Serum catalytic iron as a novel biomarker of vascular injury in acute coronary syndromes

EuroIntervention

Volumn 5, Issue 3, 2009, Pages 336-342

  Lele, Suhas ^a   Shah, Sudhir ^b   McCullough, Peter A ^c   Rajapurkar, Mohan ^d  

^a Bhailal Amin General Hospital   (India)

^b UNIVERSITY OF ARKANSAS FOR MEDICAL SCIENCES   (United States)

^c WILLIAM BEAUMONT HOSPITAL   (United States)

^d MULJIBHAI PATEL UROLOGICAL HOSPITAL   (India)

Author keywords

Biochemical markers; Non STEMI; Plaque rupture

Indexed keywords

CATALYTIC IRON; IRON; TROPONIN I; UNCLASSIFIED DRUG; BIOLOGICAL MARKER;

ACUTE CORONARY SYNDROME; ACUTE HEART INFARCTION; ADULT; ARTICLE; BLOOD VESSEL INJURY; CONTROLLED STUDY; DIAGNOSTIC ACCURACY; DIAGNOSTIC VALUE; FEMALE; HUMAN; IRON BLOOD LEVEL; MAJOR CLINICAL STUDY; MALE; PROGNOSIS; SENSITIVITY AND SPECIFICITY; ANGINA PECTORIS; BLOOD; CASE CONTROL STUDY; EVALUATION; HEART INFARCTION; PREDICTION AND FORECASTING; RISK ASSESSMENT; ROC CURVE; STATISTICAL MODEL; TIME; UPREGULATION;

ACUTE CORONARY SYNDROME; ANGINA PECTORIS; BIOLOGICAL MARKERS; CASE-CONTROL STUDIES; HUMANS; IRON; LOGISTIC MODELS; MYOCARDIAL INFARCTION; PREDICTIVE VALUE OF TESTS; RISK ASSESSMENT; ROC CURVE; SENSITIVITY AND SPECIFICITY; TIME FACTORS; TROPONIN I; UP-REGULATION;

EID: 70349783080     PISSN: 1774024X     EISSN: 19696213     Source Type: Journal    
DOI: 10.4244/V5I3A53     Document Type: Article

References (31)

