Intrinsic, nondeterministic circadian rhythm generation in identified mammalian neurons

Proceedings of the National Academy of Sciences of the United States of America

Volumn 106, Issue 38, 2009, Pages 16493-16498

  Webb, Alexis B ^a   Angelo, Nikhil ^a   Huettner, James E ^a   Herzog, Erik D ^a  

^a WASHINGTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Luciferase; Pacemaker; Period gene; Suprachiasmatic nucleus; Vasoactive intestinal polypeptide

Indexed keywords

ARGIPRESSIN; FORSKOLIN; NEUROPEPTIDE; PER2 PROTEIN; TETRODOTOXIN; VASOACTIVE INTESTINAL POLYPEPTIDE;

ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; CELL CULTURE; CELL ISOLATION; CIRCADIAN RHYTHM; CONTROLLED STUDY; GENE EXPRESSION; IMMUNOHISTOCHEMISTRY; MAMMAL; MOUSE; NERVE CELL; NONHUMAN; PHENOTYPE; PRIORITY JOURNAL; SUPRACHIASMATIC NUCLEUS; SYNAPSE;

ANIMALS; ARGININE VASOPRESSIN; CELL CYCLE PROTEINS; CELLS, CULTURED; CIRCADIAN RHYTHM; GENE KNOCK-IN TECHNIQUES; IMMUNOHISTOCHEMISTRY; LUCIFERASES; LUMINESCENT MEASUREMENTS; MICE; MICE, INBRED C57BL; NEURONS; NUCLEAR PROTEINS; PATCH-CLAMP TECHNIQUES; SUPRACHIASMATIC NUCLEUS; TISSUE CULTURE TECHNIQUES; TRANSCRIPTION FACTORS; VASOACTIVE INTESTINAL PEPTIDE;

MAMMALIA;

EID: 70349499237     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.0902768106     Document Type: Article

References (48)

