Long-acting inhaled anticholinergic therapy improves sleeping oxygen saturation in COPD

European Respiratory Journal

Volumn 23, Issue 6, 2004, Pages 825-831

  McNicholas, Walter T ^a   Calverley, P M A ^b   Lee, A ^c   Edwards, J C ^d   Williams, A ^e   Rees, J ^e   Cayton, R ^f   Chakravorty, I ^f   van Noord, J A ^g   Stradling, J R ^h   Hanning, C ⁱ   Morgan, M ⁱ   Patel, K ^j   Shneerson, J E ^k   Kilfeather, S A ^l   Catterall, J R ^m   Elliott, M ⁿ  

^a ST VINCENT S UNIVERSITY HOSPITAL   (Ireland)

^b UNIVERSITY HOSPITAL AINTREE   (United Kingdom)

^c BOEHRINGER INGELHEIM LTD   (United Kingdom)

^d Boehringer Ingelheim Ireland Ltd   (Ireland)

^e ST THOMAS HOSPITAL   (United Kingdom)

^f BIRMINGHAM HEARTLANDS HOSPITAL   (United Kingdom)

^g Sittard Geleen Heerlen   (Netherlands)

^h CHURCHILL HOSPITAL   (United Kingdom)

ⁱ LEICESTER GENERAL HOSPITAL   (United Kingdom)

^j WESTERN INFIRMARY   (United Kingdom)

^k PAPWORTH HOSPITAL   (United Kingdom)

^l Business and Innovation Centre   (United Kingdom)

^m BRISTOL ROYAL INFIRMARY   (United Kingdom)

ⁿ ST JAMES S UNIVERSITY HOSPITAL   (United Kingdom)

more..

Author keywords

Chronic obstructive pulmonary disease; Randomised cotrolled trial; Sleep disordered breathing; Tiotropium bromide

Indexed keywords

CHOLINERGIC RECEPTOR BLOCKING AGENT; OXYGEN; PLACEBO; TIOTROPIUM BROMIDE;

ADULT; AGED; ARTERIAL OXYGEN SATURATION; ARTERIAL OXYGEN TENSION; ARTICLE; CHOLINERGIC RECEPTOR BLOCKING; CHRONIC OBSTRUCTIVE LUNG DISEASE; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; CORRELATION ANALYSIS; DISEASE SEVERITY; DOUBLE BLIND PROCEDURE; DRY POWDER; FEMALE; FORCED EXPIRATORY VOLUME; HUMAN; HYPOVENTILATION; INHALER; LUNG PERFUSION; LUNG VENTILATION; MAJOR CLINICAL STUDY; MALE; MULTICENTER STUDY; OXYGEN SATURATION; POLYSOMNOGRAPHY; PREDICTION; PRIORITY JOURNAL; RANDOMIZED CONTROLLED TRIAL; REM SLEEP; REST; SLEEP; SLEEP TIME; TREATMENT OUTCOME; WAKEFULNESS;

EID: 3042549235     PISSN: 09031936     EISSN: None     Source Type: Journal    
DOI: 10.1183/09031936.04.00085804     Document Type: Article

References (34)

