Albumin from human serum does not contain asymmetric dimethylarginine (ADMA)

Clinical Biochemistry

Volumn 42, Issue 16-17, 2009, Pages 1739-1740

  Tsikas, Dimitrios ^a   Beckmann, Bibiana ^a  

^a HANNOVER MEDICAL SCHOOL   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

ALBUMIN; AMINO ACID; N(G),N(G) DIMETHYLARGININE; NITRIC OXIDE SYNTHASE;

BLOOD STORAGE; CARDIOVASCULAR RISK; CENTRIFUGATION; ENZYME INHIBITION; HUMAN; LETTER; PRIORITY JOURNAL; PROTEIN ANALYSIS; SERUM; URINARY EXCRETION;

ARGININE; HUMANS; SERUM ALBUMIN;

EID: 70349764307     PISSN: 00099120     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.clinbiochem.2009.07.024     Document Type: Letter

References (9)

1. Zinellu A., Sotgia S., Scanu B., et al. Determination of protein-incorporated methylated arginine reference values in healthy subjects whole blood and evaluation of factors affecting protein methylation. Clin. Biochem. 41 (2008) 1218-1223
2. Lenzen H., Tsikas D., and Böger R.H. Asymmetric dimethylarginine (ADMA) and the risk for coronary heart disease. The multicenter CARDIAC study. Eur. J. Clin. Pharmacol. 62 (2006) 45-49
3. Leiper J.M., and Vallance P. The synthesis and metabolism of asymmetric dimethylarginine (ADMA). Eur. J. Clin. Pharmacol. 62 (2006) 33-38
4. Tsikas D., Thum T., Becker T., et al. Accurate quantification of dimethylamine (DMA) in human urine by gas chromatography-mass spectrometry as pentafluorobenzamide derivative: evaluation of the relationship between DMA and its precursor asymmetric dimethylarginine (ADMA) in health and disease. J. Chromatogr. B 851 (2007) 229-239
5. Zinellu A., Sotgia S., Scanu B., et al. Assessment of protein-incorporated arginine methylation in biological specimens by CZE UV-detection. Electrophoresis 28 (2007) 4452-4458
6. Tsikas D. A critical review and discussion of analytical methods in the L-arginine/nitric oxide area of basic and clinical research. Anal. Biochem. 379 (2008) 139-163
7. Tsikas D., Schubert B., Gutzki F.M., et al. Quantitative determination of circulating and urinary asymmetric dimethylarginine (ADMA) in humans by gas chromatography-tandem mass spectrometry as methyl ester tri(N-pentafluoropropionyl) derivative. J. Chromatogr. B 798 (2003) 87-99
8. Maas R., Tan-Andreesen J., Schwedhelm A., et al. A stable-isotope based technique fort he determination of dimethylarginine dimethylaminohydrolase (DDAH) activity in mouse tissue. J. Chromatogr. B 851 (2007) 220-228
9. Tsikas D., and Chobanyan K. Pitfalls in the measurement of DDAH activity: is DDAH sensitive to nitrosative and oxidative stress?. Kidney Int. 74 (2008) 969