Epidural cooling minimizes spinal cord injury after aortic cross-clamping through induction of nitric oxide synthase

Anesthesiology

Volumn 111, Issue 4, 2009, Pages 818-825

  Morisaki, Hiroshi ^a   Ishikawa, Akiko ^b   Mori, Atsuo ^c   Kabei, Nobuyuki ^d   Yoshitake, Akihiro ^b   Suzuki, Takeshi ^b   Katori, Nobuyuki ^b   Yozu, Ryohei ^a   Takeda, Junzo ^b  

^a KEIO UNIVERSITY SCHOOL OF MEDICINE   (Japan)

^b Department of Anesthesiology ^*

^c KAWASAKI MUNICIPAL HOSPITAL   (Japan)

^d SAITAMA CARDIOVASCULAR AND RESPIRATORY CENTER   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

NITRIC OXIDE SYNTHASE;

ANIMAL EXPERIMENT; ANIMAL TISSUE; AORTA CLAMPING; ARTICLE; BLOOD FLOW; CONTROL GROUP; CONTROLLED STUDY; COOLING; EVOKED RESPONSE; IMMUNOHISTOCHEMISTRY; MALE; MOTONEURON; NONHUMAN; PERFUSION; PRIORITY JOURNAL; PROTEIN EXPRESSION; RANDOMIZATION; REPERFUSION; RISK; SCORING SYSTEM; SOMATOSENSORY CORTEX; SPINAL CORD INJURY; UPREGULATION;

EID: 70349659812     PISSN: 00033022     EISSN: 15281175     Source Type: Journal    
DOI: 10.1097/ALN.0b013e3181b764f6     Document Type: Article

References (46)

