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Volumn 53, Issue 9, 2009, Pages 1123-1133

Aromatic hydroxylation is a major metabolic pathway of the mycotoxin zearalenone in vitro

Author keywords

Aromatic hydroxylation; Catechols; Human liver; Microsomes; Zearalenone

Indexed keywords

CATECHOL METHYLTRANSFERASE; CYTOCHROME P450; ZEARALENONE;

EID: 70349636003     PISSN: 16134125     EISSN: 16134133     Source Type: Journal    
DOI: 10.1002/mnfr.200800584     Document Type: Article
Times cited : (47)

References (20)
  • 1
    • 8844247487 scopus 로고    scopus 로고
    • Opinion of the Scientific Panel on Contaminants in the Food Chain on a request from the Commission related to Zearalenone as undesirable substance in animal feed
    • European Food Safety Authority
    • European Food Safety Authority, Opinion of the Scientific Panel on Contaminants in the Food Chain on a request from the Commission related to Zearalenone as undesirable substance in animal feed, EFSA J. 2004, 89, 1-35.
    • (2004) EFSA J , vol.89 , pp. 1-35
  • 4
    • 0019420039 scopus 로고
    • A-Zearalenol, a major hepatic metabolite in rats of zearalenone, an estrogenic mycotoxin of Fusarium species
    • Ueno, Y., Tashiro, F. J., a-Zearalenol, a major hepatic metabolite in rats of zearalenone, an estrogenic mycotoxin of Fusarium species, Biochemistry 1981, 89, 563-571.
    • (1981) Biochemistry , vol.89 , pp. 563-571
    • Ueno, Y.1    Tashiro, F.J.2
  • 5
    • 33751251394 scopus 로고    scopus 로고
    • Review on the toxicity, occurrence, metabolism, detoxification, regulations and intake of zearalenone: An estrogenic mycotoxin
    • Zinedine, A., Soriano, J. M., Molto, J. C., Manes, J., Review on the toxicity, occurrence, metabolism, detoxification, regulations and intake of zearalenone: an estrogenic mycotoxin, Food Chem. Toxicol. 2007, 45, 1-18.
    • (2007) Food Chem. Toxicol. , vol.45 , pp. 1-18
    • Zinedine, A.1    Soriano, J.M.2    Molto, J.C.3    Manes, J.4
  • 6
    • 33846409114 scopus 로고    scopus 로고
    • Characterization of the estrogenic activities of zearalenone and zeranol in vivo and in vitro
    • Takemura, H., Shim, J.-Y., Sayama, K., Tsubura, A., et al., Characterization of the estrogenic activities of zearalenone and zeranol in vivo and in vitro, J. Steroid Biochem. Mol. Biol. 2007,103,170-177.
    • (2007) J. Steroid Biochem. Mol. Biol. , vol.103 , pp. 170-177
    • Takemura, H.1    Shim, J.-Y.2    Sayama, K.3    Tsubura, A.4
  • 7
    • 0019459657 scopus 로고
    • Comparative metabolism of zearalenone and transmission into bovine milk
    • Mirocha, C. J., Pathre, S. V., Robison, T. S., Comparative metabolism of zearalenone and transmission into bovine milk, Food Cosmet. Toxicol. 1981, 19, 25-30.
    • (1981) Food Cosmet. Toxicol. , vol.19 , pp. 25-30
    • Mirocha, C.J.1    Pathre, S.V.2    Robison, T.S.3
  • 8
    • 0020533094 scopus 로고
    • Species differences in zearalenone-reducing activity in subcellular fractions of liver from female domestic animals
    • Olsen, M., Kiessling, K.-H., Species differences in zearalenone-reducing activity in subcellular fractions of liver from female domestic animals, Acta Pharmacol. Toxicol. 1983, 52, 287-291.
    • (1983) Acta Pharmacol. Toxicol. , vol.52 , pp. 287-291
    • Olsen, M.1    Kiessling, K.-H.2
  • 9
    • 33744915539 scopus 로고    scopus 로고
    • Species differences in the hepatic biotransformation of zearalenone
    • Malekinejad, H., Maas-Bakker, R., Fink-Gremmels, J., Species differences in the hepatic biotransformation of zearalenone, Vet. J. 2006, 172, 96-102.
    • (2006) Vet. J. , vol.172 , pp. 96-102
    • Malekinejad, H.1    Maas-Bakker, R.2    Fink-Gremmels, J.3
  • 10
