Fragmentation and plasmid strand breaks in pure and gold-doped DNA irradiated by beams of fast hydrogen atoms

Physics in Medicine and Biology

Volumn 54, Issue 15, 2009, Pages 4705-4721

  Wyer, J A ^a   Butterworth, K T ^a   Hirst, D G ^a   Latimer, C J ^a   Montenegro, E C ^b   Shah, M B ^a   Currell, F J ^a  

^a QUEEN'S UNIVERSITY BELFAST   (United Kingdom)

^b FEDERAL UNIVERSITY OF RIO DE JANEIRO   (Brazil)

Author keywords

[No Author keywords available]

Indexed keywords

AGAROSE GEL ELECTROPHORESIS; BEAM ENERGIES; DAMAGE LEVEL; DNA DAMAGES; DNA SAMPLES; DOUBLE STRAND BREAKS; GOLD NANOPARTICLES; HYDROGEN ATOMS; ION FLUXES; MICA SUBSTRATES; PER UNIT; PLASMID DNA; SAMPLE PREPARATION; SAMPLE STRUCTURE; STRAND BREAKS;

DNA; ELECTROPHORESIS; FREE RADICALS; GENES; GOLD; MICA; NANOPARTICLES; SILICATE MINERALS;

NUCLEIC ACIDS;

GOLD NANOPARTICLE; HYDROGEN; MICA; PLASMID DNA; BUFFER; DNA; GOLD; METAL NANOPARTICLE; PROTON;

AGAR GEL ELECTROPHORESIS; ARTICLE; DNA DAMAGE; ION CURRENT; IRRADIATION; PLASMID; PRIORITY JOURNAL; BIOLOGICAL MODEL; CHEMISTRY; DNA STRAND BREAKAGE; DRUG EFFECT; ELECTRON; GENETICS; KINETICS; RADIATION EXPOSURE; RADIATION RESPONSE;

BUFFERS; DNA; DNA BREAKS; DOSE-RESPONSE RELATIONSHIP, RADIATION; ELECTRONS; GOLD; HYDROGEN; KINETICS; METAL NANOPARTICLES; MODELS, BIOLOGICAL; PLASMIDS; PROTONS;

EID: 70349769651     PISSN: 00319155     EISSN: 13616560     Source Type: Journal    
DOI: 10.1088/0031-9155/54/15/005     Document Type: Article

References (40)

