-
1
-
-
21244474773
-
Beyond 5-fluorouracil: New horizons in systemic therapy for advanced colorectal cancer
-
Khamly K, Jefford M, Michael M, Zalcberg J. Beyond 5-fluorouracil: New horizons in systemic therapy for advanced colorectal cancer. Expert Opin Investig Drugs 2005;14:607-628
-
(2005)
Expert Opin Investig Drugs
, vol.14
, pp. 607-628
-
-
Khamly, K.1
Jefford, M.2
Michael, M.3
Zalcberg, J.4
-
2
-
-
20644432867
-
Bevacizumab in combination with fluorouracil and leucovorin: An active regimen for first-line metastatic colorectal cancer
-
Hurwitz HI, Fehrenbacher L, Hainsworth JD, Heim W, Berlin J, Holmgren E, et al. Bevacizumab in combination with fluorouracil and leucovorin: An active regimen for first-line metastatic colorectal cancer. J Clin Oncol 2005;23:3502-3508
-
(2005)
J Clin Oncol
, vol.23
, pp. 3502-3508
-
-
Hurwitz, H.I.1
Fehrenbacher, L.2
Hainsworth, J.D.3
Heim, W.4
Berlin, J.5
Holmgren, E.6
-
3
-
-
34047172438
-
Colorectal cancer: A multipathway disease
-
Jass J.R. Colorectal cancer: A multipathway disease. Crit Rev Oncogenesis 2006;12:273-287
-
(2006)
Crit Rev Oncogenesis
, vol.12
, pp. 273-287
-
-
Jass, J.R.1
-
4
-
-
0031004175
-
Genetic instability in colorectal cancers
-
Lengauer C, Kinzler K W, Vogelstein B. Genetic instability in colorectal cancers. Nature 1997;386:623-627
-
(1997)
Nature
, vol.386
, pp. 623-627
-
-
Lengauer, C.1
Kinzler, K.W.2
Vogelstein, B.3
-
5
-
-
0032534069
-
A National Cancer Institute Workshop on Microsatellite Instability for cancer detection and familial predisposition: Development of international criteria for the determination of microsatellite instability in colorectal cancer
-
Boland CR, Thibodeau SN, Hamilton SR, Sidransky D, Eshleman JR, Burt RW, et al. A National Cancer Institute Workshop on Microsatellite Instability for cancer detection and familial predisposition: Development of international criteria for the determination of microsatellite instability in colorectal cancer. Cancer Res 1998;58: 5248-5257
-
(1998)
Cancer Res
, vol.58
, pp. 5248-5257
-
-
Boland, C.R.1
Thibodeau, S.N.2
Hamilton, S.R.3
Sidransky, D.4
Eshleman, J.R.5
Burt, R.W.6
-
6
-
-
0030592517
-
Lessons from hereditary colorectal cancer
-
Kinzler K W, Vogelstein B. Lessons from hereditary colorectal cancer. Cell 1996;87:159-170
-
(1996)
Cell
, vol.87
, pp. 159-170
-
-
Kinzler, K.W.1
Vogelstein, B.2
-
7
-
-
0023748414
-
Genetic alterations during colorectal-tumor development
-
Vogelstein B, Fearon ER, Hamilton SR, Kern SE, Preisinger AC, Leppert M, et al. Genetic alterations during colorectal-tumor development. N Engl J Med 1988;319:525-532
-
(1988)
N Engl J Med
, vol.319
, pp. 525-532
-
-
Vogelstein, B.1
Fearon, E.R.2
Hamilton, S.R.3
Kern, S.E.4
Preisinger, A.C.5
Leppert, M.6
-
8
-
-
70349795803
-
Molecular gate keepers succumb to gene aberrations in colorectal cancer in Kashmiri population, revealing a high incidence area
-
