-
1
-
-
34249889900
-
Mechanisms of disease: Genetic predictors of response to treatment in brain tumors
-
DOI 10.1038/ncponc0820, PII NCPONC0820
-
Collins VP (2007) Mechanisms of disease: Genetic predictors of response to treatment in brain tumors. Nat Clin Prac Oncol 4:362-374. (Pubitemid 46864310)
-
(2007)
Nature Clinical Practice Oncology
, vol.4
, Issue.6
, pp. 362-374
-
-
Collins, V.P.1
-
2
-
-
44949247296
-
Adjuvant treatment of anaplastic oligodendrogliomas and oligoastrocytomas
-
DOI 10.1002/14651858.CD007104
-
Quon H, Abdulkarim B (2008) Adjuvant treatment of anaplastic oligodendrogliomas and oligoastrocytomas. Cochrane Database Syst Rev (2):CD007104. (Pubitemid 351807223)
-
(2008)
Cochrane Database of Systematic Reviews
, Issue.2
-
-
Quon, H.1
Abdulkarim, B.2
-
3
-
-
0032494479
-
Specific genetic predictors of chemotherapeutic response and survival in patients with anaplastic oligodendrogliomas
-
Cairncross JG, et al. (1998) Specific genetic predictors of chemotherapeutic response and survival in patients with anaplastic oligodendrogliomas. J Natl Cancer Inst 90:1473-1479.
-
(1998)
J Natl Cancer Inst
, vol.90
, pp. 1473-1479
-
-
Cairncross, J.G.1
-
4
-
-
33751384307
-
Glioma therapy in adults
-
Norden AD, Wen PY (2006) Glioma therapy in adults. Neurologist 12:279-292.
-
(2006)
Neurologist
, vol.12
, pp. 279-292
-
-
Norden, A.D.1
Wen, P.Y.2
-
5
-
-
1842471336
-
Signaling through the epidermal growth factor receptor during the development of malignancy
-
DOI 10.1016/j.pharmthera.2004.01.002, PII S0163725804000208
-
Grandis JR, Sok JC (2004) Signaling through the epidermal growth factor receptor during the development of malignancy. Pharmacol Ther 102:37-46. (Pubitemid 38429984)
-
(2004)
Pharmacology and Therapeutics
, vol.102
, Issue.1
, pp. 37-46
-
-
Grandis, J.R.1
Sok, J.C.2
-
6
-
-
3242720345
-
Cetuximab monotherapy and cetuximab plus irinotecan in irinotecan- Refractory metastatic colorectal cancer
-
DOI 10.1056/NEJMoa033025
-
Cunningham D, et al. (2004) Cetuximab monotherapy and cetuximab plus irinotecan in irinotecan-refractory metastatic colorectal cancer. N Engl J Med 351:337-345. (Pubitemid 38944402)
-
(2004)
New England Journal of Medicine
, vol.351
, Issue.4
, pp. 337-345
-
-
Cunningham, D.1
Humblet, Y.2
Siena, S.3
Khayat, D.4
Bleiberg, H.5
Santoro, A.6
Bets, D.7
Mueser, M.8
Harstrick, A.9
Verslype, C.10
Chau, I.11
Van Cutsem, E.12
-
7
-
-
1842500007
-
Phase II trial of gefitinib in recurrent glioblastoma
-
Rich JN, et al. (2004) Phase II trial of gefitinib in recurrent glioblastoma. J Clin Oncol 22:133-142.
-
(2004)
J Clin Oncol
, vol.22
, pp. 133-142
-
-
Rich, J.N.1
-
8
-
-
65949101643
-
Phase II trial of preirradiation and concurrent temozolomide in patients with newly diagnosed anaplastic oligodendrogliomas and mixed anaplastic oligoastrocytomas: RTOG BR0131
-
Vogelbaum MA, et al. (2009) Phase II trial of preirradiation and concurrent temozolomide in patients with newly diagnosed anaplastic oligodendrogliomas and mixed anaplastic oligoastrocytomas: RTOG BR0131. Neuro Oncol 11:167-175.
