메뉴 건너뛰기




Volumn 48, Issue 9, 2009, Pages 1065-1068

Clinical expression of leflunomide-induced pneumonitis

Author keywords

Delayed hypersensitivity; Hypersensitivity pneumonitis; Interstitial lung disease; Leflunomide induced pneumonitis

Indexed keywords

ANTIBIOTIC AGENT; COLESTYRAMINE; LEFLUNOMIDE; METHOTREXATE; STEROID; ANTIRHEUMATIC AGENT; IMMUNOSUPPRESSIVE AGENT; ISOXAZOLE DERIVATIVE;

EID: 70349783402     PISSN: 14620324     EISSN: 14620332     Source Type: Journal    
DOI: 10.1093/rheumatology/kep050     Document Type: Article
Times cited : (76)

References (38)
  • 1
    • 0033565880 scopus 로고    scopus 로고
    • In vivo activity of leflunomide: pharmacokinetic analyses and mechanism of immunosuppression
    • Chong AS, Huang W, Liu W et al. In vivo activity of leflunomide: pharmacokinetic analyses and mechanism of immunosuppression. Transplantation 1999;68:100-9.
    • (1999) Transplantation , vol.68 , pp. 100-109
    • Chong, A.S.1    Huang, W.2    Liu, W.3
  • 2
    • 18044400396 scopus 로고    scopus 로고
    • Two-year, blinded, randomized, controlled trial of treatment of active rheumatoid arthritis with leflunomide compared with methotrexate. Utilization of Leflunomide in the Treatment of Rheumatoid Arthritis Trial Investigator Group
    • Cohen S, Cannon GW, Schiff M et al. Two-year, blinded, randomized, controlled trial of treatment of active rheumatoid arthritis with leflunomide compared with methotrexate. Utilization of Leflunomide in the Treatment of Rheumatoid Arthritis Trial Investigator Group. Arthritis Rheum 2001;44:1984-92.
    • (2001) Arthritis Rheum , vol.44 , pp. 1984-1992
    • Cohen, S.1    Cannon, G.W.2    Schiff, M.3
  • 3
    • 6744262231 scopus 로고    scopus 로고
    • A comparison of the efficacy and safety of leflunomide and methotrexate for the treatment of rheumatoid arthritis
    • Emery P, Breedveld FC, Lemmel EM et al. A comparison of the efficacy and safety of leflunomide and methotrexate for the treatment of rheumatoid arthritis. Rheumatology 2000;39:655-65.
    • (2000) Rheumatology , vol.39 , pp. 655-665
    • Emery, P.1    Breedveld, F.C.2    Lemmel, E.M.3
  • 4
    • 33645219514 scopus 로고    scopus 로고
    • Leflunomide improves psoriasis in patients with psoriatic arthritis: an in-depth analysis of data from the TOPAS study
    • Nash P, Thaci D, Behrens F, Falk F, Kaltwasser JP. Leflunomide improves psoriasis in patients with psoriatic arthritis: an in-depth analysis of data from the TOPAS study. Dermatology 2006;212:238-49.
    • (2006) Dermatology , vol.212 , pp. 238-249
    • Nash, P.1    Thaci, D.2    Behrens, F.3    Falk, F.4    Kaltwasser, J.P.5
  • 5
    • 39149095619 scopus 로고    scopus 로고
    • Leflunomide as adjuvant treatment of dermatomyositis
    • Boswell JS, Costner MI. Leflunomide as adjuvant treatment of dermatomyositis. J Am Acad Dermatol 2008;58:403-6.
    • (2008) J Am Acad Dermatol , vol.58 , pp. 403-406
    • Boswell, J.S.1    Costner, M.I.2
  • 6
    • 20244384845 scopus 로고    scopus 로고
    • Leflunomide or methotrexate for juvenile rheumatoid arthritis
    • Silverman E, Mouy R, Spiegel L et al. Leflunomide or methotrexate for juvenile rheumatoid arthritis. N Engl J Med 2005;352:1655-66.
    • (2005) N Engl J Med , vol.352 , pp. 1655-1666
    • Silverman, E.1    Mouy, R.2    Spiegel, L.3
  • 8
    • 40749145348 scopus 로고    scopus 로고
    • Treatment of Crohn's disease with leflunomide as second-line immunosuppression: a phase 1 open-label trial on efficacy, tolerability and safety
    • Holtmann MH, Gerts AL, Weinman A, Galle PR, Neurath MF. Treatment of Crohn's disease with leflunomide as second-line immunosuppression: a phase 1 open-label trial on efficacy, tolerability and safety. Dig Dis Sci 2008;53:1025-32.
    • (2008) Dig Dis Sci , vol.53 , pp. 1025-1032
