Donor pretreatment with hypertonic saline attenuates primary allograft dysfunction A pilot study in a porcine model

Circulation

Volumn 120, Issue SUPPL. 1, 2009, Pages

  Badiwala, Mitesh V ^a   Ramzy, Danny ^a   Tumiati, Laura C ^a   Tepperman, Elissa D ^a   Sheshgiri, Rohit ^a   Prodger, Jessica L ^a   Feindel, Christopher M ^a   Rao, Vivek ^a,b  

^a TORONTO GENERAL HOSPITAL   (Canada)

^b UNIVERSITY OF TORONTO   (Canada)

Author keywords

Endothelium; Ischemia; Reperfusion; Transplantation

Indexed keywords

SODIUM; SODIUM CHLORIDE; CYTOKINE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CRYOPRESERVATION; FEMALE; GRAFT DYSFUNCTION; GRAFT PRESERVATION; HEART TRANSPLANTATION; NONHUMAN; ORGAN DONOR; ORTHOTOPIC TRANSPLANTATION; PILOT STUDY; POSTOPERATIVE COMPLICATION; PRIORITY JOURNAL; SODIUM BLOOD LEVEL; SOW (SWINE); SYSTOLIC BLOOD PRESSURE; ALLOTRANSPLANTATION; ANIMAL; BLOOD; CARDIOPULMONARY BYPASS; DONOR; HEART LEFT VENTRICLE FUNCTION; MORTALITY; PHYSIOLOGY; SWINE; VASCULAR ENDOTHELIUM;

ANIMALS; CARDIOPULMONARY BYPASS; CYTOKINES; ENDOTHELIUM, VASCULAR; FEMALE; HEART TRANSPLANTATION; MODELS, ANIMAL; PRIMARY GRAFT DYSFUNCTION; SALINE SOLUTION, HYPERTONIC; SODIUM; SWINE; TISSUE DONORS; TRANSPLANTATION, HOMOLOGOUS; VENTRICULAR FUNCTION, LEFT;

EID: 70349782858     PISSN: 00097322     EISSN: 15244539     Source Type: Journal    
DOI: 10.1161/CIRCULATIONAHA.108.843169     Document Type: Article

References (28)

