Induction of DNA strand breaks, base lesions and clustered damage sites in hydrated plasmid DNA films by ultrasoft X rays around the phosphorus k edge

Radiation Research

Volumn 172, Issue 3, 2009, Pages 296-305

  Yokoya, Akinari ^a   Cunniffe, Siobhan M T ^b   Watanabe, Ritsuko ^a   Kobayashi, Katsumi ^c   O'Neill, Peter ^b  

^a JAPAN ATOMIC ENERGY AGENCY   (Japan)

^b UNIVERSITY OF OXFORD   (United Kingdom)

^c HIGH ENERGY ACCELERATOR RESEARCH ORGANIZATION KEK   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

DNA BASE; DNA FORMAMIDOPYRIMIDINE GLYCOSYLASE; ENDONUCLEASE; PHOSPHORUS; PLASMID DNA; POTASSIUM; DNA; WATER;

ARTICLE; DNA DAMAGE; DNA STRAND BREAKAGE; DOSE RESPONSE; DOUBLE STRANDED DNA BREAK; ENZYME INDUCTION; EXCISION REPAIR; GAMMA RADIATION; GEL ELECTROPHORESIS; HYDRATION; MOLECULAR INTERACTION; NONHUMAN; PRIORITY JOURNAL; SINGLE STRANDED DNA BREAK; X IRRADIATION; CHEMICAL MODEL; CHEMICAL STRUCTURE; CHEMISTRY; COMPUTER SIMULATION; CONFORMATION; PLASMID; RADIATION DOSE; RADIATION EXPOSURE; RADIATION RESPONSE; SOLUTION AND SOLUBILITY; ULTRASTRUCTURE; X RAY;

COMPUTER SIMULATION; DNA; DNA DAMAGE; DOSE-RESPONSE RELATIONSHIP, RADIATION; MODELS, CHEMICAL; MODELS, MOLECULAR; NUCLEIC ACID CONFORMATION; PHOSPHORUS; PLASMIDS; RADIATION DOSAGE; SOLUTIONS; WATER; X-RAYS;

EID: 70349909702     PISSN: 00337587     EISSN: None     Source Type: Journal    
DOI: 10.1667/RR1609.1     Document Type: Article

References (52)

