Emergence of extensive-drug-resistant Pseudomonas aeruginosa in a French university hospital

European Journal of Clinical Microbiology and Infectious Diseases

Volumn 28, Issue 10, 2009, Pages 1217-1222

  Vettoretti, L ^a   Floret, N ^a   Hocquet, D ^a   Dehecq, B ^a   Plesiat P ^a   Talon, D ^a,b   Bertrand, X ^a,b  

^a UNIVERSITY HOSPITAL OF BESANÇON   (France)

^b UNIVERSITÉ DE FRANCHE COMTÉ   (France)

Author keywords

[No Author keywords available]

Indexed keywords

AMIKACIN; AZTREONAM; BETA LACTAM ANTIBIOTIC; BETA LACTAMASE; BETA LACTAMASE AMPC; CEFEPIME; CEFTAZIDIME; CIPROFLOXACIN; COLISTIN; GENTAMICIN; IMIPENEM; METALLO BETA LACTAMASE; PIPERACILLIN PLUS TAZOBACTAM; PORIN; PROTEIN OPRD; RIFAMPICIN; TICARCILLIN; TIMENTIN; TOBRAMYCIN; UNCLASSIFIED DRUG;

ANTIBIOTIC RESISTANCE; ANTIBIOTIC SENSITIVITY; ARTICLE; CONTROLLED STUDY; HUMAN; MAJOR CLINICAL STUDY; MINIMUM INHIBITORY CONCENTRATION; PRIORITY JOURNAL; PSEUDOMONAS AERUGINOSA; PSEUDOMONAS INFECTION; PULSED FIELD GEL ELECTROPHORESIS;

ANTI-BACTERIAL AGENTS; BETA-LACTAM RESISTANCE; CLUSTER ANALYSIS; COMMUNICABLE DISEASES, EMERGING; CROSS INFECTION; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG RESISTANCE, MULTIPLE, BACTERIAL; ELECTROPHORESIS, GEL, PULSED-FIELD; EPIDEMIOLOGY, MOLECULAR; FRANCE; GENOTYPE; HOSPITALS, UNIVERSITY; HUMANS; MICROBIAL SENSITIVITY TESTS; PSEUDOMONAS AERUGINOSA; PSEUDOMONAS INFECTIONS; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION;

EID: 70349675942     PISSN: 09349723     EISSN: None     Source Type: Journal    
DOI: 10.1007/s10096-009-0767-8     Document Type: Article

References (25)

