Hemodynamic effects of ephedrine, phenylephrine, and the coadministration of phenylephrine with oxytocin during spinal anesthesia for elective cesarean delivery

Anesthesiology

Volumn 111, Issue 4, 2009, Pages 753-765

  Dyer, Robert A ^a   Reed, Anthony R ^e   Van Dyk, Dominique ^e   Arcache, Michelle J ^e   Hodges, Owen ^e   Lombard, Carl J ^d   Greenwood, Jaime ^c   James, Michael F ^b  

^a UNIVERSITY OF CAPE TOWN   (South Africa)

^b UNIVERSITY OF CAPE TOWN   (South Africa)

^c NOTTINGHAM UNIVERSITY HOSPITALS NHS TRUST   (United Kingdom)

^d SOUTH AFRICAN MEDICAL RESEARCH COUNCIL   (South Africa)

^e NONE

Author keywords

[No Author keywords available]

Indexed keywords

ADRENALIN; ATROPINE; BUPIVACAINE; EPHEDRINE; FENTANYL; OXYTOCIN; PHENYLEPHRINE;

ADULT; ARTICLE; BOLUS INJECTION; BRADYCARDIA; CESAREAN SECTION; CLINICAL ARTICLE; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DOUBLE BLIND PROCEDURE; DRUG DOSE TITRATION; DRUG EFFECT; ELECTIVE SURGERY; FEMALE; HEART HEMODYNAMICS; HEART OUTPUT; HEART RATE; HEART STROKE VOLUME; HUMAN; HYPOTENSION; IMPEDANCE; MONITOR; PRIORITY JOURNAL; PULSE WAVE; RANDOMIZED CONTROLLED TRIAL; SPINAL ANESTHESIA; SYSTEMIC VASCULAR RESISTANCE; TREATMENT OUTCOME;

EID: 70349659815     PISSN: 00033022     EISSN: 15281175     Source Type: Journal    
DOI: 10.1097/ALN.0b013e3181b437e0     Document Type: Article

References (22)

1. Macarthur A, Riley ET: Obstetric anesthesia controversies: Vasopressor choice for postspinal hypotension during cesarean delivery. Int Anesthesiol Clin 2007; 45:115-132
2. Thomas DG, Robson SC, Redfern N, Hughes D, Boys RJ: Randomized trial of bolus phenylephrine or ephedrine for maintenance of arterial pressure during spinal anaesthesia for Caesarean section. Br J Anaesth 1996; 76:61-65
3. Dyer RA, Piercy JL, Reed AR, Lombard CJ, Schoeman LK, James MF: Hemodynamic changes associated with spinal anaesthesia for cesarean section in severe preeclampsia. ANESTHESIOLOGY 2008; 108:802-811
4. Langesaeter E, Rosseland LA, Stubhaug A: Continuous invasive blood pressure and cardiac output monitoring during cesarean delivery: A randomised, double-blind comparison of low dose versus high dose spinal anesthesia with intravenous phenylephrine or placebo infusion. ANESTHESIOLOGY 2008; 109:856-863
5. Benjamini Y, Hochberg Y: Controlling the false discovery rate: A practical and powerful approach to multiple testing. J R Statist Soc B 1995; 57:289-300
6. Bland JM, Altman DG: Statistical methods for assessing agreement between two methods of clinical measurement. Lancet 1986; 1:307-310
7. Ueland K, Gills RE, Hansen JM: Maternal cardiovascular dynamics. I. Cesar-ean section under subarachnoid block anesthesia. Am J Obstet Gynecol 1968; 100:42-54
8. Saravanan S, Kocarev M, Wilson RC, Watkins E, Columb MO, Lyons G: Equivalent dose of ephedrine and phenylephrine in the prevention of post-spinal hypotension in Caesarean section. Br J Anaesth 2006; 96:95-99
9. Robson SC, Boys RJ, Rodeck C, Morgan B: Maternal and fetal haemodynamic effects of spinal and extradural anaesthesia for elective caesarean section. Br J Anaesth 1992; 68:54-59
10. Introna R, Yodlowski E, Pruett J, Montano N, Porta A, Crumrine R: Sympathovagal effects of spinal anesthesia assessed by heart rate variability analysis. Anesth Analg 1995; 80:315-321
11. Kinsella SM, Tuckey JP: Perioperative bradycardia and asystole: Relationship to vasovagal syncope and the Bezold-Jarisch reflex. Br J Anaesth 2001; 86:859-868
12. Sharwood-Smith G, Drummond GB: Hypotension in obstetric spinal anaesthesia: A lesson from pre-eclampsia. Br J Anaesth 2009; 102:291-294
13. Stewart A, Fernando R, McDonald S, Hignett R, Jones T, Columb M, Abdul-Kadir R: Dose-dependent effects of phenylephrine for elective caesarean section under spinal anaesthesia: Implications for the compromised fetus? Int J Obstet Anesth 2008; 17(Suppl 1):S9
14. von Anrep G: On the part played by the suprarenals in the normal vascular reactions of the body. J Physiol 1912; 45:307-317
15. Cooper DW, Carpenter M, Mowbray P, Desira WR, Ryall DM, Kokri MS: Fetal and maternal effects of phenylephrine and ephedrine during spinal anesthesia for cesarean delivery. ANESTHESIOLOGY 2002; 97:1582-1590
16. Kurita T, Morita K, Kato S, Kikura M, Horie M, Ikeda K: Comparison of the accuracy of the lithium dilution technique with the thermodilution technique for measurement of cardiac output. Br J Anaesth 1997; 79:770-775
17. Dyer RA, James MF: Maternal hemodynamic monitoring in obstetric anesthesia. ANESTHESIOLOGY 2008; 109:765-767
18. Moshkovitz Y, Kaluski E, Milo O, Vered Z, Cotter G: Recent developments in cardiac output determination by bioimpedance: Comparison with invasive cardiac output and potential cardiovascular applications. Curr Opin Cardiol 2004; 19:229-237
19. Pinder AJ, Dresner M, Calow C, Shorten GD, O'Riordan J, Johnson R: Haemodynamic changes caused by oxytocin during caesarean section under spinal anaesthesia. Int J Obstet Anesth 2002; 11:156-159
20. Tihtonen K, Koobi T, Yli-Hankala A, Uotila J: Maternal hemodynamics during cesarean delivery assessed by whole-body impedance cardiography. Acta Obstet Gynecol Scand 2005; 84:355-361 (Pubitemid 40478184)
21. Critchley LA, Critchley JA: A meta-analysis of studies using bias and precision statistics to compare cardiac output measurement techniques. J Clin Monit Comput 1999; 15:85-91
22. Critchley LA, Peng ZY, Fok BS, James AE: The effect of peripheral resistance on impedance cardiography measurements in the anesthetized dog. Anesth Analg 2005; 100:1708-1712