Evaluating the performance of models for predicting the BRCA germline mutations in Han Chinese familial breast cancer patients

Breast Cancer Research and Treatment

Volumn 116, Issue 3, 2009, Pages 563-570

  Rao, Nan Yan ^a,b   Hu, Zhen ^a   Yu, Jin Ming ^a   Li, Wen Feng ^a   Zhang, Bin ^c   Su, Feng Xi ^b   Wu, Jiong ^a   Shen, Zhen Zhou ^a   Huang, Wei ^d   Shao, Zhi Ming ^a  

^a FUDAN UNIVERSITY   (China)

^b SUN YAT SEN UNIVERSITY   (China)

^c LIAONING CANCER HOSPITAL AND INSTITUTE   (China)

^d CHINESE NATIONAL HUMAN GENOME CENTER AT SHANGHAI   (China)

Author keywords

BRCA1; BRCA2; Breast cancer; Mutation; Probability model

Indexed keywords

BRCA1 PROTEIN; BRCA2 PROTEIN;

ADULT; ARTICLE; BREAST CANCER; CANCER RISK; CHINESE; COMPUTER MODEL; CONTROLLED STUDY; DIAGNOSTIC ACCURACY; DIAGNOSTIC TEST ACCURACY STUDY; FAMILIAL CANCER; FAMILY; FEMALE; GENE MUTATION; GENETIC ANALYSIS; GENETIC COUNSELING; GENETIC RISK; HIGH RISK POPULATION; HUMAN; INTERMETHOD COMPARISON; MAJOR CLINICAL STUDY; MALE; MUTATIONAL ANALYSIS; NUCLEOTIDE SEQUENCE; PREDICTIVE VALUE; PRIORITY JOURNAL; PROBABILITY; RECEIVER OPERATING CHARACTERISTIC; RISK ASSESSMENT; SENSITIVITY AND SPECIFICITY; BREAST TUMOR; COMPARATIVE STUDY; COMPUTER SIMULATION; EVALUATION; GENETIC PREDISPOSITION; GENETICS; MIDDLE AGED; MUTATION; PREDICTION AND FORECASTING; ROC CURVE; STATISTICAL MODEL; TUMOR SUPPRESSOR GENE;

ADULT; BREAST NEOPLASMS; COMPUTER SIMULATION; DNA MUTATIONAL ANALYSIS; FEMALE; GENES, BRCA1; GENES, BRCA2; GENETIC PREDISPOSITION TO DISEASE; GERM-LINE MUTATION; HUMANS; MIDDLE AGED; MODELS, STATISTICAL; PREDICTIVE VALUE OF TESTS; PROBABILITY; ROC CURVE; SENSITIVITY AND SPECIFICITY;

EID: 70349579953     PISSN: 01676806     EISSN: 15737217     Source Type: Journal    
DOI: 10.1007/s10549-008-0181-4     Document Type: Article

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