1. D. T. Goodhead, Soft X-ray radiobiology and synchrotron radiation. In Synchrotron Radiation in the Biosciences (B. Chance, J. Deisenhofer, S. Ebashi, D. T. Goodhead, J. R. Helliwell, H. E. Huxley, T. Iizuka, J. Kirz, T. Mitsui, E. Rubenstein, N. Stuhrmann, K. Wüthrich and G. Zaccai, Eds.), pp. 683-705. Oxford University Press, Oxford, 1994.
2. H. Nikjoo and D. T. Goodhead, Track structure analysis illustrating the prominent role of low-energy electrons in radiobiological effects of low-LET radiations. Phys. Med. Biol. 36, 229-238 (1991).
3. C. M. deLara, M. A. Hill, T. J. Jenner, D. Papworth and P. O'Neill, Dependence of the yields on DNA double-strand breaks in Chinese hamster V79-4 cells on the photon energy of ultrasoft X rays. Radiat. Res. 155, 440-448 (2001).
4. D. Frankenberg, D. T. Goodhead, M. Frankenberg-Schwager, R. Harbich, D. A. Bance and R. E. Wilkinson, Effectiveness of 1.5 keV aluminium and 0.3 keV carbon K characteristic x-rays at inducing DNA double-strand breaks in yeast cells. Int. J. Radiat. Biol. 50, 727-741 (1986).
5. M. R. Raju, S. G. Carpenter, J. J. Chmielewski, M. E. Schillaci, M. E. Wilder, J. P. Freyer, N. F. Johnson, P. L. Schor, R. J. Sebring and D. T. Goodhead, Radiobiology of ultrasoft X rays I. Cultured hamster cells (V79). Radiat. Res. 110, 396-412 (1987).
6. D. J. Brenner, R. P. Bird, M. Zaider, P. Goldhagen, P. J. Kliaga and H. H. Rossi, Inactivation of synchronized mammalian cells with low energy X rays - results and significance. Radiat. Res. 110, 413-427 (1987).
7. M. Folkard, B. Vojnovic, K. M. Prise and B. D. Michael, An arrangement for irradiating cultured mammalian cells with aluminium characteristic ultrasoft X-rays. Phys. Med. Biol. 32, 1615-1626 (1987).
8. K. M. Prise, M. Folkard, S. Davies and B. D. Michael, Measurements of DNA damage and cell killing in Chinese hamster V79-4 cells irradiated with aluminum characteristic ultrasoft X rays. Radiat. Res. 117, 489-499 (1989).
9. S. W. Botchway, D. L. Stevens, M. A. Hill, T. J. Jenner and P. O'Neill, Induction and rejoining of DNA double strand breaks in Chinese hamster V79-4 cells with characteristic aluminum K and copper L ultrasoft X rays. Radiat. Res. 148, 317-324 (1997).
10. D. T. Goodhead and H. Nikjoo, Current status of ultrasoft X rays and track structure analysis as tools for testing and developing biophysical models of radiation action. Radiat. Prot. Dosimetry 31, 343-350 (1990).
11. K X-rays. Int. J. Radiat. Biol. 38, 545-557 (1980).
12. R. E. Wilkinson, D. T. Goodhead and J. Thacker, Induction of chromosome aberrations by very short tracks at different stages of the cell cycle. Radiat. Prot. Dosimetry 13, 161-165 (1985).
13. J. Thacker, R. E. Wilkinson and D. T. Goodhead, The induction of chromosome exchange aberrations by carbon ultrasoft X-rays in V79 hamster cells. Int. J. Radiat. Biol. 49, 645-656 (1986).
14. M. S. Sasaki, Primary damage and fixation of chromosomal DNA as probed by monochromatic soft X-rays and low-energy neutrons. In The Early Effects of Radiation on DNA (E. M. Fielden and P. O'Neill, Eds.), pp. 369-384. Springer-Verlag, Berlin, 1991.
15. K X rays are efficient producers of complex chromosome exchange aberrations as revealed by fluorescence in situ hybridization. Radiat. Res. 146, 144-150 (1996).
16. C. S. Griffin, M. A. Hill, D. G. Popworth, K. M. S. Townsend, J. R. K. Savage and D. T. Goodhead, Effectiveness of 0.28 keV carbon K ultrasoft X-rays at producing simple and complex chromosome exchanges in human fibroblasts in vitro detected using FISH. Int. J. Radiat. Biol. 73, 591-598 (1998).
17. K X-rays and α-particles: comparison of experimental and simulated yields. Int. J. Radiat. Biol. 77, 1053-1066 (2001).
