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Volumn 21, Issue 8, 2009, Pages 751-759

Use of toxicity assays for enantiomeric discrimination of pharmaceutical substances

Author keywords

Enantiomeric effects; Pharmaceutical drugs; Stereoselective toxicity; Toxicity assays; Water environments

Indexed keywords

ATENOLOL; DOPA; FLUOXETINE; LEVODOPA;

EID: 70349556073     PISSN: 08990042     EISSN: 1520636X     Source Type: Journal    
DOI: 10.1002/chir.20675     Document Type: Article
Times cited : (77)

References (29)
  • 1
    • 0038544203 scopus 로고    scopus 로고
    • Ecotoxicological impact of pharmaceuticals found in treated wastewaters: Study of carbamazepine, clofibric acid and diclofenac
    • Ferrari B, Paxéus N, Lo Giudice R, Pollio A, Garric J. Ecotoxicological impact of pharmaceuticals found in treated wastewaters: study of carbamazepine, clofibric acid and diclofenac. Ecotoxicol Environ Saf 2003;55:359-370.
    • (2003) Ecotoxicol Environ Saf , vol.55 , pp. 359-370
    • Ferrari, B.1    Paxéus, N.2    Lo Giudice, R.3    Pollio, A.4    Garric, J.5
  • 2
    • 0033833186 scopus 로고    scopus 로고
    • Environmental risk assessment of antibiotics: Comparison of mecillinam, trimethoprim and ciprofloxacin
    • Halling Sorensen B, Holten Lützhoft HC, Andersen HR, Ingerslev F. Environmental risk assessment of antibiotics: comparison of mecillinam, trimethoprim and ciprofloxacin. J Antimicrob Chemother 2000;46 (suppl. 1):53-58.
    • (2000) J Antimicrob Chemother , vol.46 , Issue.SUPPL. 1 , pp. 53-58
    • Halling Sorensen, B.1    Holten Lützhoft, H.C.2    Andersen, H.R.3    Ingerslev, F.4
  • 3
    • 0033383635 scopus 로고    scopus 로고
    • Pharmaceuticals and personal care products in the environment: Agents of subtle change?
    • Daughton CG, Ternes TA. Pharmaceuticals and personal care products in the environment: agents of subtle change? Environ Health Perspect 1999;107 (suppl. 6):907-938.
    • (1999) Environ Health Perspect , vol.107 , Issue.SUPPL. 6 , pp. 907-938
    • Daughton, C.G.1    Ternes, T.A.2
  • 4
    • 14644389378 scopus 로고    scopus 로고
    • Human pharmaceuticals, hormones, and personal care product ingredients in runoff from agricultural fields irrigated with treated wastewater
    • Pedersen JA, Soliman M, Suffet IH. Human pharmaceuticals, hormones, and personal care product ingredients in runoff from agricultural fields irrigated with treated wastewater. J Agric Food Chem 2005;53:1625-1632.
    • (2005) J Agric Food Chem , vol.53 , pp. 1625-1632
    • Pedersen, J.A.1    Soliman, M.2    Suffet, I.H.3
  • 6
    • 13844267823 scopus 로고    scopus 로고
    • Initial risk assessment for three beta-blockers found in the aquatic environment
    • Cleuvers M. Initial risk assessment for three beta-blockers found in the aquatic environment. Chemosphere 2005;59:199-205.
    • (2005) Chemosphere , vol.59 , pp. 199-205
    • Cleuvers, M.1
  • 7
    • 0345701334 scopus 로고    scopus 로고
    • Brooks BW, Foran CM, Richards SM, Weston J, Turner PK, Stanley JK, Solomon KR, Slattery M, La Point TW. Aquatic ecotoxicology of fluoxetine. Toxicol Lett 2003;142:169-183.
    • Brooks BW, Foran CM, Richards SM, Weston J, Turner PK, Stanley JK, Solomon KR, Slattery M, La Point TW. Aquatic ecotoxicology of fluoxetine. Toxicol Lett 2003;142:169-183.
  • 8
    • 31944449816 scopus 로고    scopus 로고
    • Environmental risk assessment of pharmaceutical residues in wastewater effluents, surface waters and sediments
    • Hernando MD, Mezcua M, Fernández-Alba AR, Barceló D. Environmental risk assessment of pharmaceutical residues in wastewater effluents, surface waters and sediments. Talanta 2006;69:334-342.
    • (2006) Talanta , vol.69 , pp. 334-342
