On-chip assay for determining the inhibitory effects and modes of action of drugs against xanthine oxidase

Journal of Pharmaceutical and Biomedical Analysis

Volumn 51, Issue 1, 2010, Pages 1-6

  Naoghare, Pravin K ^a   Kwon, Ho Taik ^b   Song, Joon Myong ^a  

^a Seoul National University   (South Korea)

^b Celltek Co Ltd   (South Korea)

Author keywords

Drug discovery screening; High throughput screening; Nitroblue tetrazolium; Photodiode array; Xanthine oxidase

Indexed keywords

AMINOGLUTETHIMIDE; CYCLOSPORIN A; DITHRANOL; FORMAZAN; NARINGENIN; NITROBLUE TETRAZOLIUM; SUPEROXIDE DISMUTASE; XANTHINE OXIDASE;

ACCURACY; ARTICLE; COLORIMETRY; CONTROLLED STUDY; DRUG MECHANISM; DRUG SCREENING; ENZYME IMMOBILIZATION; ENZYME INHIBITION; HIGH THROUGHPUT SCREENING; MICROCHIP ANALYSIS; PRIORITY JOURNAL; QUANTITATIVE ANALYSIS; SURFACE PLASMON RESONANCE;

BIOLOGICAL ASSAY; COLORIMETRY; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG DISCOVERY; ENZYME INHIBITORS; HUMANS; MICROCHIP ANALYTICAL PROCEDURES; NITROBLUE TETRAZOLIUM; REPRODUCIBILITY OF RESULTS; SUPEROXIDE DISMUTASE; XANTHINE OXIDASE;

EID: 70349451973     PISSN: 07317085     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jpba.2009.07.020     Document Type: Article

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