1. Biston M C, Joubert A, Adam J F, Elleaume H, Bohic S, Charvet A M, Esteve F, Foray N and Balosso J 2004 Cure of fisher rats bearing radioresistant F98 glioma treated with cis-platinum and irradiated with monochromatic synchrotron x-rays Cancer Res. 64 2317-23
2. Boudaffa B, Cloutier P, Hunting D, Huels M A and Sanche L 2002 Cross sections for low-energy (10-50 eV) electron damage to DNA Radiat. Res. 157 227-34
3. Bragg W H and Kleemann R 1905 On the alpha particles of radium, and their loss of range in passing through various atoms and molecules Phil. Mag. S.6 10 318-40
4. Butterworth K T, Wyer J A, Brennan-Fournet M, Latimer C J, Shah M B, Currell F J and Hirst D G 2008 Variation of strand break yield for plasmid DNA irradiated with high-Z metal nanoparticles Radiat. Res. 170 381-7
5. Carter J D, Cheng N N, Qu Y Q, Suarez G D and Guo T 2007 Nanoscale energy deposition by x-ray absorbing nanostructures J. Phys. Chem. B 111 11622-5
6. Cho S H 2005 Estimation of tumour dose enhancement due to gold nanoparticles during typical radiation treatments: a preliminary Monte Carlo study Phys. Med. Biol. 50 N163-73
7. Deng Z W, Bald I, Illenberger E and Huels M A 2005 Beyond the Bragg peak: hyperthermal heavy ion damage to DNA components Phys. Rev. Lett. 95 4
8. Folkard M, Prise K M, Brocklehurst B and Michael B D 1999 DNA damage induction in dry and hydrated DNA by synchrotron radiation J. Phys. B: At. Mol. Opt. Phys. 32 2753-61
9. Folkard M, Prise K M, Vojnovic B, Brocklehurst B and Michael B D 2000 Critical energies for ssb and dsb induction in plasmid DNA by vacuum-UV photons: an arrangement for irradiating dry or hydrated DNA with monochromatic photons Int. J. Radiat. Biol. 76 763-71 (Pubitemid 30352759)
10. Friedland W, Dingfelder M, Jacob P and Paretzke H G 2005 Calculated DNA double-strand break and fragmentation yields after irradiation with He ions Radiat. Phys. Chem. 72 279-86
11. Friedland W, Jacob P, Bernhardt P, Paretzke H G and Dingfelder M 2003 Simulation of DNA damage after proton irradiation Radiat. Res. 159 401-10
12. Grande P L and Schiwietz G 2002 The unitary convolution approximation for heavy ions Nucl. Instrum. Methods Phys. Res. B 195 55-63
13. Hada M and Georgakilas A G 2008 Formation of clustered DNA damage after high-LET irradiation: a review J. Radiat. Res. 49 203-10
14. Hainfeld J F, Slatkin D N and Smilowitz H M 2004 The use of gold nanoparticles to enhance radiotherapy in mice Phys. Med. Biol. 49 N309-N15
15. Herold D M, Das I J, Stobbe C C, Iyer R V and Chapman J D 2000 Gold microspheres: a selective technique for producing biologically effective dose enhancement Int. J. Radiat. Biol. 76 1357-64
16. Huels M A, Boudaffa B, Cloutier P, Hunting D and Sanche L 2003 Single, double, and multiple double strand breaks induced in DNA by 3-100 eV electrons J. Am. Chem. Soc. 125 4467-77
17. Hunniford C A, Timson D J, Davies R J H and McCullough R W 2007 Damage to plasmid DNA induced by low energy carbon ions Phys. Med. Biol. 52 3729-40
18. Kassis A I, Harapanhalli R S and Adelstein S J 1999 Comparison of strand breaks in plasmid DNA after positional changes of auger electron-emitting iodine-125 Radiat. Res. 151 167-76
19. Kobayashi K, Usami N, Sasaki I, Frohlich H and Le Sech C 2003 Study of Auger effect in DNA when bound to molecules containing platinum. A possible application to hadrontherapy Nucl. Instrum. Methods Phys. Res. 199 348-55
20. Le Sech C, Takakura K, Saint-Marc C, Frohlich H, Charlier M, Usami N and Kobayashi K 2000 Strand break induction by photoabsorption in DNA-bound molecules Radiat. Res. 153 454-8
21. Luna H et al 2007a Water-molecule dissociation by proton and hydrogen impact Phys. Rev. A 75 042711
22. Luna H et al 2007b Water-molecule dissociation by proton and hydrogen impact Virt. J. Biol. Phys. Res. 13 9
23. Martin F, Burrow P D, Cai Z L, Cloutier P, Hunting D and Sanche L 2004 DNA strand breaks induced by 0-4 eV electrons: the role of shape resonances Phys. Rev. Lett. 93 068101
24. Mathematica 2001 Mathematica version 4.1 Wolfram Research Inc.
25. Matlab 2002 Matlab 6.5 The MathWorks Inc.
26. Matsudaira H, Ueno A M and Furuno I 1980 Iodine contrast-medium sensitizes cultured mammalian-cells to x-rays but not to gamma-rays Radiat. Res. 84 144-8
27. McMahon S J, Mendenhall M H, Jain S and Currell F 2008 Radiotherapy in the presence of contrast agents: a general figure of merit and its application to gold nanoparticles Phys. Med. Biol. 53 5635-51
28. Mello R S, Callisen H, Winter J, Kagan A R and Norman A 1983 Radiation-dose enhancement in tumors with iodine Med. Phys. 10 75-8
29. Milligan J R, Aguilera J A and Ward J F 1993 Variation of single-strand break yield with scavenger concentration for plasmid DNA irradiated in aqueous-solution Radiat. Res. 133 151-7
30. Nath R, Bongiorni P and Rockwell S 1990 Iododeoxyuridine radiosensitization by low-energy and high-energy photons for brachytherapy dose-rates Radiat. Res. 124 249-58
31. Norman A, Ingram M, Skillen R G, Freshwater D B, Iwamoto K S and Solberg T 1997 X-ray phototherapy for canine brain masses Radiat. Oncol. Investig. 5 8-14
32. Pan X, Cloutier P, Hunting D and Sanche L 2003 Dissociative electron attachment to DNA Phys. Rev. Lett. 90 208102
33. Prelec K 1997 Ions and ion accelerators for cancer treatment Fizika B 6 177-206
34. Regulla D F, Hieber L B and Seidenbusch M 1998 Physical and biological interface dose effects in tissue due to x-ray-induced release of secondary radiation from metallic gold surfaces Radiat. Res. 150 92-100
35. Robar J L, Riccio S A and Martin M A 2002 Tumour dose enhancement using modified megavoltage photon beams and contrast media Phys. Med. Biol. 47 2433-49
36. Rose J H, Norman A, Ingram M, Aoki C, Solberg T and Mesa A 1999 First radiotherapy of human metastatic brain tumors delivered by a computerized tomography scanner (CTRx) Int. J. Radiat. Oncol. Biol. Phys. 45 1127-32
37. Swarts S G, Sevilla M D, Becker D, Tokar C J and Wheeler K T 1992 Radiation-induced DNA damage as a function of hydration: 1. Release of unaltered bases Radiat. Res. 129 333-44
38. Usami N, Furusawa Y, Kobayashi K, Lacombe S, Reynaud-Angelin A, Sage E, Wu T D, Croisy A, Guerquin-Kern J L and Le Sech C 2008 Mammalian cells loaded with platinum-containing molecules are sensitized to fast atomic ions Int. J. Radiat. Biol. 84 603-11
39. Zheng Y, Hunting D J, Ayotte P and Sanche L 2008 Radiosensitization of DNA by gold nanoparticles irradiated with high-energy electrons Radiat. Res. 169 19-27
40. Zheng Y, Wagner J R and Sanche L 2006 DNA damage induced by low-energy electrons: electron transfer and diffraction Phys. Rev. Lett. 96 208101