    • Holtmann, M.H.1    Gerts, A.L.2    Weinman, A.3    Galle, P.R.4    Neurath, M.F.5
  • 10
    • 1542377415 scopus 로고    scopus 로고
    • Japan deaths spark concerns over arthritis drug
    • McCurry J. Japan deaths spark concerns over arthritis drug. Lancet 2004;363:461.
    • (2004) Lancet , vol.363 , pp. 461
    • McCurry, J.1
  • 11
    • 45849124232 scopus 로고    scopus 로고
    • BSR/BHPR guideline for diseasemodifying anti-rheumatic drug (DMARD) therapy in consultation with the British Association of Dermatologists
    • Chakravarty K, McDonald H, Pullar T et al. BSR/BHPR guideline for diseasemodifying anti-rheumatic drug (DMARD) therapy in consultation with the British Association of Dermatologists. Rheumatology 2008;47:924-5.
    • (2008) Rheumatology , vol.47 , pp. 924-925
    • Chakravarty, K.1    McDonald, H.2    Pullar, T.3
  • 12
    • 33745195677 scopus 로고    scopus 로고
    • Leflunomide-induced pneumonitis in a patient with rheumatoid arthritis
    • Hirabayashi Y, Shimizu H, Kobayashi N, Kudo K. Leflunomide-induced pneumonitis in a patient with rheumatoid arthritis. Intern Med 2006;45:689-91.
    • (2006) Intern Med , vol.45 , pp. 689-691
    • Hirabayashi, Y.1    Shimizu, H.2    Kobayashi, N.3    Kudo, K.4
  • 13
    • 33645306584 scopus 로고    scopus 로고
    • Pneumonitis associated with leflunomide: a profile of New Zealand and Australian reports
    • Savage RL, Highton J, Boyd IW, Chapman P. Pneumonitis associated with leflunomide: a profile of New Zealand and Australian reports. Intern Med J 2006;36:162-9.
    • (2006) Intern Med J , vol.36 , pp. 162-169
    • Savage, R.L.1    Highton, J.2    Boyd, I.W.3    Chapman, P.4
  • 15
    • 34447517421 scopus 로고    scopus 로고
    • Risk of interstitial lung disease associated with leflunomide treatment in Korean patients with rheumatoid arthritis
    • Ju JH, Kim SI, Lee JH et al. Risk of interstitial lung disease associated with leflunomide treatment in Korean patients with rheumatoid arthritis. Arthritis Rheum 2007;56:2094-6.
    • (2007) Arthritis Rheum , vol.56 , pp. 2094-2096
    • Ju, J.H.1    Kim, S.I.2    Lee, J.H.3
  • 16
    • 11344278661 scopus 로고    scopus 로고
    • Rheumatoid arthritis complicated with acute interstitial pneumonia induced by leflunomide as an adverse reaction
    • Kamata Y, Nara H, Kamimura T et al. Rheumatoid arthritis complicated with acute interstitial pneumonia induced by leflunomide as an adverse reaction. Intern Med 2004;43:1201-4.
    • (2004) Intern Med , vol.43 , pp. 1201-1204
    • Kamata, Y.1    Nara, H.2    Kamimura, T.3
  • 17
    • 33750035165 scopus 로고    scopus 로고
    • Leflunomide-related acute interstitial pneumonia in two patients with rheumatoid arthritis: autopsy findings with a mosaic pattern of acute and organizing diffuse alveolar damage
    • Ochi S, Harigai M, Mizoguchi F et al. Leflunomide-related acute interstitial pneumonia in two patients with rheumatoid arthritis: autopsy findings with a mosaic pattern of acute and organizing diffuse alveolar damage. Mod Rheumatol 2006;16:316-20.
    • (2006) Mod Rheumatol , vol.16 , pp. 316-320
    • Ochi, S.1    Harigai, M.2    Mizoguchi, F.3
  • 18
    • 39149137841 scopus 로고    scopus 로고
    • Leflunomide-induced lung injury that developed after its withdrawal, coinciding with peripheral blood lymphocyte count decrease
    • Otsuka T, Koyama T, Ohtani R et al. Leflunomide-induced lung injury that developed after its withdrawal, coinciding with peripheral blood lymphocyte count decrease. Mod Rheumatol 2008;18:96-9.
    • (2008) Mod Rheumatol , vol.18 , pp. 96-99
    • Otsuka, T.1    Koyama, T.2    Ohtani, R.3
  • 20
    • 28544432603 scopus 로고    scopus 로고
    • Lethal pneumonitis under leflunomide therapy
    • Vallbracht II, Popper HH, Rieber J et al. Lethal pneumonitis under leflunomide therapy. Rheumatology 2005;44:1580-1.