1. EH Ibrahim S Ward G Sherman MH Kollef 2000 A comparative analysis of patients with early-onset vs late-onset nosocomial pneumonia in the ICU setting Chest 117 1434 1442 10.1378/chest.117.5.1434 10807834 10.1378/chest.117.5.1434 1:STN:280:DC%2BD3c3mvF2gsw%3D%3D
2. Y Carmeli N Troillet AW Karchmer MH Samore 1999 Health and economic outcomes of antibiotic resistance in Pseudomonas aeruginosa Arch Intern Med 159 1127 1132 10.1001/archinte.159.10.1127 10335691 10.1001/archinte.159.10.1127 1:STN:280:DyaK1M3ms1OhsA%3D%3D (Pubitemid 29230866)
3. DM Livermore 2002 Multiple mechanisms of antimicrobial resistance in Pseudomonas aeruginosa: our worst nightmare? Clin Infect Dis 34 634 640 10.1086/338782 11823954 10.1086/338782 1:CAS:528:DC%2BD38XitlCiur0%3D (Pubitemid 34165326)
4. N Masuda E Sakagawa S Ohya N Gotoh H Tsujimoto T Nishino 2000 Substrate specificities of MexAB-OprM, MexCD-OprJ, and MexXY-oprM efflux pumps in Pseudomonas aeruginosa Antimicrob Agents Chemother 44 3322 3327 10.1128/AAC.44.12.3322-3327.2000 11083635 10.1128/AAC.44.12.3322-3327.2000 1:CAS:528:DC%2BD3MXhs1Kit78%3D (Pubitemid 33009490)
5. PR Hsueh SP Tseng LJ Teng SW Ho 2005 Pan-drug-resistant Pseudomonas aeruginosa causing nosocomial infection at a university hospital in Taiwan Clin Microbiol Infect 11 670 673 10.1111/j.1469-0691.2005.01196.x 16008621 10.1111/j.1469-0691.2005.01196.x 1:STN:280:DC%2BD2MzlsFCnsA%3D%3D (Pubitemid 41051385)
6. H Kallel L Hergafi M Bahloul A Hakim H Dammak H Chelly, et al. 2007 Safety and efficacy of colistin compared with imipenem in the treatment of ventilator-associated pneumonia: a matched case-control study Intensive Care Med 33 1162 1167 10.1007/s00134-007-0675-2 17530220 10.1007/s00134-007-0675-2 1:CAS:528:DC%2BD1cXhtV2ltr%2FK (Pubitemid 47036903)
7. A Deplano O Denis L Poirel D Hocquet C Nonhoff B Byl, et al. 2005 Molecular characterization of an epidemic clone of panantibiotic-resistant Pseudomonas aeruginosa J Clin Microbiol 43 1198 1204 10.1128/JCM.43.3.1198-1204. 2005 15750083 10.1128/JCM.43.3.1198-1204.2005 1:CAS:528:DC%2BD2MXjtVGjs7k%3D (Pubitemid 40364938)
8. ME Falagas PK Koletsi IA Bliziotis 2006 The diversity of definitions of multidrug-resistant (MDR) and pandrug-resistant (PDR) Acinetobacter baumannii and Pseudomonas aeruginosa J Med Microbiol 55 1619 1629 10.1099/jmm.0.46747-0 17108263 10.1099/jmm.0.46747-0 1:CAS:528:DC%2BD2sXislGmtA%3D%3D (Pubitemid 44902023)
9. Balows A, Hausler WJ Jr, Herrmann KL, Isenberg HD, Shadomy HJ (1991) Manual of clinical microbiology, 5th edn. ASM Press, Washington, D.C.
10. Antibiogram Committee of the French Society for Microbiology Guidelines (2008) Available online at: http://www.sfm.asso.fr
11. C Vogne JR Aires C Bailly D Hocquet P Plésiat 2004 Role of the multidrug efflux system MexXY in the emergence of moderate resistance to aminoglycosides among Pseudomonas aeruginosa isolates from patients with cystic fibrosis Antimicrob Agents Chemother 48 1676 1680 10.1128/AAC.48.5.1676-1680. 2004 15105120 10.1128/AAC.48.5.1676-1680.2004 1:CAS:528:DC%2BD2cXjslCltb8%3D (Pubitemid 38544374)
12. D Hocquet P Berthelot M Roussel-Delvallez R Favre K Jeannot O Bajolet, et al. 2007 Pseudomonas aeruginosa may accumulate drug resistance mechanisms without losing its ability to cause bloodstream infections Antimicrob Agents Chemother 51 3531 3536 10.1128/AAC.00503-07 17682106 10.1128/AAC.00503-07 1:CAS:528:DC%2BD2sXhtFGhtbvI (Pubitemid 47519340)
13. D Hocquet X Bertrand T Köhler D Talon P Plésiat 2003 Genetic and phenotypic variations of a resistant Pseudomonas aeruginosa epidemic clone Antimicrob Agents Chemother 47 1887 1894 10.1128/AAC.47.6.1887-1894.2003 12760863 10.1128/AAC.47.6.1887-1894.2003 1:CAS:528:DC%2BD3sXktlymtLk%3D (Pubitemid 36637810)
