StaR Child Health: an initiative for RCTs in children

The Lancet

Volumn 374, Issue 9698, 2009, Pages 1310-1312

  Klassen, Terry P ^a   Hartling, Lisa ^a   Hamm, Michele ^a   van der Lee, Johanna H ^b   Ursum, Jennie ^b   Offringa, Martin ^b  

^a STOLLERY CHILDREN S HOSPITAL   (Canada)

^b ACADEMIC MEDICAL CENTER   (Netherlands)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIHYPERTENSIVE AGENT; PLACEBO;

ANTIHYPERTENSIVE THERAPY; ARTICLE; BLOOD PRESSURE MEASUREMENT; CHILD HEALTH; CLINICAL RESEARCH; DATA BASE; DOSE CALCULATION; DRUG EFFICACY; DRUG RESEARCH; DRUG SAFETY; EPILEPSY; HUMAN; HYPERTENSION; MEDICAL DECISION MAKING; MEDICAL LITERATURE; MEDICAL RESEARCH; MIGRAINE; OFF LABEL DRUG USE; PRACTICE GUIDELINE; PRIORITY JOURNAL; PROFESSIONAL KNOWLEDGE; RANDOMIZED CONTROLLED TRIAL; SAMPLE SIZE; TREATMENT OUTCOME; TREATMENT RESPONSE; UNCERTAINTY;

AGE FACTORS; CHILD; HUMANS; RANDOMIZED CONTROLLED TRIALS AS TOPIC;

EID: 70349873196     PISSN: 01406736     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0140-6736(09)61803-1     Document Type: Note

References (15)

1. StaR Child Health. Standards for research in child health (April 24, 2009). http://www.starchildhealth.org (accessed Sept 18, 2009).
2. Thomson D., Tjosvold L., Vandermeer B., Klassen T.P., and Hartling L. Paediatric RCTs and CCTs: an analysis of trends over time from 1948 to 2006. Zeitschrift fur Evidenz, Fortbildung und Qualitat im Gesundheitswesen 102 suppl VI (2008) 80 (abstr).
3. Hartling L., Ospina M., Liang Y., Dryden D.M., and Klassen T.P. Risk of bias versus quality assessment in systematic reviews of randomized controlled trials. BMJ 339 (2009) b4006
4. Cramer K., Wiebe N., Moyer V., et al. Children in reviews: methodological issues in child-relevant evidence synthesis. BMC Pediatr 5 (2005) 38
5. Cohen E., Uleryk E., Jasuja M., and Parkin P.C. An absence of pediatric randomized controlled trials in general medical journals, 1985-2004. J Clin Epidemiol 60 (2007) 118-123
6. Bosch X. Europe follows U.S. in testing drugs for children. Science 309 (2005) 1799
7. Smyth R.L. Making a difference: the clinical research programme for children. Arch Dis Child 92 (2007) 835-837
8. Weber E.H., Timmermans I.T., and Offringa M. The Dutch medicines research network: a new resource for clinical trials. Pediatr Drugs 11 (2009) 161-163
9. Klassen T.P., Hartling L., Craig J.C., and Offringa M. Children are not just small adults: the urgent need for high-quality trial evidence in children. PLoS Med 5 (2008) e172
10. Frakking F.N.J., van der Lee J.H., Klassen T.P., Offringa M., and for the StaR-Child Health Group. Survey of current guidance for child health clinical trials: the StaR Child Health project: standards for research with children (May 1, 2009). http://www.who.int/childmedicines/publications/GUIDANCECHILDHEALTH.pdf (accessed Sept 18, 2009).
11. Gimpel C., Wuhl E., Arbeiter K., et al., for the ESCAPE Trial Group. Superior consistency of ambulatory blood pressure monitoring in children: implications for clinical trials. J Hypertens 27 (2009) 1568-1574
12. Rheims S., Cucherat M., Arzimanoglou A., and Ryvlin P. Greater response to placebo in children than in adults: a systematic review and meta-analysis in drug-resistant partial epilepsy. PLoS Med 5 (2008) e166
13. Fernandes R., Ferreira J.J., and Sampaio C. The placebo response in studies in acute migraine. J Pediatr 152 (2008) 527-533
14. van der Lee J.H., Wesseling J., Tanck M.W., and Offringa M. Efficient ways exist to obtain the optimal sample size in clinical trials in rare diseases. J Clin Epidemiol 61 (2008) 324-330
15. Sinha I., Jones L., Smyth R.L., and Williamson P.R. A systematic review of studies that aim to determine which outcomes to measure in clinical trials in children. PLoS Med 5 (2008) e96