    • 84871086678 scopus 로고
    • National Toxicology Program, Carcinogenesis bioassay of zearalenone in F344/N rats and B6C3F1 mice. National Toxicology Program technical report no. 235, Research Triangle Park, NC
    • National Toxicology Program, Carcinogenesis bioassay of zearalenone in F344/N rats and B6C3F1 mice. National Toxicology Program technical report no. 235, 1982. Department of Health and Human Services, Research Triangle Park, NC.
    • (1982) Department of Health and Human Services
  • 11
    • 34547473752 scopus 로고    scopus 로고
    • Novel oxidative metabolites of the mycoestrogen zearalenone in vitro
    • Pfeiffer, E., Heyting, A., Metzler, M., Novel oxidative metabolites of the mycoestrogen zearalenone in vitro, Mol. Nutr. Food Res. 2007, 51, 867-871.
    • (2007) Mol. Nutr. Food Res. , vol.51 , pp. 867-871
    • Pfeiffer, E.1    Heyting, A.2    Metzler, M.3
  • 12
    • 35548956874 scopus 로고    scopus 로고
    • Stable isotope dilution analysis of the Fusarium mycotoxin zearalenone
    • Cramer, B., Bretz, M., Humpf, H.-U., Stable isotope dilution analysis of the Fusarium mycotoxin zearalenone, J. Agric. Food Chem. 2007, 55, 8353-8358.
    • (2007) J. Agric. Food Chem. , vol.55 , pp. 8353-8358
    • Cramer, B.1    Bretz, M.2    Humpf, H.-U.3
  • 14
    • 33244473463 scopus 로고    scopus 로고
    • Metabolism of curcuminoids in tissue slices and subcellular fractions from rat liver
    • Hoehle, S. I., Pfeiffer, E., Slyom, A. M., Metzler, M., Metabolism of curcuminoids in tissue slices and subcellular fractions from rat liver, J. Agric. Food Chem. 2006, 54, 756-764.
    • (2006) J. Agric. Food Chem. , vol.54 , pp. 756-764
    • Hoehle, S.I.1    Pfeiffer, E.2    Slyom, A.M.3    Metzler, M.4
  • 15
    • 0001314247 scopus 로고
    • Toxicity of chlorobenzenes in cultured rat liver slices
    • Fisher, R., Smith, P. F., Sipes, I. G., Gandolfi, A. J., et al., Toxicity of chlorobenzenes in cultured rat liver slices, In vitro Toxicol. 1990, 3, 181-194.
    • (1990) In vitro Toxicol , vol.3 , pp. 181-194
    • Fisher, R.1    Smith, P.F.2    Sipes, I.G.3    Gandolfi, A.J.4
  • 17
    • 0343279387 scopus 로고
    • Some biological and toxicological studies of various estrogen mycotoxins and phytoestrogens
    • in: McLachlan, J. A. (Ed.), Elsevier New York, Amsterdam, Oxford
    • Li, J. J., Li, S. A., Klicka, J. K., Heller, J. A., Some biological and toxicological studies of various estrogen mycotoxins and phytoestrogens. in: McLachlan, J. A. (Ed.) Estrogens in the Environment II: Influences on Development, Elsevier New York, Amsterdam, Oxford 1985, pp. 168-181.
    • (1985) Estrogens in the Environment II: Influences on Development , pp. 168-181
    • Li, J.J.1    Li, S.A.2    Klicka, J.K.3    Heller, J.A.4
  • 18
    • 33847795224 scopus 로고    scopus 로고
    • Catechol quinones of estrogens in the initiation of breast, prostate, and other human cancers. Keynote Lecture
    • Cavalieri, E., Rogan, E., Catechol quinones of estrogens in the initiation of breast, prostate, and other human cancers. Keynote Lecture, Ann. N. Y. Acad. Sci. 2006, 1089, 286-301.
    • (2006) Ann. N. Y. Acad. Sci. , vol.1089 , pp. 286-301
    • Cavalieri, E.1    Rogan, E.2
  • 19
    • 0028839564 scopus 로고
    • Genotoxicity of zearalenone, an estrogenic mycotoxin: DNA adduct formation in female mouse tissue
    • Pfohl-Leszkowicz, A., Chekir-Ghedira, L., Bacha, H., Genotoxicity of zearalenone, an estrogenic mycotoxin: DNA adduct formation in female mouse tissue, Carcinogenesis 1995,16,2315-2320.
    • (1995) Carcinogenesis , vol.16 , pp. 2315-2320
    • Pfohl-Leszkowicz, A.1    Chekir-Ghedira, L.2    Bacha, H.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.