14. J-L Dumas C van Delden K Perron T Köhler 2006 Analysis of antibiotic resistance gene expression in Pseudomonas aeruginosa by quantitative real-time-PCR FEMS Microbiol Lett 254 217 225 16445748 1:CAS:528: DC%2BD28XhsFWku7Y%3D
15. D Hocquet P Nordmann F El Garch L Cabanne P Plésiat 2006 Involvement of the MexXY-OprM efflux system in emergence of cefepime resistance in clinical strains of Pseudomonas aeruginosa Antimicrob Agents Chemother 50 1347 1351 10.1128/AAC.50.4.1347-1351.2006 16569851 10.1128/AAC.50.4.1347-1351. 2006 1:CAS:528:DC%2BD28XjvFOrsrc%3D
16. X Bertrand P Bailly G Blasco P Balvay A Boillot D Talon 2000 Large outbreak in a surgical intensive care unit of colonization or infection with Pseudomonas aeruginosa that overexpressed an active efflux pump Clin Infect Dis 31 E9 E14 10.1086/318117 11049805 10.1086/318117 1:STN:280: DC%2BD3M7htValuw%3D%3D
17. FC Tenover RD Arbeit RV Goering PA Mickelsen BE Murray DH Persing, et al. 1995 Interpreting chromosomal DNA restriction patterns produced by pulsed-field gel electrophoresis: criteria for bacterial strain typing J Clin Microbiol 33 2233 2239 7494007 1:CAS:528:DyaK2MXoslSisLc%3D
18. S Corvec L Poirel E Espaze C Giraudeau H Drugeon P Nordmann 2008 Long-term evolution of a nosocomial outbreak of Pseudomonas aeruginosa producing VIM-2 metallo-enzyme J Hosp Infect 68 73 82 10.1016/j.jhin.2007.10.016 18079018 10.1016/j.jhin.2007.10.016 1:STN:280:DC%2BD1c7lsFOltA%3D%3D
19. C Aubron L Poirel N Fortineau P Nicolas L Collet P Nordmann 2005 Nosocomial spread of Pseudomonas aeruginosa isolates expressing the metallo-beta-lactamase VIM-2 in a hematology unit of a French hospital Microb Drug Resist 11 254 259 10.1089/mdr.2005.11.254 16201928 10.1089/mdr.2005.11.254 1:CAS:528:DC%2BD2MXhtVKns77O (Pubitemid 41434170)
20. TR Walsh MA Toleman L Poirel P Nordmann 2005 Metallo-beta-lactamases: the quiet before the storm? Clin Microbiol Rev 18 306 325 10.1128/CMR.18.2.306-325. 2005 15831827 10.1128/CMR.18.2.306-325.2005 1:CAS:528:DC%2BD2MXksVymtb0%3D (Pubitemid 40548296)
21. J Quale S Bratu J Gupta D Landman 2006 Interplay of efflux system, ampC, and oprD expression in carbapenem resistance of Pseudomonas aeruginosa clinical isolates Antimicrob Agents Chemother 50 1633 1641 10.1128/AAC.50.5.1633-1641. 2006 16641429 10.1128/AAC.50.5.1633-1641.2006 1:CAS:528:DC%2BD28XksVKktro%3D
22. X Liao RE Hancock 1997 Susceptibility to beta-lactam antibiotics of Pseudomonas aeruginosa overproducing penicillin-binding protein 3 Antimicrob Agents Chemother 41 1158 1161 9145889 1:CAS:528:DyaK2sXjtVCksL0%3D
23. A Reinhardt T Köhler P Wood P Rohner JL Dumas B Ricou, et al. 2007 Development and persistence of antimicrobial resistance in Pseudomonas aeruginosa: a longitudinal observation in mechanically ventilated patients Antimicrob Agents Chemother 51 1341 1350 10.1128/AAC.01278-06 17261619 10.1128/AAC.01278-06 1:CAS:528:DC%2BD2sXktlOjtL8%3D (Pubitemid 46586815)
24. JK Johnson SM Arduino OC Stine JA Johnson AD Harris 2007 Multilocus sequence typing compared to pulsed-field gel electrophoresis for molecular typing of Pseudomonas aeruginosa J Clin Microbiol 45 3707 3712 10.1128/JCM.00560-07 17881548 10.1128/JCM.00560-07 1:CAS:528:DC%2BD2sXhsVWrtLvE (Pubitemid 350156870)
25. X Bertrand M Thouverez D Talon A Boillot G Capellier C Floriot, et al. 2001 Endemicity, molecular diversity and colonisation routes of Pseudomonas aeruginosa in intensive care units Intensive Care Med 27 1263 1268 10.1007/s001340100979 11511937 10.1007/s001340100979 1:STN:280: DC%2BD3Mvms1Kgtg%3D%3D (Pubitemid 32758922)