Enhancement of toxin- and virus-neutralizing capacity of single-domain antibody fragments by N-glycosylation

Applied Microbiology and Biotechnology

Volumn 84, Issue 6, 2009, Pages 1087-1094

  Harmsen, M M ^a   Van Solt, C B ^a   Fijten, H P D ^a  

^a WAGENINGEN UNIVERSITY   (Netherlands)

Author keywords

N glycosylation; Nanobody; Neutralization; Recombinant antibody; Yeast

Indexed keywords

ANTIBODY FRAGMENT; DEGLYCOSYLATION; FOOT-AND-MOUTH DISEASE VIRUS; FUSION PROTEINS; GLYCOSYLATED; N-GLYCOSYLATION; N-GLYCOSYLATION SITES; NANOBODY; NEUTRALIZATION; RECOMBINANT ANTIBODY; SACCHAROMYCES CEREVISIAE; SINGLE DOMAINS; SMALL SIZE;

ANTIBODIES; ESCHERICHIA COLI; GLYCOSYLATION; TOXIC MATERIALS; YEAST;

ESTERIFICATION;

BACTERIAL TOXIN; NEUTRALIZING ANTIBODY; PEPTIDE FRAGMENT; TOXIN ANTIBODY;

ANTIBODY; BACTERIUM; BIOCHEMISTRY; NEUTRALIZATION; RECOMBINATION; SIZE; TOXIN; VIRUS; YEAST;

ANIMAL CELL; ANTIGEN BINDING; ANTIGEN SPECIFICITY; ARTICLE; CONTROLLED STUDY; DEGLYCOSYLATION; ESCHERICHIA COLI; FOOT AND MOUTH DISEASE VIRUS; MOLECULAR WEIGHT; NONHUMAN; NUCLEOTIDE SEQUENCE; PROTEIN DOMAIN; PROTEIN GLYCOSYLATION; SACCHAROMYCES CEREVISIAE; VIRUS NEUTRALIZATION;

AMINO ACID SEQUENCE; ANIMALS; ANTIBODIES, NEUTRALIZING; BACTERIAL TOXINS; CAMELIDS, NEW WORLD; CERCOPITHECUS AETHIOPS; ENTEROTOXINS; EPITOPES; ESCHERICHIA COLI PROTEINS; FOOT-AND-MOUTH DISEASE; FOOT-AND-MOUTH DISEASE VIRUS; GLYCOSYLATION; IMMUNOGLOBULIN FRAGMENTS; MOLECULAR SEQUENCE DATA; RECOMBINANT FUSION PROTEINS; SACCHAROMYCES CEREVISIAE; VERO CELLS;

ESCHERICHIA COLI; FOOT-AND-MOUTH DISEASE VIRUS; SACCHAROMYCES CEREVISIAE;

EID: 70349680965     PISSN: 01757598     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00253-009-2029-1     Document Type: Article

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