    • (2005) Rheumatology , vol.44 , pp. 1580-1581
    • Vallbracht, I.I.1    Popper, H.H.2    Rieber, J.3
  • 21
    • 0023874002 scopus 로고
    • Methotrexate pneumonitis in rheumatoid arthritis: potential risk factors Four case reports and a review of the literature
    • Searles G, McKendry RJ. Methotrexate pneumonitis in rheumatoid arthritis: potential risk factors. Four case reports and a review of the literature. J Rheumatol 1987; 14:1164-71.
    • (1987) J Rheumatol , vol.14 , pp. 1164-1171
    • Searles, G.1    McKendry, R.J.2
  • 22
    • 33846665401 scopus 로고    scopus 로고
    • Pulmonary adverse events with leflunomide-myth or reality?
    • Balakrishnan C, Dasgupta B. Pulmonary adverse events with leflunomide-myth or reality? Rheumatology 2007;46:372-3.
    • (2007) Rheumatology , vol.46 , pp. 372-373
    • Balakrishnan, C.1    Dasgupta, B.2
  • 23
    • 22144446840 scopus 로고    scopus 로고
    • Leflunomide-related lung injury in patients with rheumatoid arthritis: imaging features
    • Sakai F, Noma S, Kurihara Y et al. Leflunomide-related lung injury in patients with rheumatoid arthritis: imaging features. Mod Rheumatol 2005;15:173-9.
    • (2005) Mod Rheumatol , vol.15 , pp. 173-179
    • Sakai, F.1    Noma, S.2    Kurihara, Y.3
  • 24
    • 33745600395 scopus 로고    scopus 로고
    • Drug-related pulmonary problems in patients with rheumatoid arthritis
    • Saravanan V, Kelly C. Drug-related pulmonary problems in patients with rheumatoid arthritis. Rheumatology 2006;45:787-9.
    • (2006) Rheumatology , vol.45 , pp. 787-789
    • Saravanan, V.1    Kelly, C.2
  • 25
    • 11344278662 scopus 로고    scopus 로고
    • Interstitial lung disease associated with leflunomide
    • Ito S, Sumida T. Interstitial lung disease associated with leflunomide. Intern Med 2004;43:1103-4.
    • (2004) Intern Med , vol.43 , pp. 1103-1104
    • Ito, S.1    Sumida, T.2
  • 26
    • 0037809578 scopus 로고    scopus 로고
    • Will pharmacogenetics allow better prediction of methotrexate toxicity and efficacy in patients with RA?
    • Hider SL, Morgan C, Bell E, Bruce IN. Will pharmacogenetics allow better prediction of methotrexate toxicity and efficacy in patients with RA? Ann Rheum Dis 2003; 62:591-2.
    • (2003) Ann Rheum Dis , vol.62 , pp. 591-592
    • Hider, S.L.1    Morgan, C.2    Bell, E.3    Bruce, I.N.4
  • 28
    • 0031837377 scopus 로고    scopus 로고
    • Experience with methotrexate-associated pneumonitis in northeastern England: comment on the article by Kremer et al
    • Bartram SA. Experience with methotrexate-associated pneumonitis in northeastern England: comment on the article by Kremer et al. Arthritis Rheum 1998;41:1327-8.
    • (1998) Arthritis Rheum , vol.41 , pp. 1327-1328
    • Bartram, S.A.1
  • 29
    • 15444350253 scopus 로고    scopus 로고
    • Clinical, laboratory, radiographic, and histopathologic features of methotrexate-associated lung injury in patients with rheumatoid arthritis: a multicenter study with literature review
    • Kremer JM, Alarcon GS, Weinblatt ME et al. Clinical, laboratory, radiographic, and histopathologic features of methotrexate-associated lung injury in patients with rheumatoid arthritis: a multicenter study with literature review. Arthritis Rheum 1997; 40:1829-37.
    • (1997) Arthritis Rheum , vol.40 , pp. 1829-1837
    • Kremer, J.M.1    Alarcon, G.S.2    Weinblatt, M.E.3
  • 30
    • 0022642201 scopus 로고
    • Interstitial pneumonitis after bone marrow transplantation Assessment of risk factors
    • Weiner RS, Bortin MM, Gale RP et al. Interstitial pneumonitis after bone marrow transplantation. Assessment of risk factors. Ann Intern Med 1986;104:168-75.
    • (1986) Ann Intern Med , vol.104 , pp. 168-175
    • Weiner, R.S.1    Bortin, M.M.2    Gale, R.P.3
  • 31
    • 0029993190 scopus 로고    scopus 로고