1. Crawford ES, Crawford JL, Safi HJ, Coselli JS, Hess KR, Norton HJ, Glaeser DH: Thoracoabdominal aortic aneurysms: Preoperative and intraoperative factors determining immediate and long-term results of operations in 605 patients. J Vasc Surg 1986; 3:389-404
2. Svensson LG, Crawford ES, Hess KR, Coselli JS, Safi HJ: Experience with 1509 patients undergoing thoracoabdominal aortic operations. J Vasc Surg 1993; 17:357-370
3. Ling E, Arellano R: Systematic overview of the evidence supporting the use of cerebrospinal fluid drainage in thoracoabdominal aneurysm surgery for prevention of paraplegia. ANESTHESIOLOGY 2000; 93:1115-1122
4. Acher CW, Wynn MM, Hoch JR, Popic P, Archibald J, Turnipseed WD: Combined use of cerebral spinal fluid drainage and naloxone reduces the risk of paraplegia in thoracoabdominal aneurysm repair. J Vasc Surg 1994; 19:236-244
5. Kouchoukos NT, Daily BB, Rokkas CK, Murphy SF, Bauer S, Abboud N: Hypothermic bypass and circulatory arrest for operations on the descending thoracic and thoracoabdominal aorta. Ann Thorac Surg 1995; 60:67-77
6. Rohrer MJ, Natale AM: Effect of hypothermia on the coagulation cascade. Crit Care Med 1992; 20:1402-1405
7. Kurz A, Sessler DI, Lenhardt R, The Study of Wound Infection and Temperature Group: Perioperative normothermia to reduce the incidence of surgical-wound infection and shorten hospitalization. N Engl J Med 1996; 334:1209-1215
8. Cambria RP, Davidson JK, Zannetti S, L'Italien G, Brewster DC, Gertler JP, Moncure AC, LaMuraglia GM, Abbott WM: Clinical experience with epidural cooing for spinal cord protection during thoracic and thoracoabdominal aneu-rysm repair. J Vasc Surg 1997; 25:234-243
9. Yoshitake A, Mori A, Shimizu H, Ueda T, Kabei N, Hachiya T, Okano H, Yozu R: Use of an epidural cooling catheter with a closed countercurrent lumen to protect against ischemic spinal cord injury in pigs. J Thorac Cardiovasc Surg 2007; 134:1220-1226
10. Moomiaie RMA, Ransden J, Stein J, Strugar J, Zhu QB, Kim JH, Elefteriades JA: Cooling catheter for spinal cord preservation in thoracic aortic surgery. J Cardiovasc Surg 2007; 48:103-108
11. Zhou Y, Zhao YN, Yang EB, Ling EA, Wang Y, Hassouna MM, Mack P: Induction of neuronal and inducible nitric oxide synthase in the motoneurons of spinal cord following transient abdominal aorta occlusion in rats. J Surg Res 1999; 87:185-193
12. Beattie MS: Inflammation and apoptosis: linked therapeutic targets in spinal cord injury. Trends Mol Med 2004; 10:580-583
13. Nakahara S, Yone K, Setoguchi T, Yamaura I, Arishima Y, Yoshino S, Komiya S: Changes in nitric oxide and expression of nitric oxide synthase in spinal cord after acute traumatic injury in rats. J Neurotrauma 2002; 19:1467-1474
14. Conti A, Miscusi M, Cardali S, Germanò A, Suzuki H, Cuzzocrea S, Toma-sello F: Nitric oxide in the injured spinal cord: Synthases cross-talk, oxidative stress and inflammation. Brain Res Rev 2007; 54:205-218
15. Pannu R, Singh I: Pharmacological strategies for the regulation of inducible nitric oxide synthase: Neurodegenerative versus neuroprotecive mechanisms. Neurochem Intern 2006; 49:170-182
16. Mok JM, Lyon R, Lieberman JA, Cloyd JM, Burch S: Monitoring of nerve root injury using transcranial motor-evoked potentials in a pig model. Spine 2008; 33:E465-73
17. Lips J, de Haan P, Bouma GJ, Jacobs MJ, Kalkman CJ: Delayed detection of motor pathway dysfunction after selective reduction of thoracic spinal cord blood flow in pigs. J Thorac Cardiovasc Surg 2002; 123:531-538
18. Orlin JR, Osen KK, Hovig T: Subdural compartment in pig: A morphologic study with blood and horseradish peroxidase infused subdurally. Anat Rec 2005; 230:22-37
19. Nilsson GE, Tenland T, Obert PA: A new instrument for continuous measurement of tissue blood flow by light beating spectroscopy. IEEE Trans Biomed Eng 1980; 27:12-19
20. Tarlov IM: Acute spinal cord compression paralysis. J Neurosurg 1972; 36:10-20
21. Mori A, Ueda T, Hachiya T, Kabei N, Okano H, Yozu R, Sasaki T: An epidural cooling catheter protects the spinal cord against ischemic injury in pigs. Ann Thorac Surg 2005; 80:1829-1834
22. Dumont RJ, Okonkwo DO, Verma S, Hurlbert RJ, Boulos PT, Ellegala DB, Dumont AS: Acute spinal cord injury, part I: Pathophysiologic mechanisms. Clin Neuropharmacol 2001; 24:254-264 (Pubitemid 32906712)
23. Jacobs TP, Shohami E, Baze W, Burgard E, Gunderson C, Hallenbeck JM, Feuerstein G: Deteriorating stroke model: Histopathology, edema, and eicosanoid changes following spinal cord ischemia in rabbits. Stroke 1987; 18:741-750
24. Wong DR, Coselli JS, Amerman K, Bozinovski J, Carter SA, Vaughn WK, LeMaire SA: Delayed spinal cord deficits after thoracoabdominal aortic aneurysm repair. Ann Thorac Surg 2007; 83:1345-1355
