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Volumn 1216, Issue 44, 2009, Pages 7472-7477
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Novel monolithic enzymatic microreactor based on single-enzyme nanoparticles for highly efficient proteolysis and its application in multidimensional liquid chromatography
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Author keywords
Monolithic enzymatic microreactor; Multidimensional liquid chromatography; Proteolysis; Proteome
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Indexed keywords
ACRYLAMIDES;
BOVINE SERUM ALBUMINS;
CROSSLINKER;
DATABASE SEARCHES;
DIGESTION PRODUCTS;
FREE RADICAL COPOLYMERIZATION;
FUSED-SILICA CAPILLARIES;
FUTURE APPLICATIONS;
HUMAN LIVER;
IN-SITU;
INNER WALLS;
MALDI TOF MS;
MATRIX-ASSISTED LASER DESORPTION/IONIZATION TIME-OF-FLIGHT;
METHYLENE BISACRYLAMIDE;
MICRO-REACTOR;
MODEL PROTEINS;
MONOLITHIC ENZYMATIC MICROREACTOR;
MULTIDIMENSIONAL LIQUID CHROMATOGRAPHY;
PHASE LIQUIDS;
PROTEIN DIGESTION;
PROTEIN SURFACE;
PROTEOME;
PROTEOMIC ANALYSIS;
TOPDOWN;
TWO-DIMENSIONAL SEPARATIONS;
TWO-STEP PROCEDURE;
VINYL GROUP;
ACRYLIC MONOMERS;
AMIDES;
AMINES;
BODY FLUIDS;
CHROMATOGRAPHIC ANALYSIS;
DESORPTION;
ENZYMES;
FUSED SILICA;
INDUCTIVELY COUPLED PLASMA;
LIQUIDS;
LIVER;
MASS SPECTROMETERS;
MASS SPECTROMETRY;
NEGATIVE IONS;
PHOTORESISTS;
SEARCH ENGINES;
SILICA;
TWO DIMENSIONAL;
LIQUID CHROMATOGRAPHY;
ACRYLAMIDE;
AMMONIUM SULFATE;
BOVINE SERUM ALBUMIN;
LIVER EXTRACT;
MYOGLOBIN;
N,N' METHYLENEBISACRYLAMIDE;
NANOPARTICLE;
POLYACRYLIC ACID;
SILICON DIOXIDE;
ANION EXCHANGE CHROMATOGRAPHY;
ARTICLE;
CONTROLLED STUDY;
ENZYME IMMOBILIZATION;
ENZYME REACTOR;
HUMAN;
HUMAN TISSUE;
LIQUID CHROMATOGRAPHY;
MATRIX ASSISTED LASER DESORPTION IONIZATION TIME OF FLIGHT MASS SPECTROMETRY;
NANOENCAPSULATION;
NUCLEOTIDE SEQUENCE;
POLYMERIZATION;
PRIORITY JOURNAL;
PROTEIN ANALYSIS;
PROTEIN DEGRADATION;
PROTEOMICS;
REVERSED PHASE LIQUID CHROMATOGRAPHY;
ACRYLAMIDES;
ANIMALS;
CATTLE;
CHROMATOGRAPHY, LIQUID;
ENZYMES, IMMOBILIZED;
ETHYLENEDIAMINES;
HUMANS;
LIVER;
MYOGLOBIN;
NANOPARTICLES;
PROTEINS;
SERUM ALBUMIN, BOVINE;
SILICON DIOXIDE;
SPECTROMETRY, MASS, MATRIX-ASSISTED LASER DESORPTION-IONIZATION;
BOVINAE;
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EID: 70349759691
PISSN: 00219673
EISSN: None
Source Type: Journal
DOI: 10.1016/j.chroma.2009.05.003 Document Type: Article |
Times cited : (27)
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References (44)
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