Reversal effect of PI3-K inhibitor LY294002 on P-glycoprotein-mediated multidrug resistance of human leukemia cell line K562/DNR and gastric cancer cell line SGC7901/ADR
ARTICLE;
CANCER CELL CULTURE;
CANCER RESISTANCE;
CELL PROLIFERATION;
CONCENTRATION RESPONSE;
CONTROLLED STUDY;
CYTOTOXICITY TEST;
DRUG EFFICACY;
DRUG SENSITIVITY;
ENZYME INHIBITION;
FLOW CYTOMETRY;
GENE OVEREXPRESSION;
HUMAN;
HUMAN CELL;
IC 50;
LEUKEMIA;
LEUKEMIA CELL;
MULTIDRUG RESISTANCE;
PROTEIN EXPRESSION;
STOMACH CANCER;
WESTERN BLOTTING;
Proteasome inhibitors can alter the signaling pathways and attenuate the P-glycoprotein-mediated multidrug resistance [J]
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