Sameer AS, Pandith AS, Syeed N, Chowdhri NA, Alam KA, Siddiqi MA. Molecular gate keepers succumb to gene aberrations in colorectal cancer in Kashmiri population, revealing a high incidence area. Saudi J Gastroenterol 2009;15:244-252
-
(2009)
Saudi J Gastroenterol
, vol.15
, pp. 244-252
-
-
Sameer, A.S.1
Pandith, A.S.2
Syeed, N.3
Chowdhri, N.A.4
Alam, K.A.5
Siddiqi, M.A.6
-
9
-
-
0036258111
-
The IARC TP53 database: New online mutation analysis and recommendations to users
-
Olivier M, Eeles R, Hollstein M, Khan MA, Harris CC, Hainaut P. The IARC TP53 database: New online mutation analysis and recommendations to users. Hum Mutat 2002;19:607-614
-
(2002)
Hum Mutat
, vol.19
, pp. 607-614
-
-
Olivier, M.1
Eeles, R.2
Hollstein, M.3
Khan, M.A.4
Harris, C.C.5
Hainaut, P.6
-
10
-
-
44449124376
-
Clinicopathological analysis of colorectal cancers with PIK3CA mutations in Middle Eastern population
-
DOI 10.1038/sj.onc.1211013, PII 1211013
-
Abubaker J, Bavi P, Al-Harbi S, Ibrahim M, Siraj AK, Al-Sanea N, et al. Clinicopathological analysis of colorectal cancers with PIK3CA mutations in Middle Eastern population. Oncogene 2008;27:3539-3545 (Pubitemid 351793794)
-
(2008)
Oncogene
, vol.27
, Issue.25
, pp. 3539-3545
-
-
Abubaker, J.1
Bavi, P.2
Al-Harbi, S.3
Ibrahim, M.4
Siraj, A.K.5
Al-Sanea, N.6
Abduljabbar, A.7
Ashari, L.H.8
Alhomoud, S.9
Al-Dayel, F.10
Uddin, S.11
Al-Kuraya, K.S.12
-
11
-
-
4944235005
-
Systematic review of genetic influences on the prognosis of colorectal cancer
-
Anwar S, Frayling IM, Scott NA, Carlson GL. Systematic review of genetic influences on the prognosis of colorectal cancer. Br J Surg 2004;91:1275-1291
-
(2004)
Br J Surg
, vol.91
, pp. 1275-1291
-
-
Anwar, S.1
Frayling, I.M.2
Scott, N.A.3
Carlson, G.L.4
-
12
-
-
20444491228
-
Bamezai RN. p53 mutation profile of squamous cell carcinomas of the esophagus in Kashmir (India): A high-incidence area
-
Mir MM, Dar NA, Gochhait S, Zargar SA, Ahangar AG, Bamezai RN. p53 mutation profile of squamous cell carcinomas of the esophagus in Kashmir (India): A high-incidence area. Int J Cancer 2005;116:62-68
-
(2005)
Int J Cancer
, vol.116
, pp. 62-68
-
-
Mir, M.M.1
Dar, N.A.2
Gochhait, S.3
Zargar, S.A.4
Ahangar, A.G.5
-
13
-
-
0037805547
-
RAS oncogenes: The first 30 years
-
Malumbres M, Barbacid M. RAS oncogenes: The first 30 years. Nat Rev 2003;3:459-465
-
(2003)
Nat Rev
, vol.3
, pp. 459-465
-
-
Malumbres, M.1
Barbacid, M.2
-
14
-
-
33646228635
-
KRAS mutation status is predictive of response to cetuximab therapy in colorectal cancer
-
Lievre A, Bachet JB, Le Corre D, Boige V, Landi B, Emile JF, et al. KRAS mutation status is predictive of response to cetuximab therapy in colorectal cancer. Cancer Res 2006;66:3992-3995
-
(2006)
Cancer Res
, vol.66
, pp. 3992-3995
-
-
Lievre, A.1
Bachet, J.B.2
Le Corre, D.3
Boige, V.4
Landi, B.5
Emile, J.F.6
-
15
-
-
62449302407
-
PIK3CA mutations in colorectal cancer are associated with clinical resistance to EGFR-targeted monoclonal antibodies
