Obstetric anesthesia controversies: Vasopressor choice for postspinal hypotension during cesarean delivery

International Anesthesiology Clinics

Volumn 45, Issue 1, 2007, Pages 115-132

  Macarthur, Alison ^a,c   Riley, Edward T ^b  

^a UNIVERSITY HEALTH NETWORK   (Canada)

^b STANFORD UNIVERSITY SCHOOL OF MEDICINE   (United States)

^c MOUNT SINAI HOSPITAL   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

ADRENERGIC RECEPTOR STIMULATING AGENT; ANESTHETIC AGENT; BUPIVACAINE; EPHEDRINE; FENTANYL; HYPERTENSIVE FACTOR; MEPHENTERMINE; METARAMINOL; METHOXAMINE; MORPHINE; PHENYLEPHRINE; SUFENTANIL; TERBUTALINE; TETRACAINE;

ACIDOSIS; ANESTHESIST; ARTICLE; AUSTRALIA; BLOOD PH; BRAIN PERFUSION; CANADA; CESAREAN SECTION; COLLOID; DRUG DOSE COMPARISON; EUROPE; FETUS ACIDOSIS; HUMAN; HYPOTENSION; INCIDENCE; LOCAL ANESTHESIA; MATERNAL DISEASE; MATERNAL HYPOTENSION; METABOLIC ACIDOSIS; MORBIDITY; NAUSEA; OBSTETRIC ANESTHESIA; PRIORITY JOURNAL; RECOMMENDED DRUG DOSE; RISK REDUCTION; SIDE EFFECT; SPINAL ANESTHESIA; SUBARACHNOID SPACE; UNITED STATES; UTERINE ARTERY; UTERUS BLOOD FLOW; VOMITING;

ANESTHESIA, OBSTETRICAL; ANESTHESIA, SPINAL; CESAREAN SECTION; EPHEDRINE; FEMALE; HUMANS; HYPOTENSION; PHENYLEPHRINE; PREGNANCY; VASOCONSTRICTOR AGENTS;

EID: 33846241667     PISSN: 00205907     EISSN: None     Source Type: Journal    
DOI: 10.1097/AIA.0b013e31802b8d53     Document Type: Article

References (44)