1. Wildhirt SM, Weis M, Schulze C, Conrad N, Rieder G, Enders G, Hinken K, von Scheidt W, Reichart B. Effects of Celsior and University of Wisconsin preservation solutions on hemodynamics and endothelial function after cardiac transplantation in humans: a single-center, prospective, randomized trial. Transpl Int. 2000;13(Suppl 1):S203-S211.
2. Pascual JL, Khwaja KA, Ferri LE, Giannias B, Evans DC, Razek T, Michel RP, Christou NV. Hypertonic saline resuscitation attenuates neutrophil lung sequestration and transmigration by diminishing leukocyteendothelial interactions in a two-hit model of hemorrhagic shock and infection. J Trauma. 2003;54:121-130; discussion 130-132
3. 3. Rizoli SB, Kapus A, Parado J, Fan J, Rotstein OD. Hypertonic immunomodulation is reversible and accompanied by changes in CDl lb expression. J Surg.Res. 1999;83:130-135. (Pubitemid 29391618)
4. Rizoli SB, Kapus A, Parodo J, Rotstein OD. Hypertonicity prevents lipopolysaccharide-stimulated CD11b/CD18 expression in human neutrophils in vitro: role for p38 inhibition. J Trauma. 1999;46:794-798; discussion 798-799
5. 5. Cuschieri J, Gourlay D, Garcia I, Jelacic S, Maier RV. Hypertonic preconditioning inhibits macrophage responsiveness to endotoxin. J Immunol. 2002;168:1389-1396. (Pubitemid 34094510)
6. 6. Waagstein LM, Wennberg E, Waagstein F, Haljamae H. Hypertonie saline without or with dextran-70 in the treatment of experimental acute myocardial ischemia and reperfusion. Crit Care Med. 1999;27:605-616. (Pubitemid 29162684)
7. 7. Rao V, Feindel CM, Weisel RD, Boylen P, Cohen. G. Donor blood perfusion improves myocardial recovery after heart transplantation. J Heart Lung Transplant. 1997;16:667-673. (Pubitemid 27311360)
8. 8. Baan J, van der Velde ET, de Bruin HG, Smeenk GJ, Koops J, van Dijk AD, Temmerman D, Senden J, Buis B. Continuous measurement of left ventricular volume in animals and humans by conductance catheter. Circulation. 1984;70:812-823. (Pubitemid 15205446)
9. 9. Szwarc RS, Mickleborough LL, Mizuno S, Wilson GJ, Liu P, Mohamed S. Conductance catheter measurements of left ventricular volume in the intact dog: parallel conductance is independent of left ventricular size. Cardiovasc Res. 1994;28:252-258. (Pubitemid 24092776)
10. 10. Jeanmart H, Malo O, Carrier M, Nickner C, Desjardins N, Perrault LP. Comparative study of cyclosporine and tacrolimus vs newer immunosuppressants mycophenolate mofetil and rapamycin on coronary endothelial function. J Heart Lung Transplant. 2002;21:990-998. (Pubitemid 35286683)
11. Taylor DO, Edwards LB, Aurora P, Christie JD, Dobbels F, Kirk R, Rahmel AO, Kucheryavaya AY, Hertz MI. Registry of the International Society for Heart and Lung Transplantation: twenty-fifth official adult heart transplant report-2008. J Heart Lung Transplant. 2008;27:943-956.
12. Kaufman C., Zeevi A, Zerbe T, Keenan R, Kormos R, Griffith B, Hardesty R, Armitage J, Uretsky B, Duquesnoy RJ. In vitro culture of infiltrating lymphocytes from, coronary arteries and endomyocardial biopsies: association with graft coronary disease. Transplant Proc. 1991;23: 1142-1143.
13. McEver RP, Moore KL, Cummings RD. Leukocyte trafficking mediated by selectin-carbohydrate interactions. J Biol Chem. 1995;270: 11025-11028.
14. 14. Ma XL, Weyrich AS, Lefer DJ, Lefer AM. Diminished basal nitric oxide release after myocardial ischemia and reperfusion promotes neutrophil adherence to coronary endothelium. Circ Res. 1993;72:403-412. (Pubitemid 23024528)
15. Ginis I, Mentzer SJ, Li X, Faller DV. Characterization of a hypoxiaresponsive adhesion molecule for leukocytes on human endothelial cells. J Immunol. 1995;155:802-810.
16. 16. Bulger EM, Jurkovich GJ, Nathens AB, Copass MK, Hanson S, Cooper C, Liu PY, Neff M, Awan AB, Warner K, Maier RV. Hypertonic resus- citation of hypovolemic shock after blunt trauma: a randomized controlled trial. Arch Surg. 2008;143:139-148, discussion 149. (Pubitemid 351281617)
17. 17. Rizoli SB, Rhind SG, Shek PN, Inaba K, Filips D, Tien H, Brenneman F, Rotstein O. The immunomodulatory effects of hypertonic saline resuscitation in patients sustaining traumatic hemorrhagic shock: a randomized, controlled, double-blinded trial. Ann Surg. 2006;243:47-57. (Pubitemid 43054054)
18. Boldt J, Zickmann B, Ballesteros M, Herold C, Dapper F, Hempelmann G. Cardiorespiratory responses to hypertonic saline solution in cardiac operations. Ann Thorac Surg. 1991;51:610-615.
19. 19. Mazhar R, Samenesco A, Royston D, Rees A. Cardiopulmonary effects of 7.2% saline solution compared with gelatin infusion in the early postoperative period after coronary artery bypass grafting. J Thorac Cardiovasc Surg. 1998;115:178-189. (Pubitemid 28082164)
20. 20. Kusuoka H, Camilion de Hurtado MC, Marban E. Role of sodium/ calcium exchange in the mechanism of myocardial stunning: protective effect of reperfusion with high sodium, solution. J Am Coll Cardiol. 1993;21:240-248. (Pubitemid 23031322)
21. 21. Sidi A, Muehlschlegel JD, Kirby DS, Kirby RR, Lobato EB. Treating ischemic left ventricular dysfunction with hypertonic saline administered after coronary occlusion in pigs. J Cardiothorac Vase Anesth. 2007;21: 400-405. (Pubitemid 46829892)
22. 22. Ryan JB, Hicks M, Cropper JR, Garlick SR, Kesteven SH, Wilson MK, Macdonald PS, Feneley MP. The preload recruitable stroke work relationship as a measure of left ventricular contractile dysfunction in porcine cardiac allografts. Eur J Cardiothorac Surg. 2002;22:738-745. (Pubitemid 35303362)
23. Tanaka H, Swanson SJ, Sukhova G, Schoen FJ, Libby P. Smooth muscle cells of the coronary arterial tunica media express tumor necrosis factor-alpha and proliferate during acute rejection of rabbit cardiac allografts. Am J Pathol. 1995;147:617-626.
24. Oreopoulos GD, Hamilton J, Rizoli SB, Fan J, Lu Z, Li YH, Marshall JC, Kapus A1 Rotstein OD. In vivo and in vitro modulation, of intercellular adhesion molecule (ICAM)-1 expression by hypertonicity. Shock. 2000; 14:409-414; discussion 414-415
25. Zakaria el R, Tsakadze NL, Garrison RN. Hypertonic saline resuscitation improves intestinal microcirculation in a rat model of hemorrhagic shock. Surgery. 2006;140:579-587; discussion 587-588
26. 26. Totsuka E, Dodson F, Urakami A, Moras N, Ishii T, Lee MC, Gutierrez J1 Gerardo M, Molmenti E, Fung JJ. Influence of high donor serum, sodium levels on early postoperative graft function in human liver transplantation: effect of correction of donor hypematremia. Liver Transpl Surg. 1999;5:421-428. (Pubitemid 29437020)
27. 27. Totsuka E, Fung U, Hakamada K, Tanaka M, Takahashi K, Nakai M, Morohashi S, Nishimura A, Ishizawa Y, Ono H, Toyoki Y, Narumi S, Sasaki M. Analysis of clinical variables of donors and recipients with, respect to short-term graft outcome in human liver transplantation. Transplant Proc. 2004;36:2215-2218. (Pubitemid 39550791)
28. 28. Jawan B, Goto S, Lai CY, De Villa VH, Luk HN, Eng HL, Chen YS, Wang CC, Cheng YF, Chen CL. The effect of hypematremia on liver allografts in rats. Anesth Analg. 2002;95:1169-1172. (Pubitemid 35239099)