In vivo alterations in skeletal muscle form and function after disuse atrophy

Medicine and Science in Sports and Exercise

Volumn 41, Issue 10, 2009, Pages 1869-1875

  Clark, Brian C ^a  

^a OHIO UNIVERSITY   (United States)

Author keywords

Bed rest; Immobilization; Limb suspension; Strength

Indexed keywords

ADIPOSE TISSUE; ARTICLE; CAST REMOVAL; HUMAN; IMMOBILIZATION; IN VIVO STUDY; MOTOR CONTROL; MUSCLE ATROPHY; MUSCLE CONTRACTION; MUSCLE FATIGUE; MUSCLE FIBER MEMBRANE RESISTANCE; MUSCLE FUNCTION; MUSCLE MASS; MUSCLE STRENGTH; MUSCLE WEAKNESS; NERVE CELL PLASTICITY; SKELETAL MUSCLE;

ADAPTATION, PHYSIOLOGICAL; BED REST; GRAVITATION; HUMANS; IMMOBILIZATION; MODELS, THEORETICAL; MUSCLE FATIGUE; MUSCLE STRENGTH; MUSCLE, SKELETAL; MUSCULAR DISORDERS, ATROPHIC;

EID: 70349680420     PISSN: 01959131     EISSN: 15300315     Source Type: Journal    
DOI: 10.1249/MSS.0b013e3181a645a6     Document Type: Article

References (59)

