High ratio of myeloid dendritic cells to plasmacytoid dendritic cells in blood of patients with acute coronary syndrome

Circulation Journal

Volumn 73, Issue 10, 2009, Pages 1914-1919

  Fukunaga, Takashi ^a   Soejima, Hirofumi ^a   Irie, Atsushi ^a   Fukushima, Ryuichiro ^a   Oe, Yoko ^a   Kawano, Hiroaki ^a   Sumida, Hitoshi ^a   Kaikita, Koichi ^a   Sugiyama, Seigo ^a   Nishimura, Yasuharu ^a   Ogawa, Hisao ^a  

^a KUMAMOTO UNIVERSITY   (Japan)

Author keywords

Acute coronary syndrome; Interferon ; Interleukin 12; Myeloid dendritic cells; Plasmacytoid dendritic cells

Indexed keywords

ALPHA INTERFERON; INTERLEUKIN 12;

ACUTE CORONARY SYNDROME; ADULT; AGED; ARTICLE; CONTROLLED STUDY; DENDRITIC CELL; DISEASE MARKER; FEMALE; HUMAN; MAJOR CLINICAL STUDY; MALE; MYELOID DENDRITIC CELL; PLASMACYTOID DENDRITIC CELL; STABLE ANGINA PECTORIS;

ACUTE CORONARY SYNDROME; AGED; AGED, 80 AND OVER; ANGINA PECTORIS; BIOLOGICAL MARKERS; C-REACTIVE PROTEIN; CASE-CONTROL STUDIES; CELL COUNT; CELL SEPARATION; CORONARY ARTERY DISEASE; DENDRITIC CELLS; DIAGNOSIS, DIFFERENTIAL; FEMALE; FLOW CYTOMETRY; HUMANS; INFLAMMATION MEDIATORS; INTERFERON-ALPHA; INTERLEUKIN-12; LOGISTIC MODELS; MALE; MIDDLE AGED; MYELOID CELLS; ODDS RATIO; PREDICTIVE VALUE OF TESTS; RISK ASSESSMENT; ROC CURVE; RUPTURE;

EID: 70349883813     PISSN: 13469843     EISSN: 13474820     Source Type: Journal    
DOI: 10.1253/circj.CJ-08-1193     Document Type: Article

References (30)