    • Hernando, M.D.1    Mezcua, M.2    Fernández-Alba, A.R.3    Barceló, D.4
  • 9
    • 34547546696 scopus 로고    scopus 로고
    • Enantiospecific sublethal effects of the antidepressant fluoxetine to a model aquatic vertebrate and invertebrate
    • Stanley JK, Ramirez AJ, Chambliss CK, Brooks BW. Enantiospecific sublethal effects of the antidepressant fluoxetine to a model aquatic vertebrate and invertebrate. Chemosphere 2007;69:9-16.
    • (2007) Chemosphere , vol.69 , pp. 9-16
    • Stanley, J.K.1    Ramirez, A.J.2    Chambliss, C.K.3    Brooks, B.W.4
  • 10
    • 28444479427 scopus 로고    scopus 로고
    • Use of the chiral pharmaceutical propranolol to identify sewage discharges into surface waters
    • Fono LJ, Sedlak DL. Use of the chiral pharmaceutical propranolol to identify sewage discharges into surface waters. Environ Sci Technol 2005;393:9244-9252.
    • (2005) Environ Sci Technol , vol.393 , pp. 9244-9252
    • Fono, L.J.1    Sedlak, D.L.2
  • 11
    • 33749016750 scopus 로고    scopus 로고
    • Environmental fate processes and biochemical transformations of chiral emerging organic pollutants
    • Wong CS. Environmental fate processes and biochemical transformations of chiral emerging organic pollutants. Anal Bioanal Chem 2006;386:544-558.
    • (2006) Anal Bioanal Chem , vol.386 , pp. 544-558
    • Wong, C.S.1
  • 12
    • 70349517705 scopus 로고    scopus 로고
    • Protoxkit F™. Freshwater toxicity test with a ciliate protozoan. Standard Operational Procedure. Creasel: Deinze, Belgium; 1998.
    • Protoxkit F™. Freshwater toxicity test with a ciliate protozoan. Standard Operational Procedure. Creasel: Deinze, Belgium; 1998.
  • 13
    • 70349523878 scopus 로고    scopus 로고
    • Daphtoxkit F™ magna. Crustacean toxicity screening test for freshwater. Standard Operational Procedure. Creasel: Deinze, Belgium; 1996.
    • Daphtoxkit F™ magna. Crustacean toxicity screening test for freshwater. Standard Operational Procedure. Creasel: Deinze, Belgium; 1996.
  • 14
    • 70349536722 scopus 로고    scopus 로고
    • OECD. OECD guidelines for testing of chemicals. Section 2, effects on biotic systems. Daphnia sp. Acute immobilisation test and reproduction test 1984; Protocol 202:1-16.
    • OECD. OECD guidelines for testing of chemicals. Section 2, effects on biotic systems. Daphnia sp. Acute immobilisation test and reproduction test 1984; Protocol 202:1-16.
  • 15
    • 70349541693 scopus 로고    scopus 로고
    • ISO. Water quality: determination of the inhibition of the mobility of Daphnia magna Straus (Cladocera, Crustacea). ISO 6341. Geneva: International Organization for Standardization; 1996.
    • ISO. Water quality: determination of the inhibition of the mobility of Daphnia magna Straus (Cladocera, Crustacea). ISO 6341. Geneva: International Organization for Standardization; 1996.
  • 16
    • 70349550608 scopus 로고    scopus 로고
    • Commission of the European Communities. Methods for determination of ecotoxicity; Annex V, C. 2, Daphnia, acute toxicity to Daphnia L 383A, EEC Directive 92/69/EEC 1992;172-178.
    • Commission of the European Communities. Methods for determination of ecotoxicity; Annex V, C. 2, Daphnia, acute toxicity to Daphnia L 383A, EEC Directive 92/69/EEC 1992;172-178.
  • 17
    • 70349554904 scopus 로고    scopus 로고
    • Algaltoxkit F™. Freshwater toxicity test with microalgae. Standard Operational Procedure. Creasel: Deinze, Belgium; 1996.
    • Algaltoxkit F™. Freshwater toxicity test with microalgae. Standard Operational Procedure. Creasel: Deinze, Belgium; 1996.
  • 18
    • 70349543461 scopus 로고
    • OECD Guidelines for Testing of Chemicals. Section 2, effects on biotic systems
    • OECD, Method 201. Paris, France: OECD;