    • Occurrence of pulmonary complications during methotrexate therapy in rheumatoid arthritis
    • Hilliquin P, Renoux M, Perrot S, Puechal X, Menkes CJ. Occurrence of pulmonary complications during methotrexate therapy in rheumatoid arthritis. Br J Rheumatol 1996;35:441-5.
    • (1996) Br J Rheumatol , vol.35 , pp. 441-445
    • Hilliquin, P.1    Renoux, M.2    Perrot, S.3    Puechal, X.4    Menkes, C.J.5
  • 32
    • 0023143528 scopus 로고
    • Pulmonary disease during the treatment of rheumatoid arthritis with low dose pulse methotrexate
    • Carson CW, Cannon GW, Egger MJ, Ward JR, Clegg DO. Pulmonary disease during the treatment of rheumatoid arthritis with low dose pulse methotrexate. Semin Arthritis Rheum 1987;16:186-95.
    • (1987) Semin Arthritis Rheum , vol.16 , pp. 186-195
    • Carson, C.W.1    Cannon, G.W.2    Egger, M.J.3    Ward, J.R.4    Clegg, D.O.5
  • 33
    • 15444350253 scopus 로고    scopus 로고
    • Clinical, laboratory, radiographic, and histopathologic features of methotrexate-associated lung injury in patients with rheumatoid arthritis: a multicenter study with literature review
    • Kremer JM, Alarcon GS, Weinblatt ME et al. Clinical, laboratory, radiographic, and histopathologic features of methotrexate-associated lung injury in patients with rheumatoid arthritis: a multicenter study with literature review. Arthritis Rheum 1997;40:1829-37.
    • (1997) Arthritis Rheum , vol.40 , pp. 1829-1837
    • Kremer, J.M.1    Alarcon, G.S.2    Weinblatt, M.E.3
  • 34
    • 0023874002 scopus 로고
    • Methotrexate pneumonitis in rheumatoid arthritis: potential risk factors Four case reports and a review of the literature
    • Searles G, McKendry RJ. Methotrexate pneumonitis in rheumatoid arthritis: potential risk factors. Four case reports and a review of the literature. J Rheumatol 1987; 14:1164-71.
    • (1987) J Rheumatol , vol.14 , pp. 1164-1171
    • Searles, G.1    McKendry, R.J.2
  • 35
    • 54449098254 scopus 로고    scopus 로고
    • Variation of immunological response in methotrexate-induced pneumonitis
    • Chikura B, Sathi N, Lane S, Dawson JK. Variation of immunological response in methotrexate-induced pneumonitis. Rheumatology 2008;47:1647-50.
    • (2008) Rheumatology , vol.47 , pp. 1647-1650
    • Chikura, B.1    Sathi, N.2    Lane, S.3    Dawson, J.K.4
  • 36
    • 0029618714 scopus 로고    scopus 로고
    • Long-term tolerability of methotrexate at doses exceeding 15mg per week in rheumatoid arthritis
    • Schnabel A, Herlyn K, Burchardi C, Reinhold-Keller E, Gross WL. Long-term tolerability of methotrexate at doses exceeding 15mg per week in rheumatoid arthritis. Rheumatol Int 1996;15:195-200.
    • (1996) Rheumatol Int , vol.15 , pp. 195-200
    • Schnabel, A.1    Herlyn, K.2    Burchardi, C.3    Reinhold-Keller, E.4    Gross, W.L.5
  • 37
    • 0034895195 scopus 로고    scopus 로고
    • Fibrosing alveolitis in patients with rheumatoid arthritis as assessed by high resolution computed tomography, chest radiography, and pulmonary function tests
    • Dawson JK, Fewins HE, Desmond J, Lynch MP, Graham DR. Fibrosing alveolitis in patients with rheumatoid arthritis as assessed by high resolution computed tomography, chest radiography, and pulmonary function tests. Thorax 2001;56:622-7.
    • (2001) Thorax , vol.56 , pp. 622-627
    • Dawson, J.K.1    Fewins, H.E.2    Desmond, J.3    Lynch, M.P.4    Graham, D.R.5
  • 38
    • 33646479007 scopus 로고    scopus 로고
    • Leflunomide use and the risk of interstitial lung disease in rheumatoid arthritis
    • Suissa S, Hudson M, Ernst P. Leflunomide use and the risk of interstitial lung disease in rheumatoid arthritis. Arthritis Rheum 2006;54:1435-9.
    • (2006) Arthritis Rheum , vol.54 , pp. 1435-1439
    • Suissa, S.1    Hudson, M.2    Ernst, P.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.