1. Skillman CA, Plessinger MA, Woods JR, et al. Effect of graded reductions in uteroplacental blood flow on the fetal lamb. Am J Physiol. 1985;149:1098-1105.
2. Carvalho B, Durbin M, Drover DR, et al. The ED50 and ED95 of intrathecal isobaric bupivacaine with opiods for cesarean delivery. Anesthesiology. 2005;103:606-612.
3. Kinsella SM, Lohmann G. Supine hypotensive syndrome. Obstet Gynecol. 1994;83:774-788.
4. Holmes F. The supine hypotensive syndrome. Anaesthesia. 1960;15:298-306.
5. Stoelting RK, Hillier SC. Sympathomimetics. In: Stoelting RK, Hillier S, eds. Pharmacology & Physiology in Anesthetic Practice. 4th ed. Philidelphia: Lippincott Williams & Wilkins; 2006:292-310.
6. Ralston DH, Shnider S, deLorimier AA. Effects of equipotent ephedrine, metaraminiol, mephenterimine and methoxamine on uterine blood flow in the pregnant ewe. Anesthesiology. 1974;40:354-370.
7. Tong C, Eisenach JC. The vascular mechanism of ephedrine's beneficial effect on uterine perfusion during pregnancy. Anesthesiology. 1992;76:792-798.
8. Ping L, Tong C, Eisenach JC. Pregnancy and ephedrine increase the release of nitric oxide in ovine uterine arteries. Anesth Analg. 1996;82:288-293.
9. Emmett RS, Cyna AM, Andrew M, et al. Techniques for preventing hypotension during spinal anaesthesia for caesarean section. Cochrane Database Syst Rev. 2002, Issue 3. Art No.: CD002251. DOI: 10.1002/14561858.CD002251.
10. Lee A, Kee WDN, Gin T. Prophylactic ephedrine prevents hypotension during spinal anesthesia for Cesarean delivery but does not improve neonatal outcome: a quantitative systematic review. Can J Anesth. 2002;49:588-599.
11. Lee A, Ngan Kee WD, Gin T. A dose-response meta-analysis of prophylactic intravenous ephedrine for the prevention of hypotension during spinal anesthesia for elective cesarean delivery. Anesth Analg. 2004;98:483-490.
12. Ueyama H, Tanigami H, Nishimura M, et al. Prophylactic intravenous administration for cesarean section during spinal anesthesia in laboring and non-laboring patients. Anesthesiology. 1992;77:A975.
13. Ngan Kee WD, Khaw KS, Lee BB, et al. A dose-response study of prophylactic ephedrine for the prevention of hypotension during spinal anesthesia for cesarean delivery. Anesth Analg. 2000;90:1390-1395.
14. Carvalho JCA, Cardoso MMSC, Capelli EL, et al. Prophylactic ephedrine during spinal anesthesia for cesarean section: bolus followed by continuous infusion in fixed doses or continuous infusion in increasing doses. Rev Bras Anesthesiol. 2000;50:425-430.
15. Loughrey JP, Walsh F, Gardiner J. Prophylactic intravenous bolus ephedrine for elective Caesarean section under spinal anaesthesia. Eur J Anaesthesiol. 2002;19:63-68.
16. Thomas DG, Robson SC, Redfern N, et al. Randomized trial of bolus phenylephrine or ephedrine for maintenance of arterial pressure during spinal anaesthesia for caesarean section. Br J Anaesth. 1996;76:61-65.
17. Ramin SM, Ramin KD, Cox K, et al. Comparison of prophylactic angiotensin II versus ephedrine infusion for prevention of maternal hypotension during spinal anesthesia. Am J Obstet Gynecol. 1994;171:734-739.
18. Cooper DW, Carpenter M, Mowbray P, et al. Fetal and maternal effects of phenylephrine and ephedrine during spinal anesthesia for cesarean delivery. Anesthesiology. 2002;97:1582-1590.
19. NganKee WD, Lau TK, Khaw KS, et al. Comparison of metaraminol and ephedrine infusions for maintaining arterial pressure during spinal anesthesia for elective cesarean section. Anesthesiology. 2001;95:307-313.
20. Riley ET. Spinal anesthesia for Caesarean delivery: keep the pressure up and don't spare the vasoconstrictors. Br J Anaesth. 2004;92:459-461.
21. MacLennan A. A template for defining a causal relationship between acute intrapartum events and cerebral palsy: international consensus statement. BMJ. 1999;319:1054-1059.
22. Sehdev HM, Stamilio DM, Macones GA, et al. Predictive factors for neonatal morbidity in neonates with an umbilical arterial cord pH less than 7.00. Am J Obst Gynecol. 1997;177:1030-1034.
23. Low JA. Intrapartum fetal asphyxia: definition, diagnosis, and classification. Am J Obst Gynecol. 1997;176:957-959.
