Kinetic patterns of Candida albicans germ tube antibody in critically ill patients: Influence on mortality

Clinical and Vaccine Immunology

Volumn 16, Issue 10, 2009, Pages 1527-1528

  Zaragoza, Rafael ^a   Pemán, Javier ^b   Quindós, Guillermo ^c   Iruretagoyena, Jose R ^d   Cuétara, María S ^e   Ramírez, Paula ^b   Gómez, Maria D ^b   Camarena, Juan J ^a   Viudes, Angel ^b   Pontón, José ^c  

^a HOSPITAL UNIVERSITARIO DR PESET   (Spain)

^b HOSPITAL UNIVERSITARIO LA FE   (Spain)

^c UNIVERSITY OF THE BASQUE COUNTRY UPV EHU   (Spain)

^d HOSPITAL DE CRUCES   (Spain)

^e HOSPITAL SEVERO OCHOA   (Spain)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIFUNGAL AGENT; BIOLOGICAL MARKER; CANDIDA ALBICANS GERM TUBE ANTIBODY; FUNGUS ANTIBODY; UNCLASSIFIED DRUG;

ANTIBODY DETECTION; ANTIBODY RESPONSE; ANTIBODY TITER; ARTICLE; CANDIDA ALBICANS; CONTROLLED STUDY; CRITICALLY ILL PATIENT; HUMAN; IMMUNOASSAY; INTENSIVE CARE UNIT; INVASIVE CANDIDIASIS; MAJOR CLINICAL STUDY; MORTALITY; PREVALENCE; PRIORITY JOURNAL; TREATMENT OUTCOME;

ANTIBODIES, FUNGAL; ANTIFUNGAL AGENTS; CANDIDA ALBICANS; CANDIDIASIS; CRITICAL ILLNESS; HUMANS; KINETICS; RETROSPECTIVE STUDIES; RISK FACTORS; SPAIN;

EID: 70349664774     PISSN: 15566811     EISSN: 1556679X     Source Type: Journal    
DOI: 10.1128/CVI.00183-09     Document Type: Article

References (12)

1. Bromuro, C., V. R. La, S. Sandini, F. Urbani, C. M. Ausiello, L. Morelli, C. Fé d'ostiani, L. Romani, and A. Cassone. 1998. A 70-kilodalton recombinant heat shock protein of Candida albicans is highly immunogenic and enhances systemic murine candidiasis. Infect. Immun. 66:2154-2162.
2. Garey, K. W., M. Rege, M. P. Pai, D. E. Mingo, K. J. Suda, R. S. Turpin, and D. T. Bearden. 2006. Time to initiation of fluconazole therapy impacts mortality in patients with candidemia: a multi-institutional study. Clin. Infect. Dis. 43:25-31.
3. Gibot, S. 2005. Clinical review: role of triggering receptor expressed on myeloid cells-1 during sepsis. Crit. Care 9:485-489. (Pubitemid 41498545)
4. Iruretagoyena, J. R., P. Regulez, G. Quindós, and J. Pontón. 2000. Antibodies to Candida albicans germ tubes in two intensive care patients with invasive candidiasis. Rev. Iberoam. Micol. 17:93-96.
5. Montagnoli, C., S. Sandini, A. Bacci, L. Romani, and R. La Valle. 2004. Immunogenicity and protective effect of recombinant enolase of Candida albicans in a murine model of systemic candidiasis. Med. Mycol. 42:319-324.
6. Moragues, M. D., N. Ortiz, J. R. Iruretagoyena, J. C. Garcia-Ruiz, E. Amutio, A. Rojas, J. Mendoza, G. Quindós, and J. Pontón. 2004. Evaluation of a new commercial test (Candida albicans IFA IgG) for the serodiagnosis of invasive candidiasis. Enferm. Infecc. Microbiol. Clin. 22:83-88. (In Spanish.)
7. Morrell, M., V. J. Fraser, and M. H. Kollef. 2005. Delaying the empirical treatment of Candida bloodstream infection until positive blood culture results are obtained: a potential risk factor for hospital mortality. Antimicrob. Agents Chemother. 49:3640-3645.
8. Quindós, G., M. D. Moragues, and J. Pontón. 2004. Is there a role for antibody testing in the diagnosis of invasive candidiasis? Rev. Iberoam. Micol. 21:10-14.
9. Salesa, R., M. D. Moragues, R. Sota, J. Pemán, G. Quindós, and J. Pontón. 2001. Specific antibody response in a patient with Candida dubliniensis fungemia. Rev. Iberoam. Micol. 18:42-44.
10. Zaragoza, R., and J. Pemán. 2006. Invasive fungal infections in critically ill patients: different therapeutic options and a uniform strategy. Rev. Iberoam. Micol. 23:59-63.
11. Zaragoza, R., and J. Pemán. 2007. Diagnostic and therapeutic approach to fungal infections in critical care settings: different options but the same strategy. J. Invasive Fungal Infect. 1:50-58.
12. Zaragoza, R., J. Pemán, G. Quindós, J. R. Iruretagoyena, M. Cuetara, P. Ramirez, D. Gomez, J. Camarena, A. Viudes, and J. Pontón on behalf of the Candida albicans Germ Tube Antibody Detection in Critically Ill Patients (CAGTAUCI) Study Group. 2009. Clinical significance of Candida albicans germ tube antibody detection in critically ill patients. Clin. Microbiol. Infect. 15:592-595.