1. McNicholas WT. Impact of sleep in COPD. Chest 2000; 117, Suppl. 2: 48-53s.
2. Tirlapur VG, Mir MA. Nocturnal hypoxemia and associated electrocardiographic changes in patients with chronic obstructive airways disease. N Engl J Med 1982; 306: 125-30.
3. McNicholas WT, Fitzgerald MX. Nocturnal deaths among patients with chronic bronchitis and emphysema. BMJ 1984; 289: 878.
4. Caterall JR, Calverley PMA, McNee W, et al. Mechanism of transient nocturnal hypoxemia in hypoxic chronic bronchitis and emphysema. J Appl Physiol 1985; 59: 1698-1703.
5. Johnson MW, Remmers JE. Accessory muscle activity during sleep in chronic obstructive pulmonary disease. J Appl Physiol 1984; 57: 1011-1017.
6. Baust W, Bohernt B. The regulation of heart rate during sleep. Exp Brain Res 1969; 7: 169-180.
7. Goldstein RS, Ramcharan V, Bowes G, McNicholas WT, Bradley D, Phillipson EA. Effect of supplemental nocturnal oxygen on gas exchange in patients with severe obstructive lung disease. New Engl J Med 1984; 310: 425-429.
8. Calverley PM, Brezinova V, Douglas NJ, Catterall JR, Flenley DC. The effect of oxygenation on sleep quality in chronic bronchitis and emphysema. Am Rev Respir Dis 1982; 126: 206-210.
9. Fleetham J, West P, Mezon B, Conway W, Roth T, Kryger M. Sleep, arousals, and oxygen desaturation in chronic obstructive pulmonary disease. The effect of oxygen therapy. Am Rev Respir Dis 1982; 126: 429-433.
10. Cormick W, Olson LG, Hensley MJ, Saunders NA. Nocturnal hypoxaemia and quality of sleep in patients with chronic obstructive lung disease. Thorax 1986; 41: 846-854.
11. Martin RJ, Bucher Bartelson BL, Smith P, et al. Effect of ipratropium bromide treatment on oxygen saturation and sleep quality in COPD. Chest 1999; 115: 1525-1532.
12. Maesen FP, Smeets JJ, Sledsens TJ, Wald FD, Cornelissen PJ. Tiotropium bromide, a new long-acting antimuscarinic bronchodilator: a pharmacodynamic study in patients with chronic obstructive pulmonary disease (COPD). Dutch Study Group. Eur Respir J 1995; 8: 1506-1513.
13. Littner MR, Ilowite JS, Tashkin DP, et al. Long-acting bronchodilation with once-daily dosing of tiotropium (Spiriva) in stable chronic obstructive pulmonary disease. Am J Respir Crit Care Med 2000; 161: 1136-1142.
14. Casaburi R, Mahler DA, Jones PW, et al. A long-term evaluation of once-daily inhaled tiotropium in chronic obstructive pulmonary disease. Eur Respir J 2002; 19: 217-224.
15. American Thoracic Society. Standards for the diagnosis and care of patients with chronic obstructive pulmonary disease (COPD) and asthma. Am Rev Respir Dis 1987; 136: 225-244.
16. Quanjer PhH, Tammeling GJ, Cotes JE, Pedersen OF, Peslin R, Yernault J-C. Lung volumes and forced ventilatory flows. Report working party standardisation of lung function tests European Community for Steel and Coal. Eur Respir J 1993; 6: Suppl. 16, 5-40.
17. American Thoracic Society. Indications and standards for cardiopulmonary sleep studies. Am Rev Respir Dis 1989; 139: 559-568.
18. Rechtschaffen A, Kales A. A Manual of Standardized Terminology, Techniques and Scoring System for Sleep Stages of Human Subjects. Washington, US Government Printing Office, Public Health Service, 1968.
19. Johns MW. A new method for measuring daytime sleepiness: The Epworth sleepiness scale. Sleep 1991; 14: 540-545.
20. Johns MW. Daytime sleepiness, scoring and obstructive sleep apnoea. The Epworth sleepiness scale. Chest 1993; 103: 30-36.
21. Fleiss JL. The design analysis of clinical experiments. In: Analysis of Covariance and the Study of Change. New York, USA, John Wiley and Sons, 1986: pp. 186-219.
22. Senn S. Baseline and covariate information. In: Statistical Issues in Drug Development. Chichester, UK, John Wiley and Sons, 1997: pp. 95-109.
23. Mulloy E, McNicholas WT. Theophylline improves gas exchange during rest, exercise and sleep in severe chronic obstructive pulmonary disease. Am Rev Respir Dis 1993; 148: 1030-1036.
24. Douglas NJ, Calverley PMA, Leggett RJE, Brash HM, Flenley DC, Brezinova V. Transient hypoxaemia during sleep in chronic bronchitis and emphysema. Lancet 1979; 1: 1-4.
25. Fletcher EC, Levin DC. Cardiopulmonary hemodynamics during sleep in subjects with chronic obstructive pulmonary disease. The effect of short- and long-term oxygen. Chest 1984; 85: 6-14.
26. Chrystyn H, Mulley BA, Peake MD. Dose response relation to oral theophylline in severe chronic obstructive airway disease. BMJ 1988; 297: 1506-1510.
27. Celli B, ZuWallack R, Wang S, Kesten S. Improvement in resting inspiratory capacity and hyperinflation with tiotropium in COPD patients with increased static lung volumes. Chest 2003; 124: 1743-1748.
28. Fletcher EC, Luckett RA, Miller T, et al. Pulmonary vascular hemodynamics in chronic lung disease patients with and without oxyhemoglobin desaturation during sleep. Chest 1989; 95: 757-766.
29. Collard P, Dury M, Delguste P, Aubert G, Rodenstein DO. Movement arousals and sleep-related disordered breathing in adults. Am J Respir Crit Care Med 1996; 154: 454-459.
30. Rennard SI, Decramer M, Calverley PMA, et al. The impact of COPD in North America and Europe: the patient's perspective of the Confronting COPD International survey. Eur Respir J 2002; 20: 1-7.
31. Tashkin D, Kesten S. Long-term treatment benefits with tiotropium in COPD patients with and without short-term bronchodilator responses. Chest. 2003; 123: 1441-1449.
32. Jones PW, Bosh TK. Quality of life changes in COPD patients treated with salmeterol. Am J Respir Crit Care Med 1997; 155: 1283-1289.
33. Leusch A, Eichorn B, Müller G, Rominger K-L. Pharmacokinetics and tissue distribution of the anticholinergics tiotropium and ipratropium in the rat and dog. Biopharm. Drug Dispos 2001; 22: 199-212.
34. Calverley PMA, Lee A, Towse LJ, Witek TJ, Kesten S. Effect of tiotropium bromide on circadian variation in airflow limitation in chronic obstructive pulmonary disease. Thorax 2003; 58: 855-860.