18. S. M. T. Cunniffe and P. O'Neill, The complexity of radiation-induced DNA damage as revealed by exposure to cell extracts. Radiat. Res. 152, 421-427 (1999).
19. P. Bernhardt, W. Friedland, R. Mackbach, P. Jacob and H. G. Paretzke, Monte Carlo simulation of DNA damage by low LET radiation using inhomogeneous higher order DNA targets. Radiat. Prot. Dosimetry 99, 203-205 (2002).
20. K. Hieda, T. Hirono, A. Azami, M. Suzuki, Y. Furusawa, H. Maezawa, N. Usami, A. Yokoya and K. Kobayashi, Single- and double-strand breaks in pBR322 plasmid DNA by monochromatic X-rays on and off the K-absorption peak of phosphorus. Int. J. Radiat. Biol. 70, 437-445 (1996).
21. A. Yokoya, R. Watanabe and T. Hara, Single- and double-strand breaks in solid pBR322 DNA induced by ultrasoft X-rays at photon energies of 388, 435 and 573 eV. J. Radiat. Res. 40, 145-158 (1999).
22. B. Fayard, A. Touati, F. Abel, M. A. Herve du Penhoat, I. Despiney-Bailly, F. Gobert, M. Ricoul, A. L'Hoir, M. F. Politis and A. Chetioui, Cell inactivation and double-strand breaks: The role of core ionization, as probed by ultrasoft X rays. Radiat. Res. 157, 128-140 (2002).
23. A. Eschenbrenner, M. A. Herve Du Penhoat, A. Boissiere, G. Eot-Houllier, F. Abel, M. F. Politis, A. Touati, E. Sage and A. Chetioui, Strand breaks induced in plasmid DNA by ultrasoft X-rays: influence of hydration and packing. Int. J. Radiat. Biol. 83, 687-697 (2007).
24. K. Hieda and T. Ito, Radiobiological experiments in the X-ray region with synchrotron radiation. In Handbook on Synchrotron Radiation (S. Ebashi, M. Koch and E. Rubenstein, Eds.), Vol. 4, pp. 431-466. North-Holland, Amsterdam, 1991.
25. K. Kobayashi, K. Hieda, H. Maezawa, Y. Furusawa, M. Suzuki and T. Ito, Effects of K-shell X-ray absorption of intracellular phosphorus on yeast cells. Int. J. Radiat. Biol. 59, 634-650 (1991).
26. M. Watanabe, M. Suzuki, K. Watanabe, K. Suzuki, N. Usami, A. Yokoya and K. Kobayashi, Mutagenic and transforming effects of soft-X-rays with resonance energy of phosphorus Kabsorption edge. Int. J. Radiat. Biol. 61, 161-168 (1992).
27. H. Maezawa, Y. Furusawa, K. Kobayashi, K. Hieda, M. Suzuki, N. Usami, A. Yokoya and T. Mori, Lethal effect of K-shell absorption of intracellular phosphorus on wild-type and radiation sensitive mutants of Escherichia coli. Acta Oncol. 35, 889-894 (1996).
28. N. Usami, A. Yokoya, S. Ishizaka and K. Kobayashi, Reparability of lethal lesions produced by phosphorus photoabsorption in yeast cells. J. Radiat. Res. 42, 317-331 (2001).
29. S. Saigusa, Y. Ejima, K. Kobayashi and M. S. Sasaki, Induction of chromosome aberrations by monochromatic X-rays with resonance energy of phosphorus K-shell absorption edge. Int. J. Radiat. Biol. 61, 785-790 (1992).
30. C. Le Sech, H. Frohlich, C. Saint-Marc and M. Charlier, DNA breakage upon K-shell excitation of phosphorus as a model for direct effects in radiation biology. Radiat. Res. 145, 632-6325 (1996).
31. T. Ito, M. Saito and K. Kobayashi, Dissociation of a model DNA compound dApdA by monochromatic soft X-rays in solids and comments on the high selectivity for 3′ breakage in the phosphoester bond. Int. J. Radiat. Biol. 62, 129-36 (1992).
32. K. Takakura, H. Maezawa, K. Kobayashi and K. Hieda, Strand breaks in DNA in buffered solution induced by monochromatic X-rays around the K-shell absorption edge of phosphorus. In Synchrotron Radiation in the Biosciences (B. Chance, J. Deisenhofer, S. Ebashi, D. T. Goodhead, J. R. Helliwell, H. E. Huxley, T. Iizuka, J. Kirz, T. Mitsui, E. Rubenstein, N. Stuhrmann, K. Wüthrich and G. Zaccai, Eds.), pp. 683-705. Oxford University Press, Oxford, 1994.
33. H. Nikjoo, P. O'Neill, M. Terrissol and D. T. Goodhead, Quantitative modelling of DNA damage using Monte Carlo track structure method. Radiat. Environ. Biophys. 38, 31-38 (1999).
