Deletion of the Met receptor in the collecting duct decreases renal repair following ureteral obstruction

Kidney International

Volumn 76, Issue 8, 2009, Pages 868-876

  Ma, Hong ^a   Saenko, Maryanna ^b   Opuko, Anthony ^c   Togawa, Akashi ^d   Soda, Keita ^a   Marlier, Arnaud ^a   Moeckel, Gilbert W ^e   Cantley, Lloyd G ^a   Ishibe, Shuta ^a  

^a YALE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b CARNEGIE MELLON UNIVERSITY   (United States)

^c UNIVERSITY OF KANSAS   (United States)

^d HAMAMATSU UNIVERSITY SCHOOL OF MEDICINE   (Japan)

^e YALE UNIVERSITY   (United States)

Author keywords

Fibrosis; Hgf; Met receptor; Proliferation; Repair; UUO

Indexed keywords

COLLAGEN TYPE 1; COLLAGEN TYPE 4; PLASMINOGEN ACTIVATOR INHIBITOR 1; SCATTER FACTOR RECEPTOR;

ACUTE DISEASE; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; CELL PROLIFERATION; CELL SURVIVAL; CONTROLLED STUDY; FIBROSING ALVEOLITIS; HISTOPATHOLOGY; HYDRONEPHROSIS; INTERSTITIUM; KIDNEY FIBROSIS; KIDNEY INJURY; KIDNEY TUBULE NECROSIS; MALE; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; QUANTITATIVE ANALYSIS; URETER OBSTRUCTION;

ANIMALS; APOPTOSIS; CELL PROLIFERATION; DISEASE MODELS, ANIMAL; EXTRACELLULAR MATRIX PROTEINS; FIBROSIS; HYDRONEPHROSIS; KIDNEY TUBULES, COLLECTING; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; NECROSIS; PROTO-ONCOGENE PROTEINS C-MET; RECOVERY OF FUNCTION; REGENERATION; TIME FACTORS; URETERAL OBSTRUCTION;

EID: 70349671010     PISSN: 00852538     EISSN: 15231755     Source Type: Journal    
DOI: 10.1038/ki.2009.304     Document Type: Article

References (31)