1. Reppert SM, Weaver DR (2002) Coordination of circadian timing in mammals. Nature 418:935-941.
2. Bae K, et al. (2001) Differential functions of mPer1, mPer2, and mPer3 in the SCN circadian clock. Neuron 30:525-536. (Pubitemid 32530594)
3. Nagoshi E, et al. (2004) Circadian gene expression in individual fibroblasts: Cellautonomous and self-sustained oscillators pass time to daughter cells. Cell 119:693-705. (Pubitemid 39535756)
4. Welsh DK, Yoo SH, Liu AC, Takahashi JS, Kay SA (2004) Bioluminescence imaging of individual fibroblasts reveals persistent, independently phased circadian rhythms of clock gene expression. Curr Biol 14:2289-2295.
5. Ralph MR, Foster RG, Davis FC, Menaker M (1990) Transplanted suprachiasmatic nucleus determines circadian period. Science 247:975-978. (Pubitemid 20081665)
6. Welsh DK, Logothetis DE, Meister M, Reppert SM (1995) Individual neurons dissociated from rat suprachiasmatic nucleus express independently phased circadian firing rhythms. Neuron 14:697-706.
7. Liu AC, et al. (2007) Intercellular coupling confers robustness against mutations in the SCN circadian clock network. Cell 129:605-616.
8. Yamaguchi S, et al. (2003) Synchronization of cellular clocks in the suprachiasmatic nucleus. Science 302:1408-1412. (Pubitemid 37452185)
9. Maywood ES, et al. (2006) Synchronization and maintenance of timekeeping in suprachiasmatic circadian clock cells by neuropeptidergic signaling. Curr Biol 16:599-605.
10. Antle MC, Silver R (2005) Orchestrating time: Arrangements of the brain circadian clock. Trends Neurosci 28:145-151. (Pubitemid 40320760)
11. Abrahamson EE, Moore RY (2001) Suprachiasmatic nucleus in the mouse: Retinal innervation, intrinsic organization and efferent projections. Brain Res 916:172-191.
12. Shinohara K, Honma S, Katsuno Y, Abe H, Honma KI (1995) Two distinct oscillators in the rat suprachiasmatic nucleus in vitro. Proc Natl Acad Sci USA 92:7396-7400.
13. De la Iglesia HO, Cambras T, Schwartz WJ, Diez-Noguera A (2004) Forced desynchronization of dual circadian oscillators within the rat suprachiasmatic nucleus. Curr Biol 14:796-800. (Pubitemid 38583715)
14. Noguchi T, Watanabe K, Ogura A, Yamaoka S (2004) The clock in the dorsal suprachiasmatic nucleus runs faster than that in the ventral. Eur J Neurosci 20:3199-3202. (Pubitemid 40007316)
15. Aton SJ, Colwell CS, Harmar AJ, Waschek J, Herzog ED (2005) Vasoactive intestinal polypeptide mediates circadian rhythmicity and synchrony in mammalian clock neurons. Nat Neurosci 8:476-483. (Pubitemid 41007565)
16. Herzog ED, Takahashi JS, Block GD (1998) Clock controls circadian period in isolated suprachiasmatic nucleus neurons. Nat Neurosci 1:708-713.
17. Honma S, Shirakawa T, Katsuno Y, Namihira M, Honma KI (1998) Circadian periods of single suprachiasmatic neurons in rats. Neurosci Lett 250:157-160. (Pubitemid 28355801)
18. Yoo SH, et al. (2004) Period2::luciferase real-time reporting of circadian dynamics reveals persistent circadian oscillations in mouse peripheral tissues. Proc Natl Acad Sci USA 102:1-8.
19. Aton SJ, Huettner JE, Straume M, Herzog ED (2006) GABA and Gi/o differentially control circadian rhythms and synchrony in clock neurons. Proc Natl Acad Sci USA 103:19188-19193. (Pubitemid 350002848)
20. Prolo LM, Takahashi JS, Herzog ED (2005) Circadian rhythm generation and entrainment in astrocytes. J Neurosci 25:404-408. (Pubitemid 40105610)
21. Mihalcescu I, Hsing W, Leibler S (2004) Resilient circadian oscillator revealed in individual cyanobacteria. Nature 430:81-85. (Pubitemid 38915228)
22. Roenneberg T, Morse D (1993) Two circadian oscillators in one cell. Nature 362:362-364. (Pubitemid 23101312)
23. Michel S, Geusz ME, Zaritsky JJ, Block GD (1993) Circadian rhythm in membrane conductance expressed in isolated neurons. Science 259:239-241. (Pubitemid 23041802)
24. Forger DB, Peskin CS (2004) Stochastic simulation of the mammalian circadian clock. Proc Natl Acad Sci USA 102:321-324.
25. Gonze D, Goldbeter A (2006) Circadian rhythms and molecular noise. Chaos 16:26110-26111.
26. Bernard S, Gonze D, Cajavec B, Herzel H, Kramer A (2007) Synchronization-induced rhythmicity of circadian oscillators in the suprachiasmatic nucleus. PLoS Comput Biol 3:e68. (Pubitemid 46683449)
27. To TL, Henson MA, Herzog ED, Doyle FJ, III (2007) A molecular model for intercellular synchronization in the mammalian circadian clock. Biophys J 92:3792-3803.
28. Antle MC, Foley DK, Foley NC, Silver R (2003) Gates and oscillators:Anetwork model of the brain clock. J Biol Rhythms 18:339-350.
29. Antle MC, Foley NC, Foley DK, Silver R (2007) Gates and oscillators II: Zeitgebers and the network model of the brain clock. J Biol Rhythms 22:14-25.
30. Raj A, van Oudenaarden A (2008) Nature, nurture, or chance: Stochastic gene expression and its consequences. Cell 135:216-226.
31. Wulbeck C, Grieshaber E, Helfrich-Forster C (2008) Pigment-dispersing factor (PDF) has different effects on Drosophila's circadian clocks in the accessory medulla and in the dorsal brain. J Biol Rhythms 23:409-424.
32. Herzog ED, Aton SJ, Numano R, Sakaki Y, Tei H (2004) Temporal precision in the mammalian circadian system: A reliable clock from less reliable neurons. J Biol Rhythms 19:35-46. (Pubitemid 38084513)
33. Inagaki N, Honma S, Ono D, Tanahashi Y, Honma KI (2007) Separate oscillating cell groups in mouse suprachiasmatic nucleus couple photoperiodically to the onset and end of daily activity. Proc Natl Acad Sci USA 104:7664-7669. (Pubitemid 47185963)
34. Ciarleglio CM, et al. (2009) Population encoding by circadian clock neurons organizes circadian behavior. J Neurosci 29:1670-1676.
35. Marder E, Goaillard JM (2006) Variability, compensation and homeostasis in neuron and network function. Nat Rev Neurosci 7:563-574. (Pubitemid 43995432)
36. Colwell CS, et al. (2003) Disrupted circadian rhythms in VIP and PHI deficient mice. Am J Physiol Regul Integr Comp Physiol 285:R939-R949.
37. Gallego M, Eide EJ, Woolf MF, Virshup DM, Forger DB (2006) An opposite role for tau in circadian rhythms revealed by mathematical modeling. Proc Natl Acad Sci USA 103:10616-10623. (Pubitemid 44078026)
38. Xu Y, et al. (2007) Modeling of a human circadian mutation yields insights into clock regulation by PER2. Cell 128:59-70. (Pubitemid 46048889)
39. Meng QJ, et al. (2008) Setting clock speed in mammals: The CK1epsilontau mutation in mice accelerates circadian pacemakers by selectively destabilizing PERIOD proteins. Neuron 58:78-88.
40. Schaap J, et al. (2003) Heterogeneity of rhythmic suprachiasmatic nucleus neurons: Implications for circadian waveform and photoperiodic encoding. Proc Natl Acad Sci USA 100:15994-15999. (Pubitemid 38021103)
41. Sladek M, et al. (2004) Insight into molecular core clock mechanism of embryonic and early postnatal rat suprachiasmatic nucleus. Proc Natl Acad Sci USA 101:6231-6236. (Pubitemid 38520557)
42. Vanderleest HT, et al. (2007) Seasonal encoding by the circadian pacemaker of the SCN. Curr Biol 17:468-473.
43. Sumova A, Kovacikova Z, Illnerova H (2007) Dynamics of the adjustment of clock gene expression in the rat suprachiasmatic nucleus to an asymmetrical change from a long to a short photoperiod. J Biol Rhythms 22:259-267. (Pubitemid 46798989)
44. Banker G, Goslin K (1991) in Culturing Nerve Cells, eds Banker G, Goslin K (MIT Press, Cambridge), pp 75-118.
45. Meister M, Pine J, Baylor DA (1994) Multi-neuronal signalsfromthe retina: Acquisition and analysis. J Neurosci Methods 51:95-106. (Pubitemid 24089277)
46. Plautz JD, et al. (1997) Quantitative analysis of Drosophila period gene transcription in living animals. J Biol Rhythms 12:204-217.
47. Sokolove PG, Bushell WN (1978) The chi square periodogram: Its utility for analysis of circadian rhythms. J Theor Biol 72:131-160.
48. Green DM, Swets JA (1966) Signal Detection Theory and Psychophysics (Wiley, New York).