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Volumn 48, Issue 40, 2009, Pages 7436-7439

Palladium-catalyzed cross-coupling of aryl halides using organotitanium nucleophiles

Author keywords

Cross coupling; Palladium; Phosphanes; Sulfones; Titanium

Indexed keywords

ARYL HALIDES; CATALYST LOADINGS; CROSS-COUPLING; MILD REACTION CONDITIONS; PALLADIUM-CATALYZED CROSS-COUPLINGS; PHOSPHANES; SULFONES; SULFONYL CHLORIDES; TITANIUM REAGENT;

EID: 70349911457     PISSN: 14337851     EISSN: None     Source Type: Journal    
DOI: 10.1002/anie.200904033     Document Type: Article
Times cited : (69)

References (55)
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    • There is only one reported example with an aryl triflate (Ref. [13]). In fact, no examples of the use of aryl halides and aryl titanium reagents in palladium-catalyzed Ar-Ar′ coupling reactions have been reported so far
    • There is only one reported example with an aryl triflate (Ref. [13]). In fact, no examples of the use of aryl halides and aryl titanium reagents in palladium-catalyzed Ar-Ar′ coupling reactions have been reported so far.
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    • For our recent study on aminophosphanes based on an indolyl scaffold
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    • Pd black was observed after heating the reaction for about 10 minutes
    • Pd black was observed after heating the reaction for about 10 minutes.
  • 52
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    • 3P ligand resulted in 29% conversion of ArCl and a 26% yield of the desired product (GC yield)
    • 3P ligand resulted in 29% conversion of ArCl and a 26% yield of the desired product (GC yield).


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