1. Ishibe S, Joly D, Zhu X et al. Phosphorylation-dependent paxillin-ERK association mediates hepatocyte growth factor-stimulated epithelial morphogenesis. Mol Cell 2003; 12: 1275-1285.
2. Ishibe S, Joly D, Liu ZX et al. Paxillin serves as an ERK-regulated scaffold for coordinating FAK and Rac activation in epithelial morphogenesis. Mol Cell 2004; 16: 257-267.
3. O'Brien LE, Zegers MM, Mostov KE. Opinion: Building epithelial architecture: insights from three-dimensional culture models. Nat Rev Mol Cell Biol 2002; 3: 531-537.
4. Ishibe S, Haydu JE, Togawa A et al. Cell confluency regulates Hgfstimulated cell morphogenesis in a {beta}-catenin dependent manner. Mol Cell Biol 2006; 26: 9232-9243.
5. Liu Y. Hepatocyte growth factor in kidney fibrosis: therapeutic potential and mechanisms of action. Am J Physiol Renal Physiol 2004; 287: F7-F16.
6. Yang J, Dai C, Liu Y. Hepatocyte growth factor suppresses renal interstitial myofibroblast activation and intercepts Smad signal transduction. Am J Pathol 2003; 163: 621-632.
7. Gao X, Mae H, Ayabe N et al. Hepatocyte growth factor gene therapy retards the progression of chronic obstructive nephropathy. Kidney Int 2002; 62: 1238-1248.
8. Dworkin LD, Gong R, Tolbert E et al. Hepatocyte growth factor ameliorates progression of interstitial fibrosis in rats with established renal injury. Kidney Int 2004; 65: 409-419.
9. Inoue T, Okada H, Kobayashi T et al. Hepatocyte growth factor counteracts transforming growth factor-beta1, through attenuation of connective tissue growth factor induction, and prevents renal fibrogenesis in 5/6 nephrectomized mice. FASEB J 2003; 17: 268-270.
10. Mizuno S, Matsumoto K, Nakamura T. Hepatocyte growth factor suppresses interstitial fibrosis in a mouse model of obstructive nephropathy. Kidney Int 2001; 59: 1304-1314.
11. Uehara Y, Minowa O, Mori C et al. Placental defect and embryonic lethality in mice lacking hepatocyte growth factor/scatter factor. Nature 1995; 373: 702-705.
12. Woolf AS, Kolatsi-Joannou M, Hardman P et al. Roles of hepatocyte growth factor/scatter factor and the met receptor in the early development of the metanephros. J Cell Biol 1995; 128: 171-184.
13. Ishibe S, Karihaloo A, Ma H et al. Met and the epidermal growth factor receptor act cooperatively to regulate final nephron number and maintain collecting duct morphology. Development 2009; 136: 337-345.
14. Huh CG, Factor VM, Sanchez A et al. Hepatocyte growth factor/c-met signaling pathway is required for efficient liver regeneration and repair. Proc Natl Acad Sci USA 2004; 101: 4477-4482.
15. Vora JP, Zimsen SM, Houghton DC et al. Evolution of metabolic and renal changes in the ZDF/Drt-fa rat model of type II diabetes. J Am Soc Nephrol 1996; 7: 113-117.
16. Rodriguez-Pena AB, Grande MT, Eleno N et al. Activation of Erk1/2 and Akt following unilateral ureteral obstruction. Kidney Int 2008; 74: 196-209.
17. Chevalier RL. Pathogenesis of renal injury in obstructive uropathy. Curr Opin Pediatr 2006; 18: 153-160.
18. Cochrane AL, Kett MM, Samuel CS et al. Renal structural and functional repair in a mouse model of reversal of ureteral obstruction. J Am Soc Nephrol 2005; 16: 3623-3630.
19. Xue F, Isaka Y, Takahara T et al. HGF-MSP chimera protects kidneys from ischemia-reperfusion injury. Biochem Biophys Res Commun 2007; 363: 451-456.
20. Miller SB, Martin DR, Kissane J et al. Insulin-like growth factor I accelerates recovery from ischemic acute tubular necrosis in the rat. Proc Natl Acad Sci USA 1992; 89: 11876-11880.
21. Kawaida K, Matsumoto K, Shimazu H et al. Hepatocyte growth factor prevents acute renal failure and accelerates renal regeneration in mice. Proc Natl Acad Sci USA 1994; 91: 4357-4361.
22. Zhang J, Yang J, Liu Y. Role of Bcl-xL induction in HGF-mediated renal epithelial cell survival after oxidant stress. Int J Clin Exp Pathol 2008; 1: 242-253.
23. Cantley LG, Barros EJ, Gandhi M et al. Regulation of mitogenesis, motogenesis, and tubulogenesis by hepatocyte growth factor in renal collecting duct cells. Am J Physiol 1994; 267: F271-F280.
24. Yang J, Liu Y. Delayed administration of hepatocyte growth factor reduces renal fibrosis in obstructive nephropathy. Am J Physiol Renal Physiol 2003; 284: F349-F357.
25. Mizuno S, Kurosawa T, Matsumoto K et al. Hepatocyte growth factor prevents renal fibrosis and dysfunction in a mouse model of chronic renal disease. J Clin Invest 1998; 101: 1827-1834.
26. Li Y, Wen X, Spataro BC et al. hepatocyte growth factor is a downstream effector that mediates the antifibrotic action of peroxisome proliferatoractivated receptor-gamma agonists. J Am Soc Nephrol 2006; 17: 54-65.
27. Liu Y, Yang J. Hepatocyte growth factor: new arsenal in the fights against renal fibrosis? Kidney Int 2006; 70: 238-240.
28. Tanaka T, Ichimaru N, Takahara S et al. In vivo gene transfer of hepatocyte growth factor to skeletal muscle prevents changes in rat kidneys after 5/6 nephrectomy. Am J Transplant 2002; 2: 828-836.
29. Mizuno S, Matsumoto K, Kurosawa T et al. Reciprocal balance of hepatocyte growth factor and transforming growth factor-beta 1 in renal fibrosis in mice. Kidney Int 2000; 57: 937-948.
30. Srichai MB, Hao C, Davis L et al. Apoptosis of the thick ascending limb results in acute kidney injury. J Am Soc Nephrol 2008; 19: 1538-1546.
31. Haroun MK, Stone JH, Nair R et al. Correlation of percentage of normal glomeruli with renal outcome in Wegener's granulomatosis. Am J Nephrol 2002; 22: 497-503.