 1 genome. J. Virol. 81 (2007) 5192-5201
22. Stedman W., Kang H., Lin S., Kissil J.L., Bartolomei M.S., and Lieberman P.M. Cohesins localize with CTCF at the KSHV latency control region and at cellular c-myc and H19/Igf2 insulators. Embo J. 27 (2008) 654-666
23. Quinn J.P., McGregor R.A., Fiskerstrand C.E., Davey C., Allan J., and Dalziel R.G. Identification of a novel multifunctional structural domain in the herpes simplex virus type 1 genome: implications for virus latency. J. Gen. Virol. 79 Pt 10 (1998) 2529-2532