-
Sartore-Bianchi A, Martini M, Molinari F, Veronese S, Nichelatti M, Artale S, et al. PIK3CA mutations in colorectal cancer are associated with clinical resistance to EGFR-targeted monoclonal antibodies. Cancer Res 2009;69:1851-1857
-
(2009)
Cancer Res
, vol.69
, pp. 1851-1857
-
-
Sartore-Bianchi, A.1
Martini, M.2
Molinari, F.3
Veronese, S.4
Nichelatti, M.5
Artale, S.6
-
16
-
-
0035908493
-
Blocking oncogenic Ras signaling for cancer therapy
-
Adjei AA. Blocking oncogenic Ras signaling for cancer therapy. J Natl Cancer Inst 2001;93:1062-1074
-
(2001)
J Natl Cancer Inst
, vol.93
, pp. 1062-1074
-
-
Adjei, A.A.1
-
17
-
-
0024376173
-
Ras oncogenes in human cancer: A review
-
Bos JL. Ras oncogenes in human cancer: A review. Cancer Res 1989;49:4682-4689
-
(1989)
Cancer Res
, vol.49
, pp. 4682-4689
-
-
Bos, J.L.1
-
18
-
-
0025312728
-
A genetic model for colorectal tumorigenesis
-
Fearon ER, Vogelstein B. A genetic model for colorectal tumorigenesis. Cell 1990;61:759-767
-
(1990)
Cell
, vol.61
, pp. 759-767
-
-
Fearon, E.R.1
Vogelstein, B.2
-
19
-
-
0038731306
-
K-ras oncogene mutations in sporadic colorectal cancer in the Netherlands Cohort Study
-
Brink M, de Goeij A F, Weijenberg M P, Roemen GM, Lentjes MH, Pachen MM, et al. K-ras oncogene mutations in sporadic colorectal cancer in The Netherlands Cohort Study. Carcinogenesis 2003;24:703-710
-
(2003)
Carcinogenesis
, vol.24
, pp. 703-710
-
-
Brink, M.1
De Goeij, A.F.2
Weijenberg, M.P.3
Roemen, G.M.4
Lentjes, M.H.5
Pachen, M.M.6
-
20
-
-
0023256456
-
Prevalence of ras gene mutations in human colorectal cancers
-
Bos JL, Fearon ER, Hamilton SR, Verlaan-de Vries M, van Boom JH, van der Eb AJ, et al. Prevalence of ras gene mutations in human colorectal cancers. Nature 1987;327:293-297
-
(1987)
Nature
, vol.327
, pp. 293-297
-
-
Bos, J.L.1
Fearon, E.R.2
Hamilton, S.R.3
Verlaan-De Vries, M.4
Van Boom, J.H.5
Van Der Eb, A.J.6
-
21
-
-
0020624456
-
Activation of Ki-ras2 gene in human colon and lung carcinomas by two different point mutations
-
Capon DJ, Seeburg PH, McGrath J P, Hayflick JS, Edman U, Levinson AD, et al. Activation of Ki-ras2 gene in human colon and lung carcinomas by two different point mutations. Nature 1983;304:507-513
-
(1983)
Nature
, vol.304
, pp. 507-513
-
-
Capon, D.J.1
Seeburg, P.H.2
McGrath, J.P.3
Hayflick, J.S.4
Edman, U.5
Levinson, A.D.6
-
22
-
-
0032883992
-
A relationship between K-ras gene mutations and some clinical and histologic variables in patients with primary colorectal carcinoma
-
Beranek M, Bures J, Palicka V, Jandik P, Langr F, Nejedla E. A relationship between K-ras gene mutations and some clinical and histologic variables in patients with primary colorectal carcinoma. Clin Chem Lab Med 1999;37:723-727
-
(1999)
Clin Chem Lab Med
, vol.37
, pp. 723-727
-
-
Beranek, M.1
Bures, J.2
Palicka, V.3
Jandik, P.4
Langr, F.5
Nejedla, E.6
-
23
-
-
0027212026
-
Prevalence of G-to-T transversions among K-ras oncogene mutations in human colorectal tumors in Yugoslavia