1. Baldwin KM, Herrick RE, McCue SA. Substrate oxidation capacity in rodent skeletal muscle: effects of exposure to zero gravity. J Appl Physiol. 1993;75(6):2466-2470
2. Berg HE, Dudley GA, Hather B, Tesch PA. Work capacity and metabolic and morphologic characteristics of the human quadriceps muscle in response to unloading. Clin Physiol. 1993;13(4): 337-347
3. Clark BC, Issac LC, Lane JL, Damron LA, Hoffman RL. Neuromuscular plasticity during and following 3-weeks of human forearm cast immobilization. J Appl Physiol. 2008;105:868-878
4. Clark BC, Fernhall B, Ploutz-Snyder LL. Adaptations in human neuromuscular function following prolonged unweighting: I. Skeletal muscle contractile properties and applied ischemia efficacy. J Appl Physiol. 2006;101(1):256-263
5. Clark BC, Hoffman RL, Russ DW. Immobilization-induced increase in fatigue resistance is not explained by changes in the muscle metaboreflex. Muscle Nerve. 2008;38(5):1466-1473
6. Clark BC, Manini TM. Sarcopenia in dynapenia. J Gerontology: Med Sci. 2008;63A(8):829-834
7. Clark BC, Manini TM, Bolanowski SJ, Ploutz-Snyder LL. Adaptations in human neuromuscular function following prolonged unweighting: II. Neurological properties and motor imagery efficacy. J Appl Physiol. 2006;101(1):264-272
8. Clark BC, Manini TM, Hoffman RL, Russ DW. Restoration of voluntary muscle strength following 3-weeks of cast immobilization is suppressed in women compared to men. Arch Phys Med Rehabil. 2009;90(1):178-180
9. Clark BC, Pierce JR, Manini TM, Ploutz-Snyder LL. Effect of prolonged unweighting of human skeletal muscle on neuromotor force control. Eur J Appl Physiol. 2007;100(1):53-62
10. Convertino VA, Doerr DF, Mathes KL, Stein SL, Buchanan P. Changes in volume, muscle compartment, and compliance of the lower extremities in man following 30 days of exposure to simulated microgravity. Aviat Space Environ Med. 1989;60(7): 653-658
11. D'Antona G, Pellegrino MA, Adami R, et al. The effect of ageing and immobilization on structure and function of human skeletal muscle fibres. J Physiol. 2003;552(Pt 2):499-511
12. de Boer MD, Maganaris CN, Seynnes OR, Rennie MJ, Narici MV. Time course of muscular, neural and tendinous adaptations to 23 day unilateral lower-limb suspension in young men. J Physiol. 2007;583(Pt 3):1079-1091
13. Deschenes MR, Giles JA, McCoy RW, Volek JS, Gomez AL, Kraemer WJ. Neural factors account for strength decrements observed after short-term muscle unloading. Am J Physiol Regul Integr Comp Physiol. 2002;282(2):R578-83
14. Duchateau J, Enoka RM. Neural adaptations with chronic activity patterns in able-bodied humans. Am J Phys Med Rehabil. 2002; 81(suppl 11):S17-27
15. Dudley GA, Duvoisin MR, Convertino VA, Buchanan P. Alterations of the in vivo torque-velocity relationship of human skeletal muscle following 30 days exposure to simulated microgravity. Aviat Space Environ Med. 1989;60(7):659-663 (Pubitemid 19174733)
16. Enoka RM. Neuromechanics of Human Movement. Champaign (IL): Human Kinetics; 2002. pp. 208-359
17. Enoka RM, Duchateau J. Muscle fatigue: what, why and how it influences muscle function. J Physiol. 2008;586(1):11-23
18. Fitts RH, Riley DR, Widrick JJ. Physiology of a microgravity environment invited review: microgravity and skeletal muscle. J Appl Physiol. 2000;89(2):823-839
19. Fuglevand AJ, Bilodeau M, Enoka RM. Short-term immobilization has a minimal effect on the strength and fatigability of a human hand muscle. J Appl Physiol. 1995;78(3):847-855
20. Gioux M, Petit J. Effects of immobilizing the cat peroneus longus muscle on the activity of its own spindles. J Appl Physiol. 1993; 75(6):2629-2635
21. Grichko VP, Heywood-Cooksey A, Kidd KR, Fitts RH. Substrate profile in rat soleus muscle fibers after hindlimb unloading and fatigue. J Appl Physiol. 2000;88(2):473-478
22. Gundersen K, Bruusgaard JC. Nuclear domains during muscle atrophy: nuclei lost or paradigm lost? J Physiol. 2008;586(Pt 11): 2675-2681
23. Hikida RS, Gollnick PD, Dudley GA, Convertino VA, Buchanan P. Structural and metabolic characteristics of human skeletal muscle following 30 days of simulated microgravity. Aviat Space Environ Med. 1989;60(7):664-670 (Pubitemid 19174734)
24. Hudson NJ, Franklin CE. Maintaining muscle mass during extended disuse: aestivating frogs as a model species. J Exp Biol. 2002;205(Pt 15):2297-2303
25. Hunter SK, Duchateau J, Enoka RM. Muscle fatigue and the mechanisms of task failure. Exerc Sport Sci Rev. 2004;32(2): 44-49
26. Jackman RW, Kandarian SC. The molecular basis of skeletal muscle atrophy. Am J Physiol Cell Physiol. 2004;287(4):C834-43
27. Jasperse JL, Woodman CR, Price EM, Hasser EM, Laughlin MH. Hindlimb unweighting decreases ecNOS gene expression and endothelium-dependent dilation in rat soleus feed arteries. J Appl Physiol. 1999;87(4):1476-1482
28. Kamiya A, Iwase S, Michikamia D, Fua Q, Mano T. Muscle sympathetic nerve activity during handgrip and post-handgrip muscle ischemia after exposure to simulated microgravity in humans. Neurosci Lett. 2000;280(1):49-52
29. Kamiya A, Michikami D, Shiozawa T, et al. Bed rest attenuates sympathetic and pressor responses to isometric exercise in anti gravity leg muscles in humans. Am J Physiol Regul Integr Comp Physiol. 2004;286(5):R844-50
