Comparison of three doses of leuprolide acetate in the treatment of central precocious puberty: Preliminary results

Clinical Endocrinology

Volumn 71, Issue 5, 2009, Pages 686-690

  Mericq, Verónica ^a   Lammoglia, Juan Javier ^a   Unanue, Nancy ^a   Villaroel, Claudio ^a   Hernández, María Isabel ^a   Ávila, Alejandra ^a   Iñiguez, Germán ^a   Klein, Karen Oerter ^b  

^a UNIVERSITY OF CHILE   (Chile)

^b UNIVERSITY OF CALIFORNIA SAN DIEGO   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

FOLLITROPIN; GONADORELIN; LEUPRORELIN; LUTEINIZING HORMONE; SEX HORMONE;

ARTICLE; BODY HEIGHT; BONE AGE; CHILD; CHILD GROWTH; CLINICAL ARTICLE; CONTROLLED STUDY; DRUG DOSE COMPARISON; DRUG EFFICACY; DRUG TOLERABILITY; FEMALE; GONADOTROPIN RELEASE; HORMONE DETERMINATION; HUMAN; INJECTION SITE ERYTHEMA; INJECTION SITE PAIN; INJECTION SITE REACTION; INJECTION SITE SWELLING; INJECTION SITE TENDERNESS; INJECTION SITE WARMTH; PRECOCIOUS PUBERTY; PRESCHOOL CHILD; PRIORITY JOURNAL; SCHOOL CHILD;

AGE DETERMINATION BY SKELETON; CHILD; FEMALE; GONADAL STEROID HORMONES; HUMANS; LEUPROLIDE; PUBERTY, PRECOCIOUS; TREATMENT OUTCOME;

EID: 70349705865     PISSN: 03000664     EISSN: 13652265     Source Type: Journal    
DOI: 10.1111/j.1365-2265.2009.03584.x     Document Type: Article

References (16)

1. Weiss, J., Diedrich, K. Ludwig, M. (2002) Gonadotropin-releasing hormone antagonists: pharmacology and clinical use in women. Treat Endocrinology, 1 (5 281 291.
2. Klein, K.O. (1999) Precocious puberty: who has it? Who should be treated? Journal of Clinical Endocrinology and Metabolism, 84 (2 411 414.
3. Badaru, A., Wilson, D., Bachrach, L. et al. (2006) Sequential comparisons of one-month and three-month depot leuprolide regimens in central precocious puberty. Journal of Clinical Endocrinology and Metabolism, 91 (5 1862 1867.
4. Mericq, G.M.V., Youlton, R. Willshaw, M. (2006) Effectiveness of Leuprolide acetate therapy every three months in central precocious puberty. Revista Medica de Chile, 134 (7 821 826.
5. Carel, J., Lahlou, N., Jaramillo, O. et al. (2002) Treatment of central precocious puberty by subcutaneous injections of leuprorelin 3-month depot (11.25 mg). Journal of Clinical Endocrinology and Metabolism, 87 (9 4111 4116.
6. Tanaka, T., Hibi, I., Kato, K. et al. (1991) A dose finding study of a super long-acting luteinizing hormone-releasing hormone analog (leuprolide acetate depot, TAP-144-SR) in the treatment of central precocious puberty. The TAP-144-SR CPP Study Group. Endocrinologia Japonica, 38 (4 369 376.
7. Neely, E., Hintz, R., Wilson, D. et al. (1995) Normal ranges for immunochemiluminometric gonadotropin assays. Journal of Pediatrics, 127 (1 40 46.
8. Griffin, I.J., Cole, T.J., Duncan, K.A. et al. (1995) Pelvic ultrasound measurements in normal girls. Acta Paediatrica, 84 (5 536 543.
9. Buzi, F., Pilotta, A., Dordoni, D. et al. (1998) Pelvic ultrasonography in normal girls and in girls with pubertal precocity. Acta Paediatrica 87, 1138 1145.
10. Badouraki, M., Christoforidis, A., Economou, I. et al. (2008) Sonographic assessment of uterine and ovarian development in normal girls aged 1 to 12 years. Journal of Clinical Ultrasound, 36 (9 539 544.
11. Klein, K.O., Baron, J., Colli, M. et al. (1994) Estrogen levels in childhood determined by an ultrasensitive recombinant cell bioassay. Journal of Clinical Investigation, 94 (6 2475 2480.
12. Lawson, M. Cohen, N. (1999) A single sample subcutaneous luteinizing hormone (LH)-releasing hormone (LHRH) stimulation test for monitoring LH suppression in children with central precocious puberty receiving LHRH agonists. Journal of Clinical Endocrinology and Metabolism, 84 (12 4536 4540.
13. Lanes, R., Soros, A. Jakubowicz, S. (2004) Accelerated versus slowly progressive forms of puberty in girls with precocious and early puberty. Gonadotropin suppressive effect and final height obtained with two different analogs. Journal of Pediatric Endocrinology and Metabolism, 17 (5 759 766.
14. Antoniazzi, F., Cisternino, M., Nizzoli, G. et al. (1994) Final height in girls with central precocious puberty: comparison of two different luteinizing hormone-releasing hormone agonist treatments. Acta Paediatrica, 83 (10 1052 1056.
15. Kunz, G., Sherman, T.I. Klein, K.O. (2007) LH and Estradiol suppression and growth in girls with central precocious puberty: is more suppression better?. Journal of Pediatric Endocrinology and Metabolism, 20, 1189 1198.
16. Isaac, H., Patel, L., Meyer, S. et al. (2007) Efficacy of a monthly compared to 3-monthly depot GnRH analogue (goserelin) in the treatment of children with central precocious puberty. Hormone Research, 68 (4 157 163.