25. Strauch JT, Spielvogel D, Lauten A, Zhang N, Shiang H, Weisz D, Bodian CA, Griepp RB: Importance of extrasegmental vessels for spinal cord blood supply in a chronic porcine model. Eur J Cardio-thorac Surg 2003; 24:817-824
26. Taira Y, Marsala M: Effect of proximal arterial perfusion pressure on function, spinal cord blood flow, and histopathologic changes after increasing intervals of aortic occlusion in the rat. Stroke 1996; 27:1850-1858
27. Hayashi T, Sakurai M, Abe K, Sadahiro M, Tabayashi K, Itoyama Y: Apo-ptosis of motor neurons with induction of caspases in the spinal cord after ischemia. Stroke 1998; 29:1007-1013 (Pubitemid 28228165)
28. Jacobs TP, Kempski O, McKinley D, Dutka AJ, Hallenbeck JM, Feuerstein G: Blood flow and vascular permeability during motor dysfunction in a rabbit model of spinal cord ischemia. Stroke 1992; 23:367-373
29. Strauch JT, Lauten A, Spielvogel D, Rinke S, Zhang N, Weisz D, Bodian CA, Greipp RB: Mild hypothermia protects the spinal cord from ischemic injury in a chronic porcine model. Eur J Cardio-thorac Surg 2004; 25:708-715
30. Shine TSJ, Harrison BA, De Ruyter ML, Crook JE, Heckman M, Daube JR, Stapelfeldt WH, Cherry KJ, Gloviczki P, Bower TC, Murray MJ: Motor and somatosensory evoked potentials. Their role in predicting spinal cord ischemia in patients undergoing thoracoabdominal aortic aneurysm repair with regional lumbar epidural cooling. ANESTHESIOLOGY 2008; 108:580-587
31. Kahn RA, Stone ME, Moskowitz DM: Anesthetic consideration for descending thoracic aortic aneurysm repair. Sem Cardiothorac Vasc Anesth 2007; 11: 205-223
32. Grabitz K, Sandmann W, Stühmeier K, Mainzer B, Godehardt E, Ohre B, Hartwich U: The risk of ischemic spinal cord injury in patients undergoing graft replacement for thoracoabdominal aortic aneurysms. J Vasc Surg 1996; 23: 230-240
33. Laschinger JC, Cunningham JN, Cooper MM, Baumann FG, Spencer FC: Monitoring of somatosensory evoked potentials during surgical procedures on the thoracoabdominal aorta. I. Relationship of aortic cross-clamp duration, changes in somatosensory evoked potentials, and incidence of neurologic dysfunction. J Thorac Cardiovasc Surg 1987; 94:260-265
34. Svensson LG, Hunter SJS, Von Ritter CM, Robinson MF, Groeneveld HT, Hinder RA, Rickards ES: Cross clamping of the thoracic aorta: Influence of aortic shunts, laminectomy, papaverine, calcium channel blocker, allopurinol, and superoxide dismutase on spinal cord blood flow and paraplegia in baboons. Ann Surg 1986; 204:38-47
35. Barone GW, Joop AW, Flanagan TL, Dunn CE, Kron IL: The effect of hyperemia on spinal cord function after temporary thoracic aortic occlusion. J Vasc Surg 1988; 8:535-540
36. Steen PA, Newberg LA, Milde JH, Michenfelder JD: Nimodipine improves cerebral blood flow and neurologic recovery after complete cerebral ischemia in the dog. J Cereb Blood Flow Metab 1983; 3:38-43
37. Meyer FB, Anderson RE, Friedrich PF: MK-801 attenuates capillary bed compression and hypoperfusion following incomplete focal cerebral ischemia. J Cereb Blood Flow Metab 1990; 10:895-902
38. Papakostas JC, Matsagas MI, Toumpoulis IK, Malamou-Mitsi VD, Pappa LS, Gkrepi C, Anagnostopoulos CE, Kappas AM: Evolution of spinal cord injury in a porcine model of prolonged aortic occlusion. J Surg Res 2006; 133:159-166
39. Iadecola C, Zhang F, Xu X: Inhibition of inducible nitric oxide synthase ameliorates cerebral ischemic damage. Am J Phsyiol 1995; 268:R286-92
40. Hamada Y, Ikata T, Katoh S, Tsuchiya K, Niwa M, Tsutsumishita Y, Fukuzawa K: Roles of nitric oxide in compression injury of rat spinal cord. Free Radic Biol Med 1996; 20:1-9 (Pubitemid 26014315)
41. Kim H, Yi JW, Sung YH, Kim CJ, Kim CS, Kang JM: Delayed preconditioning effect of isoflurane on spinal cord ischemia in rats. Neurosci Lett 2008; 440:211-216
42. Hassoun HT, Kozar RA, Kone BC, Safi HJ, Moore FA: Intraischemic hypothermia differentially modulates oxidative stress proteins during mesenteric isch-emia/reperfusion. Surgery 2002; 132:369-376
43. Iadecola C: Bright and dark sides of nitric oxide in ischemic brain injury. Trends Neurosci 1997; 20:132-139
44. Bolan?os JP, Almeida A: Roles of nitric oxide in brain hypoxia-ischemia. Biochim Biophys Acta 1999; 1411:415-436
45. Zhao W, Xie W, Le W, Beers DR, He Y, Henkel JS, Simpson EP, Yen AA, Xiao Q, Appel SH: Activated microglia initiate motor neuron injury by a nitric oxide and glutamate-mediated mechanism. J Neuropathol Exp Neurol 2004; 63:964-977
46. Zhu DY, Liu SH, Sun HS, Lu YM: Expression of inducible nitric oxide synthase after focal cerebral ischemia stimulates neurogenesis in the adult rodent dentate gyrus. J Neurosci 2003; 23:223-229