1. Libby P. Inflammation in atherosclerosis. Nature 2002; 420: 868-874.
2. Youssef AA, Chang LT, Hang CL, Wu CJ, Cheng CI, Yang CH, et al. Level and value of interleukin-18 in patients with acute myocardial infarction undergoing primary coronary angioplasty. Circ J 2007; 71: 703-708. (Pubitemid 46683361)
3. Kruk M, Przyłuski J, Kalińczuk Ł, Pregowski J, Deptuch T, Kadziela J, et al; ANIN Myocardial Infarction Registry Group. Association of non-specific inflammatory activation with early mortality in patients with ST-elevation acute coronary syndrome treated with primary angioplasty. Circ J 2008; 72: 205-211.
4. Shah PK. Mechanisms of plaque vulnerability and rapture. J Am Coll Cardiol 2003; 41(Suppl S): 15S-22S.
5. De Palma R, Del Galdo F, Abbate G, Chiariello M, Calabro R, Forte L, et al. Patients with acute coronary syndrome show oligoclonal T-cell recruitment within unstable plaque: Evidence for a local, intracoronary immunologic mechanism. Circulation 2006; 113: 640-646. (Pubitemid 43754327)
6. Frostegard J, Ulfgren AK, Nyberg P, Hedin U, Swedenborg J, Andersson U, et al. Cytokine expression in advanced human atherosclerotic plaques: Dominance of pro-inflammatory (Th1) and macrophage-stimulating cytokines. Atherosclerosis 1999; 145: 33-43. (Pubitemid 29292698)
7. Liuzzo G, Goronzy JJ, Yang H, Kopecky SL, Holmes DR, Frye RL, et al. Monoclonal T-cell proliferation and plaque instability in acute coronary syndromes. Circulation 2000; 101: 2883-2888. (Pubitemid 30415876)
8. Soejima H, Irie A, Miyamoto S, Kajiwara I, Kojima S, Hokamaki J, et al. Preference toward a T-helper type 1 response in patients with coronary spastic angina. Circulation 2003; 107: 2196-2200. (Pubitemid 36547212)
9. Banchereau J, Steinman RM. Dendritic cells and the control of immunity. Nature 1998; 392: 245-252.
10. MacDonald KP, Munster DJ, Clark GJ, Dzionek A, Schmitz J, Hart DN. Characterization of human blood dendritic cell subsets. Blood 2002; 100: 4512-4520. (Pubitemid 35429692)
11. Lord RS, Bobryshev YV. Clustering of dendritic cells in athero-prone areas of the aorta. Atherosclerosis 1999; 146: 197-198.
12. Bobryshev YV, Lord RS. Mapping of vascular dendritic cells in atherosclerotic arteries suggests their involvement in local immune-inflammatory reactions. Cardiovasc Res 1998; 37: 799-810.
13. Yilmaz A, Lochno M, Traeg F, Cicha I, Reiss C, Stumpf C, et al. Emergence of dendritic cells in rupture-prone regions of vulnerable carotid plaques. Atherosclerosis 2004; 176: 101-110. (Pubitemid 39078651)
14. Niessner A, Sato K, Chaikof EL, Colmegna I, Goronzy JJ, Weyand CM. Pathogen-sensing plasmacytoid dendritic cells stimulate cytotoxic T-cell function in the atherosclerotic plaque through interferon-alpha. Circulation 2006; 114: 2482-2489. (Pubitemid 44901521)
15. Bobryshev YV. Dendritic cells in atherosclerosis: Current status of the problem and clinical relevance. Eur Heart J 2005; 26: 1700-1704. (Pubitemid 41219842)
16. Arpinati M, Chirumbolo G, Urbini B, Perrone G, Rondelli D, Anasetti C. Role of plasmacytoid dendritic cells in immunity and tolerance after allogeneic hematopoietic stem cell transplantation. Transpl Immunol 2003; 11: 345-356. (Pubitemid 37120553)
17. Braunwald E. Unstable angina: A classification. Circulation 1989; 80: 410-414.
18. Rifai N, Tracy RP, Ridker PM. Clinical efficacy of an automated high-sensitivity C-reactive protein assay. Clin Chem 1999; 45: 2136-2141.
19. Dzionek A, Fuchs A, Schmidt P, Cremer S, Zysk M, Miltenyi S, et al. BDCA-2, BDCA-3, and BDCA-4: Three markers for distinct subsets of dendritic cells in human peripheral blood. J Immunol 2000; 165: 6037-6046.
20. Van Vre EA, Hoymans VY, Bult H, Lenjou M, Van Bockstaele DR, Vrints CJ, et al. Decreased number of circulating plasmacytoid dendritic cells in patients with atherosclerotic coronary artery disease. Coron Artery Dis 2006; 17: 243-248. (Pubitemid 44324834)
21. Weis M, Schlichting CL, Engleman EG, Cooke JP. Endothelial determinants of dendritic cell adhesion and migration: New implications for vascular diseases. Arterioscler Thromb Vasc Biol 2002; 22: 1817-1823. (Pubitemid 35315767)
22. Alderman CJ, Bunyard PR, Chain BM, Foreman JC, Leake DS, Katz DR. Effects of oxidised low density lipoprotein on dendritic cells: A possible immunoregulatory component of the atherogenic micro-environment? Cardiovasc Res 2002; 55: 806-819.
23. Coutant F, Agaugue S, Perrin-Cocon L, Andre P, Lotteau V. Sensing environmental lipids by dendritic cell modulates its function. J Immunol 2004; 172: 54-60. (Pubitemid 38020455)
24. Niessner A, Shin MS, Pryshchep O, Goronzy JJ, Chaikof EL, Weyand CM. Synergistic proinflammatory effects of the antiviral cytokine interferon-alpha and Toll-like receptor 4 ligands in the atherosclerotic plaque. Circulation 2007; 116: 2043-2052. (Pubitemid 350023750)
25. Banchereau J, Briere F, Caux C, Davoust J, Lebecque S, Liu YJ, et al. Immunobiology of dendritic cells. Annu Rev Immunol 2000; 18: 767-811.
26. Albert MA, Danielson E, Rifai N, Ridker PM; PRINCE Investigators. Effect of statin therapy on C-reactive protein levels: The pravastatin inflammation/CRP evaluation (PRINCE): A randomized trial and cohort study. JAMA 2001; 286: 64-70. (Pubitemid 32606333)
27. Ridker PM; JUPITER Study Group. Rosuvastatin in the primary prevention of cardiovascular disease among patients with low levels of low-density lipoprotein cholesterol and elevated high-sensitivity C-reactive protein: Rationale and design of the JUPITER trial. Circulation 2003; 108: 2292-2297.
28. Ridker PM, Fonseca FA, Genest J, Gotto AM, Kastelein JJ, Khurmi NS, et al; JUPITER Trial Study Group. Baseline characteristics of participants in the JUPITER trial, a randomized placebo-controlled primary prevention trial of statin therapy among individuals with low low-density lipoprotein cholesterol and elevated high-sensitivity C-reactive protein. Am J Cardiol 2007; 100: 1659-1664. (Pubitemid 350122337)
29. Van Vré EA, Bult H, Hoymans VY, Van Tendeloo VF, Vrints CJ, Bosmans JM. Human C-reactive protein activates monocyte-derived dendritic cells and induces dendritic cell-mediated T-cell activation. Arterioscler Thromb Vasc Biol 2008; 28: 511-518.
30. Shi H, Ge J, Fang W, Yao K, Sun A, Huang R, et al. Peripheral-blood dendritic cells in men with coronary heart disease. Am J Cardiol 2007; 100: 593-597. (Pubitemid 47223132)