Vaccination with Mage-b DNA induces CD8 T-cell responses at young but not old age in mice with metastatic breast cancer

British Journal of Cancer

Volumn 101, Issue 8, 2009, Pages 1329-1337

  Castro, F ^a   Leal, B ^b   Denny, A ^b   Bahar, R ^c   Lampkin, S ^c   Reddick, R ^c   Lu, S ^a   Gravekamp, C ^a,b,d  

^a CALIFORNIA PACIFIC MEDICAL CENTER   (United States)

^b UNIVERSITY OF TEXAS HEALTH SCIENCE CENTER AT SAN ANTONIO   (United States)

^c University of Texas Health Science Center   (United States)

^d ALBERT EINSTEIN COLLEGE OF MEDICINE   (United States)

Author keywords

Breast cancer; Innate immune system; Mage b DNA vaccine; Metastases; Old age; Young age

Indexed keywords

DNA VACCINE; GAMMA INTERFERON; GRANULOCYTE MACROPHAGE COLONY STIMULATING FACTOR; INTERLEUKIN 2; LIVE VACCINE; MAGE B ANTIGEN; MAGE B[311-660] ANTIGEN LISTERIOLYSIN O FUSION PROTEIN; PLASMID DNA; PLASMID VECTOR; UNCLASSIFIED DRUG;

ADD ON THERAPY; AGING; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIGEN EXPRESSION; ANTIGEN PRESENTING CELL; ARTICLE; BREAST CARCINOMA; CANCER IMMUNIZATION; CANCER MODEL; CD8+ T LYMPHOCYTE; CELL STIMULATION; CELLULAR IMMUNITY; CONTROLLED STUDY; CYTOKINE RELEASE; DNA VECTOR; DRUG EFFECT; DRUG EFFICACY; FEMALE; FLUORESCENCE ACTIVATED CELL SORTING; GROUPS BY AGE; LISTERIA MONOCYTOGENES; LYMPHATIC DRAINAGE; METASTASIS; METASTASIS INHIBITION; MOUSE; MULTIPLE CYCLE TREATMENT; NONHUMAN; NONVIRAL GENE DELIVERY SYSTEM; PRIORITY JOURNAL;

AGE FACTORS; ANIMALS; CANCER VACCINES; CD8-POSITIVE T-LYMPHOCYTES; FEMALE; MAMMARY NEOPLASMS, ANIMAL; MICE; MICE, INBRED BALB C; NEOPLASM PROTEINS; VACCINATION; VACCINES, DNA;

EID: 70349907077     PISSN: 00070920     EISSN: 15321827     Source Type: Journal    
DOI: 10.1038/sj.bjc.6605329     Document Type: Article

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