    • OECD. OECD Guidelines for Testing of Chemicals. Section 2, effects on biotic systems. Alga growth inhibition test. Method 201. Paris, France: OECD; 1984.
    • (1984) Alga growth inhibition test
  • 19
    • 70349539500 scopus 로고    scopus 로고
    • ISO. Water quality: fresh water algal growth inhibition test with Scenedesmus subspicatus and Selenastrum capricornutum. ISO 8692. Geneva: International Organization for Standardization; 1989.
    • ISO. Water quality: fresh water algal growth inhibition test with Scenedesmus subspicatus and Selenastrum capricornutum. ISO 8692. Geneva: International Organization for Standardization; 1989.
  • 20
    • 70349530486 scopus 로고    scopus 로고
    • Commission of the European Communities. Methods for determination of ecotoxicity; Annex V, C. 3, Algal inhibition test, L 383A, EEC Directive 92/69/EEC 1993;179-186.
    • Commission of the European Communities. Methods for determination of ecotoxicity; Annex V, C. 3, Algal inhibition test, L 383A, EEC Directive 92/69/EEC 1993;179-186.
  • 21
    • 0043134980 scopus 로고    scopus 로고
    • Probabilistic hazard assessment of environmentally occurring pharmaceuticals toxicity to fish, daphnids and algae by ECOSAR screening
    • Sanderson H, Johnson DJ, Wilson CJ, Brain RA, Solomon KR. Probabilistic hazard assessment of environmentally occurring pharmaceuticals toxicity to fish, daphnids and algae by ECOSAR screening. Toxicol Lett 2003;144:383-395.
    • (2003) Toxicol Lett , vol.144 , pp. 383-395
    • Sanderson, H.1    Johnson, D.J.2    Wilson, C.J.3    Brain, R.A.4    Solomon, K.R.5
  • 22
    • 70349541694 scopus 로고    scopus 로고
    • ECOSAR database. Available at
    • ECOSAR database. Available at: http://www.uoguelph.ca/~hsander.
  • 24
    • 0028892004 scopus 로고
    • Toxicity evaluations of wastewaters in Austria with conventional and cost-effective bioassays
    • Muna L, Persoone G, Janssen C, DeCoen W, Svardal K. Toxicity evaluations of wastewaters in Austria with conventional and cost-effective bioassays. Ecotoxicol Environ Saf 1995;32:139-146.
    • (1995) Ecotoxicol Environ Saf , vol.32 , pp. 139-146
    • Muna, L.1    Persoone, G.2    Janssen, C.3    DeCoen, W.4    Svardal, K.5
  • 25
    • 0014673226 scopus 로고
    • Modification of parkinsonism - chronic treatment with L-dopa
    • Cotzias GC, Papavasiliou PS, Gellene R. Modification of parkinsonism - chronic treatment with L-dopa. N Engl J Med 1969;280:337-345.
    • (1969) N Engl J Med , vol.280 , pp. 337-345
    • Cotzias, G.C.1    Papavasiliou, P.S.2    Gellene, R.3
  • 26
    • 0035735019 scopus 로고    scopus 로고
    • Stereospecific pharmacokinetics and pharmacodynamics of beta-adrenergic blockers in humans
    • Mehvar R, Brocks DR. Stereospecific pharmacokinetics and pharmacodynamics of beta-adrenergic blockers in humans. J Pharm Pharm Sci 2001;4:185-200.
    • (2001) J Pharm Pharm Sci , vol.4 , pp. 185-200
    • Mehvar, R.1    Brocks, D.R.2
  • 27
    • 0034690742 scopus 로고    scopus 로고
    • Presence of therapeutic drugs in the environment
    • Zuccato E, Calamari D, Natangelo M, Fanelli R. Presence of therapeutic drugs in the environment. Lancet 2000;355:1789-1790.
    • (2000) Lancet , vol.355 , pp. 1789-1790
    • Zuccato, E.1    Calamari, D.2    Natangelo, M.3    Fanelli, R.4
  • 28
    • 0012905958 scopus 로고    scopus 로고
    • Brooks BW, Turner PK, Stanley JK, Weston JJ, Glidewell EA, Foran CM, Slattery M, La Point TW, Huggett DB. Waterborne and sediment toxicity of fluoxetine to select organisms. Chemosphere 2003;52:135-142.
    • Brooks BW, Turner PK, Stanley JK, Weston JJ, Glidewell EA, Foran CM, Slattery M, La Point TW, Huggett DB. Waterborne and sediment toxicity of fluoxetine to select organisms. Chemosphere 2003;52:135-142.


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