1. Hamm CW, Heeschen C, Goldmann B, Vahanian A, Adgey J, Miguel CM, Rutsch W, Berger J, Kootstra J, Simmons ML. For the c7E3 Fab Antiplatelet Therapy in Unstable Refractory Angina (CAPTURE) Study Investigators. Benefit of abciximab in patients with refractory unstable angina in relation to serum troponin T levels. N Engl J Med. 1999;340:1623-1629.
2. Morrow DA, Antman EM, Tanasijevic M, Rifai N, de Lemos JA, McCabe CH, Cannon CP, Braunwald E. Cardiac troponin I for stratification of early outcomes and the efficacy of enoxaparin in unstable angina: a TIMI 11B substudy. J Am Coll Cardiol. 2000;36:1812-1817.
3. Cannon CP, Weintraub WS, Demopoulos LA, Vicari R, Frey MJ, Lakkis N, Neumann FJ, Robertson DH, DeLucca PT, DiBattistie PM, Gibson M, Braunwald E. For the TACTICS-Thrombolysis in Myocardial Infarction 18 Investigators. Comparison of early invasive and conservative strategies in patients with unstable coronary syndromes treated with the glycoprotein IIb/IIIa inhibitor tirofiban. N Engl J Med. 2001;344:1879-1887. (Pubitemid 32564900)
4. Braunwald E, Antman EM, Beasley JW, Califf RM, Cheitlin MD, Hochman JS, Jones RH, Kereiakes D, Kupersmith J, Levine TN, Pepine CJ, Schaeffer JW, Smith III EE, Steward DE, Theroux P. ACC/AHA guidelines for the management of patients with unstable angina and non-ST-segment elevation myocardial infarction: a report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines. J Am Coll Cardiol. 2000;36:970-1062.
5. Hamm CW, Goldmann BU, Heeschen C, Kreymann G, Berger J, Meinertz T. Emergency room triage of patients with acute chest pain by means of rapid testing for cardiac troponin T or troponin I. N Engl J Med. 1997;337:1648-1653. (Pubitemid 27510101)
6. Zimmerman J, Fromm R, Meyer D, Boudreaux A, Wun CC, Smalling R, Davis B, Habib G, Roberts R. Diagnostic marker cooperative study for the diagnosis of myocardial infarction. Circulation. 1999;99:1671-7. (Pubitemid 29162478)
7. Miller CD, Banerjee A, Mahaffey KW, Kontos MC, Fermann G, Pollack Jr CV, Antman E, Alyward P, Goodman SG, Santos R, Ferguson JJ, Califf RM, Hoekstra JW, Treatment and outcomes of patients with evolving myocardial infarction: experiences from the SYNERGY trial. Eur Heart J. 2007;28:1079-1084. (Pubitemid 47343864)
8. Roe MT, Peterson ED, Pollack CV Jr, Newby LK, Li Y, Christenson RH, Peacock WF, Fesmire FM, Diercks D, Kirk JD, Smith Jr SC, Ohman EM, Gibler WB. For the CRUSADE Investigators. Influence of timing of troponin elevation on clinical outcomes and use of evidence-based therapies for patients with non-ST-segment elevation acute coronary syndromes. Ann Emerg Med. 2005;45:355-362.
9. Halliwell B, Gutteridge JM: Role of free radicals and catalytic metal ions in human disease: an overview. Meth Enz. 1990;186:1-85. (Pubitemid 20279941)
10. Kakhlon O, Cabantchik ZI. The labile iron pool: characterization, measurement, and participation in cellular processes. Free Rad Biol Med. 2002;33:1037-1046.
11. Kruszewski M. Labile iron pool: the main determinant of cellular response to oxidative stress. Mutat Research. 2003;531:81-92. (Pubitemid 37456724)
12. Ueda N, Mayeux PR, Baliga R, Shah SV. Oxidant mechanisms in acute renal failure. In: Molitoris B, Finn W (eds) Acute Renal Failure: A Companion to Brenner & Rector's The Kidney. W. B. Saunders Company: Philadelphia, 2001, pp 60-77.
13. Shah SV, Baliga R, Fonseca VA, Rajapurkar M. Oxidants in chronic kidney disease. J Am Soc Nephrol. 2007;18:16-28. (Pubitemid 46053418)
14. Shah SV, Rajapurkar MM, Houser M. The role of labile iron in acute kidney injury. US Nephrol. 2008;3:52-55.
15. Voogd A, Sluiter W, van Eijk HG, Koster JF. Low molecular weight iron and the oxygen paradox in isolated rat hearts. J Clin Invest. 1992;90:2050-2055.
16. Paraskevaidis JA, Iliodromitis EK, Vlahakos D, Tsiapras DP, Nikolaidis A, Marathias A, Michalis A, Kremastinos D Th. Desferoxamine infusion during coronary artery bypass grafting ameliorates lipid peroxidation and protects the myocardium against reperfusion injury: immediate and long-term significance. Euro Heart J. 2005;26:263-70. (Pubitemid 40227432)
17. Boddaert N, Le Quan Sang KH, Rötig A, Leroy-Willig A, Gallet S, Brunelle F, Sidi D, Thalabard JC, Munnich A, Cabantchik Z. Selective iron chelation in Friedreich ataxia: biologic and clinical implications. Blood. 2007;110:401-8. (Pubitemid 47026862)
18. Thygesen K, Alpert JS, White HD. Universal definition of Myocardial Infarction. J.Am.Coll.Cardiol. 2007;50:2173-95. (Pubitemid 350123680)
19. Evans PJ, Halliwell B. Measurement of iron and copper in biological systems: bleomycin and copper-phenanthroline assays. Meth Enzymol. 1994;233:82-92.
20. LaDue JS, Wrobleski F, Karmen A. Serum glutamic oxaloaxetic transaminase activity in human acute transmural myocardial infarction. Science. 1954;120:497.
21. Kemp M, Donovan J, Higham H, Hooper J. Biochemical markers of myocardial injury. Br J Anaesth. 2004 Jul;93:63-73. (Pubitemid 38967429)
22. Maisel AS, Krishnaswamy P, Nowak RM, McCord J, Hollander JE, Duc P, Omland T, Storrow AB, Abraham WT, Wu AHB, Clopton P, Steg PG, Westheim A, Knudsen CW, Perez A, Kazanegra R, Herrmann HC, McCullough PA. Rapid measurement of B-type natriuretic peptide in the emergency diagnosis of heart failure. New Engl J Med. 2002;347:161-167. (Pubitemid 34764819)
23. deLemos JA, Morrow DA, Bentley JH, Olmand T, Sabatine MS, McCabe CH, Hall C, Cannon CP, Braunwald E. The prognostic value of Btype natriuretic peptide in patients with acute coronary syndrome. New Engl J Med. 2001;345:1014-1021.
24. Sullivan JL. Iron and the sex difference in heart disease risk. Lancet. 1981;1:1293-1294. (Pubitemid 11111356)
25. Maggi E, Chiesa R, Melissano G, Astore D, Grossi A, Finardi G, Billomo G. LDL oxidation in patients with severe carotid atherosclerosis: a study of in vitro and in vivo oxidation markers. Arterioscler Thromb. 1994;14:1892-1899.
26. Laurindo FR, da Luz PL, Uint L, Rocha TF, Jaeger RG, Lopes EA. Evidence for superoxide radical-dependent coronary vasospasm after angioplasty in intact dogs. Circulation. 1991 May;83:1705-15.
27. Stocker R, Keaney JF Jr. Role of oxidative modifications in atherosclerosis. Physiol Rev. 2004 Oct;84:1381-478. (Pubitemid 39302636)
28. Valgimigli M, Agnoletti L, Curello S, Comini L, Francolini G, Mastrorilli F, Merli E, Pirani R, Guardigli G, Grigolato PG, Ferrari R. Serum from patients with acute coronary syndromes displays a proapoptotic effect on human endothelial cells: a possible link to pan-coronary syndromes. Circulation. 2003 Jan 21;107:264-70. (Pubitemid 36135222)
29. Jain VK, Mohan G. Serum zinc and copper in myocardial infarction with particular reference to prognosis. Biol Trace Elem Res. 1991;31:317-322.
30. Katayama T, Honda Y, Yamasaki H, Kitamura S, Okano Y. Serum zinc concentration in acute myocardial infarction. Angiology. 1990;41:479-485. (Pubitemid 20222139)
31. Evans PJ, Smith C, Mitchinson MJ, Halliwell B. Metal ion release from mechanically disrupted human arterial wall. Implications for the development of atherosclerosis. Free Radic Res 1995;23:465-469.