24. Eisler G, Hjertberg R, Lagercrantz H. RCT of effect of terbutaline before elective cesarean section on postnatal respiration and glucose homeostasis. Arch Dis Child Fetal Neo. 1999;80:88-92.
25. Ngan Kee WD, Lee A. Multivariate analysis of factors associated with umbilical artery pH and standard base excess after Cesarean section under spinal anesthesia. Anaesthesia. 2003;58:125-130.
26. Yoon BH, Kim SW. The effect of labor on the normal values of umbilical blood acidbase status. Acta Obstet Gynecol Scand. 1994;73:555-561.
27. Petropoulos G, Siristatidis C, Slamalekis E, et al. Spinal and epidural versus general anesthesia for elective cesarean section at term: effect on the acid-base status of the mother and newborn. J Matern Fetal Neonatal Med. 2003;13:260-263.
28. Roberts SW, Leveno KJ, Sidawi JE, et al. Fetal acidemia associated with regional anesthesia for elective cesarean delivery. Obstet Gynecol. 1994;85:79-83.
29. Cosmi EV, Shnider SM. Obstetric anesthesia and uterine blood flow. In: Shnider SM, Levinson G, eds. Anesthesia for Obstetrics. Baltimore: Williams & Wilkins; 1987: 22-40.
30. Ramanathan S, Grant GJ. Vasopressor therapy for hypotension due to epidural anesthesia for cesarean section. Acta Anaesthesiol Scand. 1988;32:559-565.
31. Moran DH, Perillo M, LarPorta RF, et al. Phenylephrine in the prevention of hypotension following spinal anesthesia for cesarean delivery. J Clin Anesth. 1991;3:301-305.
32. Alahuta S, Rasanen J, Jouppila P, et al. Ephedrine and phenylephrine for avoiding maternal hypotension due to spinal anaesthesia for caesarean section. Int J Obstet Anesth. 1992;1:129-134.
33. Hall PA, Bennett A, Wilkes MP, et al. Spinal anaesthesia for caesarean section: comparison of infusions of phyenephrine and ephedrine. Br J Anaesth. 1994;73:471-474.
34. Pierce ET, Carr DB, Datta S. Effects of ephedrine and phenylephrine on maternal and fetal atrial natiuretic peptide levels during elective cesareand section. Acta Anaesthesiol Scand. 1994;38:48-51.
35. LaPorta RD, Arthur GR, Datta S. Phenylephrine in treating maternal hypotension due to spinkal anaesthesia for caesarean delivery: effects on neonatal catecholamine concentrations, acid base status and Apgar scores. Acta Anaesthesiol Scand. 1995;39:901-905.
36. Thomas DG, Robson SC, Redfern N, et al. Randomized trial of bolus phenylephrine or ephedrine for maintenance of arterial pressure during spinal anaesthesia for caesarean section. Br J Anaesth. 1996;76:61-65.
37. Ayorinde B, Buxzkowski P, Brown J, et al. Evaluation of preemptive intramuscular phenylephrine and ephedrine for reduction of spinal anaesthesia-induced hypotension during caesarean section. Br J Anaesth. 2001;86:372-376.
38. Lee A, Ngan Kee WD, Gin T. A quantitative, systematic review of randomized controlled trials of ephedrine versus phenylephrine for the management of hypotension during spinal anesthesia for cesarean delivery. Anesth Analg. 2002;94:920-926.
39. Ngan Kee WD, Khaw KS, Ng FF, et al. Prophylactic phenylephrine infusion for preventing hypotension during spinal anaesthesia for caesarean delivery. Anesth Analg. 2004;98:815-821.
40. Ngan Kee WD, Khaw KS, Ng FF. Comparison of phenylephrine infusion regimes for maintaining maternal blood pressure during spinal anesthesia for Caesarean section. Br J Anaesth. 2004;92:469-474.
41. Magness RR, Rosenfeld CR. Systemic and uterine response to alpha-adrenergic stimulation in pregnant and nonpregnant ewes. Am J Obstet Gynecol. 1986;155:897-904.
42. Mercier FJ, Riley ET, Fredericksonb LW, et al. Phenylephrine added to prophylactic ephedrine infusion during spinal anesthesia for elective cesarean section. Anesthesiology. 2001;95:668-674.
43. Loughrey JPR, Yao N, Datta S, et al. Hemodynamic effects of spinal anesthesia and simultaneous intravenous bolus of combined phenylephrine and ephedrine versus ephedrine for cesarean delivery. Int J Obstet Anesth. 2005;14:43-47.
44. Ngan Kee WD, Shaw KS, Ng FF. Prevention of hypotension during spinal anesthesia for cesarean delivery. Anesthesiology. 2005;103:744-750.