30. Kandarian SC, Stevenson EJ. Molecular events in skeletal muscle during disuse atrophy. Exerc Sport Sci Rev. 2002;30(3):111-116
31. Kawakami Y, Akima H, Kubo K, et al. Changes in muscle size, architecture, and neural activation after 20 days of bed rest with and without resistance exercise. Eur J Appl Physiol. 2001;84 (1-2):7-12
32. Kitahara A, Hamaoka T, Murase N, et al. Deterioration of muscle function after 21-day forearm immobilization. Med Sci Sports Exerc. 2003;35(10):1697-1702
33. Kobayashi M, Pascual-Leone A. Transcranial magnetic stimulation in neurology. Lancet Neurol. 2003;2(3):145-156
34. LeBlanc A, Rowe R, Evans H, West S, Shackelford L, Schneider V. Muscle atrophy during long duration bed rest. Int J Sports Med. 1997;18(4 suppl):S283-5
35. LeBlanc AD, Schneider VS, Evans HJ, Pientok C, Rowe R, Spector E. Regional changes in muscle mass following 17 weeks of bed rest. J Appl Physiol. 1992;73(5):2172-2178
36. Lundbye-Jensen J, Nielsen JB. Immobilization induces changes in presynaptic control of group Ia afferents in healthy humans. J Physiol. 2008;586(Pt 17):4121-4135
37. Lynch GS. Therapies for improving muscle function in neuromuscular disorders. Exerc Sport Sci Rev. 2001;29(4):141-148
38. Manini TM, Clark BC, Nalls MA, Goodpaster BH, Ploutz-Snyder LL, Harris TB. Reduced physical activity increases intermuscular adipose tissue in healthy young adults. Am J Clin Nutr. 2007; 85(2):377-384
39. Miles MP, Clarkson PM, Bean M, Ambach K, Mulroy J, Vincent K. Muscle function at the wrist following 9 d of immobilization and suspension. Med Sci Sports Exerc. 1994;26(5): 615-623
40. Miles MP, Heil DP, Larson KR, Conant SB, Schneider SM. Prior resistance training and sex influence muscle responses to arm suspension. Med Sci Sports Exerc. 2005;37(11):1983-1989
41. Mulder ER, Kuebler WM, Gerrits KH, et al. Knee extensor fatigability after bedrest for 8 weeks with and without countermeasure. Muscle Nerve. 2007;36(6):798-806
42. Reeves ND, Maganaris CN, Ferretti G, Narici MV. Influence of 90-day simulated microgravity on human tendon mechanical properties and the effect of resistive countermeasures. J Appl Physiol. 2005;98(6):2278-2286
43. Reid J. Physiological Researches. Edinburgh (UK): Sutherland and Knox, 1848. p. 11
44. Reis J, Swayne OB, Vandermeeren Y, et al. Contribution of transcranial magnetic stimulation to the understanding of cortical mechanisms involved in motor control. J Physiol. 2008;586(2): 325-351
45. Rennie MJ. Exercise- and nutrient-controlled mechanisms involved in maintenance of the musculoskeletal mass. Biochem Soc Trans. 2007;35(Pt 5):1302-1305
46. Riley DA, Bain JL, Thompson JL, et al. Decreased thin filament density and length in human atrophic soleus muscle fibers after spaceflight. J Appl Physiol. 2000;88(2):567-572
47. Seki K, Kizuka T, Yamada H. Reduction in maximal firing rate of motoneurons after 1-week immobilization of finger muscle in human subjects. J Electromyogr Kinesiol. 2007;17(2): 113-120
48. Seki K, Taniguchi Y, Narusawa M. Alterations in contractile properties of human skeletal muscle induced by joint immobilization. J Physiol. 2001;530(Pt 3):521-532
49. Semmler JG, Kutzscher DV, Enoka RM. Gender differences in the fatigability of human skeletal muscle. J Neurophysiol. 1999; 82(6):3590-3593
50. Semmler JG, Kutzscher DV, Enoka RM. Limb immobilization alters muscle activation patterns during a fatiguing isometric contraction. Muscle Nerve. 2000;23(9):1381-1392
51. Seynnes OR, Maffiuletti NA, Maganaris CN, et al. Soleus T reflex modulation in response to spinal and tendinous adaptations to unilateral lower limb suspension in humans. Acta Physiol (Oxf). 2008;194(3):239-251
52. Shinohara M, Yoshitake Y, Kouzaki M, Fukuoka H, Fukunaga T. Strength training counteracts motor performance losses during bed rest. J Appl Physiol. 2003;95(4):1485-1492
53. Trappe S, Trappe T, Gallagher P, Harber M, Alkner B, Tesch P. Human single muscle fibre function with 84 day bed-rest and resistance exercise. J Physiol. 2004;557(Pt 2):501-513
54. Urso ML, Clarkson PM, Price TB. Immobilization effects in young and older adults. Eur J Appl Physiol. 2006;96(5):564-571
55. Veldhuizen JW, Verstappen FT, Vroemen JP, Kuipers H, Greep JM. Functional and morphological adaptations following four weeks of knee immobilization. Int J Sports Med. 1993;14(5): 283-287
56. Yasuda N, Glover EI, Phillips SM, Isfort RJ, Tarnopolsky MA. Sex-based differences in skeletal muscle function and morphology with short-term limb immobilization. J Appl Physiol. 2005;99(3): 1085-1092
57. Yoshitake Y, Kouzaki M, Fukuoka H, Fukunaga T, Shinohara M. Modulation of muscle activity and force fluctuations in the plantarflexors after bedrest depends on knee position. Muscle Nerve. 2007;35(6):745-755
58. Yue GH, Bilodeau M, Hardy PA, Enoka RM. Task-dependent effect of limb immobilization on the fatigability of the elbow flexor muscles in humans. Exp Physiol. 1997;82(3):567-592
59. Zhang P, Chen X, Fan M. Signaling mechanisms involved in disuse muscle atrophy. Med Hypotheses. 2007;69(2):310-321