34. A. Yokoya, C. M. T. Cunniffe and P. O'Neill, Effect of hydration on the induction of strand breaks and base lesions in plasmid DNA films by gamma-radiation. J. Am. Chem. Soc. 124, 8859-8866 (2002).
35. J. T. Lett, Cellular radiation biology in consolidation and transition. Br. J. Cancer 55, 145-152 (1987).
36. M. Falk, K. A. Hartman and R. C. Lord, Hydration of deoxyribonucleic acid. II. An infrared study. J. Am. Chem. Soc. 85, 387-391 (1963).
37. M. T. Milano and W. A. Bernhard, The influence of packing on free radical yields in solid-state DNA: film compared to lyophilized frozen solution. Radiat. Res. 152, 196-201 (1999).
38. N. J. Tao, S. M. Lindsay and A. Rupprecht, Structure of DNA hydration shells studied by Raman spectroscopy. Biopolymers 28, 1019-1030 (1989).
39. H. Konishi, A. Yokoya, H. Shiwaku, H. Motohashi, T. Makita, Y. Kashihara, S. Hashimoto, T. Harami, T. A. Sasaki and K. Kobayashi, Synchrotron radiation beamline to study radioactive materials at the Photon Factory. Nucl. Instrum. Methods A372, 322-332 (1996).
40. R. Watanabe, N. Usami and K. Kobayashi, Oxidation yield of the ferrous ion in a Fricke solution irradiated with monochromatic synchrotron soft X-rays in the 1.8-10 keV region. Int. J. Radiat. Biol. 68, 113-120 (1995).
41. K. Kobayashi, K. Hieda, H. Maezawa, M. Ando and T. Ito, Monochromatic X-ray irradiation system (0.08-0.4 nm) for radiation biology studies using synchrotron radiation at the photon factory. J. Radiat. Res. 28, 243-53 (1987).
42. H. Asahara, P. M. Wistort, J. F. Bank, R. H. Bakerian and R. P. Cunningham, Purification and characterization of Escherichia coli endonuclease III from the cloned nth gene. Biochemistry 28, 4444-4449 (1989).
43. T. Melvin, S. M. T. Cunniffe, P. O'Neill, A. W. Parker and T. Roldan-Aujona, Guanine is the target for direct ionisation damage in DNA, as detected using excision enzymes. Nucleic Acids Res. 26, 4935-4942 (1998).
44. P. S. Hodgkins, M. P. Fairman and P. O'Neill, Rejoining of gamma-radiation-induced single-strand breaks in plasmid DNA by human cell extracts: dependence on the concentration of the hydroxyl radical scavenger, Tris. Radiat. Res. 145, 24-30 (1996).
45. J. R. Milligan, A. D. Arnold and J. F. Ward, The effect of superhelical density on the yield of single-strand breaks in gamma-irradiated plasmid DNA. Radiat. Res. 132, 69-73 (1992).
46. A. Yokoya, C. M. T. Cunniffe, D. L. Stevens and P. O'Neill, Effect of hydration on the induction of strand breaks, base lesions and clustered damage in DNA films by α-radiation. J. Phys. Chem. 124, 832-837 (2003).
47. T. Ito, S. C. Backer, C. D. Stickley, J. D. Peak and M. J. Peak, Dependence of the yield of strand breaks induced by gamma-rays in DNA on the physical conditions of exposure: water content and temperature. Int. J. Radiat. Biol. 63, 289-296 (1993).
48. R. Watanabe, A. Yokoya, K. Fujii and K. Saito, DNA strand breaks by direct energy deposition by Auger and photo-electrons ejected from DNA constituent atoms following K-shell photoabsorption. Int. J. Radiat. Biol. 80, 823-32 (2004).
49. 2+ ion irradiation. Int. J. Radiat. Biol. 84, 23-33 (2008).
50. J. H. Hubbell, Photon mass attenuation and energy-absorption coefficients from 1 keV to 20 MeV. Int. J. Appl. Radiat. Isot. 33, 1269-1290 (1982). [Available online at http://physics.nist.gov/PhysRefData/XrayMassCoef/ ComTab/air.html].
51. ICRU, Average Energy Required to Produce an Ion Pair. Report No. 31, International Commission on Radiation Units and Measurements, 1979.
52. B. L. Henke, E. M. Gullikson and J. C. Davis, X-ray interactions: Photoabsorption, scattering, transmission and reflection at E = 50 to 30000 eV, Z = 1 to 92. At. Data Nucl. Data Tables 54, 181-342 (1993). [Available online at http://www-cxro.lbl.gov/opticalconstants/ pertform.html]