-
(2009)
Neuro Oncol
, vol.11
, pp. 167-175
-
-
Vogelbaum, M.A.1
-
9
-
-
34250877865
-
Genetic pathways to primary and secondary glioblastoma
-
DOI 10.2353/ajpath.2007.070011
-
Ohgaki H, Kleihues P (2007) Genetic pathways to primary and secondary glioblastoma. Am J Pathol 170:1445-1453. (Pubitemid 47339290)
-
(2007)
American Journal of Pathology
, vol.170
, Issue.5
, pp. 1445-1453
-
-
Ohgaki, H.1
Kleihues, P.2
-
10
-
-
54549108740
-
Comprehensive genomic characterization defines human glioblastoma genes and core pathways
-
The Cancer Genome Atlas Research Network
-
The Cancer Genome Atlas Research Network (2008) Comprehensive genomic characterization defines human glioblastoma genes and core pathways. Nature 455:1061-1068.
-
(2008)
Nature
, vol.455
, pp. 1061-1068
-
-
-
11
-
-
34547474942
-
Insulin-like growth factor binding protein 2 promotes glioma development and progression
-
DOI 10.1073/pnas.0703145104
-
Dunlap SM, et al. (2007) Insulin-like growth factor binding protein 2 promotes glioma development and progression. Proc Natl Acad Sci USA 104:11736-11741. (Pubitemid 47175082)
-
(2007)
Proceedings of the National Academy of Sciences of the United States of America
, vol.104
, Issue.28
, pp. 11736-11741
-
-
Dunlap, S.M.1
Celestino, J.2
Wang, H.3
Jiang, R.4
Holland, E.C.5
Fuller, G.N.6
Zhang, W.7
-
12
-
-
0345240919
-
Reactivation of insulin-like growth factor binding protein 2 expression in glioblastoma multiforme: A revelation by parallel gene expression profiling
-
Fuller GN, et al. (1999) Reactivation of insulin-like growth factor binding protein 2 expression in glioblastoma multiforme: A revelation by parallel gene expression profiling. Cancer Res 59:4228-4232.
-
(1999)
Cancer Res
, vol.59
, pp. 4228-4232
-
-
Fuller, G.N.1
-
13
-
-
0034544537
-
Identification of differentially expressed genes in human gliomas by DNA microarray and tissue chip techniques
-
Sallinen SL, et al. (2000) Identification of differentially expressed genes in human gliomas by DNA microarray and tissue chip techniques. Cancer Res 60:6617-6622.
-
(2000)
Cancer Res
, vol.60
, pp. 6617-6622
-
-
Sallinen, S.L.1
-
14
-
-
34248363956
-
Insulin growth factor-binding protein 2 is a candidate biomarker for PTEN status and PI3K/Akt pathway activation in glioblastoma and prostate cancer
-
DOI 10.1073/pnas.0609139104
-
Mehrian-Shai R, et al. (2007) Insulin growth factor-binding protein 2 is a candidate biomarker for PTEN status and PI3K/AKT pathway activation in glioblastoma and prostate cancer. Proc Natl Acad Sci USA 104:5563-5568. (Pubitemid 47175720)
-
(2007)
Proceedings of the National Academy of Sciences of the United States of America
, vol.104
, Issue.13
, pp. 5563-5568
-
-
Mehrian-Shai, R.1
Chen, C.D.2
Shi, T.3
Horvath, S.4
Nelson, S.F.5
Reichardt, J.K.V.6
Sawyers, C.L.7
-
16
-
-
0034064361
-
The Ink4a/arf locus in murine tumorigenesis
-
Serrano M (2000) The Ink4a/arf locus in murine tumorigenesis. Carcinogenesis 21:865-869.
-
(2000)
Carcinogenesis
, vol.21
, pp. 865-869
-
-
Serrano, M.1
-
17
-
-
34648834721
-
Loss of Arf causes tumor progression of PDGFB-induced oligodendroglioma
-
DOI 10.1038/sj.onc.1210455, PII 1210455
-
Tchougounova E, et al. (2007) Loss of Arf causes tumor progression of PDGFB-induced oligodendroglioma. Oncogene 26:6289-6296. (Pubitemid 47462106)
-
(2007)
Oncogene
, vol.26
, Issue.43
, pp. 6289-6296
-
-
Tchougounova, E.1
Kastemar, M.2
Brasater, D.3
Holland, E.C.4
Westermark, B.5
Uhrbom, L.6
-
18
-
-
0036791177
-
Ink4a-Arf loss cooperates with kras activation in astrocytes and neural progenitors to generate glioblastomas of various morphologies depending on activated akt
-
Uhrbom L, et al. (2002) Ink4a-Arf loss cooperates with kras activation in astrocytes and neural progenitors to generate glioblastomas of various morphologies depending on activated akt. Cancer Res 62:5551-5558.
