Blastic plasmacytoid dendritic cell neoplasm - A rare differential diagnosis of neoplastic skin infiltrations associated with systemic symptoms;Blastische plasmozytoide neoplasie dendritischer zellen - seltene differenzialdiagnose neoplastischer hautinfiltrate mit systemischer beteiligung

Deutsche Medizinische Wochenschrift

Volumn 134, Issue 39, 2009, Pages 1927-1930

  Loffler H ^a,b   Kosely, F ^b   Ho, A D ^b   Kramer A ^a,b  

^a GERMAN CANCER RESEARCH CENTER DKFZ   (Germany)

^b UNIVERSITY HOSPITAL HEIDELBERG   (Germany)

Author keywords

Agranular CD4 +CD56 + hematodermic; Cutaneous neoplasia; DC2 cell; Malignant histiocytosis; Plasmacytoid dendritic cell

Indexed keywords

CD4 ANTIGEN; CD56 ANTIGEN; CYTARABINE; DAUNORUBICIN; ANTINEOPLASTIC AGENT;

AGED; ARTICLE; BLASTIC PLASMACYTOID DENDRITIC CELL NEOPLASM; CANCER COMBINATION CHEMOTHERAPY; CANCER INFILTRATION; CANCER REGRESSION; CASE REPORT; CLINICAL FEATURE; DENDRITIC CELL; DIFFERENTIAL DIAGNOSIS; FEMALE; HISTOPATHOLOGY; HUMAN; INFECTION; LYMPHOMA; PANCYTOPENIA; PROGNOSIS; RASH; SKIN BIOPSY; SKIN DEFECT; SYMPTOM; ACUTE GRANULOCYTIC LEUKEMIA; BIOPSY; BONE MARROW; CLASSIFICATION; FLOW CYTOMETRY; IMMUNOHISTOCHEMISTRY; IMMUNOPHENOTYPING; PATHOLOGY; REMISSION; SKIN; SKIN TUMOR;

AGED; ANTINEOPLASTIC AGENTS; BIOPSY; BONE MARROW; DIAGNOSIS, DIFFERENTIAL; EXANTHEMA; FEMALE; FLOW CYTOMETRY; HUMANS; IMMUNOHISTOCHEMISTRY; IMMUNOPHENOTYPING; LEUKEMIA, MYELOID, ACUTE; PANCYTOPENIA; PROGNOSIS; REMISSION INDUCTION; SKIN; SKIN NEOPLASMS;

EID: 70349575216     PISSN: 00120472     EISSN: 14394413     Source Type: Journal    
DOI: 10.1055/s-0029-1237532     Document Type: Article

References (11)

1. Briere F, Bendriss-Vermare N, Delale T, et al. Origin and filiation of human plasmacytoid dendritic cells. Hum Immunol 2002; 63: 1081- 1093
2. Chaperot L, Bendriss N, Manches O, et al. Identification of a leukemic counterpart of the plasmacytoid dendritic cells. Blood 2001; 97: 3210-3217
3. Facchetti F, Jones D M., Petrella T. Blastic plasmacytoid dendritic cell neoplasm.In: Swerdlow SH, Campo E, Harris NL, et al eds (Hrsg). WHO classification of tumours of haematopoietic and lymphoid tissues. 4th ed. Lyon: International Agency for Research on Cancer, 2008: 145-147
4. Feuillard J, Jacob M C., Valensi F, et al. Clinical and biologic features of CD4(+)CD56(+) malignancies. Blood 2002; 99: 1556-1563
5. Garnache-Ottou F, Feuillard J, Saas P. Plasmacytoid dendritic cell leukaemia/lymphoma: towards a well defined entity? Br J Haematol 2007; 136: 539-548
6. Herling M, Jones D. CD4+/CD56+ hematodermic tumor: the features of an evolving entity and its relationship to dendritic cells. Am J Clin Pathol 2007; 127: 687-700
7. Hwang S T., Janik J E., Jaffe E S., Wilson W H. Mycosis fungoides and Sezary syndrome. Lancet 2008; 371: 945-957
8. Jacob M C., Chaperot L, Mossuz P, et al. CD4+ CD56+ lineage negative malignancies: a new entity developed from malignant early plasmacytoid dendritic cells. Haematologica 2003; 88: 941-955
9. Merad M, Manz M G. Dendritic cell homeostasis. Blood 2009 113 3418-3427
10. Petrella T, Bagot M, Willemze R, et al. Blastic NK-cell lymphomas (agranular CD4+CD56+ hematodermic neoplasms): a review. Am J Clin Pathol 2005; 123: 662-675
11. Reimer P, Rudiger T, Kraemer D, et al. What is CD4+CD56+ malignancy and how should it be treated? Bone Marrow Transplant 2003; 32: 637-646