-
Urosevic N, Krtolica K, Skaro-Milic A, Knezevic-Usaj S, Dujic A. Prevalence of G-to-T transversions among K-ras oncogene mutations in human colorectal tumors in Yugoslavia. Int J Cancer 1993;54:249-254
-
(1993)
Int J Cancer
, vol.54
, pp. 249-254
-
-
Urosevic, N.1
Krtolica, K.2
Skaro-Milic, A.3
Knezevic-Usaj, S.4
Dujic, A.5
-
24
-
-
17944391595
-
Frequency and clinicopathology associations of K-ras mutations in colorectal cancer in a northeast Mexican population
-
Martinez-Garza SG, Nunez-Salazar A, Calderon-Garciduenas AL, Bosques-Padilla FJ, Niderhauser-Garcia A, Barrera-Saldana HA. Frequency and clinicopathology associations of K-ras mutations in colorectal cancer in a northeast Mexican population. Dig Dis 1999;17:225-229
-
(1999)
Dig Dis
, vol.17
, pp. 225-229
-
-
Martinez-Garza, S.G.1
Nunez-Salazar, A.2
Calderon-Garciduenas, A.L.3
Bosques-Padilla, F.J.4
Niderhauser-Garcia, A.5
Barrera-Saldana, H.A.6
-
25
-
-
42149083899
-
Mutations in the RAS-MAPK, PI(3)K (phosphatidylinositol-3-OH kinase) signaling network correlate with poor survival in a population-based series of colon cancers
-
Barault L, Veyrie N, Jooste V, Lecorre D, Chapusot C, Ferraz JM, et al. Mutations in the RAS-MAPK, PI(3)K (phosphatidylinositol-3-OH kinase) signaling network correlate with poor survival in a population-based series of colon cancers. Int J Cancer 2008;122:2255-2259
-
(2008)
Int J Cancer
, vol.122
, pp. 2255-2259
-
-
Barault, L.1
Veyrie, N.2
Jooste, V.3
Lecorre, D.4
Chapusot, C.5
Ferraz, J.M.6
-
26
-
-
16544367948
-
K-ras codon 12 and 13 mutations are correlated with differential patterns of tumor cell dissemination in colorectal cancer patients
-
Conzelmann M, Linnemann U, Berger MR. K-ras codon 12 and 13 mutations are correlated with differential patterns of tumor cell dissemination in colorectal cancer patients. Int J Oncol 2004;24: 1537-1544
-
(2004)
Int J Oncol
, vol.24
, pp. 1537-1544
-
-
Conzelmann, M.1
Linnemann, U.2
Berger, M.R.3
-
28
-
-
0029919079
-
High frequency of p53 gene mutations in primary breast cancers in Japanese women: A low-incidence population
-
Hartmann A, Blaszyk H, Saitoh S, Tsushima K, Tamura Y, Cunningham JM, et al. High frequency of p53 gene mutations in primary breast cancers in Japanese women: A low-incidence population. Br J Cancer 1996;73:896-901.
-
(1996)
Br J Cancer
, vol.73
, pp. 896-901
-
-
Hartmann, A.1
Blaszyk, H.2
Saitoh, S.3
Tsushima, K.4
Tamura, Y.5
Cunningham, J.M.6
-
29
-
-
34447339121
-
HER2, TOP2A, CCND1, EGFR and C-MYC oncogene amplification in colorectal cancer
-
Al-Kuraya K, Novotny H, Bavi P, Siraj AK, Uddin S, Ezzat A, et al. HER2, TOP2A, CCND1, EGFR and C-MYC oncogene amplification in colorectal cancer. J Clin Pathol 2007;60:768-772
-
(2007)
J Clin Pathol
, vol.60
, pp. 768-772
-
-
Al-Kuraya, K.1
Novotny, H.2
Bavi, P.3
Siraj, A.K.4
Uddin, S.5
Ezzat, A.6
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