-
(2002)
Cancer Res
, vol.62
, pp. 5551-5558
-
-
Uhrbom, L.1
-
19
-
-
0042307386
-
Use of avian retroviral vectors to introduce transcriptional regulators into mammalian cells for analyses of tumor maintenance
-
DOI 10.1073/pnas.1133333100
-
Pao W, Klimstra DS, Fisher GH, Varmus HE (2003) Use of avian retroviral vectors to introduce transcriptional regulators into mammalian cells for analyses of tumor maintenance. Proc Natl Acad Sci USA 100:8764-8769. (Pubitemid 36899173)
-
(2003)
Proceedings of the National Academy of Sciences of the United States of America
, vol.100
, Issue.15
, pp. 8764-8769
-
-
Pao, W.1
Klimstra, D.S.2
Fisher, G.H.3
Varmus, H.E.4
-
20
-
-
1842533011
-
Elevated Serum Insulin-Like Growth Factor Binding Protein-2 as a Prognostic Marker in Patients with Ovarian Cancer
-
DOI 10.1158/1078-0432.CCR-0672-2
-
Baron-Hay S, Boyle F, Ferrier A, Scott C (2004) Elevated serum insulin-like growth factor binding protein-2 as a prognostic marker in patients with ovarian cancer. Clin Cancer Res 10:1796-1806. (Pubitemid 38435571)
-
(2004)
Clinical Cancer Research
, vol.10
, Issue.5
, pp. 1796-1806
-
-
Baron-Hay, S.1
Boyle, F.2
Ferrier, A.3
Scott, C.4
-
21
-
-
0027413596
-
Elevated levels of insulin-like growth factor-binding protein-2 in the serum of prostate cancer patients
-
DOI 10.1210/jc.76.4.1031
-
Cohen P, et al. (1993) Elevated levels of insulin-like growth factor-binding protein-2 in the serum of prostate cancer patients. J Clin Endocrinol Metab 76:1031-1035. (Pubitemid 23110857)
-
(1993)
Journal of Clinical Endocrinology and Metabolism
, vol.76
, Issue.4
, pp. 1031-1035
-
-
Cohen, P.1
Peehl, D.M.2
Stamey, T.A.3
Wilson, K.F.4
Clemmons, D.R.5
Rosenfeld, R.G.6
-
22
-
-
17144377116
-
Insulin-like growth factor binding protein 2: An androgen-dependent predictor of prostate cancer survival
-
DOI 10.1016/j.eururo.2004.12.015
-
Inman BA, et al. (2005) Insulin-like growth factor binding protein 2: An androgen-dependent predictor of prostate cancer survival. Eur Urol 47:695-702. (Pubitemid 40521924)
-
(2005)
European Urology
, vol.47
, Issue.5
, pp. 695-702
-
-
Inman, B.A.1
Harel, F.2
Audet, J.-F.3
Meyer, F.4
Douville, P.5
Fradet, Y.6
Lacombe, L.7
-
23
-
-
18844387869
-
Insulin-like growth factor binding protein-2 at diagnosis of childhood acute lymphoblastic leukemia and the prediction of relapse risk
-
DOI 10.1210/jc.2004-0461
-
Vorwerk P, et al. (2005) Insulin-like growth factor binding protein-2 at diagnosis of childhood acute lymphoblastic leukemia and the prediction of relapse risk. J Clin Endocrinol Metab 90:3022-3027. (Pubitemid 40686359)
-
(2005)
Journal of Clinical Endocrinology and Metabolism
, vol.90
, Issue.5
, pp. 3022-3027
-
-
Vorwerk, P.1
Mohnike, K.2
Wex, H.3
Rohl, F.-W.4
Zimmermann, M.5
Blum, W.F.6
Mittler, U.7
-
24
-
-
34547154736
-
Analysis of signaling pathways in 90 cancer cell lines by protein lysate array
-
Mendes KN, et al. (2007) Analysis of signaling pathways in 90 cancer cell lines by protein lysate array. J Proteome Res 6:2753-2767.
-
(2007)
J Proteome Res
, vol.6
, pp. 2753-2767
-
-
Mendes, K.N.1
-
25
-
-
0035425048
-
PDGF autocrine stimulation dedifferentiates cultured astrocytes and induces oligodendrogliomas from and oligoastrocytomas neural progenitors and astrocytes in vivo
-
DOI 10.1101/gad.903001
-
Dai C, et al. (2001) PDGF autocrine stimulation dedifferentiates cultured astrocytes and induces oligodendrogliomas and oligoastrocytomas from neural progenitors and astrocytes in vivo. Genes Dev 15:1913-1925. (Pubitemid 32738621)
-
(2001)
Genes and Development
, vol.15
, Issue.15
, pp. 1913-1925
-
-
Dai, C.1
Celestino, J.C.2
Okada, Y.3
Louis, D.N.4
Fuller, G.N.5
Holland, E.C.6
-
26
-
-
0043092322
-
Insulin-like growth factor binding protein 2 enhances glioblastoma invasion by activating invasion-enhancing genes
-
Wang H, et al. (2003) Insulin-like growth factor binding protein 2 enhances glioblastoma invasion by activating invasion-enhancing genes. Cancer Res 63:4315-4321. (Pubitemid 36950996)
-
(2003)
Cancer Research
, vol.63
, Issue.15
, pp. 4315-4321
-
-
Wang, H.1
Wang, H.2
Shen, W.3
Huang, H.4
Hu, L.5
Ramdas, L.6
Zhou, Y.-H.7
Liao, W.S.-L.8
Fuller, G.N.9
Zhang, W.10
-
27
-
-
0031047550
-
Point mutations can inactivate in vitro and in vivo activities of p16(INK4a)/CDKN2A in human glioma
-
Arap W, Knudsen ES, Wang JY, Cavenee WK, Huang HJ (1997) Point mutations can inactivate in vitro and in vivo activities of p16(Ink4a)/cdkn2a in human glioma. Oncogene 14:603-609. (Pubitemid 27090963)
-
(1997)
Oncogene
, vol.14
, Issue.5
, pp. 603-609
-
-
Arap, W.1
Knudsen, E.S.2
Wang, J.Y.J.3
Cavenee, W.K.4
Huang, H.-J.S.5
-
28
-
-
22144489899
-
Ink4a/arf: A multifunctional tumor suppressor locus
-
Sharpless NE (2005) Ink4a/arf: A multifunctional tumor suppressor locus. Mutat Res 576:22-38.
-
(2005)
Mutat Res
, vol.576
, pp. 22-38
-
-
Sharpless, N.E.1
-
29
-
-
0032418416
-
A constitutively active epidermal growth factor receptor cooperates with disruption of G1 cell-cycle arrest pathways to induce glioma-like lesions in mice
-
Holland EC, Hively WP, DePinho RA, Varmus HE (1998) A constitutively active epidermal growth factor receptor cooperates with disruption of G1 cell-cycle arrest pathways to induce glioma-like lesions in mice. Genes Dev 12:3675-3685.
-
(1998)
Genes Dev
, vol.12
, pp. 3675-3685
-
-
Holland, E.C.1
Hively, W.P.2
DePinho, R.A.3
Varmus, H.E.4
-
30
-
-
0029993450
-
Role of the INK4a locus in tumor suppression and cell mortality
-
DOI 10.1016/S0092-8674(00)81079-X
-
Serrano M, et al. (1996) Role of the ink4a locus in tumor suppression and cell mortality. Cell 85:27-37. (Pubitemid 26116804)
-
(1996)
Cell
, vol.85
, Issue.1
, pp. 27-37
-
-
Serrano, M.1
Lee, H.-W.2
Chin, L.3
Cordon-Cardo, C.4
Beach, D.5
Depinho, R.A.6
-
31
-
-
0037057316
-
Mdm-2 binding and taf(II)31 recruitment is regulated by hydrogen bond disruption between the p53 residues thr18 and asp21
-
Jabbur JR, et al. (2002) Mdm-2 binding and taf(II)31 recruitment is regulated by hydrogen bond disruption between the p53 residues thr18 and asp21. Oncogene 21:7100-7113.
-
(2002)
Oncogene
, vol.21
, pp. 7100-7113
-
-
Jabbur, J.R.1
|